Biochemical Modulation Of Skin Reactions


Biochemical Modulation Of Skin Reactions
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Biochemical Modulation Of Skin Reactions


Biochemical Modulation Of Skin Reactions
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Author : Agis F. Kydonieus
language : en
Publisher: CRC Press
Release Date : 1999-12-15

Biochemical Modulation Of Skin Reactions written by Agis F. Kydonieus and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-12-15 with Medical categories.


Like almost every major scientific or medical breakthrough in history, the transdermal delivery of drugs started as only an idea - slowly moving its way from the drawing board to actual testing and eventually approval. Today, there are more than 20 companies involved in transdermal drug delivery. In addition, almost every large pharmaceutical firm has ongoing transdermal delivery programs. But in spite of this effort and after 15 years from the introduction of the Nitroglycerin patch, only six transdermal drugs exist in the marketplace. The practice has been hampered by the fact that most drugs, as well as many excipients used in the manufacture of transdermal patches, cause skin irritation or skin sensitization. Similar problems exist with the application of dermatologicals and cosmetics to skin, which in many cases are equally as severe as those encountered in transdermal delivery. Biochemical Modulation of Skin Reactions: Transdermals, Topicals, Cosmetics presents a series of chapters describing technologies and the practical application of biochemicals which might lead to the reduction or abrogation of these skin reaction. In addition, it addresses those areas of skin immunology and skin sciences that account for the processes that control irritant and allergic contact dermatitis and outlines the numerous cellular and molecular factors involved in the development of irritation and sensitization. Indeed, Biochemical Modulation of Skin Reactions helps serve as a catalyst for further research in the field, allowing for more drugs and cosmetics to be applied to the skin without adverse effects. Features



Dermal Absorption


Dermal Absorption
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Author : J. Kielhorn
language : en
Publisher: World Health Organization
Release Date : 2006

Dermal Absorption written by J. Kielhorn and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.


Introduction and definitions -- Skin structure and function -- Skin transport mechanisms and theoretical concepts -- Metabolism in the skin -- In vitro tests for dermal absorption -- In vivo tests for dermal absorption -- Comparative studies -- Data collections -- Estimation/prediction of dermal penetration -- Use of dermal penetration studies in risk assessment -- Controversial topics in the assessment of dermal absorption -- Conclusions and recommendations.



Alternative Toxicological Methods


Alternative Toxicological Methods
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Author : Harry Salem
language : en
Publisher: CRC Press
Release Date : 2003-03-26

Alternative Toxicological Methods written by Harry Salem and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-26 with Medical categories.


Bringing together the recent and relevant contributions of over 125 scientists from industry, government, and academia in North America and Western Europe, Alternative Toxicological Methods explores the development and validation of replacement, reduction, and refinement alternatives (the 3Rs) to animal testing. Internationally recognized scientist



Allergic Contact Dermatitis


Allergic Contact Dermatitis
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Author : Camilla Smith
language : en
Publisher: CRC Press
Release Date : 2023-01-06

Allergic Contact Dermatitis written by Camilla Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-06 with Medical categories.


llergic Contact Dermatitis assesses the potential effects of xenobiotic metabolism and protein reactivity on toxicity. It reviews current knowledge of percutaneous absorption and skin metabolism and includes discussion of the xenobiotics themselves. It answers questions such as: How does sensitisation relate to protein reactivity and levels of metabolism? How we can identify potential hazards in food, cosmetics and pharmaceuticals etc? In a world where people are becoming increasingly aware of their allergies, this up to date one-stop reference will prove an invaluable addition to the shelves of any researcher in academia, government, regulatory bodies, public health officials and, of course, the food, cosmetics and pharmaceuticals industries will find the book to be of particular relevance.



Toxicology Of Skin


Toxicology Of Skin
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Author : Howard I. Maibach
language : en
Publisher: CRC Press
Release Date : 2001-03-15

Toxicology Of Skin written by Howard I. Maibach and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-03-15 with Medical categories.


Toxic injury to the skin in the general population, and particularly in western populations, is on the increase. This is partly due to the expanding number of natural and man-made chemicals present in our everyday environment. The need for a thorough understanding of the skin, and the mechanisms of toxicity therein, has never been more pressing. Th



Bioactive Dietary Factors And Plant Extracts In Dermatology


Bioactive Dietary Factors And Plant Extracts In Dermatology
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Author : Ronald Ross Watson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-28

Bioactive Dietary Factors And Plant Extracts In Dermatology written by Ronald Ross Watson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-28 with Medical categories.


The role of Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology provides current and concise scientific appraisal of the efficacy of foods, nutrients, herbs, and dietary supplements in preventing dermal damage and cancer as well as improving skin health. This important new volume reviews and presents new hypotheses and conclusions on the effects of different bioactive foods and their components derived particularly from vegetables, fruits, and herbs. Primary emphasis is on treatment and prevention of dermal damage focusing on skin cancers with significant health care costs and mortality. Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology brings together expert clinicians and researchers working on the different aspects of supplementation, foods, and plant extracts and nutrition and skin health. Their expertise provides the most current knowledge in the field and will serve as the foundation for advancing future research.



Irritant Dermatitis


Irritant Dermatitis
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Author : Ai-Lean Chew
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-06-18

Irritant Dermatitis written by Ai-Lean Chew and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-18 with Medical categories.


Irritant dermatitis is a common condition, accounting for a significant proportion of occupational skin disease. The recent advent of non-invasive skin bioengineering technology has accelerated dermatology research in this field. This book comprises an exhaustive reference text on irritant contact dermatitis, covering all aspects of the condition: clinical features, epidemiology, prevention and therapy, prognosis, mechanisms, pathology and regulatory issues. The book also presents novel in vitro and in vivo research techniques and findings. As irritant dermatitis affects multiple specialties, the audience for this book is wide, including clinical and investigative dermatologists, allergists, toxicologists, pharmaceutical scientists, occupational and environmental physicians, public health physicians, cosmetologists and skin bioengineers.



Toxicology Of The Skin


Toxicology Of The Skin
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Author : Nancy A. Monteiro-Riviere
language : en
Publisher: CRC Press
Release Date : 2010-02-17

Toxicology Of The Skin written by Nancy A. Monteiro-Riviere and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-17 with Medical categories.


This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin. Any defects or perturbations to this barr



Handbook Of Cosmetic Science And Technology


Handbook Of Cosmetic Science And Technology
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Author : André O. Barel
language : en
Publisher: CRC Press
Release Date : 2005-11-04

Handbook Of Cosmetic Science And Technology written by André O. Barel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-04 with Medical categories.


Ranging from studies on the structure and function of the skin to research on a wide array of cosmetic compounds, this Second Edition updates readers on the latest regulatory guidelines, new cosmetic ingredients, state-of-the-art safety assessment technologies, and anticipated trends in the market-keeping pace with rapid advancements in chemistry, physics, biology, cosmetology, and toxicology to stand alone as the foremost guide to the subject.



Dermatotoxicology


Dermatotoxicology
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Author : Klaus Peter Wilhelm
language : en
Publisher: CRC Press
Release Date : 2007-11-26

Dermatotoxicology written by Klaus Peter Wilhelm and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-26 with Medical categories.


Reflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated and expanded to reflect the latest developments, the seventh edition includes fundamental information on the mechanisms of action of toxic substances on the skin and practical information on the many methods for evaluating dermal toxicity. Unparalleled in its coverage and broad in scope, with the addition of 34 new chapters, this volume keeps pace with the expanding science. A perennial bestseller, this definitive text explores the latest developments in the field. With contributions from leading international experts, it continues the tradition of providing unsurpassed theoretical and practical guidance.