Biochemical Oscillations And Cellular Rhythms
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Biochemical Oscillations And Cellular Rhythms
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Author : A. Goldbeter
language : en
Publisher:
Release Date : 1996-01
Biochemical Oscillations And Cellular Rhythms written by A. Goldbeter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01 with Science categories.
This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. Clarifying the mechanism of these oscillatory phenomena is of key importance for understanding the origin as well as the physiological function of these rhythms, and the conditions in which simple periodic behaviour transforms into complex oscillations including bursting and chaos. It will appeal to graduate students and researchers in a wide variety of fields. On the one hand, it will be of interest to life scientists such as biochemists, cell biologists, medical scientists, pharmacologists and chronobiologists. On the other hand, scientists studying nonlinear phenomena, including oscillations and chaos, in chemistry, physics, mathematics and mathematical biology will also find these ideas of value.
Biochemical Oscillations And Cellular Rhythms
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Author : Albert Goldbeter
language : en
Publisher: Cambridge University Press
Release Date : 1997-04-03
Biochemical Oscillations And Cellular Rhythms written by Albert Goldbeter and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-04-03 with Science categories.
This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. The approach rests on the analysis of theoretical models closely related to experimental observations. Among the main rhythms considered are glycolytic oscillations observed in yeast and muscle, oscillations of cyclic AMP in Dictyostelium amoebae, intracellular calcium oscillation observed in a variety of cell types, the mitotic oscillator that drives the cell division cycle in eukaryotes, pulsatile hormone signaling, and circadian rhythms in Drosophila. This book will be of interest to life scientists such as biochemists, cell biologists, chronobiologists, medical scientists and pharmacologists. In addition, it will appeal to scientists studying nonlinear phenomena, including oscillations and chaos, in chemistry, physics, mathematics and theoretical biology.
Computational Cell Biology
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Author : Christopher P. Fall
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-06-04
Computational Cell Biology written by Christopher P. Fall and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-04 with Science categories.
This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.
Biological Clocks Rhythms And Oscillations
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Author : Daniel B. Forger
language : en
Publisher: MIT Press
Release Date : 2024-08-06
Biological Clocks Rhythms And Oscillations written by Daniel B. Forger and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-06 with Science categories.
An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.
Cellular Oscillatory Mechanisms
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Author : Miguel Maroto
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-19
Cellular Oscillatory Mechanisms written by Miguel Maroto and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-19 with Medical categories.
Oscillatory dynamics are a central feature of a wide range of biological processes. This text fully explores cellular oscillations, focusing particularly on elucidating the basic mechanisms that underlie these oscillations.
Physics Of Biological Oscillators
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Author : Aneta Stefanovska
language : en
Publisher: Springer Nature
Release Date : 2021-05-05
Physics Of Biological Oscillators written by Aneta Stefanovska and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-05 with Science categories.
This book, based on a selection of invited presentations from a topical workshop, focusses on time-variable oscillations and their interactions. The problem is challenging, because the origin of the time variability is usually unknown. In mathematical terms, the oscillations are non-autonomous, reflecting the physics of open systems where the function of each oscillator is affected by its environment. Time-frequency analysis being essential, recent advances in this area, including wavelet phase coherence analysis and nonlinear mode decomposition, are discussed. Some applications to biology and physiology are described. Although the most important manifestation of time-variable oscillations is arguably in biology, they also crop up in, e.g. astrophysics, or for electrons on superfluid helium. The book brings together the research of the best international experts in seemingly very different disciplinary areas.
Systems Biology Of Cell Signaling
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Author : James E. Ferrell
language : en
Publisher: Garland Science
Release Date : 2021-09-28
Systems Biology Of Cell Signaling written by James E. Ferrell and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-28 with Science categories.
How can we understand the complexity of genes, RNAs, and proteins and the associated regulatory networks? One approach is to look for recurring types of dynamical behavior. Mathematical models prove to be useful, especially models coming from theories of biochemical reactions such as ordinary differential equation models. Clever, careful experiments test these models and their basis in specific theories. This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing on modeling, theory, and experimentation. Early chapters summarize the basic building blocks of signaling systems: binding/dissociation, synthesis/destruction, and activation/inactivation. Subsequent chapters introduce various basic circuit devices: amplifiers, stabilizers, pulse generators, switches, stochastic spike generators, and oscillators. All chapters consistently use approaches and concepts from chemical kinetics and nonlinear dynamics, including rate-balance analysis, phase plane analysis, nullclines, linear stability analysis, stable nodes, saddles, unstable nodes, stable and unstable spirals, and bifurcations. This textbook seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools and insights needed to apply modeling and theory to interesting biological processes. Key Features: · Full-color illustration program with diagrams to help illuminate the concepts · Enables the reader to apply modeling and theory to the biological processes · Further Reading for each chapter · High-quality figures available for instructors to download
Introduction To Metabolic And Cellular Engineering An Second Edition
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Author : Sonia Del Carmen Cortassa
language : en
Publisher: World Scientific
Release Date : 2011-12-28
Introduction To Metabolic And Cellular Engineering An Second Edition written by Sonia Del Carmen Cortassa and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-28 with Technology & Engineering categories.
Metabolic and Cellular Engineering (MCE) is more than an exciting scientific enterprise. It has become the cornerstone for coping with the challenges ahead of mankind. Continuous developments, new concepts, and technological innovations will enable us to deal with emerging challenges, and solve problems once thought impossible ten years ago. Challenges in MCE are broad- from unraveling fundamental aspects of cellular function to meeting unsatiated energy and food demands that are rising in parallel with population growth.In charting the progress of MCE during the last decade, we could not help but feel in awe of the enormous strides of progress made from the nascent Metabolic Engineering to the Systems Bioengineering of today. The burgeoning availability of genomic sequences from diverse species has been spectacular. It has become the engine that drives the genetic means for the modification of existing organisms and the generation of synthetic, man-made ones. From the initial attempts at purposeful genetic modification of a cell for the production of valuable compounds, we have now moved on to changing microbes genetically or metabolically.The arsenal of experimental and theoretical tools available for Metabolic and Cellular Engineering has expanded enormously, driven by the re-emergence of Physiology as Systems Biology. The revival of the concept of networks fueled by new developments has become central to Systems Biology. Networks represent an integrative vision of how processes of disparate nature relate to each other, and as such is becoming a key analytical and conceptual tool for MCE. This book reflects and addresses all these ongoing changes while providing the essential conceptual and analytical tools needed to understand and work in the MCE research field.
Membranes And Circadian Rythms
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Author : Jean-Luc Guisset
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Membranes And Circadian Rythms written by Jean-Luc Guisset and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Rambling of an elderly biochemist Most biochemists of my generation, who were trying to discover the pathways of metabolism, simply ignored membranes; or regarded them as a nuisance. Think of the difficulties experienced in studies on cytochromoxidase which one could not separate from « insoluble material )} or again of the desperate efforts during a quarter of a century to unravel oxidative phosphorylation without paying much attention to lipidic membranes, altough the system was known to be associated with them. Hence the amazement and the general skepticism that met at first Mitchell's theory, which was giving membranes the central function they deserve in oxidative phosphorylation and photosynthesis. This, I believe, was a turning point; enzymologists thereafter became aware of the importance of the membranes. Neurophysiologists, of course, had long been interested in the outer cell membrane with its electrical properties and the ion potentials. Histologists and electronmicroscopists also, who observed inside the cell.organelles of which membranes are essential components: nucleus, nucleoli, mitchondria, lysosomes,Golgi apparatus, endoplasmic reticulum, chloroplasts. For them at least, a cell did not look like a mere bag full of enzymes and small molecules; they knew, they could see that it is a highly structured system divided into many compartments by membranous formations.
Mechanisms And Biological Significance Of Pulsatile Hormone Secretion
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Author : Derek J. Chadwick
language : en
Publisher: John Wiley & Sons
Release Date : 2003-10-31
Mechanisms And Biological Significance Of Pulsatile Hormone Secretion written by Derek J. Chadwick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-10-31 with Science categories.
This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage includes the basic mechanisms involved in hormone pulsatility, the significance of pulsatility in normal and disease conditions, the relevance of circadian rhythms, changes with ageing, and detailed consideration of specific peptide hormone systems. This book includes contributions from professionals working in both basic and clinical research and reveals much new and exciting work in this area and promises new research directions.