Basic Mutagenicity Tests
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Basic Mutagenicity Tests
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Author : David J. Kirkland
language : en
Publisher: Cambridge University Press
Release Date : 1990-08-31
Basic Mutagenicity Tests written by David J. Kirkland and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-08-31 with Medical categories.
A summary of the essential texts that must be performed on all new compounds before they can be registered for use in the UK.
Supplementary Mutagenicity Tests
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Author : David J. Kirkland
language : en
Publisher: Cambridge University Press
Release Date : 1993-11-11
Supplementary Mutagenicity Tests written by David J. Kirkland and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-11-11 with Medical categories.
Originally published in 1993, this volume describes a complementary selection of tests to those described in the companion volume Basic Mutagenicity Tests (Cambridge University Press, 1990). These supplementary tests were used to assess risks of in vitro mutagenicity in those instances where the basic tests were inconclusive. As such, these tests had an important role in the assessment of the safety of compounds, drugs and chemicals. These supplementary test and guidelines, originally drawn up by the United Kingdom Environmental Mutagen Society (UKEMS) were fully revised in this publication to take full account of different regulatory guidelines and scientific advances. This volume will be of value to anyone with aninterest in regulatory affairs, mutagenicity testing and the registration of chemical products in the UK and Europe.
Handbook Of Mutagenicity Test Procedures
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Author : B.J. Kilbey
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Handbook Of Mutagenicity Test Procedures written by B.J. Kilbey and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help. This Second Edition updates this information, providing: - a comprehensive bench guide - methods known to be reliable - a broad spectrum of approaches - tips to avoid pitfalls when using unfamiliar techniques - data from population records - safety aspects of mutagens and carcinogens - basic statistical concepts for experiment design This `on the bench' methodological text provides the necessary information for most of the common assays for genetic damage in use. The book includes methods which have been sufficiently used and tested to make their use reliable, but also presents methods which are not widely used at present, but which might prove most useful in screening for mutagenic effects.
Supplementary Mutagenicity Tests
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Author : United Kingdom Environmental Mutagen Society. Sub-Committee on Guidelines for Mutagenicity Testing
language : en
Publisher: Cambridge University Press
Release Date : 1993-11-11
Supplementary Mutagenicity Tests written by United Kingdom Environmental Mutagen Society. Sub-Committee on Guidelines for Mutagenicity Testing and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-11-11 with Medical categories.
Originally published in 1993, this volume describes supplementary tests used to assess risks of in vitro mutagenicity when basic safety tests were inconclusive.
Mutagenicity Testing
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Author : S. Venitt
language : en
Publisher:
Release Date : 1984
Mutagenicity Testing written by S. Venitt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Language Arts & Disciplines categories.
LABORATORY MANUAL. GENETIC TOXICOLOGY. BACTERIA. YEAST. FRUIT FLY. CULTURED MAMMALIAN CELLS. CYTOGENETIC TESTING. RODENTS. DOMINANT LETHAL TEST.
Basic And Applied Mutagenesis
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Author : A. Muhammed
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Basic And Applied Mutagenesis written by A. Muhammed and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The aim of the editors of this volume is to use basic and ap plied studies in the field of mutagenesis to approach a problem of especial concern. The problem is that of the usage of toxic chemi cals, particularly agricultural chemicals, in ever-increasing quan tities in those parts of the world that feed the most people. Agri cultural chemicals that are in use in Pakistan are emphasized here. These are the same chemicals that are in use throughout the develop ing world, although the quantities of the different types that are used may vary from country to country, and from region to region within countries. A number of these chemicals can no longer be sold in Europe or in the United States, and it is often difficult to iden tify a scientific reason as to why they are sold at all. It is ironic that toxic chemicals are used as a humanitarian device to rid the world of Pestilence and Famine -- two of the Horsemen of the Apocalypse. If we do not wish poisonous chemicals to become the fifth Horseman of the Apocalypse, then we must begin now to identify and regulate the large-scale usage of toxic sub stances everywhere.
Mutagenicity Assays And Applications
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Author : Ashutosh Kumar
language : en
Publisher: Academic Press
Release Date : 2017-09-26
Mutagenicity Assays And Applications written by Ashutosh Kumar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-26 with Science categories.
Mutagenicity: Assays and Applications presents an extensive examination of the detection, assessment and future of mutagenicity, particularly as it concerns human health and the environment. Chapters focused on specific types of mutagens or testing methods for their detection collectively explore the current state of human and environmental mutagenesis, future perspectives and regulatory needs. The test procedures for measuring mutagenicity, their advantages and limitations are described with practical and procedural detail, along with their presentation and data processing aspects. It is an essential reference covering the breadth and depth of the field of mutagenicity studies and regulation. By providing both important introductory material and practical assays and applications, this book is useful to graduate students, academic and industry researchers and regulators at various stages of their careers, leading to improved risk assessment and regulation. Presents an up-to-date and in-depth review of the current state of mutagenesis research Draws upon the combined experience and expertise of an international group of highly respected editors and chapter authors Provides an introduction to the concept of mutagenesis with particular consideration given to novel chemicals and materials
Statistical Evaluation Of Mutagenicity Test Data
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Author : David J. Kirkland
language : en
Publisher: Cambridge University Press
Release Date : 2008-01-03
Statistical Evaluation Of Mutagenicity Test Data written by David J. Kirkland and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-03 with Medical categories.
This rigorous and practical account of the interpretation of mutagenicity test data draws upon the expertise of toxicologists and statisticians. Chemicals, such as drugs, food additives and pesticides, all need careful screening to eliminate potentially mutagenic compounds.
Guidelines For The Testing Of Chemicals For Mutagenicity
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Author : Great Britain. Committee on Mutagenicity of Chemicals in Food, Consumer Products, and the Environment
language : en
Publisher:
Release Date : 1981
Guidelines For The Testing Of Chemicals For Mutagenicity written by Great Britain. Committee on Mutagenicity of Chemicals in Food, Consumer Products, and the Environment and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Chemical mutagenesis categories.
references
Chemical Mutagens
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Author : Alexander Hollaender
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chemical Mutagens written by Alexander Hollaender and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
As editor I want especially to thank Dr. Ernst Freese for helpful co operation in preparing these volumes, and to express my appreclatlOn to Drs. Kurt Hirschhorn and Marvin Legator, the other members of the editorial board. Alexander Hollaender January 1971 Preface The purpose of these volumes is to encourage the development and ap plication of testing and monitoring procedures to avert significant human exposure to mutagenic agents. The need for protection against exposure to possibly mutagenic chemicals is only now coming to be generally realized. The recently issued Report of the Secretary's Commission on Pesticides and Their Possible Effects on Health (the Mrak Report-U.S. Department of Health, Education and Welfare, December 1969) has made an important start. Its Panel on Mutagenicity recommends that all currently used pesticides be tested for mutagenicity in several recently developed and relatively simple systems. Whether recommendations such as these are actually put into effect will depend on convincing government, industry, and the public that the problem is important, that the proposed tests would be effective, and that they can be conducted at a cost that is not prohibitive. Why is it important to screen environmental agents for mutagenic activity? To those who will read this book, the answer is self-evident. The sine qua non of all that we value and all that we are is our genetic heritage.