Basic Epithelial Ion Transport Principles And Function
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Basic Epithelial Ion Transport Principles And Function
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Author : Kirk L. Hamilton
language : en
Publisher: Springer Nature
Release Date : 2020-11-26
Basic Epithelial Ion Transport Principles And Function written by Kirk L. Hamilton and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-26 with Medical categories.
This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on basic fundamentals of epithelial transport physiology. There is a range of chapters dedicated to specific aspects of epithelial ion transport and cell function. Accordingly, the authors discuss techniques used to determine epithelial function, principles of epithelia transport, polarization of epithelial cells, mathematical modelling of epithelial ion transport, protein folding of ion channels, degradation epithelial ion channels, fundamentals of epithelial sodium, potassium and chloride transport, fundamentals of bicarbonate secretion, volume regulation, and microRNA regulation of epithelial channels and transporters. Given its scope, Volume 1 offers a valuable resource for physiology students, scientists and clinicians alike.
Ion Transport Across Epithelial Tissues And Disease
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Author : Kirk L. Hamilton
language : en
Publisher: Springer Nature
Release Date : 2020-12-12
Ion Transport Across Epithelial Tissues And Disease written by Kirk L. Hamilton and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-12 with Medical categories.
This book discusses the unique ion channels and transporters found within the epithelial tissues of various organs, including the kidney, intestine, pancreas and respiratory tract. Authors focus on demonstrating the crucial roles that each of these channels and transporters play in transepithelial ion and fluid transport across epithelia, as well as in maintaining homeostasis. It allows readers to gain an understanding of the fundamentals of ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the second of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on a wide array of epithelial tissues and the use of organoids to study epithelial function. Furthermore, clinical researchers and basic scientists from various fields provide a medical perspective on the physiology of a number of tissues and organs of the body including the pancreas, intestine, sweat glands, mammary gland, inner ear epithelia, retinal pigment epithelia of the eye, choroid plexus, and the ectodermal epithelia in dental enamel formation. This volume aims to ‘round out’ the reader’s journey from basic science to the laboratory bench and clinical management of molecular diseases, making Volume 2 a must-read for students and scientists in the field of physiology, as well as for clinicians.
Studies Of Epithelial Transporters And Ion Channels
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Author : Kirk L. Hamilton
language : en
Publisher: Springer Nature
Release Date : 2021-03-04
Studies Of Epithelial Transporters And Ion Channels written by Kirk L. Hamilton and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-04 with Medical categories.
This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of epithelial ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the third of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. The focus of this volume lies with different ion channel and transporter families. Additionally, this volume benefits from pharmaceutical contributors and their insights into recent pre-clinical drug discovery efforts and results from clinical trials. Overall, these chapters offer a more thorough coverage of individual epithelial ion channels and transporters from the 1st Edition, along with eleven new chapters. That makes Volume 3 an insightful contribution for physiology students, scientists and clinicians.
Ion Channels And Transporters Of Epithelia In Health And Disease
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Author : Kirk L. Hamilton
language : en
Publisher: Springer
Release Date : 2015-12-14
Ion Channels And Transporters Of Epithelia In Health And Disease written by Kirk L. Hamilton and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-14 with Medical categories.
This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.
Human Cerebrospinal Fluid And Cerebrovascular Barrier
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Author : Hiroshi Ishikawa
language : en
Publisher: Springer Nature
Release Date : 2025-05-13
Human Cerebrospinal Fluid And Cerebrovascular Barrier written by Hiroshi Ishikawa and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-13 with Science categories.
This book offers a basic understanding of the complex mechanisms that protect the brain from harmful substances while still allowing for essential functions such as nutrient transport and waste removal. It explores the blood-cerebrospinal fluid barrier (BCSFB) and the blood-brain barrier (BBB) in depth, focusing on the latest research, innovative techniques, and unique perspectives from researchers worldwide. The book also examines the clinical relevance of brain barrier dysfunction, with a particular focus on multiple sclerosis (MS) and the potential role of brain barriers in the development of MS, intricate relationship between brain barriers and infectious diseases and much more. With contributions from experts in neurobiology, microbiology, and biophysics, this book provides a multidisciplinary perspective. Extensive research has been conducted on the cerebrovascular or cerebrospinal fluid barrier function. The recent development of a functional epithelial cell line derived from a human choroid plexus papilloma has paved the way for an in vitro model of the choroid plexus, which has been instrumental in elucidating the interplay between infection, metabolism, physiological functions, and disease. This book is an effort by the Editors to raise public knowledge of the cerebrovascular and cerebrospinal fluid barriers. With broad coverage of topics in "Human Cerebrospinal Fluid and Cerebrovascular Barrier", it is ideal for researchers studying cerebrovascular or cerebrospinal fluid barrier interested in staying up to date on the latest developments. Healthcare providers and researchers working to develop new treatments for MS, infectious diseases of the central nervous system and other neurological disorders will also value this book. The book provides students of medicine, pharmacy, biology, and engineering with a comprehensive understanding of the structure and function of brain barriers. Those seeking a thorough introduction to the field will also find the book enjoyable.
Ion And Water Transport In Cell Death
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Author : Markus Ritter
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-25
Ion And Water Transport In Cell Death written by Markus Ritter and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-25 with Science categories.
Lung Diseases
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Author : Elvis Irusen
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-03-02
Lung Diseases written by Elvis Irusen and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-02 with Medical categories.
The developments in molecular medicine are transforming respiratory medicine. Leading clinicians and scientists in the world have brought their knowledge and experience in their contributions to this book. Clinicians and researchers will learn about the most recent advances in a variety of lung diseases that will better enable them to understand respiratory disorders. This treatise presents state of the art essays on airways disease, neoplastic diseases, and pediatric respiratory conditions. Additionally, aspects of immune regulation, respiratory infections, acute lung injury/ARDS, pulmonary edema, functional evaluation in respiratory disorders, and a variety of other conditions are also discussed. The book will be invaluable to clinicians who keep up with the current concepts, improve their diagnostic skills, and understand potential new therapeutic applications in lung diseases, while scientists can contemplate a plethora of new research avenues for exploration.
Rang Dale S Pharmacology
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Author : James M. Ritter
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-12-02
Rang Dale S Pharmacology written by James M. Ritter and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-02 with Medical categories.
For 25 years, Rang and Dale’s Pharmacology has delivered the core basic and clinical science information required by students and healthcare practitioners worldwide. Authors H. P. Rang, J. M. Ritter, R. J. Flower, and G. Henderson have ensured that the 8th Edition of this easy-to-read, comprehensive text continues the tradition of excellence with new coverage of drugs affecting the skin and new components online at studentconsult.com. Consult this title on your favorite e-reader. Get the essential pharmacology information you need from one authoritative source with an outstanding global reputation for excellence. Progress confidently through all relevant aspects of pharmacology, beginning with a molecular understanding of receptors and drug actions through clinical uses of key groups of drugs. Find important content quickly thanks to a color-coded layout that enables easy navigation and cross-referencing. Master difficult concepts with Key Points boxes, Clinical Uses boxes, and full-color illustrations throughout. Stay up to date with new information in the field, including an all-new chapter on drugs that affect the skin. Take advantage of new and unique features online, including 500+ chapter-specific multiple choice questions for immediate self-assessment. eBook version included! For the first time, you can access the entire book online or offline across all devices with the Student Consult eBook!
Medical Masterclass
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Author :
language : en
Publisher: Royal College of Physicians
Release Date : 2008
Medical Masterclass written by and has been published by Royal College of Physicians this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Encyclopedia Of Gastroenterology
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-11-06
Encyclopedia Of Gastroenterology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Science categories.
Encyclopedia of Gastroenterology, Second Edition, Four Volume Set provides a comprehensive and concise reference on all aspects of gastroenterology and hepatology, including the organs in the gastrointestinal system, their functions in health and disease, and strategies or procedures to resolve or prevent problems and disease. This concise, up-to-date information includes comprehensive sections on the impact of nutrition, gastrointestinal microbiota, lifestyle, commonly used drugs, and surgical procedures on health and disease. Since the first edition, attention to the roles of nutrition and gastrointestinal microorganisms (microbiota, formerly Microbiota) in health and disease has skyrocketed. In addition, an entirely new section on obesity and diabetes is included. Presents comprehensive coverage of every topic within gastroenterology Offers researchers a one-stop, fully-referenced resource to explore questions Includes teaching tools, multimedia and interactive elements Provides readers with multi-layered content and a media-rich learning resource for both instructors and students Covers hot new topics in GI health and disease, including new sections on stem cells, intestinal bacteria, obesity and intestinal microbiota