Autophagy And Inflammation In Neuropsychological Disorders

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Autophagy And Inflammation In Neuropsychological Disorders
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Author : Mokhtari, Tahmineh
language : en
Publisher: IGI Global
Release Date : 2025-07-16
Autophagy And Inflammation In Neuropsychological Disorders written by Mokhtari, Tahmineh and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-16 with Science categories.
In recent years, there has been considerable interest in the impact of inflammation on neuropsychological disorders, as it has the potential to significantly affect our psychiatric understanding and treatment approaches. Neuropsychological disorders encompass a wide range of conditions that affect the central nervous system, including neurodegenerative diseases, psychiatric disorders, and neurological conditions. While genetic, epigenetic, and environmental factors have been considered the main causes of these disorders, recent evidence suggests that inflammation and particularly some inflammation pathways might have a vital role in how they develop and progress. Autophagy and Inflammation in Neuropsychological Disorders presents the latest advancements in the field of inflammation and psychiatry, offering valuable insights for professionals in the field. By exploring the intersection of inflammation and psychiatry, readers can gain a deeper understanding of the subject and enhance their knowledge base. Covering topics such as post-ischemic conditions, nano-specific toxicity, and medical literacy, this book is an excellent resource for clinical practitioners, neurologists, psychologists, psychiatrists, professionals, researchers, scholars, academicians, and more.
Autophagy And Inflammation In Neuropsychological Disorders
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Author : Tahmineh Mokhtari
language : en
Publisher:
Release Date : 2025
Autophagy And Inflammation In Neuropsychological Disorders written by Tahmineh Mokhtari and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025 with Cell death categories.
"The primary objective of the book is to provide a comprehensive and up-to-date exploration of the interplay between autophagy and inflammation in the context of neuropsychological disorders. We welcome not only books directly focused on autophagy and inflammation but also topics associated with inflammation to enhance the breadth of our book and enhance our comprehension of the relationship between autophagy and inflammation"-- Provided by publisher.
Biomarkers Of Brain Injury And Neurological Disorders
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Author : Kevin K. W. Wang
language : en
Publisher: CRC Press
Release Date : 2014-10-28
Biomarkers Of Brain Injury And Neurological Disorders written by Kevin K. W. Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-28 with Medical categories.
This book explores the recent advances in the techniques and platforms used in biomarker research that have revolutionized the way we study, diagnose, and treat brain injury conditions. The contributors describe different biomarker studies pertaining to brain injury and other neurological disorders and analyze the different models and technologies
Epigenetic Regulation Of Autophagy In Inflammatory Diseases
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Author : Kai Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2024-03-13
Epigenetic Regulation Of Autophagy In Inflammatory Diseases written by Kai Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-13 with Medical categories.
Epigenetics refers to changes in the expression of heritable genes or cellular phenotypes caused by regulating DNA methylation, histone modification, chromatin remodeling, and noncoding RNA expression, without altering the DNA sequence. It plays a critical role in the regulation of many physiological and pathological processes, such as inflammation, immunity, and tumor. In particular, many epigenetic modifiers have been found to affect innate cell development, infection, and inflammatory responses by regulating gene-specific expression. Epigenetic abnormalities often result in changes in gene expression and its function, which in turn promote the process of inflammation and even tumorigenesis. Autophagy is a highly conserved subcellular degradation process by which some damaged organelles, misfolded proteins, nucleic acids, and pathogenic microorganisms are digested to maintain homeostasis. Autophagy dysregulation has been implicated in multiple diseases, including inflammation, tumors, and neurodegenerative diseases. It is not only a cytoplasmic event, but also involved in the regulation of nuclear components, including histone modifications, microRNA, and transcription factors. Methyltransferase-mediated histone modifications (H3K9me2, H3R17me2, and H3K27me3), miRNAs, and DNA methylation catalyzed by DNA methyltransferase are the key nuclear factors involved in the regulation of autophagy. In addition, some autophagy-related genes (Atgs) promote or inhibit the autophagic process through epigenetic modifications, such as histone modifications and DNA methylation, affecting the occurrence and development of inflammatory diseases. Studying the role of epigenetic regulation of autophagy in inflammatory diseases may help identify novel drug targets and develop potential diagnostic and therapeutic approaches. Although the biological and clinical significance of epigenetic modification of autophagy has attracted more and more attention from researchers, this regulation is very complex and its role and mechanism in inflammatory diseases are still unclear.
Rosenberg S Molecular And Genetic Basis Of Neurological And Psychiatric Disease Seventh Edition
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Author : Roger N. Rosenberg
language : en
Publisher: Elsevier
Release Date : 2024-10-04
Rosenberg S Molecular And Genetic Basis Of Neurological And Psychiatric Disease Seventh Edition written by Roger N. Rosenberg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-04 with Medical categories.
Rosenberg's Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Seventh Edition, provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to neurologic and psychiatric disease. This volume has been thoroughly revised and includes newly commissioned chapters on ethics, genetic counselling and genet therapy for the central nervous system disorders. A favorite of over four generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the previous edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community at large. - Both volumes combined provide a comprehensive coverage on the neurogenetic foundation of neurological and psychiatric disease - This volume provides a detailed introduction on both the clinical and basic research implications of molecular and genetics surrounding the brain - Includes new chapters on genomics of human neurological disorders, CRISPR and genome engineering
Neuroprotective Effects Of Phytochemicals In Neurological Disorders
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Author : Tahira Farooqui
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-20
Neuroprotective Effects Of Phytochemicals In Neurological Disorders written by Tahira Farooqui and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-20 with Medical categories.
Phytochemicals are naturally occurring bioactive compounds found in edible fruits, plants, vegetables, and herbs. Unlike vitamins and minerals, phytochemicals are not needed for the maintenance of cell viability, but they play a vital role in protecting neural cells from inflammation and oxidative stress associated with normal aging and acute and chronic age-related brain diseases. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the advances in our understanding of the potential neuroprotective benefits that these naturally occurring chemicals contain. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the role that a number of plant-based chemical compounds play in a wide variety of neurological disorders. Chapters explore the impact of phytochemicals on neurotraumatic disorders, such as stroke and spinal cord injury, alongside neurodegenerative diseases such as Alzheimer's and Parkinson's Disease, as well as neuropsychiatric disorders such as depression and schizophrenia. The chapters and sections of this book provide the reader with a big picture view of this field of research. Neuroprotective Effects of Phytochemicals in Neurological Disorders aims to present readers with a comprehensive and cutting edge look at the effects of phytochemicals on the brain and neurological disorders in a manner useful to researchers, neuroscientists, clinical nutritionists, and physicians.
Inflammation In Respiratory And Neurological Diseases And The Immune Interaction Of The Lung Brain Axis
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Author : Xiaohuan Xia
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-18
Inflammation In Respiratory And Neurological Diseases And The Immune Interaction Of The Lung Brain Axis written by Xiaohuan Xia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-18 with Medical categories.
Despite great advances in diagnosis and treatment that we witnessed in the last decades, over a billion people suffer from both respiratory and neurological diseases each year, which poses great threats to the public health and economic burden worldwide. In many instances, the underlying pathogenic mechanisms are still poorly understood, which significantly limits the efficacy of therapeutic methods. In this regard, lines of evidence pinpoint the important role of immunity and inflammation in both respiratory disorders (e.g., pulmonary hypertension, chronic obstructive pulmonary disease, asthma, etc.) and neurological ones (e.g., neurodegenerative diseases, stroke, depression, etc.). The accumulation of inflammatory cells and an excess of cytokines and chemokines at the inflammatory site would result from the disturbance of the body's delicate balance between immunity and tolerance. Therefore, it gives rise to chronic inflammation and autoimmunity underlying the development of both lung and neurological diseases. Furthermore, the inflammation interaction between lung and brain has been identified, suggesting the existence and importance of the lung-brain axis in the regulation of immune responses in the lung and brain that contribute to the onset and progression of both respiratory and neurological diseases. Nevertheless, inflammatory or immunity related risk factors as well novel targets and therapies against inflammation or immunity help early diagnosis and treatment of respiratory and neurological diseases. At present, the full picture of the molecular mechanisms of how immuno-inflammatory activation and the immune cells orchestrate the tissue remodeling leading to respiratory and neurological diseases remains unclear. The identification of inflammatory molecules as therapeutic targets or biomarkers are worth further scrutiny to halt the disease progression and monitor the therapeutic interventions.
Inflammation And Oxidative Stress In Neurological Disorders
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Author : Akhlaq A. Farooqui
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-01-27
Inflammation And Oxidative Stress In Neurological Disorders written by Akhlaq A. Farooqui and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-27 with Medical categories.
Unless new discoveries are made in the prevention or treatment of stroke, Alzheimer's Disease and depression, the number of patients with these diseases is sure to increase dramatically by the year 2050. Thus, developing strategies to retard or delay the onset of stroke, AD and depression these neurological disorders is of critical important. The present monograph will provide current and comprehensive information on the relationship between neuroinflammation and oxidative stress in age-related neurological disorders at the molecular level. The information described in this monograph on lifestyle (diet and exercise), genes and age is intended to facilitate and promote new discoveries for the treatment of age-related neurological disorders.
A Review On Diverse Neurological Disorders
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Author : Rameshwar Nath Chaurasia
language : en
Publisher: Elsevier
Release Date : 2024-06-05
A Review On Diverse Neurological Disorders written by Rameshwar Nath Chaurasia and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-05 with Medical categories.
According to World Health Organization (WHO) one billion people worldwide are affected by one of the thousands of neurological disorders, including epilepsy, Alzheimer disease, strokes, and headaches. Neurological disorders also include brain injuries, neuroinfections, multiple sclerosis and Parkinson disease. A Review on Neurological Disorders: Pathophysiology, Molecular Mechanisms, and Therapeutics covers the major topics related to neurological disorders, current challenges in diagnosis and intervention. This book is organized into four distinct sections, starting with an introduction, providing a general overview of the epidemiology of neurological disorders, pathogenesis and management. The second section presents the aspects of brain diseases due to infection of bacteria, parasite, fungus and viruses. The third section discusses neurodegenerative disorders due to comorbid factors like diabetes, hypertension, hyperlipidemia and post traumatic brain injuries. The last section covers prevention through application of bioactive compounds and neuroprotective agents. - Epidemiology of neurological disorders and pathogenesis. - Explores neuroinflammation, ligand-receptors binding, and neurodegeneration. - Discusses aging and associated disorders in the onset of neurological disorders. - Neuropharmacology and the protective role of bioactive compounds in neuroprotection.
The Role Of Gut Microbiota And Probiotics In Modulating Gut Brain Axis Of Humans And Animals
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Author : Hesong Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-29
The Role Of Gut Microbiota And Probiotics In Modulating Gut Brain Axis Of Humans And Animals written by Hesong Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-29 with Science categories.