Bayesian Approaches In Oncology Using R And Openbugs

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Bayesian Approaches In Oncology Using R And Openbugs

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Author : Atanu Bhattacharjee
language : en
Publisher: CRC Press
Release Date : 2020-12-14

Bayesian Approaches In Oncology Using R And Openbugs written by Atanu Bhattacharjee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-14 with Mathematics categories.

Bayesian Approaches in Oncology Using R and OpenBUGS serves two audiences: those who are familiar with the theory and applications of bayesian approach and wish to learn or enhance their skills in R and OpenBUGS, and those who are enrolled in R and OpenBUGS-based course for bayesian approach implementation. For those who have never used R/OpenBUGS, the book begins with a self-contained introduction to R that lays the foundation for later chapters. Many books on the bayesian approach and the statistical analysis are advanced, and many are theoretical. While most of them do cover the objective, the fact remains that data analysis can not be performed without actually doing it, and this means using dedicated statistical software. There are several software packages, all with their specific objective. Finally, all packages are free to use, are versatile with problem-solving, and are interactive with R and OpenBUGS. This book continues to cover a range of techniques related to oncology that grow in statistical analysis. It intended to make a single source of information on Bayesian statistical methodology for oncology research to cover several dimensions of statistical analysis. The book explains data analysis using real examples and includes all the R and OpenBUGS codes necessary to reproduce the analyses. The idea is to overall extending the Bayesian approach in oncology practice. It presents four sections to the statistical application framework: Bayesian in Clinical Research and Sample Size Calcuation Bayesian in Time-to-Event Data Analysis Bayesian in Longitudinal Data Analysis Bayesian in Diagnostics Test Statistics This book is intended as a first course in bayesian biostatistics for oncology students. An oncologist can find useful guidance for implementing bayesian in research work. It serves as a practical guide and an excellent resource for learning the theory and practice of bayesian methods for the applied statistician, biostatistician, and data scientist.

Bayesian Approaches In Oncology Using R And Openbugs

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Author : Atanu Bhattacharjee
language : en
Publisher: CRC Press
Release Date : 2020-12-21

Bayesian Approaches In Oncology Using R And Openbugs written by Atanu Bhattacharjee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-21 with Mathematics categories.

Bayesian Approaches in Oncology Using R and OpenBUGS serves two audiences: those who are familiar with the theory and applications of bayesian approach and wish to learn or enhance their skills in R and OpenBUGS, and those who are enrolled in R and OpenBUGS-based course for bayesian approach implementation. For those who have never used R/OpenBUGS, the book begins with a self-contained introduction to R that lays the foundation for later chapters. Many books on the bayesian approach and the statistical analysis are advanced, and many are theoretical. While most of them do cover the objective, the fact remains that data analysis can not be performed without actually doing it, and this means using dedicated statistical software. There are several software packages, all with their specific objective. Finally, all packages are free to use, are versatile with problem-solving, and are interactive with R and OpenBUGS. This book continues to cover a range of techniques related to oncology that grow in statistical analysis. It intended to make a single source of information on Bayesian statistical methodology for oncology research to cover several dimensions of statistical analysis. The book explains data analysis using real examples and includes all the R and OpenBUGS codes necessary to reproduce the analyses. The idea is to overall extending the Bayesian approach in oncology practice. It presents four sections to the statistical application framework: Bayesian in Clinical Research and Sample Size Calcuation Bayesian in Time-to-Event Data Analysis Bayesian in Longitudinal Data Analysis Bayesian in Diagnostics Test Statistics This book is intended as a first course in bayesian biostatistics for oncology students. An oncologist can find useful guidance for implementing bayesian in research work. It serves as a practical guide and an excellent resource for learning the theory and practice of bayesian methods for the applied statistician, biostatistician, and data scientist.

Applied Bayesian Statistics

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Author : Mary Kathryn Cowles
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-01-04

Applied Bayesian Statistics written by Mary Kathryn Cowles and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-04 with Mathematics categories.

This book is based on over a dozen years teaching a Bayesian Statistics course. The material presented here has been used by students of different levels and disciplines, including advanced undergraduates studying Mathematics and Statistics and students in graduate programs in Statistics, Biostatistics, Engineering, Economics, Marketing, Pharmacy, and Psychology. The goal of the book is to impart the basics of designing and carrying out Bayesian analyses, and interpreting and communicating the results. In addition, readers will learn to use the predominant software for Bayesian model-fitting, R and OpenBUGS. The practical approach this book takes will help students of all levels to build understanding of the concepts and procedures required to answer real questions by performing Bayesian analysis of real data. Topics covered include comparing and contrasting Bayesian and classical methods, specifying hierarchical models, and assessing Markov chain Monte Carlo output. Kate Cowles taught Suzuki piano for many years before going to graduate school in Biostatistics. Her research areas are Bayesian and computational statistics, with application to environmental science. She is on the faculty of Statistics at The University of Iowa.

Reviews In Surgical Oncology

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Author : Cesare Ruffolo
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-14

Reviews In Surgical Oncology written by Cesare Ruffolo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-14 with Medical categories.

Big Data Analytics In Oncology With R

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Author : Atanu Bhattacharjee
language : en
Publisher: CRC Press
Release Date : 2022-12-29

Big Data Analytics In Oncology With R written by Atanu Bhattacharjee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-29 with Mathematics categories.

Big Data Analytics in Oncology with R serves the analytical approaches for big data analysis. There is huge progressed in advanced computation with R. But there are several technical challenges faced to work with big data. These challenges are with computational aspect and work with fastest way to get computational results. Clinical decision through genomic information and survival outcomes are now unavoidable in cutting-edge oncology research. This book is intended to provide a comprehensive text to work with some recent development in the area. Features: Covers gene expression data analysis using R and survival analysis using R Includes bayesian in survival-gene expression analysis Discusses competing-gene expression analysis using R Covers Bayesian on survival with omics data This book is aimed primarily at graduates and researchers studying survival analysis or statistical methods in genetics.

Bayesian Analysis With R For Drug Development

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Author : Harry Yang
language : en
Publisher: CRC Press
Release Date : 2019-06-26

Bayesian Analysis With R For Drug Development written by Harry Yang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-26 with Mathematics categories.

Drug development is an iterative process. The recent publications of regulatory guidelines further entail a lifecycle approach. Blending data from disparate sources, the Bayesian approach provides a flexible framework for drug development. Despite its advantages, the uptake of Bayesian methodologies is lagging behind in the field of pharmaceutical development. Written specifically for pharmaceutical practitioners, Bayesian Analysis with R for Drug Development: Concepts, Algorithms, and Case Studies, describes a wide range of Bayesian applications to problems throughout pre-clinical, clinical, and Chemistry, Manufacturing, and Control (CMC) development. Authored by two seasoned statisticians in the pharmaceutical industry, the book provides detailed Bayesian solutions to a broad array of pharmaceutical problems. Features Provides a single source of information on Bayesian statistics for drug development Covers a wide spectrum of pre-clinical, clinical, and CMC topics Demonstrates proper Bayesian applications using real-life examples Includes easy-to-follow R code with Bayesian Markov Chain Monte Carlo performed in both JAGS and Stan Bayesian software platforms Offers sufficient background for each problem and detailed description of solutions suitable for practitioners with limited Bayesian knowledge Harry Yang, Ph.D., is Senior Director and Head of Statistical Sciences at AstraZeneca. He has 24 years of experience across all aspects of drug research and development and extensive global regulatory experiences. He has published 6 statistical books, 15 book chapters, and over 90 peer-reviewed papers on diverse scientific and statistical subjects, including 15 joint statistical works with Dr. Novick. He is a frequent invited speaker at national and international conferences. He also developed statistical courses and conducted training at the FDA and USP as well as Peking University. Steven Novick, Ph.D., is Director of Statistical Sciences at AstraZeneca. He has extensively contributed statistical methods to the biopharmaceutical literature. Novick is a skilled Bayesian computer programmer and is frequently invited to speak at conferences, having developed and taught courses in several areas, including drug-combination analysis and Bayesian methods in clinical areas. Novick served on IPAC-RS and has chaired several national statistical conferences.

Bayesian Essentials With R

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Author : Jean-Michel Marin
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-28

Bayesian Essentials With R written by Jean-Michel Marin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-28 with Computers categories.

This Bayesian modeling book provides a self-contained entry to computational Bayesian statistics. Focusing on the most standard statistical models and backed up by real datasets and an all-inclusive R (CRAN) package called bayess, the book provides an operational methodology for conducting Bayesian inference, rather than focusing on its theoretical and philosophical justifications. Readers are empowered to participate in the real-life data analysis situations depicted here from the beginning. Special attention is paid to the derivation of prior distributions in each case and specific reference solutions are given for each of the models. Similarly, computational details are worked out to lead the reader towards an effective programming of the methods given in the book. In particular, all R codes are discussed with enough detail to make them readily understandable and expandable. Bayesian Essentials with R can be used as a textbook at both undergraduate and graduate levels. It is particularly useful with students in professional degree programs and scientists to analyze data the Bayesian way. The text will also enhance introductory courses on Bayesian statistics. Prerequisites for the book are an undergraduate background in probability and statistics, if not in Bayesian statistics.

Let The Evidence Speak

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Author : Alan Jessop
language : en
Publisher: Springer
Release Date : 2018-05-31

Let The Evidence Speak written by Alan Jessop and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-31 with Mathematics categories.

This book presents the most important ideas behind Bayes’ Rule in a form suitable for the general reader. It is written without formulae because they are not necessary; the ability to add and multiply is all that is needed. As well as showing in full the application of Bayes’ Rule to some quantitatively simple, though not trivial, examples, the book also convincingly demonstrates that some familiarity with Bayes’ Rule is helpful in thinking about how best to structure one’s thinking.

Bayesian Hierarchical Models

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Author : Peter D. Congdon
language : en
Publisher: CRC Press
Release Date : 2019-09-16

Bayesian Hierarchical Models written by Peter D. Congdon and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-16 with Mathematics categories.

An intermediate-level treatment of Bayesian hierarchical models and their applications, this book demonstrates the advantages of a Bayesian approach to data sets involving inferences for collections of related units or variables, and in methods where parameters can be treated as random collections. Through illustrative data analysis and attention to statistical computing, this book facilitates practical implementation of Bayesian hierarchical methods. The new edition is a revision of the book Applied Bayesian Hierarchical Methods. It maintains a focus on applied modelling and data analysis, but now using entirely R-based Bayesian computing options. It has been updated with a new chapter on regression for causal effects, and one on computing options and strategies. This latter chapter is particularly important, due to recent advances in Bayesian computing and estimation, including the development of rjags and rstan. It also features updates throughout with new examples. The examples exploit and illustrate the broader advantages of the R computing environment, while allowing readers to explore alternative likelihood assumptions, regression structures, and assumptions on prior densities. Features: Provides a comprehensive and accessible overview of applied Bayesian hierarchical modelling Includes many real data examples to illustrate different modelling topics R code (based on rjags, jagsUI, R2OpenBUGS, and rstan) is integrated into the book, emphasizing implementation Software options and coding principles are introduced in new chapter on computing Programs and data sets available on the book’s website

Bayesian Methods In Pharmaceutical Research

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Author : Emmanuel Lesaffre
language : en
Publisher: CRC Press
Release Date : 2020-04-15

Bayesian Methods In Pharmaceutical Research written by Emmanuel Lesaffre and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-15 with Medical categories.

Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages of the research, development, manufacturing, and health economic evaluation of new health care interventions. In 2010, the first Applied Bayesian Biostatistics conference was held, with the primary objective to stimulate the practical implementation of Bayesian statistics, and to promote the added-value for accelerating the discovery and the delivery of new cures to patients. This book is a synthesis of the conferences and debates, providing an overview of Bayesian methods applied to nearly all stages of research and development, from early discovery to portfolio management. It highlights the value associated with sharing a vision with the regulatory authorities, academia, and pharmaceutical industry, with a view to setting up a common strategy for the appropriate use of Bayesian statistics for the benefit of patients. The book covers: Theory, methods, applications, and computing Bayesian biostatistics for clinical innovative designs Adding value with Real World Evidence Opportunities for rare, orphan diseases, and pediatric development Applied Bayesian biostatistics in manufacturing Decision making and Portfolio management Regulatory perspective and public health policies Statisticians and data scientists involved in the research, development, and approval of new cures will be inspired by the possible applications of Bayesian methods covered in the book. The methods, applications, and computational guidance will enable the reader to apply Bayesian methods in their own pharmaceutical research.