Bacterial Signaling
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Bacterial Signaling
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Author : Reinhard Krämer
language : en
Publisher: John Wiley & Sons
Release Date : 2009-12-09
Bacterial Signaling written by Reinhard Krämer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-09 with Science categories.
Providing a comprehensive insight into cellular signaling processes in bacteria with a special focus on biotechnological implications, this is the first book to cover intercellular as well as intracellular signaling and its relevance for biofilm formation, host pathogen interactions, symbiotic relationships, and photo- and chemotaxis. In addition, it deals in detail with principal bacterial signaling mechanisms -- making this a valuable resource for all advanced students in microbiology. Dr. Krämer is a world-renowned expert in intracellular signaling and its implications for biotechnology processes, while Dr. Jung is an expert on intercellular signaling and its relevance for biomedicine and agriculture.
Bacterial Signal Transduction Networks And Drug Targets
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Author : Ryutaro Utsumi
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-05
Bacterial Signal Transduction Networks And Drug Targets written by Ryutaro Utsumi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-05 with Medical categories.
This fascinating book encourages many microbiologists and students to enter the new world of signal transduction in microbiology. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been unearthed.
Bacterial Sensing And Signaling
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Author : Mattias Collin
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2009-01-01
Bacterial Sensing And Signaling written by Mattias Collin and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-01 with Medical categories.
Over the last fifteen years it has become increasingly obvious that bacteria are not as simple and solitary as once believed. Rather, an accumulating body of work shows that bacteria are highly complicated and social organisms, constantly sensing their surroundings and altering both their environments and behaviors to ensure survival. Direct communication between bacteria turns out to be quite common, as are coordinated intra- and interspecies responses that include the formation of highly sophisticated microbial communities. In fact, threats to bacterial survival from assaults ranging from nutrient deprivation and oxygen depletion tothe defenses of eukaryotic hostsare all managed through the integration of a dizzying array of complex sensory and communication systems with the appropriate bacterial behaviors. This volume provides an update of the current knowledgeinthe expanding field ofbacterial sensing and signaling, highlighting its most important and interesting aspects. In twelve state-of-the-art articles, respected international experts address topics such as quorum sensing and secondary messengers, chemotaxis and magnetoaerotaxis, two-component phosphotransferase systems, bacterial virulence mechanisms, thermoregulation, and more. The final chapter represents a unique description of the tools available to manipulate many of the sensing and signaling systems described in this volume. Bacterial Sensing and Signaling is recommended reading for students, scientists and clinicians with interests in microbiology, immunology, ecology, biotechnology and a range of other disciplines.
Bacterial Cell To Cell Communication
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Author : Donald R. Demuth
language : en
Publisher: Cambridge University Press
Release Date : 2006-02-23
Bacterial Cell To Cell Communication written by Donald R. Demuth and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-02-23 with Science categories.
Many bacterial diseases are caused by organisms growing together as communities or biofilms. These microorganisms have the capacity to coordinately regulate specific sets of genes by sensing and communicating amongst themselves utilizing a variety of signals. This book examines the mechanisms of quorum sensing and cell-to-cell communication in bacteria and the roles that these processes play in regulating virulence, bacterial interactions with host tissues, and microbial development. Recent studies suggest that microbial cell-to-cell communication plays an important role in the pathogenesis of a variety of disease processes. Furthermore, some bacterial signal molecules may possess immunomodulatory activity. Thus, understanding the mechanisms and outcomes of bacterial cell-to-cell communication has important implications for appreciating host-pathogen interactions and ultimately may provide new targets for antimicrobial therapies that block or interfere with these communication networks.
Cell Cell Signaling In Bacteria
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Author : Gary M. Dunny
language : en
Publisher:
Release Date : 1999
Cell Cell Signaling In Bacteria written by Gary M. Dunny and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Bacteria categories.
"This volume presents the first comprehensive review of bacterial quorum sensing, the signaling processes involved in control of multicellular activities of microbes. It reflects the explosion of knowledge in this area, and the realization that work being done in each of the signaling systems being studied may have important implications for other organisms not closely related by phylogeny or ecological niche."--BOOK JACKET.
Microbial Cyclic Di Nucleotide Signaling
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Author : Shan-Ho Chou
language : en
Publisher: Springer Nature
Release Date : 2020-03-05
Microbial Cyclic Di Nucleotide Signaling written by Shan-Ho Chou and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-05 with Science categories.
This book explores the broad and diverse biological and physiological impacts of established and newly discovered cyclic di-nucleotide second messenger signaling systems, while also providing descriptions of the intriguing biochemical characteristics of multiple turnover enzymes and receptors. The respective chapters discuss the commonalities and diversity of cyclic di-GMP, cyclic di-AMP and recently discovered cyclic GMP-AMP signaling systems in manifold Gram-negative and Gram-positive bacteria. The global human pathogens Mycobacterium tuberculosis, Vibrio cholerae, Salmonella typhimurium, Escherichia coli and Streptococcus pneumoniae, the facultative human pathogen Pseudomonas aeruginosa, global plant pathogens as exemplified by Xanthomonas campestris and Burkholderia spp., and the omnipresent probiotic Lactobacilli, as well as environmentally important photoautotrophic cyanobacteria, the multicellular Myxococcus xanthus, and chemolithotrophic Acidithiobacillus are among the representatives of the microbial kingdom that are described. In turn, the various aspects of bacterial physiology affected by these signaling systems– e.g. biofilm formation and dispersal, the cell cycle, motility, virulence, production of antimicrobials, fundamental metabolism and osmohomeostasis – are discussed in detail in the context of different microorganisms. Dedicated chapters focus on the population diversity of cyclic dinucleotide signaling systems, their tendency to be horizontally transferred, the cyclic di-GMP signaling system in the social amoeba Dictyostelium, honorary cyclic (di)nucleotides, and the development of strategies for interfering with cyclic dinucleotide signaling in order to manipulate microbial behavior. Taken together, the chapters provide an authoritative source of information for a broad readership: beginners and advanced researchers from various disciplines; individuals seeking a broad overview of cyclic di-nucleotide signaling; and those who want to learn more about specific aspects. Also featuring reviews with a forward-looking perspective, the book offers a valuable source of inspiration for future research directions.
Probing Bacterial Signaling And Cell Envelope Assembly With Chemical Reporters
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Author : Heather L. Hodges
language : en
Publisher:
Release Date : 2018
Probing Bacterial Signaling And Cell Envelope Assembly With Chemical Reporters written by Heather L. Hodges and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
The bacterial cell envelope is a dynamic structure that forms an essential barrier between the bacterial cytosol and the environment. This cell surface is comprised of species-specific lipids, glycans, enzymes and signaling pathways. Here, I exploited unique molecular building blocks of the mycobacterial cell envelope and molecules that can influence bacterial signaling pathways in E. coli to develop chemical reporters. First, I explored formation and signaling of the E. coli chemotaxis array, a pathway that is crucial for bacterial motility. We assessed how chemotaxis array architecture is altered by modulating the composition of the three core proteins that compose the chemotaxis array. We observed intriguing intermediates that reveal insights into array assembly and architecture (Chapter 2). Next, I developed of an analog of the chemotaxis ligand aspartate, which binds to a chemotaxis array receptor protein. Multivalent polymers functionalized with this aspartate analog are effective activators of chemotaxis signaling. The modular design of this synthetic polymer presents an opportunity to investigate how multifold engagement of chemotaxis receptors by polymers can affect signaling (Chapter 3). Additionally, I have developed small molecule probes to investigate the biosynthesis and dynamics of the mycobacterial cell envelope. This core, termed the mycolylarabinogalactan, is a lipoheteropolysaccharide critical to the survival of mycolated bacteria. In this work an analog of the donor monosaccharide for the arabinan was developed. This arabinan monosaccharide probe presents a scaffold to tailor the arabinan with reporter groups and represents a new delivery strategy to manipulate arabinan structure and investigate arabinan biosynthetic enzymes (Chapter 5). I also demonstrate the utility of a fluorogenic mimic of a trehalose glycolipid to localize activity of the enzymes that generate the mycolic acid portion of the mycobacterial cell wall during growth (Chapter 4). This probe functions in live cells to report on mycolic acid assembly in real time and revealed that mycolyltransferase activity was localized throughout the cell cycle. This probe was employed as a diagnostic to identify mycolic acid containing bacteria in mixtures of cells. This work builds a toolbox of novel glycolipid donor probes to provide access to mycobacterial cell wall biosynthesis.
Microbial Signalling And Communication
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Author : Society for General Microbiology. Symposium
language : en
Publisher: Cambridge University Press
Release Date : 1999-05-06
Microbial Signalling And Communication written by Society for General Microbiology. Symposium and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-05-06 with Medical categories.
Presents information at the forefront of this exciting field and includes contributions on a range of organisms and signalling molecules.
Trends In Quorum Sensing And Quorum Quenching
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Author : V. Ravishankar Rai
language : en
Publisher: CRC Press
Release Date : 2020-05-04
Trends In Quorum Sensing And Quorum Quenching written by V. Ravishankar Rai and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-04 with Science categories.
The book on Trends in Quorum Sensing and Quorum Quenching: New Perspectives and Applications focuses on the recent advances in the field of quorum sensing in bacteria and the novel strategies developed for quorum sensing inhibition. The topics covered are multidisciplinary and wide-ranging,and includes quorum sensing phenomenon in pathogenic bacteria, food spoilers, and agriculturally relevant bacteria. The applications of quorum sensing inhibitors such as small molecules, bioactives, natural compounds, and quorum quenching enzymes in controlling bacterial infections in clinical settings, agriculture and aquaculture are discussed. The potential use of quorum quenching enzymes for mitigating biofouling is also covered. Special focus is given to exploring quorum sensing inhibitors from microbes and flora inhabiting biodiversity rich regions including tropical rain forests and marine environments. Key features: Covers the fundamental aspects, the progress and challenges in the field of quorum sensing and quorum quenching Reviews quorum sensing in Gram-positive and Gram-negative bacteria of clinical, agricultural, and industrial relevance Discusses the application and future trends of quorum sensing inhibitors from lab to clinical and environmental settings Provides comprehensive coverage on molecular mechanisms in bacterial signaling
Modulation Of Macrophage Signaling Pathways During Bacterial Infections
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Author : Supriya Shukla
language : en
Publisher: Frontiers Media SA
Release Date : 2021-08-18
Modulation Of Macrophage Signaling Pathways During Bacterial Infections written by Supriya Shukla and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-18 with Science categories.