Inflammation In Respiratory And Neurological Diseases And The Immune Interaction Of The Lung Brain Axis
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Inflammation In Respiratory And Neurological Diseases And The Immune Interaction Of The Lung Brain Axis
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Author : Xiaohuan Xia
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-18
Inflammation In Respiratory And Neurological Diseases And The Immune Interaction Of The Lung Brain Axis written by Xiaohuan Xia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-18 with Medical categories.
Despite great advances in diagnosis and treatment that we witnessed in the last decades, over a billion people suffer from both respiratory and neurological diseases each year, which poses great threats to the public health and economic burden worldwide. In many instances, the underlying pathogenic mechanisms are still poorly understood, which significantly limits the efficacy of therapeutic methods. In this regard, lines of evidence pinpoint the important role of immunity and inflammation in both respiratory disorders (e.g., pulmonary hypertension, chronic obstructive pulmonary disease, asthma, etc.) and neurological ones (e.g., neurodegenerative diseases, stroke, depression, etc.). The accumulation of inflammatory cells and an excess of cytokines and chemokines at the inflammatory site would result from the disturbance of the body's delicate balance between immunity and tolerance. Therefore, it gives rise to chronic inflammation and autoimmunity underlying the development of both lung and neurological diseases. Furthermore, the inflammation interaction between lung and brain has been identified, suggesting the existence and importance of the lung-brain axis in the regulation of immune responses in the lung and brain that contribute to the onset and progression of both respiratory and neurological diseases. Nevertheless, inflammatory or immunity related risk factors as well novel targets and therapies against inflammation or immunity help early diagnosis and treatment of respiratory and neurological diseases. At present, the full picture of the molecular mechanisms of how immuno-inflammatory activation and the immune cells orchestrate the tissue remodeling leading to respiratory and neurological diseases remains unclear. The identification of inflammatory molecules as therapeutic targets or biomarkers are worth further scrutiny to halt the disease progression and monitor the therapeutic interventions.
Lung Inflammation In Health And Disease Volume I
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Author : Yong-Xiao Wang
language : en
Publisher: Springer Nature
Release Date : 2021-03-31
Lung Inflammation In Health And Disease Volume I written by Yong-Xiao Wang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-31 with Medical categories.
Respiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from from respiratory infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for those affected. Current treatment options for lung disease are neither effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
Interactions Of The Gut Microbiota And The Innate Immune System
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Author : Daniel Erny
language : en
Publisher: Frontiers Media SA
Release Date : 2022-04-19
Interactions Of The Gut Microbiota And The Innate Immune System written by Daniel Erny and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-19 with Science categories.
Viral Parasitic Bacterial And Fungal Infections
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Author : Debasis Bagchi
language : en
Publisher: Academic Press
Release Date : 2022-10-15
Viral Parasitic Bacterial And Fungal Infections written by Debasis Bagchi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-15 with Medical categories.
Viral, Parasitic, Bacterial, and Fungal Infections: Antimicrobial, Host Defense, and Therapeutic Strategies highlight diverse types of infections, including viral, bacterial, parasitic, fungal, and the therapeutic efficacy of antibiotics, antivirals, antifungals and other medications, nutraceuticals, and phytotherapeutics. This book addresses the molecular, pathophysiological, and cellular pathways involved in the process of infection. It also examines the host defense mechanisms modulated by innate and adaptive immunity. The book starts off with an introduction, which includes etiology, pathophysiology, and diagnosis of infections. It then goes on to cover a wide spectrum of salient features involved in viral, bacterial, parasitic, and fungal infections and effective therapeutic strategies. In addition, there is a complete section of eight chapters elaborating the detailed aspects of COVID-19 infections, Mucormycosis, Omicron, and strategic vaccines and therapeutics. The book further goes on to discuss novel antibiotics, vaccines, bromhexine, boron compounds, phytotherapeutics, and aspects on boosting immune competence. Contributed by experts in the fields of viral, parasitic, bacterial, and fungal infections, the book comprehensively details the various types of infections such as herpes and COVID-19, their molecular mechanisms, and treatment strategies for those engaged in the research of infectious diseases. Details the pathophysiology of various classes of infections Examines mechanisms of pathogenesis, immunity, and therapeutics in bacterial, viral, and eukaryotic infectious diseases Discusses various aspects on herpes, COVID-19 infections, Mucormycosis, Omicron, vaccines, and therapeutics Covers the salient features on zoonosis, prion disease, and diabetic foot infections Provides therapeutic strategies of using new antibiotics, vaccines, bromhexine, boron compounds, structurally diverse phytotherapeutics, immune enhancers, and other modalities for treating infections
Pulmonary Infection And Inflammation
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Author : Mieczyslaw Pokorski
language : en
Publisher: Springer
Release Date : 2018-06-15
Pulmonary Infection And Inflammation written by Mieczyslaw Pokorski and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-15 with Medical categories.
Pulmonary diseases are the major cause of human morbidity, taxing the health care system due to disease prevalence, chronicity, and social and fiscal costs. This book concentrates on the inflammatory and immunogenic settings of pulmonary disorders and related medical areas. Excessive inflammation causes lung injury and forms a conducive background for pathogenic infections, particularly in immuno-compromised hosts. Bacterial immuno-evasive strategies develop, leading to self-perpetuating pathologies. Inflammation also is an essential component of non-communicable lung diseases, including asthma and respiratory allergies, and smoking-related or granulomatous diseases. The chapters combine a strong grounding in basic science with extensive clinical knowledge and experience. Advances in diagnostics, as well as preventive and therapeutic aspects also are tackled. The book provides useful information to clinicians, researchers, health care and other medical professionals.
The Lung Microbiome
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Author : Michael J. Cox
language : en
Publisher: European Respiratory Society
Release Date : 2019-03-01
The Lung Microbiome written by Michael J. Cox and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-01 with Medical categories.
Studying the lung microbiome requires a specialist approach to sampling, laboratory techniques and statistical analysis. This Monograph introduces the techniques used and discusses how respiratory sampling, 16S rRNA gene sequencing, metagenomics and the application of ecological theory can be used to examine the respiratory microbiome. It examines the different components of the respiratory microbiome: viruses and fungi in addition to the more frequently studied bacteria. It also considers a range of contexts from the paediatric microbiome and how this develops to disease of all ages including asthma and chronic obstructive pulmonary disease, chronic suppurative lung diseases, interstitial lung diseases, acquired pneumonias, transplantation, cancer and HIV, and the interaction of the respiratory microbiome and the environment.
Every Body Should Know This
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Author : Federica Amati
language : en
Publisher: Random House
Release Date : 2024-04-25
Every Body Should Know This written by Federica Amati and has been published by Random House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-25 with Health & Fitness categories.
***AS SEEN ON THIS MORNING*** DISCOVER THE SCIENCE OF EATING FOR A LIFETIME OF HEALTH ‘An essential nutrition and lifestyle guide across the lifespan. A fascinating DIY guide to food and health – read it!’ Dr Tim Spector, author of Spoon Fed and Food for Life ‘This book contains the most critical answers to nutrition that we’ve all been searching for. A must read’ Steven Bartlett 'Truly amazing and completely transformative’ Davina McCall ---- A SCIENCE-BACKED NUTRITION GUIDE FOR ALL LIFE STAGES In Every Body Should Know This, medical scientist and Head Nutritionist at ZOE, Dr Federica Amati explores the real science behind nutrition. By following her advice, you will learn how to eat for best health at each life stage and discover what every body should know, such as . . . - The truth surrounding superfoods and ultra-processed foods - Why nutrition plays a crucial role from before conception to senior years - How food choices can support longevity - Targeted tips for good health at each life stage With this book, you will gain insights into what foods work for the bodies and minds of you and your loved ones, and implement clear, nutritional strategies backed by the latest scientific research for men, women and children. Because when it comes to food, one size does not fit all. ---- 'A definitive guide on not just what to eat, but when and why' Daily Telegraph 'So good, so informative. There's so much incredible stuff in here' Cat Deeley and Ben Shepherd, This Morning ‘An easy to implement and practical guide to nutritional science!’ Dr Karan Rajan, author of This Book Will Save Your Life ‘Federica offers a novel framework for thinking about nutrition and points to the lifestyle factors that do make a difference in protecting and enhancing our long-term health. This is a book you shouldn’t miss’ Dr Sarah Berry
Research Grants Index
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Author : National Institutes of Health (U.S.). Division of Research Grants
language : en
Publisher:
Release Date : 1975
Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Medicine categories.
Problems Of Drug Dependence
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Author :
language : en
Publisher:
Release Date : 2001
Problems Of Drug Dependence written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Drug abuse categories.
Coronaviruses And Arteriviruses
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Author : Luis Enjuanes
language : en
Publisher: Springer Science & Business Media
Release Date : 1998-08-31
Coronaviruses And Arteriviruses written by Luis Enjuanes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-08-31 with Science categories.
Proceedings of the VIIth International Symposium held in Segovia, Spain, May 10-15, 1997