Automated Retinal Layer Segmentation And Pre Apoptotic Monitoring For Three Dimensional Optical Coherence Tomography
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Automated Retinal Layer Segmentation And Pre Apoptotic Monitoring For Three Dimensional Optical Coherence Tomography
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Author : Vedran Kajic
language : en
Publisher:
Release Date : 2011
Automated Retinal Layer Segmentation And Pre Apoptotic Monitoring For Three Dimensional Optical Coherence Tomography written by Vedran Kajic and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
The aim of this PhD thesis was to develop segmentation algorithm adapted and optimized to retinal OCT data that will provide objective 3D layer thickness which might be used to improve diagnosis and monitoring of retinal pathologies. Additionally, a 3D stack registration method was produced by modifying an existing algorithm. A related project was to develop a pre-apoptotic retinal monitoring based on the changes in texture parameters of the OCT scans in order to enable treatment before the changes become irreversible; apoptosis refers to the programmed cell death that can occur in retinal tissue and lead to blindness. These issues can be critical for the examination of tissues within the central nervous system. A novel statistical model for segmentation has been created and successfully applied to a large data set. A broad range of future research possibilities into advanced pathologies has been created by the results obtained. A separate model has been created for choroid segmentation located deep in retina, as the appearance of choroid is very different from the top retinal layers. Choroid thickness and structure is an important index of various pathologies (diabetes etc.). As part of the pre-apoptotic monitoring project it was shown that an increase in proportion of apoptotic cells in vitro can be accurately quantified. Moreover, the data obtained indicates a similar increase in neuronal scatter in retinal explants following axotomy (removal of retinas from the eye), suggesting that UHR-OCT can be a novel non-invasive technique for the in vivo assessment of neuronal health. Additionally, an independent project within the computer science department in collaboration with the school of psychology has been successfully carried out, improving analysis of facial dynamics and behaviour transfer between individuals. Also, important improvements to a general signal processing algorithm, dynamic time warping (DTW), have been made, allowing potential application in a broad signal processing field.
Automated Three Dimensional Segmentation Of Intraretinal Layers From Optical Coherence Tomography Images Centered On The Optic Nerve Head
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Author : Bhavna Josephine Antony
language : en
Publisher:
Release Date : 2009
Automated Three Dimensional Segmentation Of Intraretinal Layers From Optical Coherence Tomography Images Centered On The Optic Nerve Head written by Bhavna Josephine Antony and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Automated 3 D Segmentation And Analysis Of Retinal Optical Coherence Tomography Images
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Author : Mona Kathryn Garvin
language : en
Publisher:
Release Date : 2008
Automated 3 D Segmentation And Analysis Of Retinal Optical Coherence Tomography Images written by Mona Kathryn Garvin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Optical coherence tomography categories.
High Resolution Imaging In Microscopy And Ophthalmology
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Author : Josef F. Bille
language : en
Publisher: Springer
Release Date : 2019-08-13
High Resolution Imaging In Microscopy And Ophthalmology written by Josef F. Bille and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-13 with Medical categories.
This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Clinical Applications Of Optical Coherence Tomography Angiography
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Author : Francesco Bandello
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2020
Clinical Applications Of Optical Coherence Tomography Angiography written by Francesco Bandello and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
"The recent introduction of optical coherence tomography angiography (OCTA) has remarkably expanded our knowledge of different retinal, chorioretinal, and optic disc disorders. OCTA is nowadays often introduced as a routine exam in clinical practice, granting the opportunity to non-invasively investigate retinal and choroidal circulation. In this book, many major experts in posterior eye imaging share their experiences and their latest images and ideas about OCTA"--
Fundus Autofluorescence
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Author : Noemi Lois
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2012-02-13
Fundus Autofluorescence written by Noemi Lois and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-13 with Medical categories.
Featuring over 250 illustrations, this detailed full-color textbook provides up-to-date information on the use of fundus autofluorescence imaging in evaluation of retinal disease. Chapters describe the techniques available to image and quantify fundus autofluorescence and the autofluorescence patterns observed in the healthy eye and in various retinal diseases. Emphasis is on the value of fundus autofluorescence as a diagnostic and prognostic tool and its clinical utility in the context of other imaging techniques, such as fluorescein and indocyanine green angiography and optical coherence tomography. Each chapter also discusses the value of fundus autofluorescence in understanding the pathogenesis of the condition, and provides a comprehensive update on all aspects of the condition. A companion Website will offer the fully searchable text and an image bank.
Fluorescence Lifetime Imaging Ophthalmoscopy
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Author : Martin Zinkernagel
language : en
Publisher: Springer
Release Date : 2019-07-29
Fluorescence Lifetime Imaging Ophthalmoscopy written by Martin Zinkernagel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-29 with Medical categories.
This book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.
Oct Atlas
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Author : Nagahisa Yoshimura
language : en
Publisher: Springer
Release Date : 2014-06-24
Oct Atlas written by Nagahisa Yoshimura and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-24 with Medical categories.
OCT provided a great advantage over other diagnostic modalities, as it could noninvasively provide tomographic images of the retina of a living eye. As a result, a number of new findings in retinal diseases were made using the time-domain OCT. OCT has now become an essential medical equipment OCT has now become an essential medical equipment in ophthalmic care and quality textbooks describing the functionality of OCT are very important in the education of young ophthalmologists and eye care personnel. In this book are chosen high quality OCT images of rather common diseases as well as images of several rare diseases.
Atlas Optical Coherence Tomography Of Macular Diseases And Glaucoma
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Author : Vishali Gupta
language : en
Publisher: JP Medical Ltd
Release Date : 2012-07-31
Atlas Optical Coherence Tomography Of Macular Diseases And Glaucoma written by Vishali Gupta and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-31 with Medical categories.
The fourth edition of this atlas has been completely updated to provide the latest thinking and technology developments in the use of OCT with macular diseases and glaucoma. Beginning with an introduction to OCT, the following section discusses its use with a range of conditions and disorders associated with macular diseases such as macular hole, foveal haemorrhage and retinal trauma. The final section examines the use of OCT for diagnosis and management of glaucoma. This new edition features more than 1300 illustrations including fundus photographs, fluorescein angiography and OCT images. Brief case studies are described and a new chapter on multimodal imaging has been included in this new edition. The bestselling previous edition published in 2010.
Oct And Imaging In Central Nervous System Diseases
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Author :
language : en
Publisher:
Release Date : 2020
Oct And Imaging In Central Nervous System Diseases written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Central nervous system categories.
The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson's disease, Alzheimer's disease, intracranial hypertension, Friedreich's ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the "window to the brain".