Antimicrobial Resistance New Insights
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Antimicrobial Resistance New Insights
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Author : Ghulam Mustafa
language : en
Publisher: BoD – Books on Demand
Release Date : 2025-06-25
Antimicrobial Resistance New Insights written by Ghulam Mustafa and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with Science categories.
This comprehensive book provides a timely and authoritative overview of the latest advances in antimicrobial resistance (AMR), bringing together leading experts to share their knowledge on the complex mechanisms of AMR and the latest clinical recommendations for diagnosis, treatment, and prevention. The book delves into how AMR is a critical global health threat driven by the misuse of antibiotics in medicine, agriculture, and the environment, undermining treatment effectiveness and food security. The volume highlights urgent needs for molecular research, global collaboration, and innovative solutions such as nanotechnology and alternative therapies to combat the spread of multidrug-resistant pathogens. It also emphasizes the importance of responsible antimicrobial use, improved surveillance, and coordinated action across sectors to manage and prevent AMR sustainably. With a balanced view of the current state of knowledge, this book highlights areas of uncertainty and controversy and identifies future research directions. The book is an essential resource for researchers and clinicians seeking to stay up-to-date with the latest advances, students and academics looking for a comprehensive and authoritative textbook, and industry professionals and policymakers interested in understanding the latest developments and challenges in the field. The book will provide them a unique opportunity to explore the complex interplay between AMR and gain a deeper understanding of the challenges and opportunities that lie ahead, ultimately aiming to contribute to developing effective strategies to combat AMR and improve human health globally. This book is a self-contained collection of scholarly papers targeting an audience of practicing medical and basic researchers, academicians, MD/Ph.D. students and scientists.
Antimicrobial Resistance
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Author : Mihai Mareș
language : en
Publisher:
Release Date : 2021
Antimicrobial Resistance written by Mihai Mareș and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Drug resistance in microorganisms categories.
New Insights Into The Transmission Dynamics And Control Of Antimicrobial Resistance To Last Resort Antibiotics
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Author : Zhi Ruan
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-05
New Insights Into The Transmission Dynamics And Control Of Antimicrobial Resistance To Last Resort Antibiotics written by Zhi Ruan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-05 with Science categories.
New Insights Updates On The Molecular Epidemiology And Antimicrobial Resistance Of Mrsa In Humans In The Whole Genome Sequencing Era
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Author : David Coleman
language : en
Publisher: Frontiers Media SA
Release Date : 2019-07-11
New Insights Updates On The Molecular Epidemiology And Antimicrobial Resistance Of Mrsa In Humans In The Whole Genome Sequencing Era written by David Coleman and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-11 with categories.
Methicillin-resistant Staphylococcus aureus (MRSA) have been a major cause of healthcare-associated (HA) infection globally for several decades. During this time many distinct clones have emerged independently around the world, some of which have achieved pandemic status. More recently, community-associated (CA) and livestock-associated MRSA clones have also emerged, some of which have become established in hospitals and other healthcare facilities, and sometimes have displaced previously predominant HA clones. Importantly, MRSA can frequently exhibit resistance to a wide range of clinically relevant antibiotics, which limits treatment options and complicates patient management and outcomes. Investigating routes of transmission and spread of MRSA in healthcare facilities have conventionally been undertaken by combining available epidemiological information with data from DNA-based typing systems such as pulse-field gel electrophoresis typing, spa typing, multilocus sequence typing, and more recently, DNA microarray profiling. However, these approaches can frequently lack the discriminatory ability to differentiate between MRSA isolates in healthcare environments where a relatively small number of clones may predominate. The advent of high-throughput whole genome sequencing (WGS) over the last decade with the development of affordable, easy-to-use benchtop DNA sequencing platforms, associated sequencing chemistry and bioinformatics tools, has revolutionized studies of MRSA epidemiology and evolution. The significantly enhanced discriminatory power and resolution afforded by WGS has also provided hitherto unimaginable insights into the origins, emergence and factors that drive the evolution of specific MRSA clones. Furthermore, WGS has highlighted the very significant contributions of mobile genetic elements (MGEs) encoding virulence factors and resistance genes from coagulase-negative staphylococcal (CoNS) species to the emergence and evolution of MRSA. This Research Topic brings together a collection of original research articles and up-to-date reviews that highlight the significant impact WGS is having on our understanding of the epidemiology and routes of transmission of HA- and CA-MRSA in humans and the phylogenetics and evolution of specific MRSA clones. The Research Topic also highlights the impact that WGS is having on our understanding of antimicrobial resistance in MRSA by acquisition of MGEs and the role of specific CoNS species in the origins and evolution of particular MGEs that can promote the survival of MRSA following acquisition. Finally, the Research Topic highlights the immense potential impact of WGS technology in surveillance, rapid pathogen detection, identification of virulence factor profiles and antibiotic resistance genotypes, possibly from clinical samples directly.
New Insights In Antibiotic Resistance And Pneumococcal Vaccines
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Author : Ghulam Mustafa
language : en
Publisher: BoD – Books on Demand
Release Date : 2025-04-02
New Insights In Antibiotic Resistance And Pneumococcal Vaccines written by Ghulam Mustafa and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-02 with Medical categories.
Unravelling the complexities of antibiotic resistance and pneumococcal vaccines, this book provides a timely and authoritative overview of the latest advances in antibiotic resistance and pneumococcal vaccines, bringing together leading experts to share their knowledge on the complex mechanisms of antibiotic resistance, the development of novel pneumococcal vaccines, and the latest clinical recommendations for diagnosis, treatment, and prevention. The book investigates the mechanisms of antibiotic resistance and the genetics of resistance, as well as the development of novel pneumococcal vaccines, including protein-based and polysaccharide conjugate vaccines, and explores the application of metagenomics and bioinformatics in understanding pneumococcal disease. With a balanced view of the current state of knowledge, highlighting areas of uncertainty and controversy, as well as identifying future research directions, this book is an essential resource for researchers and clinicians seeking to stay up-to-date with the latest advances, students and academics looking for a comprehensive and authoritative textbook, and industry professionals and policymakers interested in understanding the latest developments and challenges in the field, providing a unique opportunity to explore the complex interplay between antibiotic resistance and pneumococcal vaccines, and to gain a deeper understanding of the challenges and opportunities that lie ahead, ultimately aiming to contribute to the development of effective strategies to combat antibiotic resistance and pneumococcal disease, and to improve human health globally. This book is a self-contained collection of scholarly papers targeting an audience of practising medical and basic researchers, academicians, MD/Ph.D. students, and scientists.
How To Overcome The Antibiotic Crisis
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Author : Marc Stadler
language : en
Publisher: Springer
Release Date : 2016-12-21
How To Overcome The Antibiotic Crisis written by Marc Stadler and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-21 with Medical categories.
This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused by multi-resistant bacteria. It covers several basic aspects, such as the evolution of antibiotic resistance and the influence of antibiotics on the gut microbiota, and addresses the search for novel pathogenicity blockers as well as historical aspects of antibiotics. Further topics include applied aspects, such as drug discovery based on biodiversity and genome mining, optimization of lead structures by medicinal chemistry, total synthesis and drug delivery technologies. Moreover, the development of vaccines as a valid alternative therapeutic approach is outlined, while the importance of epidemiological studies on important bacterial pathogens, the problems arising from the excessive use of antibiotics in animal breeding, and the development of innovative technologies for diagnosing the “bad bugs” are discussed in detail. Accordingly, the book will appeal to researchers and clinicians alike.
New Insights Into The Future Of Pharmacoepidemiology And Drug Safety
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Author : Maria Teresa Herdeiro
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-10-13
New Insights Into The Future Of Pharmacoepidemiology And Drug Safety written by Maria Teresa Herdeiro and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-13 with Medical categories.
In the last decade, pharmacoepidemiology has emerged as an important field to study the use/effects of drugs in large populations in real life, allowing for improved benefits and effectiveness of drugs as well as a decline in drug-related risks. The correct assessment, reporting, monitoring, and prevention of adverse events in drugs’ development, as well as therapy and post-market surveillance, is essential to improve clinical therapies and health outcomes. This book provides a comprehensive and unique overview of the relevance, new insights, and recent findings of pharmacoepidemiology and drug safety in public health.
New Insights On Biofilm Antimicrobial Strategies
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Author : Luís Melo
language : en
Publisher: MDPI
Release Date : 2021-08-17
New Insights On Biofilm Antimicrobial Strategies written by Luís Melo and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-17 with Medical categories.
Over the last few decades, the study of microbial biofilms has been gaining interest among the scientific community. These microbial communities comprise cells adhered to surfaces that are surrounded by a self-produced exopolymeric matrix that protects biofilm cells against different external stresses. Biofilms can have a negative impact on different sectors within society, namely in agriculture, food industries, and veterinary and human health. As a consequence of their metabolic state and matrix protection, biofilm cells are very difficult to tackle with antibiotics or chemical disinfectants. Due to this problem, recent advances in the development of antibiotic alternatives or complementary strategies to prevent or control biofilms have been reported. This book includes different strategies to prevent biofilm formation or to control biofilm development and includes full research articles, reviews, a communication, and a perspective.
Mechanisms Of Antibiotic Resistance
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Author : Jun Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2015-06-01
Mechanisms Of Antibiotic Resistance written by Jun Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Antibiotics categories.
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Urinary Tract Infections New Insights
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Author : Wael Hegazy
language : en
Publisher: BoD – Books on Demand
Release Date : 2023-11-02
Urinary Tract Infections New Insights written by Wael Hegazy and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-02 with Medical categories.
Urinary tract infections (UTIs) can disrupt lives, causing discomfort, frustration, and anxiety. Drawing on the latest medical research, expert advice, and real-life experiences, this comprehensive guide provides a roadmap to urinary health. From the underlying mechanisms of UTIs to the most effective treatments, you will gain a deep understanding of this common condition. Written by experts in the field, this book combines cutting-edge medical research with real-life stories and experiences, creating a valuable resource for patients, caregivers, and healthcare professionals alike. Whether you are seeking answers for your own struggles or supporting a loved one through their UTI journey, this book equips you with the knowledge and tools to make informed decisions and achieve lasting urinary health.