Anti Inflammatory Drugs
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Anti Inflammatory Drugs
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Author :
language : en
Publisher:
Release Date : 1979
Anti Inflammatory Drugs written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with categories.
Nonsteroidal Anti Inflammatory Drugs
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Author : Ali Al-Kaf
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-08-23
Nonsteroidal Anti Inflammatory Drugs written by Ali Al-Kaf and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-23 with Medical categories.
This book intends to provide the reader with a comprehensive overview about the state of the art regarding the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in physical and rehabilitation medicine and the study of the pharmacodynamics of existing and newly introduced NSAIDs in the management of pain and inflammation. It will also elaborate and refine already known knowledge on the mechanism(s) of nonsteroidal anti-inflammatory agents. This book may provide additional knowledge about the design and development of new drug delivery systems loaded with NSAIDs potentially useful in the treatment of chronic inflammatory-based diseases following circadian cycle, uses of NSAIDs as a source of medicinal plants, and the adverse effects and drug interactions of the nonsteroidal anti-inflammatory drugs.
Side Effects Of Anti Inflammatory Drugs 3
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Author : K. D. Rainsford
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Side Effects Of Anti Inflammatory Drugs 3 written by K. D. Rainsford and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The contents of this book represent papers which were presented at the Third International Meeting on "Side-Effects of Anti-Inflammatory and Analgesic Drugs" which was held under the auspices of the University of Verona, Institute of Pharmacology in Verona on 8-11 May 1991. This meeting was held in conjunction with the 13th European Workshop on Inflammation and although publications from this part of the meeting are not published here (they appear in Agents and Actions), we were fortunate in having a group of people interested in inflammation from varying backgrounds. The success of the third meeting followed previous meetings held in Cambridge and Verona respectively and continue a tradition which has now become well established. The meeting brought together physicians, scientists and those concerned with the production and use of anti-inflammatory drugs to a very stimulating conference to discuss basic issues affecting all aspects of side-effects of anti-inflammatory and analgesic drugs as well as their detection and treatment. The meeting was held in the Auditorium of Glaxo Italy and we are very grateful to that company for use of their facilities as well as to the University of Verona, Institute of Pharmacology, for valuable secretarial and administrative help. The success of the conference would not have been possible without valuable financial assistance of the companies listed separately (under Acknowledgements) as well as to the organizers of the 13th European Workshop on Inflammation who collaborated with us.
The Search For Anti Inflammatory Drugs
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Author : Vincent J. Merluzzi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Search For Anti Inflammatory Drugs written by Vincent J. Merluzzi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Perspectives on Anti-Inflammatory Drugs Inflammation is a very complicated process of interrelated events and cas cades that does not allow for an easily defined, focused attack for drug discovery. It is evident from years of research and development that certain classes of compounds (e.g., NSAIDs, steroids, and so on) have had a meas ure of success in alleviating pain and even dampening cellularlhormonal mechanisms involved in the process. Clear, mechanism-related therapies (e.g., for arthritis) and targeted drugs (e.g., for transplantation) have not been available in the past and, in reality, research in inflammation has re lied on more phenomenological approaches for resolving symptoms or on blatant cytoreductive approaches in cases like organ transplantation. In the last decade, approaches that have revealed novel cellular pathways in which intervention is possible for lymphocyte regulation (for example, cyclosporine and FK506) and small molecular weight mediators (e.g., leu kotriene inhibitors) are now either standard therapy or will be in a short time. These latter approaches have been the result of research from the 1970s up to the present.
Side Effects Of Anti Inflammatory Drugs
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Author : K. D. Rainsford
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Side Effects Of Anti Inflammatory Drugs written by K. D. Rainsford and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
These two volumes contain the proceedings of a 3 day international meeting held at the University of Cambidge and Queens' College Cambridge from 31st July to 2nd August 1985 on the Side-Effects of Anti-Inflammatory Analgesic Drugs. The first meeting was held in Verona, (Italy) in 1982 and the organisers felt that, with a number of recent developments including the withdrawal of a num ber of new anti-inflammatory drugs, and concern being expressed in the lay and specialist medical press and other media about the safety of these drugs, that it was appropriate to have a second such meeting. The meeting was attended by some 300 delegates and the dis cussion focussed most intently on the recent issues, e. g. the value of adverse drug reaction reporting of the non-steroidal anti inflammatory (NSAI) drugs, certain side-effects associated with particular NSAI drugs, the predictive value of animal models etc. Organising a meeting de novo without outside help would not have been possible without the immensely valuable help given en thusiastically by people and financial assistance given most generously by those pharmaceutical companies listed below. These financial contributions were given despite current economic dif ficulties and moves to restrict the proportion of profits towards educational activities.
Non Steroidal Anti Inflammatory Drugs In Water
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Author : Leobardo Manuel Gómez-Oliván
language : en
Publisher: Springer Nature
Release Date : 2020-10-14
Non Steroidal Anti Inflammatory Drugs In Water written by Leobardo Manuel Gómez-Oliván and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-14 with Science categories.
This book gathers the main international research findings on non-steroidal anti-inflammatory drugs (NSAIDs) as emerging contaminants in water. It focuses on the major routes of exposure, and the destinations and life cycles of NSAIDs in water, as well as the manifestations of toxicity in different organisms. It also reviews the methods used in the detection, analysis and quantification of NSAIDs in water as well as the biological and chemical methods of removing them. Lastly, the book offers an overview of the legal frameworks in place and provides conclusions and recommendations for the future. Given its scope, the book is an indispensable resource for scientists in academia and industry, as well as for decision-makers involved in contamination assessment and environmental analysis and NGOs interested in the problem of water contamination by NSAIDs.
Side Effects Of Anti Inflammatory Drugs
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Author : K. D. Rainsford
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Side Effects Of Anti Inflammatory Drugs written by K. D. Rainsford and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Non Steroidal Anti Inflammatory Drugs
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Author : IARC Working Group on the Evaluation of Cancer-preventive Agents
language : en
Publisher: IARC
Release Date : 1997
Non Steroidal Anti Inflammatory Drugs written by IARC Working Group on the Evaluation of Cancer-preventive Agents and has been published by IARC this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Anti-inflammatory agents categories.
Nsaids
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Author : Swamlata Saraf
language : en
Publisher:
Release Date : 2008
Nsaids written by Swamlata Saraf and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Nonsteroidal anti-inflammatory agents categories.
Improved Non Steroid Anti Inflammatory Drugs Cox 2 Enzyme Inhibitors
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Author : Sir John R. Vane
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Improved Non Steroid Anti Inflammatory Drugs Cox 2 Enzyme Inhibitors written by Sir John R. Vane and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In 1971, Vane proposed that the mechanism of action of the aspirin-like drugs was through their inhibition of prostaglandin biosynthesis. Since then, there has been intense interest in the interaction between this diverse group of inhibitors and the enzyme known as cyclooxygenase (COX). It exists in two isoforms, COX-l and COX-2 (discovered some 5 years ago). Over the last two decades several new drugs have reached the market based on COX-l enzyme screens. Elucidation of the three-dimensional structure of COX-l has provided a new understanding for the actions of COX inhibitors. The constitutive isoform of COX, COX-l has clear physiological functions. Its activation leads, for instance, to the production of prostacyclin which when released by the endothelium is anti-thrombogenic and anti-atherosclerotic, and in the gastric mucosa is cyto protective. COX-l also generates prostaglandins in the kidney, where they help to maintain blood flow and promote natriuresis. The inducible isoform, COX-2, was discovered through its activity being increased in a number of cells by pro inflammatory stimuli. A year or so later, COX-2 was identified as a distinct isoform encoded by a different gene from COX-I. COX-2 is induced by inflammatory stimuli and by cytokines in migratory and other cells. Thus the anti-inflammatory actions of non-steroid anti-inflammatory drugs (NSAIDs) may be due to the inhibition of COX-2, whereas the unwanted side-effects such as irritation of the stomach lining and toxic effects on the kidney are due to inhibition of the constitutive enzyme, COX-I.