Biodefence
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Biodefence
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Author : Sergey Mikhalovsky
language : en
Publisher: Springer
Release Date : 2011-01-15
Biodefence written by Sergey Mikhalovsky and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-15 with Medical categories.
This book focuses on defence against biological warfare with an emphasis on applications of modern technologies and advanced materials in detection, health protection and medical treatment of the population. Specific topics include high-throughput sensitive detection methods, advanced nanostructured materials and techniques for external and internal protection of human health, as well as extracorporeal methods, adsorptive materials and bacteriophages decontaminating the human organism, and neutralising incorporated CBRN agents. The contributions describe recent developments in the field of biodefence aimed at protecting population against terrorism and terror related events. Broader approaches to reducing the impact of environmental pollution on human health and improving efficiency of medical treatment of patients with viral infections, poisoning and organ failure are also discussed.
Biodefense
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Author : Michael S. Bronze
language : en
Publisher: Taylor & Francis
Release Date : 2005
Biodefense written by Michael S. Bronze and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
The anthrax attacks by bioterrorists in the USA in October 2001 served to highlight our vulnerability to biological warfare and to act as an impetus for a massive increase in funding for biodefense research. In this timely book, top biodefense experts critically review every aspect of this complex issue. The microbiology, diagnosis, pathogenesis, epidemiology, infection control and novel therapeutics for all the key pathogens involved are comprehensively covered. Biodefense is currently focused on anthrax, smallpox, plague, tularemia, botulism and viral hemorrhagic fevers and entire chapters are devoted to each of these topics. Further chapters cover the bioterrorism threat from other diseases including brucellosis, glanders, melioidosis, psittacosis, Q fever, typhoid, gastroenteritis and cryptosporidiosis. Biological toxins derived from living organisms, such as the epsilon toxin derived from Clostridium perfringens, mycotoxins and plant-derived toxins such as ricin are also reviewed in detail. Two fascinating chapters are devoted to agroterrorism, the use of infectious agents that target animals and plants to decimate the food supply. Additional chapters cover emerging pathogens and novel bio-engineered agents that could be used in bioterrorism. The book also covers hospital preparedness, infection control, psychosocial issues, and the evolving methods for surveillance and detection in biodefence.
Pathogens For War
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Author : Donald H. Avery
language : en
Publisher: University of Toronto Press
Release Date : 2013-04-28
Pathogens For War written by Donald H. Avery and has been published by University of Toronto Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-28 with History categories.
Pathogens for War explores how Canada and its allies have attempted to deal with the threat of germ warfare, one of the most fearful weapons of mass destruction, since the Second World War. In addressing this subject, distinguished historian Donald Avery investigates the relationship between bioweapons, poison gas, and nuclear devices, as well as the connection between bioattacks and natural disease pandemics. Avery emphasizes the crucially important activities of Canadian biodefence scientists – beginning with Nobel Laureate Frederick Banting – at both the national level and through cooperative projects within the framework of an elaborate alliance system. Delving into history through a rich collection of declassified documents, Pathogens for War also devotes several chapters to the contemporary challenges of bioterrorism and disease pandemics from both national and international perspectives. As such, readers will not only learn about Canada’s secret involvement with biological warfare, but will also gain new insights into current debates about the peril of bioweapons – one of today’s greatest threats to world peace.
Breeding Bio Insecurity
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Author : Lynn C. Klotz
language : en
Publisher: University of Chicago Press
Release Date : 2009-10-15
Breeding Bio Insecurity written by Lynn C. Klotz and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-15 with Technology & Engineering categories.
In the years since the 9/11 attacks—and the subsequent lethal anthrax letters—the United States has spent billions of dollars on measures to defend the population against the threat of biological weapons. But as Lynn C. Klotz and Edward J. Sylvester argue forcefully in Breeding Bio Insecurity, all that money and effort hasn’t made us any safer—in fact, it has made us more vulnerable. Breeding Bio Insecurity reveals the mistakes made to this point and lays out the necessary steps to set us on the path toward true biosecurity. The fundamental problem with the current approach, according to the authors, is the danger caused by the sheer size and secrecy of our biodefense effort. Thousands of scientists spread throughout hundreds of locations are now working with lethal bioweapons agents—but their inability to make their work public causes suspicion among our enemies and allies alike, even as the enormous number of laboratories greatly multiplies the inherent risk of deadly accidents or theft. Meanwhile, vital public health needs go unmet because of this new biodefense focus. True biosecurity, the authors argue, will require a multipronged effort based in an understanding of the complexity of the issue, guided by scientific ethics, and watched over by a vigilant citizenry attentive to the difference between fear mongering and true analysis of risk. An impassioned warning that never loses sight of political and scientific reality, Breeding Bio Insecurity is a crucial first step toward meeting the evolving threats of the twenty-first century.
Biodefense In The Age Of Synthetic Biology
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2019-01-05
Biodefense In The Age Of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-05 with Technology & Engineering categories.
Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.
Biodefense
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Author : James R. Swearengen
language : en
Publisher: CRC Press
Release Date : 2005-11-21
Biodefense written by James R. Swearengen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-21 with Medical categories.
The importance attached to rapidly developing our biodefensive capabilities has recently resulted in a significantly increased funding for biodefense research. Accordingly, researchers will respond with an effort equal to the challenge, producing an impressive body of findings. To ensure that this effort continues in the most efficient manne
Biodefense Research Supporting The Dod
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Author : Coleen K. Martinez
language : en
Publisher:
Release Date : 2007
Biodefense Research Supporting The Dod written by Coleen K. Martinez and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Biological warfare categories.
Applied Biosecurity Global Health Biodefense And Developing Technologies
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Author : Ryan N. Burnette
language : en
Publisher: Springer Nature
Release Date : 2021-05-31
Applied Biosecurity Global Health Biodefense And Developing Technologies written by Ryan N. Burnette and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-31 with Political Science categories.
This book describes an adaptable biothreat assessment process to complement overall biorisk management programs, incorporating threat management and the unique natures of biological assets. Further, this book examines the nexus between public health, international security, and developing technologies, building a case for augmenting biosecurity to levels beyond the laboratory constraints. With the face of biological and biomedical sciences changing, this book describes how with proper biosecurity development, these can become assets, rather than liabilities, to secure our world from natural and man-made biological disasters. The world is changing rapidly with respect to developing threats, such as terrorism, and dual-use technologies, such as synthetic biology, that are challenging how we think about biosafety and biosecurity. Further, the fields of public health and international security are colliding, as both of these share the common enemy: intentional or natural biological incidents. To date, biosecurity has been limited to laboratory-level application, and complicating efforts, and lacks credentialed biosecurity professionals skilled in both the biological sciences and threat management techniques. The result is a fragmented field of practice, with tremendous need, from the lab to the outbreak. Underpinning these principles is the SARS-CoV-2 coronavirus pandemic, providing a historic milestone to examine biosecurity through a global lens. This book describes biosecurity as a set of practices and principles to be augmented out of the constrained laboratory environment, and applied to larger efforts, such as international threat reduction and biological incident management.
Biodefense Research Methodology And Animal Models Second Edition
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Author : James R. Swearengen
language : en
Publisher: CRC Press
Release Date : 2012-02-16
Biodefense Research Methodology And Animal Models Second Edition written by James R. Swearengen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-16 with Medical categories.
Significant advances have been made in animal model development for biological research since the publication of the first edition of this volume, and the ramifications of the FDA’s Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, Biodefense Research Methodology and Animal Models, Second Edition spans the spectrum of coverage from basic research to advanced development of medical countermeasures. Topics discussed in this volume include: A history of biological agents as weapons, from the use of corpses to contaminate water supplies to modern day anthrax attacks Concepts and strategies involved in biowarfare and bioterrorism The development, validation, and importance of animal models in biodefense research Infectious disease aerobiology Studies involving anthrax, glanders, plague, tularemia, Q fever, alphaviruses, orthopoxviruses, and a new chapter on brucellosis Animal models for viral hemorrhagic fevers Botulinum and Ricin toxins Staphylococcal and streptococcal superantigens As the scientific community works diligently to protect the world’s population from the misuse of infectious organisms and toxins, it is imperative that researchers stay abreast of the latest techniques for biodefense research. Exploring in vivo and in vitro assays, this volume brings researchers up to date on the latest information on bacterial and viral infectious agents and biological toxins considered to pose the greatest threats to public safety. In addition, the contributors take a step toward minimizing the use of animals in further experiments by presenting documented findings that can be built upon.
A Proposed Framework For Identifying Potential Biodefense Vulnerabilities Posed By Synthetic Biology
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-12-20
A Proposed Framework For Identifying Potential Biodefense Vulnerabilities Posed By Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-20 with Science categories.
Building on an increasingly sophisticated understanding of naturally occurring biological processes, researchers have developed technologies to predictably modify or create organisms or biological components. This research, known collectively as synthetic biology, is being pursued for a variety of purposes, from reducing the burden of disease to improving agricultural yields to remediating pollution. While synthetic biology is being pursued primarily for beneficial and legitimate purposes, it is possible to imagine malicious uses that could threaten human health or military readiness and performance. Making informed decisions about how to address such concerns requires a comprehensive, realistic assessment. To this end, the U.S. Department of Defense, working with other agencies involved in biodefense, asked the National Academies of Sciences, Engineering, and Medicine to develop a framework to guide an assessment of the security concerns related to advances in synthetic biology, to assess the level of concern warranted for various advances and identify areas of vulnerability, and to prioritize options to address these vulnerabilities. This interim report proposes a framework for identifying and prioritizing potential areas of concern associated with synthetic biologyâ€"a tool to aid the consideration of concerns related to synthetic biology. The framework describes categories of synthetic biology technologies and applicationsâ€"such as genome editing, directed evolution, and automated biological designâ€"and provides a set of initial questions to guide the assessment of concern related to these technologies and applications.