Application And Innovation Of Multiomics Technologies In Clinical Oncology

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Application And Innovation Of Multiomics Technologies In Clinical Oncology

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Author : Ye Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-26

Application And Innovation Of Multiomics Technologies In Clinical Oncology written by Ye Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-26 with Science categories.

Multi Omics Application In Exploring Potential Biomarkers Targeting Resistance Of Anti Cancer Drugs

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Author : Hailin Tang
language : en
Publisher: Frontiers Media SA
Release Date : 2025-04-30

Multi Omics Application In Exploring Potential Biomarkers Targeting Resistance Of Anti Cancer Drugs written by Hailin Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-30 with Science categories.

Cancer remains a critical concern in global health due to its high prevalence and mortality rates. Despite significant advancements in the development of anti-cancer drugs, drug resistance continues to pose a major challenge in clinical treatments. Drug resistance may be either intrinsic i.e., pre-existent resistance present in the tumor cells even before exposure to chemotherapy, or acquired resistance i.e., induced by drugs during or after treatment of tumors with anticancer compounds. Anti-cancer treatments such as chemotherapy, targeted therapy, and immunotherapy are highly genotype-related interventions. Coding and Non-coding RNAs (ncRNAs), such as microRNAs (miRNAs), lncRNAs, circular RNAs (circRNAs), and PIWI-RNA (piRNA) have been shown to play important roles in tumor formation and therapeutic resistance. lncRNAs can activate DNA damage repair, silence tumor suppressor genes, and modulate cancer-related epigenetic changes at the chromatin level in terms of histone modifications, DNA methylation, and altering chromatin architecture.

Applications Of Multi Omics

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Author : Richard Skiba
language : en
Publisher: After Midnight Publishing
Release Date : 2025-02-19

Applications Of Multi Omics written by Richard Skiba and has been published by After Midnight Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-19 with Medical categories.

In the era of big data and personalized medicine, Applications of Multi-Omics serves as a comprehensive guide to integrating biological data across genomics, transcriptomics, proteomics, metabolomics, and epigenomics. This book explores how multi-omics technologies provide a holistic view of biological systems, transforming our understanding of human health, disease mechanisms, drug development, and environmental science. Written for researchers, healthcare professionals, and students in life sciences, this book breaks down complex concepts into accessible insights, covering key methodologies, computational approaches, and real-world applications. From precision medicine and biomarker discovery to AI-driven data integration and ethical considerations, Applications of Multi-Omics provides a deep dive into how multi-layered biological data is revolutionizing biomedical research and healthcare. Whether you are an academic researcher seeking to integrate multi-omics in your studies, a clinician exploring omics-driven diagnostics, or a data scientist working at the intersection of AI and life sciences, this book is an essential resource. It highlights emerging trends, challenges, and future directions in multi-omics, paving the way for groundbreaking discoveries in personalized medicine, biotechnology, and agricultural research. Join the multi-omics revolution and uncover the intricate biological networks shaping the future of science and medicine.

Application Of Multi Omics Analysis In Thoracic Cancer Immunotherapy

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Author : Attila Szöllősi
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-19

Application Of Multi Omics Analysis In Thoracic Cancer Immunotherapy written by Attila Szöllősi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-19 with Medical categories.

Based on statistical data provided by the World Health Organization, cancer is widely acknowledged as the foremost contributor to global mortality and persists as a significant concern in the contemporary era. In recent times, immunotherapy has been demonstrated as an efficacious approach in diverse advanced solid tumors, especially in thoracic tumors, consequently emerging as a prominent area of focus in the investigation of antitumor pharmaceuticals. The utilization of immunotherapy directed towards programmed death ligand-1 (PD-L1) and programmed cell death protein-1 (PD-1) has emerged as a valid approach, resulting in substantial enhancements in both disease-free and overall survival rates among cancer patients. Moreover, applications of multi-omics analyses in thoracic tumors have made great progress. However, it also ushered in new challenges. Certain subtypes of thoracic cancer have been identified as immune-quiescent tumors, indicating that only a limited number of patients would derive benefits from immunotherapy while also experiencing a high incidence of severe adverse events. Besides, multi-omics analyses reveal patterns of drug resistance and relapse in the treatment of thoracic tumors, which help us identify the molecular mechanisms that lead to drug resistance and provide clues for overcoming it. Meanwhile, exploring the role of the tumor microenvironment (TME) in the development and metastasis of thoracic tumors can help us better understand the potential mechanisms of tumor spread and find approaches to intervene.

Innovations In Cardio Oncology

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Author : Sherry-Ann Brown
language : en
Publisher: Elsevier
Release Date : 2025-06-13

Innovations In Cardio Oncology written by Sherry-Ann Brown and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-13 with Science categories.

Innovations in Cardio-Oncology: Artificial Intelligence, Digital Health, and Precision Medicine reviews the benefits of biomedical technologies and advancements in individualized medicine, with applications in cardio-oncology.Illustrations of work involving machine learning and natural language processing help readers understand and maximize the benefits of artificial intelligence (AI) algorithms, with integration of AI and digital health technologies into the clinical workflow for personalized patient care, research, and provider and patient education.In 31 chapters, Innovations in Cardio-Oncology: Artificial Intelligence, Digital Health, and Precision Medicine introduces the emergent medical field at the interface of cardiology and oncology, "cardio-oncology", and describes prevention, screening and surveillance, followed by several chapters on the role of the applications of digital health, telemedicine, and AI in cardio-oncology precision care. The book also highlights many medical society guidelines and evidence-based recommended pathways for equitable digital health deployment and utilization in cardio-oncology care. This book anticipates that AI algorithms and innovative health tools have the potential to address, and does not have to widen, the already existing healthcare disparities, including inequalities related to race, ethnicity, gender, socioeconomic level, health insurance status, linguistic and cultural barriers, systemic discrimination, and healthcare access.This book provides valuable practical guidance for healthcare professionals, scientists, learners, and patients to integrate digital health platforms into their clinical practice, research, and patient engagement models, fit for individual use and also for multi-stakeholder groups from academia, technology, and industry, with shared interests in applying Innovation (Digital Health, mHealth, Telemedicine, Telehealth, Informatics, Precision Health, Computational Medicine, Social Media, Artificial Intelligence including Machine Learning, Deep Learning, Natural Language Processing, and Neural Networks, & more) to Cardiology and Oncology clinical practice, research, and education.• Addresses cardiovascular complications from cancer treatment with greater precision and individualization due to advances in personalized medicine, AI, including machine learning.• Presents successful methods and tools for preventing and managing cardiovascular disease in cancer patients.• Provides solidified practical best practices relating to innovation technologies and precision in Cardio-Oncology.• Includes insights and reports on various collaborative projects from the Cardiology Oncology Innovation Network (COIN) network members and colleagues, among a variety of other innovators, including applications of AI and informatics in Cardiology, Oncology, and especially Cardio-Oncology.

Handbook Of Translational Transcriptomics

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Author : Anton Buzdin
language : en
Publisher: Academic Press
Release Date : 2025-05-16

Handbook Of Translational Transcriptomics written by Anton Buzdin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-16 with Science categories.

Handbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview of the field of transcriptomics. With an emphasis on the various protocols and techniques available for investigation, it acts as a practical guide to researchers for implementing their own investigations in the field.This book begins with an overview of the past, present, and potential approaches in the field of transcriptomics, with discussions of choosing the correct approach based on the research needed. It also highlights the pros and cons of each approach. Following this, it explores techniques and protocols for investigating specific approaches focusing on RNA sequencing, expression arrays, and gene expression. It then delves into data analysis and offers recommendations, guidelines, and approaches related to data interpretation. This book also considers the translation of transcriptomics to clinical use and applications in molecular diagnostics, biomarkers in medicine, and personalized medicine specific to oncology, as well as biotechnology for pharmaceutical research.Handbook of Translational Transcriptomics: Research, Protocols and Applications is a detailed reference that provides a complete view of transcriptomics, ranging from methods to handling data and medical applications. This book is an invaluable guide for researchers working across molecular biology, genetics, bioinformatics and related fields, as well as graduate and PhD students in these areas. - Features practical guidance and protocols for researchers to replicate transcriptomic methods and techniques, including wet lab techniques. - Includes useful information on analyzing and interpreting transcriptomic data. - Offers a detailed introduction into translational transcriptomics, exploring both coding and noncoding RNAs including microRNA. - Investigates clinical implications of transcriptomics and applications to treating disease. - Considers some experimental and bioinformatic techniques in the field of transcriptomics, as well as more established approaches.

Innovations And Applications Of Advanced Biomaterials In Healthcare And Engineering

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Author : Al-Humairi, Safaa Najah Saud
language : en
Publisher: IGI Global
Release Date : 2025-04-25

Innovations And Applications Of Advanced Biomaterials In Healthcare And Engineering written by Al-Humairi, Safaa Najah Saud and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-25 with Technology & Engineering categories.

Biomaterials integrated into healthcare and engineering design, properties, and applications in modern science and technology advance current fabrication processes. With their biocompatibility, they enhance the performance of tissue engineering, medical implants, drug delivery systems, and other areas of technological advancement. Various categories of biomaterials may lead to innovations in smart materials and manufacturing. They may inspire innovative solutions to global challenges in healthcare and technology. Innovations and Applications of Advanced Biomaterials in Healthcare and Engineering serves as a consolidated resource, offering both foundational knowledge and advanced research insights with the latest developments in biomaterials. Case studies and real-world implementations complement theoretical insights, bridging the gap between academic research and practical innovation. Covering topics such as immunotherapy, multidrug resistance, and metalloptosis mechanisms, this book is an excellent resource for material scientists, biomedical engineers, clinicians, researchers, academicians, and more.

Cell Membrane Engineering For Advancing Cell Based And Nanotechnology Based Therapies

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Author : Zahid Hussain
language : en
Publisher: Springer Nature
Release Date : 2025-07-18

Cell Membrane Engineering For Advancing Cell Based And Nanotechnology Based Therapies written by Zahid Hussain and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-18 with Technology & Engineering categories.

The battle against complex diseases and tissue defects drives innovation in treatment and medical research. The cell membrane plays a fundamental role in biological processes and serves as a promising platform for diagnostic and therapeutic advancements due to its diverse receptors and ligands. Recent advances in bioengineering, synthetic biology, and biomimetic nanotechnology have enabled the development of engineered cell membrane-based platforms, including surface-engineered cells, extracellular vesicles, bacterial membrane vesicles, membrane-coated nanoparticles, and hybrid nanomaterials, offering improved therapeutic and diagnostic potential over their natural counterparts. This book provides a comprehensive exploration of essential cell surfaceome components, detailing state-of-the-art surface engineering strategies and advancements in engineered cells and membrane-based therapeutic nanoplatforms. It examines the transformative applications of these platforms in immune engineering, gastrointestinal disease management, cancer therapy, tissue engineering, circulating tumor cell capture, theranostics, and the treatment of neurodegenerative, inflammatory, and infectious diseases. Significant topics, many at the forefront of scientific research, are examined in depth, allowing academics, clinicians, and biomedical researchers to understand the latest advancements in cell membrane engineering and address unmet clinical needs. Furthermore, this interdisciplinary book is highly relevant to modern healthcare and provides instructional content for graduate students in chemical biology, pharmacology, biomaterials science, biomedical engineering, immune engineering, nanobiotechnology, regenerative medicine, and translational medicine. This book brings together pioneering research to inspire a broad scientific audience and drive innovation in disease monitoring, precision treatment, and biomedical applications.

Innovations In Healthcare And Outcome Measurement

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Author : Philipp Plugmann
language : en
Publisher: Springer Nature
Release Date : 2025-03-10

Innovations In Healthcare And Outcome Measurement written by Philipp Plugmann and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-10 with Medical categories.

Several innovations have revolutionized the healthcare sector in recent years. Digitalization, personalized medicine, Advanced Cell, and Tissue Engineering, and AI are some keywords associated with improving the prevention and therapy of diseases, i.e., to combat our crisis of non-communicable diseases. One of the key areas where innovation has had a profound impact is precision medicine. Precision medicine seeks to understand the unique genetic, environmental, and lifestyle factors contributing to an individual's health and disease risk. Through advancements in genomics, proteomics, and other molecular profiling techniques, healthcare providers can now gain a deeper understanding of a patient's molecular makeup. This knowledge allows for targeted interventions and therapies tailored to the specific needs of each individual, maximizing treatment efficacy and minimizing adverse effects. Furthermore, the development of advanced diagnostic tools has greatly enhanced the accuracy and efficiency of disease detection and monitoring. Innovations such as high-resolution imaging technologies, wearable sensors, and liquid biopsies have revolutionized the diagnostic landscape. Integrating artificial intelligence (AI) and machine learning (ML) algorithms has further augmented the capabilities of healthcare management and precision medicine capabilities. This book aims to bring up-to-date new ideas, opinions, development, and critical issues in healthcare and personalized medicine. We are interested in relevant articles covering a broad range of topics, such as: • Advances in medical devices • Digitalization and data-driven technologies • AI and algorithm-based drug development (molecule building, enhancement, clinical trials) • Diagnostic imaging • Personalized medicine • Nutrition • Oral health care • Healthcare management in certain diseases and population groups • Regulatory developments • Data management • Digital Healthcare Chapter "Unlocking the Code of Innovation: TRIZ Theory’s Blueprint for Precision Medicine Breakthroughs" is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/). For further details see licence information in the chapter.

Biomarker Detection Algorithms And Tools For Medical Imaging Or Omic Data

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Author : Fengfeng Zhou
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-13

Biomarker Detection Algorithms And Tools For Medical Imaging Or Omic Data written by Fengfeng Zhou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-13 with Science categories.