Bacterial Regulatory Networks
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Bacterial Regulatory Networks
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Author : Alain Filloux
language : en
Publisher: Caister Academic Press Limited
Release Date : 2012
Bacterial Regulatory Networks written by Alain Filloux and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Science categories.
Regulatory networks enable bacteria to adapt to almost every environmental niche on earth. Regulation is achieved by a network of interactions among diverse types of molecules including DNA, RNA, proteins and metabolites. The primary role of regulatory networks in bacteria is to control the response to environmental changes, such as nutritional status and environmental stress. A complex organization of networks allows the organism to coordinate and integrate multiple environmental signals. Renowned authors under the expert guidance of the editor Alain A.M. Filloux, have contributed authoritative, up-to-date reviews of the current research and theories on regulatory networks in bacteria. The volume contains critical reviews written by the leading research scientists in this topical field. The authors fully explore various regulatory networks, discuss variations of common themes and provide fresh insights into bacterial regulatory mechanisms. Topics include: the sigma network in Escherichia coli, control of bacterial virulence, ECF sigma factors, quorum sensing, cyclic di-GMP, RNA-mediated regulation, the H-NS regulator, two-component regulatory systems, bacterial chemotaxis, regulation of iron homeostasis, anaerobic regulatory networks, bacterial bistable regulatory networks, and evolution of transcription factors and regulatory networks. This book is essential reading for everyone interested in gene expression and regulation in bacteria and is a recommended text for all microbiology libraries.
Bacterial Regulatory Networks
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Author : Alain A. M. Filloux
language : en
Publisher:
Release Date : 2012
Bacterial Regulatory Networks written by Alain A. M. Filloux and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
Renowned authors under the expert guidance of the editor Alain A.M. Filloux, have contributed authoritative, up-to-date reviews of the current research and theories on regulatory networks in bacteria. The volume contains critical reviews written by the leading research scientists in this topical field. The authors fully explore various regulatory networks, discuss variations of common themes and provide fresh insights into bacterial regulatory mechanisms. Topics include: the sigma network in Escherichia coli, control of bacterial virulence, ECF sigma factors, quorum sensing, cyclic di-GMP, RNA.
Stress And Environmental Regulation Of Gene Expression And Adaptation In Bacteria
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Author : Frans J. de Bruijn
language : en
Publisher: John Wiley & Sons
Release Date : 2016-07-13
Stress And Environmental Regulation Of Gene Expression And Adaptation In Bacteria written by Frans J. de Bruijn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-13 with Science categories.
Bacteria in various habitats are subject to continuously changing environmental conditions, such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication, acid stress, nitrosative stress, cell envelope stress, heavy metal exposure, osmotic stress, and others. In order to survive, they have to respond to these conditions by adapting their physiology through sometimes drastic changes in gene expression. In addition they may adapt by changing their morphology, forming biofilms, fruiting bodies or spores, filaments, Viable But Not Culturable (VBNC) cells or moving away from stress compounds via chemotaxis. Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including (alternative) sigma factors, bi- or tri-component regulatory systems, small non-coding RNA’s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin systems, the stringent response, efflux pumps, alarmones, and modulation of the cell envelope or membranes, to name a few. Many regulatory elements are conserved in different bacteria; however there are endless variations on the theme and novel elements of gene regulation in bacteria inhabiting particular environments are constantly being discovered. Especially in (pathogenic) bacteria colonizing the human body a plethora of bacterial responses to innate stresses such as pH, reactive nitrogen and oxygen species and antibiotic stress are being described. An attempt is made to not only cover model systems but give a broad overview of the stress-responsive regulatory systems in a variety of bacteria, including medically important bacteria, where elucidation of certain aspects of these systems could lead to treatment strategies of the pathogens. Many of the regulatory systems being uncovered are specific, but there is also considerable “cross-talk” between different circuits. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria is a comprehensive two-volume work bringing together both review and original research articles on key topics in stress and environmental control of gene expression in bacteria. Volume One contains key overview chapters, as well as content on one/two/three component regulatory systems and stress responses, sigma factors and stress responses, small non-coding RNAs and stress responses, toxin-antitoxin systems and stress responses, stringent response to stress, responses to UV irradiation, SOS and double stranded systems repair systems and stress, adaptation to both oxidative and osmotic stress, and desiccation tolerance and drought stress. Volume Two covers heat shock responses, chaperonins and stress, cold shock responses, adaptation to acid stress, nitrosative stress, and envelope stress, as well as iron homeostasis, metal resistance, quorum sensing, chemotaxis and biofilm formation, and viable but not culturable (VBNC) cells. Covering the full breadth of current stress and environmental control of gene expression studies and expanding it towards future advances in the field, these two volumes are a one-stop reference for (non) medical molecular geneticists interested in gene regulation under stress.
Bacterial Gene Regulation And Transcriptional Networks
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Author : M. Madan Babu
language : en
Publisher:
Release Date : 2011
Bacterial Gene Regulation And Transcriptional Networks written by M. Madan Babu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Bacterial genetics categories.
Gene regulation at the transcriptional level is central to the process by which organisms convert the constant sensing of environmental changes and intracellular fluzes of metabolites to homeostatic responses. Along with the strategic guidance of M. Madan Babu authors from around the world have joined forces to review and discuss the latest research observations and current theories in this highly topical and important area of microbiology.
Bacterial Molecular Networks
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Author : Jacques van Helden
language : en
Publisher: Humana Press
Release Date : 2011-12-08
Bacterial Molecular Networks written by Jacques van Helden and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-08 with Science categories.
Network-based representations have become pervasive in most fields in biology. Bacterial Molecular Networks: Methods and Protocols provides authoritative descriptions of various experimental and computational methods enabling the characterization and analysis of molecular interaction networks, with a focus on bacteria. Divided into three convenient sections, this volume provides extensive coverage of various experimental and in silico approaches aiming at the characterization of network components, addresses the presentation of computational approaches to analyze the topology of molecular networks, and further introduces a variety of methods and tools enabling scientists to generate qualitative or quantitative dynamical models of molecular processes in bacteria. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Bacterial Molecular Networks: Methods and Protocols is intended primarily for post-graduate students and researchers working in the field of experimental and computational microbiology and provides a combination of up-to-date reviews along with detailed protocols written by the developers of bioinformatics resources, such as databases and software tools.
Bacterial Signal Transduction Networks And Drug Targets
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Author : Ryutaro Utsumi
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-05
Bacterial Signal Transduction Networks And Drug Targets written by Ryutaro Utsumi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-05 with Medical categories.
This fascinating book encourages many microbiologists and students to enter the new world of signal transduction in microbiology. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been unearthed.
The Physical Basis Of Bacterial Quorum Communication
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Author : Stephen J. Hagen
language : en
Publisher: Springer
Release Date : 2014-09-29
The Physical Basis Of Bacterial Quorum Communication written by Stephen J. Hagen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-29 with Science categories.
Quorum sensing (QS) describes a chemical communication behavior that is nearly universal among bacteria. Individual cells release a diffusible small molecule (an autoinducer) into their environment. A high concentration of this autoinducer serves as a signal of high population density, triggering new patterns of gene expression throughout the population. However QS is often much more complex than this simple census-taking behavior. Many QS bacteria produce and detect multiple autoinducers, which generate quorum signal cross talk with each other and with other bacterial species. QS gene regulatory networks respond to a range of physiological and environmental inputs in addition to autoinducer signals. While a host of individual QS systems have been characterized in great molecular and chemical detail, quorum communication raises many fundamental quantitative problems which are increasingly attracting the attention of physical scientists and mathematicians. Key questions include: What kinds of information can a bacterium gather about its environment through QS? What physical principles ultimately constrain the efficacy of diffusion-based communication? How do QS regulatory networks maximize information throughput while minimizing undesirable noise and cross talk? How does QS function in complex, spatially structured environments such as biofilms? Previous books and reviews have focused on the microbiology and biochemistry of QS. With contributions by leading scientists and mathematicians working in the field of physical biology, this volume examines the interplay of diffusion and signaling, collective and coupled dynamics of gene regulation, and spatiotemporal QS phenomena. Chapters will describe experimental studies of QS in natural and engineered or microfabricated bacterial environments, as well as modeling of QS on length scales spanning from the molecular to macroscopic. The book aims to educate physical scientists and quantitative-oriented biologists on the application of physics-based experiment and analysis, together with appropriate modeling, in the understanding and interpretation of the pervasive phenomenon of microbial quorum communication.
Bacterial Gene Regulation And Transcriptional Networks
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Author : M. Madan Babu
language : en
Publisher: Caister Academic Press Limited
Release Date : 2013
Bacterial Gene Regulation And Transcriptional Networks written by M. Madan Babu and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Science categories.
Gene regulation at the transcriptional level is central to the process by which organisms convert the constant sensing of environmental changes and intracellular fluzes of metabolites to homeostatic responses. Along with the strategic guidance of M. Madan Babu authors from around the world have joined forces to review and discuss the latest research observations and current theories in this highly topical and important area of microbiology.--
Global Regulatory Networks In Enteric Bacteria
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Author : Birgit M. Prüss
language : en
Publisher:
Release Date : 2005
Global Regulatory Networks In Enteric Bacteria written by Birgit M. Prüss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Bacterial genetics categories.
Prokaryotic Gene Expression
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Author : Simon Baumberg
language : en
Publisher: OUP Oxford
Release Date : 1999-05-27
Prokaryotic Gene Expression written by Simon Baumberg and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-05-27 with Science categories.
Prokaryotic gene expression is not only of theoretical interest but also of highly practical significance. It has implications for other biological problems, such as developmental biology and cancer, brings insights into genetic engineering and expression systems, and has consequences for important aspects of applied research. For example, the molecular basis of bacterial pathogenicity has implications for new antibiotics and in crop development. Prokaryotic Gene Expression is a major review of the subject, providing up-to-date coverage as well as numerous insights by the prestigious authors. Topics covered include operons; protein recognition of sequence specific DNA- and RNA-binding sites; promoters; sigma factors, and variant tRNA polymerases; repressors and activators; post-transcriptional control and attenuation; ribonuclease activity, mRNA stability, and translational repression; prokaryotic DNA topology, topoisomerases, and gene expression; regulatory networks, regulatory cascades and signal transduction; phosphotransfer reactions; switch systems, transcriptional and translational modulation, methylation, and recombination mechanisms; pathogenicity, toxin regulation and virulence determinants; sporulation and genetic regulation of antibiotic production; origins of regulatory molecules, selective pressures and evolution of prokaryotic regulatory mechanisms systems. Over 1100 references to the primary literature are cited. Prokaryotic Gene Expression is a comprehensive and authoritative review of current knowledge and research in the area. It is essential reading for postgraduates and researchers in the field. Advanced undergraduates in biochemistry, molecular biology, and microbiology will also find this book useful.