Antioxidants And Stem Cells For Coronary Heart Disease
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Antioxidants And Stem Cells For Coronary Heart Disease
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Author : Philip B Oliva
language : en
Publisher: World Scientific
Release Date : 2014-01-22
Antioxidants And Stem Cells For Coronary Heart Disease written by Philip B Oliva and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-22 with Science categories.
This book covers two known controversial topics — antioxidants and stem cells as therapies to treat coronary heart disease. Aiming to provide college-educated but not scientifically trained readership with a wealth of information about these two cutting-edge technologies, Antioxidants and Stem Cells for Coronary Heart Disease is written with minimum scientific terminology. Basic science studies and clinical trials regarding stem cells and antioxidants are discussed and peppered with anecdotes to make them understandable and entertaining to the laymen. Contents:Part I:The French ParadoxLDL Oxidation — BrieflyAcetylation of LDLFree RadicalsThe Oxygen ParadoxRetrolental Fibroplasia from 1956 to 1972: The Quiet TimeThe Second Epidemic of Retrolental Fibroplasia: 1972–20??Cytokines and ChemokinesLDL Oxidation by Free Radicals — In DetailTwo Other Ways to Oxidize LDL: Lipoxygenase and Nitric OxideWhat is the Raison d'être for Oxidized LDL?Fatty Streaks and Foam CellsEmbryonic Stem CellsAdult Stem CellsTransgenic MicePart II:Treatment of Coronary Heart Disease with Antioxidants: An IntroductionThe Mediterranean DietAcute Myocardial Infarctions in Japan and Norway from 1910 to 1950Wine, Beer, and Spirits as AntioxidantsA Perspective on Antioxidant Vitamins for the Treatment of Coronary Heart DiseaseVitamin AThe Thalidomide SagaVitamin CVitamin EDo Combinations of Antioxidant Vitamins Work Better than Individual Vitamins in Patients with Coronary Heart Disease?A RequiemMolecular Markers, Reporter Genes and Suicide GenesStem Cells for the Heart: Hype or Hope?The PrizefightBrainbowCre/Lox: A Cut-and-Paste Method of Gene Swapping Without a Mac or PC and a New Scientific Term with Vast SignificanceBacteriophage, Transgenic Mice and Transgenic MarmosetsPhage Geometry and Soccer BallsEuler's FormulaE = mc2 and Einstein's BrainThe Manhattan Project and Its Connection with Albert EinsteinA Gadget, a Little Boy and a Fat ManCamillo Golgi and Santiago Ramón Y Cajal: Bitter Rivals to The End Readership: College-educated general public and non-scientists who are interested in the topic of antioxidants and stem cells. Key Features:The book is written in plain English and scientific jargons are explained in laymen terms“Hot topics” such as embryonic stem cells, adult stem cells and antioxidants are discussedA well-researched and colourfully illustrated book for readers of the general publicKeywords:Stem Cells;Antioxidants;Coronary Heart Disease
Studies On Cardiovascular Disorders
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Author : Heinrich Sauer
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-11
Studies On Cardiovascular Disorders written by Heinrich Sauer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-11 with Science categories.
This collection of articles on oxidative stress in clinical practice surveys essential current research in what is a rapidly evolving field. As well as giving the reader a mechanistic overview of how oxidative stress affects cardiovascular disease, it analyzes the potential of a number of therapeutic options that target these pathways. Understanding the complexity of the cellular redox system could lead to the development of better targeted interventions that facilitate patient recovery. Even as large-scale clinical trials of so-called ‘simple’ antioxidant approaches such as vitamins C and E show that significant benefits for cardiovascular patients remain elusive, Studies on Cardiovascular Disorders demonstrates that such approaches are too simplistic. Beginning with a summary of redox signaling models that could induce the progression of redox-associated cardiovascular disorders, the volume moves on to examine redox-mediated protein modification under physiological and pathophysiological conditions. It provides an outline of the signaling pathways in cardiovascular development during embryogenesis, and what impact these might have in the differentiation process of resident cardiac and blastocyst derived stem cells. Further chapters detail our current knowledge of the influence the sensory nervous system exerts on the cardiovascular system, and the paradoxical role of mitochondria-derived ROS in cardiac protection. In all, almost 30 contributions cover issues as diverse as the antioxidant properties of statins in the heart and the oxidative risk factors for cardiovascular disease in women. A range of medical practitioners will find the contents of Studies on Cardiovascular Disorders provides illuminating insight into the Janus-faced role of ROS in the cardiovascular system.
Antioxidants And Cardiovascular Disease
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Author : R Nath
language : en
Publisher: ALPHA SCIENCE INTERNATIONAL LIMITED
Release Date : 2004-01-01
Antioxidants And Cardiovascular Disease written by R Nath and has been published by ALPHA SCIENCE INTERNATIONAL LIMITED this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-01 with Medical categories.
This unique book authored by leading investigators in the field of Cardiovascular research and practicing clinicians across the globe details the scientific evidence for the heath effect of vitamins, antioxidants, trace elements and functional food, specifically their role in Cardiovascular system and provides up-to-date recommendations in the area of Cardiovascular nutrition including dietary micronutrients and supplements.Genetics of coronary disease as well as racial differences and risk factors, the role of Homocystine dietary fats, importance of antioxidant trace elements, genetic and racial differences especially in relation to cardiovascular effects, Clinical relevance of trace elements and minerals such as Chromium, Copper, Fluoride, Iron, Iodine, Molybdenum, Manganese, Selenium, Zinc, Calcium, Magnesium and Phosphorous have all been covered in relation to cardiovascular disease.
Oxidative Stress In Heart Diseases
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Author : Sajal Chakraborti
language : en
Publisher: Springer Nature
Release Date : 2019-11-06
Oxidative Stress In Heart Diseases written by Sajal Chakraborti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Science categories.
This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
Studies On Cardiovascular Disorders
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Author :
language : en
Publisher:
Release Date : 2011-04-01
Studies On Cardiovascular Disorders written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-01 with categories.
Modulation Of Oxidative Stress In Heart Disease
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Author : Sajal Chakraborti
language : en
Publisher: Springer Nature
Release Date : 2019-11-10
Modulation Of Oxidative Stress In Heart Disease written by Sajal Chakraborti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-10 with Science categories.
This book highlights the multifaceted roles of Reactive Oxygen Species (ROS) in modulating normal cellular and molecular mechanisms during the development of different types of heart disease. Each chapter in the book deals with the role that altered redox homeostasis plays in the pathophysiology of heart disease. In addition, the book explains how reactive oxidant species interact with their targets and provides novel strategies for attenuating oxidative stress-induced types of heart disease. The book not only covers ROS-induced response in heart disease at the cellular level, but also demonstrates that an imbalance of redox states has its roots in our genes, and explains the ways gene expression is regulated. In turn, it reviews potential sources of ROS, their pathological effects on the heart, and potential sites for therapeutic interventions.
Handbook Of Cardiac Stem Cell Therapy
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Author : Ioannis Dimarakis
language : en
Publisher: Imperial College Press
Release Date : 2009-01-01
Handbook Of Cardiac Stem Cell Therapy written by Ioannis Dimarakis and has been published by Imperial College Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-01 with Medical categories.
This book is an impressive compilation of contributions on the hot topic of cardiac stem cell therapy from leading groups all over the world. In the assembly of chapters, a structured approach is adopted; starting from the clinician's perspective, all developments in both the experimental and clinical research areas are covered. This journey will take the reader from the bench-top to the bedside, with all chapters written by leading authorities in their respective fields, including data still in press with medical journals.
Preventing Coronary Heart Disease
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Author : Lesley Rogers
language : en
Publisher:
Release Date : 1997
Preventing Coronary Heart Disease written by Lesley Rogers and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with categories.
Oxidative Stress And Vascular Disease
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Author : John F. Keaney Jr.
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Oxidative Stress And Vascular Disease written by John F. Keaney Jr. and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atherosclerosis; that hypercholesterolemia can be effectively treated; and that treatment significantly reduces not only coronary disease mortality but also all cause mortality. Treatment to lower plasma levels of cholesterol - primarily low density lipoprotein (LDL) cholesterol - is now accepted as best medical practice and both physicians and patients are being educated to take aggressive measures to lower LDL. We can confidently look forward to important decreases in the toll of coronary artery disease over the coming decades. However, there is still uncertainty as to the exact mechanisms by which elevated plasma cholesterol and LDL levels initiate and favor the progression of lesions. There is general consensus that one of the earliest responses to hypercholesterolemia is the adhesion of monocytes to aortic endothelial cells followed by their penetration into the subendothelial space, where they differentiate into macrophages. These cells, and also medial smooth muscle cells that have migrated into the subendothelial space, then become loaded with mUltiple, large droplets of cholesterol esters . . . the hallmark of the earliest visible atherosclerotic lesion, the so-called fatty streak. This lesion is the precursor of the more advanced lesions, both in animal models and in humans. Thus the centrality of hypercholesterolemia cannot be overstated. Still, the atherogenic process is complex and evolves over a long period of time.
Stem Cell And Tissue Engineering
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Author : Song Li
language : en
Publisher: World Scientific
Release Date : 2011
Stem Cell And Tissue Engineering written by Song Li and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students.