Cellular Oscillatory Mechanisms
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Cellular Oscillatory Mechanisms
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Author : Miguel Maroto
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-19
Cellular Oscillatory Mechanisms written by Miguel Maroto and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-19 with Medical categories.
Oscillatory dynamics are a central feature of a wide range of biological processes. This text fully explores cellular oscillations, focusing particularly on elucidating the basic mechanisms that underlie these oscillations.
Biochemical Oscillations And Cellular Rhythms
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Author : A. Goldbeter
language : en
Publisher: Cambridge University Press
Release Date : 1996-01-26
Biochemical Oscillations And Cellular Rhythms written by A. Goldbeter and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01-26 with Medical categories.
This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. Clarifying the mechanism of these oscillatory phenomena is of key importance for understanding the origin as well as the physiological function of these rhythms, and the conditions in which simple periodic behaviour transforms into complex oscillations, including bursting and chaos. The approach rests on the analysis of theoretical models closely related to experimental observations. Among the main rhythms considered are glycolytic oscillations observed in yeast and muscle, oscillations of cyclic AMP in Dictyostelium amoebae, intracellular calcium oscillations observed in a variety of cell types, the mitotic oscillator that drives the cell division cycle in eukaryotes, and circadian oscillations of the period protein (PER) in Drosophila. For each of these phenomena, experimental facts are reviewed and mathematical models presented.
Molecular And Cellular Mechanisms In Reproduction And Early Development
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Author : Rafael A. Fissore
language : en
Publisher: Frontiers Media SA
Release Date : 2019-08-20
Molecular And Cellular Mechanisms In Reproduction And Early Development written by Rafael A. Fissore and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-20 with categories.
The Research Topic aims to support progress towards understanding the different sets of developmental processes that are absolutely required to complete all the steps essential for successful embryonic development, under physiological conditions. We sought contributions that dealt with single cells, interaction between cells as well as intra- and extracellular signal transduction. The Research Topic presents original studies covering experimental and theoretical approaches, descriptions of new methodologies, reviews and opinions.
Jasper S Basic Mechanisms Of The Epilepsies
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Author : Jeffrey Noebels
language : en
Publisher: OUP USA
Release Date : 2012-06-29
Jasper S Basic Mechanisms Of The Epilepsies written by Jeffrey Noebels and has been published by OUP USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-29 with Medical categories.
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Thalamic Function Beyond A Simple Relay
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Author : Vincenzo Crunelli
language : en
Publisher: Frontiers Media SA
Release Date : 2016-05-20
Thalamic Function Beyond A Simple Relay written by Vincenzo Crunelli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-20 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
The thalamus is often described as a relay. Typified by sensory pathways, this concept leads to thalamic nuclei being viewed as areas that passively streams information from a single source to the cortex, without affecting the nature of that information. However, diverse intrathalamic connections, the varying synaptic and membrane properties of thalamic neurons and the large number of inputs from non-sensory sources make the idea that the thalamus is just a passive relay unlikely. Furthermore, a large number of thalamic nuclei are not primarily driven by sensory signals nor do they exclusively target the cortex, meaning the thalamus must do more than simply pass sensory signals to the cortex. Finally, there is a wealth of research demonstrating that the thalamus does indeed function in ways that are not captured by the concept of a simple relay. So why, given all of this, is the primary paradigm for describing the thalamus, a relay? This Research Topic covers original research, reviews and hypotheses on thalamic function that explore the concept that the thalamus performs computational tasks other than simply passively relaying information.
Biological Clocks Rhythms And Oscillations
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Author : Daniel B. Forger
language : en
Publisher: MIT Press
Release Date : 2024-08-06
Biological Clocks Rhythms And Oscillations written by Daniel B. Forger and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-06 with Science categories.
An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.
Encyclopedia Of Basic Epilepsy Research
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-05-27
Encyclopedia Of Basic Epilepsy Research written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-27 with Medical categories.
As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent updates and additions, while the limited edition print version provides another option for owning this content. The Encyclopedia of Basic Epilepsy Research is an essential resource for researchers of all levels and clinicians who study epilepsy. The only comprehensive reference for basic research and current activities in epilepsy Electronic format provides fast and easy access to updates and additions, with limited print version available as well Contains over 85 articles, all written by experts in epilepsy research
Advances In Cell Membrane Research And Application 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-06-21
Advances In Cell Membrane Research And Application 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-21 with Science categories.
Advances in Cell Membrane Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cell Membrane Structures in a concise format. The editors have built Advances in Cell Membrane Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cell Membrane Structures in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Cell Membrane Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
The Regulation Of Cellular Systems
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Author : Reinhart Heinrich
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Regulation Of Cellular Systems written by Reinhart Heinrich and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
There is no doubt that nowadays, biology benefits greatly from mathematics. In particular, cellular biology is, besides population dynamics, a field where tech niques of mathematical modeling are widely used. This is reflected by the large number of journal articles and congress proceedings published every year on the dynamics of complex cellular processes. This applies, among others, to metabolic control analysis, where the number of articles on theoretical fundamentals and experimental applications has increased for about 15 years. Surprisingly, mono graphs and textbooks dealing with the modeling of metabolic systems are still exceptionally rare. We think that now time is ripe to fill this gap. This monograph covers various aspects of the mathematical description of enzymatic systems, such as stoichiometric analysis, enzyme kinetics, dynamical simulation, metabolic control analysis, and evolutionary optimization. We believe that, at present, these are the main approaches by which metabolic systems can be analyzed in mathematical terms. Although stoichiometric analysis and enzyme kinetics are classical fields tracing back to the beginning of our century, there are intriguing recent developments such as detection of elementary biochemical syn thesis routes and rate laws for the situation of metabolic channeling, which we have considered worth being included. Evolutionary optimization of metabolic systems is a rather new field with promising prospects. Its goal is to elucidate the structure and functions of these systems from an evolutionary viewpoint.
Cortical Oscillations In Health And Disease
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Author : Roger Traub, MD
language : en
Publisher: Oxford University Press
Release Date : 2010-05-12
Cortical Oscillations In Health And Disease written by Roger Traub, MD and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-12 with Medical categories.
This book first reviews the case that brain oscillations not only are important for cognition, as long suspected, but also play a part in the expression of signs and symptoms of neuropsychiatric disorders. The cellular mechanisms of many of the clinically relevant oscillations have been studied by the authors and their colleagues, using in vitro slice methods as well as detailed computer simulations. A surprising insight is that gap junctions between principal neurons play an absolutely critical role in so many types of oscillation in neuronal populations; oscillations are not just the result of properties of individual neurons and their synaptic connections. Furthermore, the way in which gap junctions produce oscillations in the cortex is novel, involving as it does global properties of networks, rather than just the time constants of membrane currents. This insight has implications for therapeutics as well as for our understanding of normal brain functions.