Application Of Biological Markers To Carcinogen Testing
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Application Of Biological Markers To Carcinogen Testing
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Author : Harry A. Milman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Application Of Biological Markers To Carcinogen Testing written by Harry A. Milman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Application Of Biological Markers To Carcinogen Testing
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Author : Harry A Milman
language : en
Publisher:
Release Date : 1983-11-01
Application Of Biological Markers To Carcinogen Testing written by Harry A Milman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-11-01 with categories.
Development And Application Of Biomarkers
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Author : Roger L. Lundblad
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Development And Application Of Biomarkers written by Roger L. Lundblad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
First introduced to biomedical research in 1980, the term biomarker has taken on a life of its own in recent years and has come to mean a number of things. In biomedical science, biomarker has evolved to most commonly mean a characteristic that can be used either as a diagnostic or a prognostic, but most significantly as a screening indicator for p
Biomarkers In Cancer Screening And Early Detection
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Author : Sudhir Srivastava
language : en
Publisher: John Wiley & Sons
Release Date : 2017-08-28
Biomarkers In Cancer Screening And Early Detection written by Sudhir Srivastava and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-28 with Medical categories.
Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment. Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers Provides immediately actionable information and hopefully also inspiration to move discovery and clinical application forward Offers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers
Novel Biomarkers For Potential Clinical Applications In Lung Cancer
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Author : Hongda Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2024-09-26
Novel Biomarkers For Potential Clinical Applications In Lung Cancer written by Hongda Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-26 with Medical categories.
More and more medical centers are now combining high-resolution CT scans well with deep learning and artificial intelligence for lung cancer screening, resulting in significantly improved diagnostic sensitivity. Furthermore, the increased molecular alterations in lung cancer were demonstrated not only in tumor tissue, but also in other body organs. For example, circulating tumor DNA combined with next-generation sequencing is now becoming a popular method for lung cancer diagnosis and therapeutic monitoring. Therefore, the first focus of this topic is on such achievements in early diagnosis of lung cancer, especially non-invasive tests such as liquid biopsy.
Developing Biomarker Based Tools For Cancer Screening Diagnosis And Treatment
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2006-11-18
Developing Biomarker Based Tools For Cancer Screening Diagnosis And Treatment written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-18 with Medical categories.
Research has long sought to identify biomarkers that could detect cancer at an early stage, or predict the optimal cancer therapy for specific patients. Fueling interest in this research are recent technological advances in genomics, proteomics, and metabolomics that can enable researchers to capture the molecular fingerprints of specific cancers and fine-tune their classification according to the molecular defects they harbor. The discovery and development of new markers of cancer could potentially improve cancer screening, diagnosis, and treatment. Given the potential impact cancer biomarkers could have on the cost effectiveness of cancer detection and treatment, they could profoundly alter the economic burden of cancer as well. Despite the promise of cancer biomarkers, few biomarker-based cancer tests have entered the market, and the translation of research findings on cancer biomarkers into clinically useful tests seems to be lagging. This is perhaps not surprising given the technical, financial, regulatory, and social challenges linked to the discovery, development, validation, and incorporation of biomarker tests into clinical practice. To explore those challenges and ways to overcome them, the National Cancer Policy Forum held the conference "Developing Biomarker-Based Tools for Cancer Screening, Diagnosis and Treatment: The State of the Science, Evaluation, Implementation, and Economics" in Washington, D.C., from March 20 to 22, 2006. At this conference, experts gave presentations in one of six sessions. In addition, seven small group discussions explored the policy implications surrounding biomarker development and adoption into clinical practice. Developing Biomarker-based Tools for Developing Cancer Screening, Diagnosis, and Treatment: The State of the Science, Evaluation, Implementation, and Economics-Workshop Summary presents the conference proceedings and will be used by an Institute of Medicine (IOM) committee to develop consensus-based recommendations for moving the field of cancer biomarkers forward.
Reducing Animal Use In Carcinogenicity Testing
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Author : Joseph Manuppello
language : en
Publisher: Frontiers Media SA
Release Date : 2024-12-31
Reducing Animal Use In Carcinogenicity Testing written by Joseph Manuppello and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-31 with Medical categories.
Carcinogenicity to rats and mice is evaluated for substances to which humans are exposed, including pharmaceuticals, agrochemicals, and industrial chemicals. For pharmaceuticals, recent efforts to reduce animal use in long-term studies include an addendum to the International Council for Harmonisation (ICH) guideline S1B(R1) that prioritizes short-term studies in transgenic mice and recommends assessing the weight of evidence available to first determine whether a long-term study in rats would add value. For other sectors, an expert group of the Organisation for Economic Cooperation and Development (OECD) is developing an Integrated Approach to the Testing and Assessment (IATA) of non-genotoxic carcinogens based on common hallmarks of cancers and on key characteristics of carcinogens. Within current regulations, animal use could be reduced by evaluating toxicokinetics in main study animals with microsampling methods, by including only one negative control group, and by genotyping transgenic mice instead of using positive control groups in each study.
Biomarkers In Toxicology
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Author : Ramesh C Gupta
language : en
Publisher: Academic Press
Release Date : 2019-02-13
Biomarkers In Toxicology written by Ramesh C Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-13 with Medical categories.
Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. - Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers - Includes completely revised chapters, along with additional chapters on the newest developments in the field - Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure - Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more
The Potential Of Cancer Biomarkers
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Author : Pranav Kumar Prabhakar
language : en
Publisher: Elsevier
Release Date : 2025-04-14
The Potential Of Cancer Biomarkers written by Pranav Kumar Prabhakar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-14 with Science categories.
The Potential of Biomarkers: From Discovery to Clinical Application addresses the challenges related to knowledge dissemination, interdisciplinary understanding, diagnostic complexity, quality assurance, patient care, research advancement, education, and professional development within the field of clinical biochemistry. The book provides a holistic solution by offering comprehensive insights and practical guidance to a diverse audience, contributing to the enhancement of healthcare and biomedical research. Each chapter explores the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.Cancer biomarkers, the molecular signatures of cancer, hold immense promise in revolutionizing how we diagnose, treat, and personalize therapies for cancer patients. In this curated reference, esteemed contributors explore the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more. - Presents the impact of biomarkers on early detection, prognosis, and personalized treatment strategies - Incudes ethical and regulatory considerations surrounding biomarker use, guiding policymakers and ethicists through the complex terrain of biomarker-driven healthcare decisions - Highlights the clinical relevance of cancer biomarkers by showcasing real-world case studies and examples of how biomarkers have been utilized to improve cancer diagnosis, personalize treatment plans, and monitor treatment responses
The Handbook Of Biomarkers
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Author : Kewal K. Jain
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-02-06
The Handbook Of Biomarkers written by Kewal K. Jain and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-06 with Medical categories.
Of the thousands of biomarkers that are currently being discovered, relatively few are being validated for further applications, and the potential of a biomarker can be quite difficult to evaluate. To aid in this imperative research, Dr. Kewal K. Jain’s Handbook of Biomarkers thoroughly describes many different types of biomarkers and their discovery using various "-omics" technologies, such as proteomics and metabolomics, along with the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials. With biomarkers described first according to technologies and then according to various diseases, this detailed book features the key correlations between diseases and classifications of biomarkers, which provides the reader with a guide to sort out current and future biomarkers. Comprehensive and cutting-edge, The Handbook of Biomarkers serves as a vital guide to furthering ourunderstanding of biomarkers, which, by facilitating the combination of therapeutics with diagnostics, promise to play an important role in the development of personalized medicine, one of the most important emerging trends in healthcare today.