Statistical Evaluation Of Mutagenicity Test Data
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Statistical Evaluation Of Mutagenicity Test Data
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Author : David J. Kirkland
language : en
Publisher: Cambridge University Press
Release Date : 2008-01-03
Statistical Evaluation Of Mutagenicity Test Data written by David J. Kirkland and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-03 with Medical categories.
This rigorous and practical account of the interpretation of mutagenicity test data draws upon the expertise of toxicologists and statisticians. Chemicals, such as drugs, food additives and pesticides, all need careful screening to eliminate potentially mutagenic compounds.
Statistical Evaluation Of Mutagenicity Test Data
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Author :
language : en
Publisher:
Release Date : 1989
Statistical Evaluation Of Mutagenicity Test Data written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Mutagenicity testing categories.
Statistical Methods In Toxicology
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Author : Ludwig Hothorn
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-08
Statistical Methods In Toxicology written by Ludwig Hothorn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Medical categories.
This book contains selected papers from a workshop on modern statistical methods in toxicology held during the EUROTOX '90 conference in Leipzig. The papers deal with the biostatistical evaluation of the commonly used toxicological assays, i.e. mutagenicity, long-term carcinogenicity, embryotoxicity and chronic toxicity assays. The biological background is considered in detail, and most of the related statistical approaches described. In five overview papers, the present state of the art of the related topics is given, while in several contributed papers new approaches are discussed. The most important features are: - A new view on the per-litter analysis problem in em- bryotoxicity assays. - A highly sophisticated treatment of the so-called muta-tox problem in mutagenicity assays. - A detailed discussion of the multiplicity problem based on the closed testing procedure. This volume provides readers with an overview of modern biostatistical methods for several toxicological assays and is in part intended for direct, practical use.
A Nonparametric Approach To The Statistical Analysis Of Mutagenicity Data
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Author : Garry A. T. Mahon
language : de
Publisher:
Release Date : 1984
A Nonparametric Approach To The Statistical Analysis Of Mutagenicity Data written by Garry A. T. Mahon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with categories.
A Nonparametric Approach To The Statistical Analysis Of Mutagenicity Data
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Author : Garry A. Mahon
language : en
Publisher:
Release Date : 1984
A Nonparametric Approach To The Statistical Analysis Of Mutagenicity Data written by Garry A. Mahon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with categories.
Handbook Of Mutagenicity Test Procedures
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Author : B.J. Kilbey
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Handbook Of Mutagenicity Test Procedures written by B.J. Kilbey and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help. This Second Edition updates this information, providing: - a comprehensive bench guide - methods known to be reliable - a broad spectrum of approaches - tips to avoid pitfalls when using unfamiliar techniques - data from population records - safety aspects of mutagens and carcinogens - basic statistical concepts for experiment design This `on the bench' methodological text provides the necessary information for most of the common assays for genetic damage in use. The book includes methods which have been sufficiently used and tested to make their use reliable, but also presents methods which are not widely used at present, but which might prove most useful in screening for mutagenic effects.
Mutagenicity In The Dpi 3 Hgprt Marker Mammalian Cell Systems
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Author : Hong-Lin Su
language : en
Publisher:
Release Date : 1981
Mutagenicity In The Dpi 3 Hgprt Marker Mammalian Cell Systems written by Hong-Lin Su and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with categories.
Statistics And Experimental Design For Toxicologists And Pharmacologists Fourth Edition
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Author : Shayne C. Gad
language : en
Publisher: CRC Press
Release Date : 2005-07-18
Statistics And Experimental Design For Toxicologists And Pharmacologists Fourth Edition written by Shayne C. Gad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-07-18 with Medical categories.
Purposefully designed as a resource for practicing and student toxicologists, Statistics and Experimental Design for Toxicologists and Pharmacologists, Fourth Edition equips you for the regular statistical analysis of experimental data. Starting with the assumption of basic mathematical skills and knowledge, the author supplies a complete and systematic yet practical introduction to the statistical methodologists available for, and used in, the discipline. For every technique presented, a worked example from toxicology is also presented. See what's new in the Fourth Edition: The first practical guide to performing meta analysis allowing for using the power inherent in multiple similar studies Coverage of Bayesian analysis and data analysis in pharmacology and toxicology Almost 200 problems with solutions Discussion of analysis of receptor binding assays, safety pharmacology assays and other standard types conducted in pharmacology A new chapter explaining the basics of Good Laboratory Practices (GLPs) For those with computer skills, this edition has been enhanced with the addition of basic SAS Written specifically for toxicologists and pharmacologists, the author draws on more than 30 years of experience to provide understanding of the philosophical underpinnings for the overall structure of analysis. The book's organization fosters the ordered development of skills and yet still facilitates ease of access to information as needed. This Fourth Edition gives you the tools necessary to perform rigorous and critical analysis of experimental data and the insight to know when to use them.
Basic Mutagenicity Tests
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Author : David J. Kirkland
language : en
Publisher: Cambridge University Press
Release Date : 1990-08-31
Basic Mutagenicity Tests written by David J. Kirkland and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-08-31 with Medical categories.
A summary of the essential texts that must be performed on all new compounds before they can be registered for use in the UK.
Statistical Analysis Of Toxicological Experiments On Carcinogenicity Mutagenicity And Developmental Toxicity
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Author : D. Krewski
language : en
Publisher:
Release Date : 1996
Statistical Analysis Of Toxicological Experiments On Carcinogenicity Mutagenicity And Developmental Toxicity written by D. Krewski and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.