Bioengineering Aspects Of The Lung
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Bioengineering Aspects Of The Lung
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Author : John Burnard West
language : en
Publisher:
Release Date : 1977
Bioengineering Aspects Of The Lung written by John Burnard West and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Medical categories.
Bioengineering Aspects In The Design Of Gas Exchangers
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Author : John N. Maina
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-24
Bioengineering Aspects In The Design Of Gas Exchangers written by John N. Maina and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-24 with Science categories.
This book encapsulates over three decades of the author’s work on comparative functional respiratory morphology. It provides insights into the mechanism(s) by which respiratory means and processes originated and advanced to their modern states. Pertinent cross-disciplinary details and facts have been integrated and reexamined in order to arrive at more robust answers to questions regarding the basis of the functional designs of gas exchangers. The utilization of oxygen for energy production is an ancient process, the development and progression of which were underpinned by dynamic events in the biological, physical, and chemical worlds. Many books that have broached the subject of comparative functional respiratory biology have only described the form and function of the ‘end-product,’ the gas exchanger; they have scarcely delved into the factors and the conditions that motivated and steered the development from primeval to modern respiratory means and processes. This book addresses and answers broad questions concerning the critical synthesis of multidisciplinary data, and clarifies previously cryptic aspects of comparative respiratory biology.
Bioengineering Approaches To Pulmonary Physiology And Medicine
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Author : M.C.K. Khoo
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-20
Bioengineering Approaches To Pulmonary Physiology And Medicine written by M.C.K. Khoo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-20 with Technology & Engineering categories.
As the current millennium steams towards a close, one cannot help but look with amazement at the incredible amount of progress that has been achieved in medicine in just the last few decades. A key contributing factor to this success has been the importation and blending of ideas and techniques from disciplines outside the traditional borders of medical science. In recent years, the most well-known example is the cross-pollination between molecular biology and medicine. Advances driven by this potent combination have spawned the vision of a future where cures based on gene therapy become commonplace. Yet, as we continue our search for "magic bullets" in the quest to eradicate disease, it important to recognize the value of other less-heralded interdisciplinary efforts that have laid a large part of the foundation of present-day medicine. In pulmonary medicine, the contribution from the bioengineers (a diverse collection of individuals cross-bred to various degrees in mathematical modeling and experimental physiology) has been larger and more sustained than in many other medical specialties. It is easy to point to the vast array of ventilators, blood-gas analyzers, oximeters, pulmonary function devices, and respiration monitors that are present in any modern clinical setting as solid evidence of the successful synergy between engineering science and pulmonary medicine. However, one must not forget the less tangible, but perhaps more important, contributions that have been derived from mathematical modeling and computer simulation, without which many of these modern instruments would not have come into existence.
Bioengineering Aspects In The Design Of Gas Exchangers
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Author : John Maina
language : en
Publisher: Springer
Release Date : 2013-01-02
Bioengineering Aspects In The Design Of Gas Exchangers written by John Maina and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-02 with Science categories.
This book encapsulates over three decades of the author’s work on comparative functional respiratory morphology. It provides insights into the mechanism(s) by which respiratory means and processes originated and advanced to their modern states. Pertinent cross-disciplinary details and facts have been integrated and reexamined in order to arrive at more robust answers to questions regarding the basis of the functional designs of gas exchangers. The utilization of oxygen for energy production is an ancient process, the development and progression of which were underpinned by dynamic events in the biological, physical, and chemical worlds. Many books that have broached the subject of comparative functional respiratory biology have only described the form and function of the ‘end-product,’ the gas exchanger; they have scarcely delved into the factors and the conditions that motivated and steered the development from primeval to modern respiratory means and processes. This book addresses and answers broad questions concerning the critical synthesis of multidisciplinary data, and clarifies previously cryptic aspects of comparative respiratory biology.
Fundamental Structural Aspects And Features In The Bioengineering Of The Gas Exchangers Comparative Perspectives
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Author : J.N. Maina
language : en
Publisher: Springer
Release Date :
Fundamental Structural Aspects And Features In The Bioengineering Of The Gas Exchangers Comparative Perspectives written by J.N. Maina and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on with Science categories.
The history of biology is replete with examples of how comparative biology helped clarify the meaning of structure and function in complex animals. Indeed, without the comparative approach to biology, the birth of physiology would have been delayed. Fishman (1979) Comparative morphologists are challenged to discern the changes that have occurred in evolution and development of the forms and states of organisms as well as to explain the factors that compelled them (e.g. Dullemeijer 1974). The main objective of this contribution is to present what I deem to be some of the fundamental structural aspects in the design of respiratory or gans while debating and speculating on when, how and why these states were founded. My main thesis is that the modern gas exchangers are products of protracted processes that have en tailed adaptation to specific environments and lifestyles. Only those feasible designs that have proven adequately competent in meeting demands for molecular oxygen have been preserved. Unfortunately, August Krogh's (Krogh 1941) and Pierre Dejours' (Dejours 1975) seminal works on the comparative physiology of the respiratory organs have not been paralleled by equally exten sive and detailed morphological work. Our approach has been to look into the limiting functional properties as regards the respi ratory capacities of gas exchangers while finding out the specific structural adaptations that have evolved to meet the metabolic needs or to look into form and to discern how it limits function. This has allowed a deduction of structure-function correlation.
Human Respiration
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Author : Vladimir Kulish
language : en
Publisher: WIT Press
Release Date : 2006
Human Respiration written by Vladimir Kulish and has been published by WIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Technology & Engineering categories.
This title discusses the anatomy and physiology of human respiration, some of the newest macro- and microscopic models of the respiratory system, numerical simulation and computer visualization of gas transport phenomena, and applications of these models to medical diagnostics, treatment and safety.
Stem Cells In The Lung
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Author : Ivan Bertoncello
language : en
Publisher: Springer
Release Date : 2015-10-31
Stem Cells In The Lung written by Ivan Bertoncello and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-31 with Science categories.
This book presents a comprehensive overview of the current understanding of the organization of endogenous lung stem and progenitor cell compartments during fetal lung development, postnatal lung growth and in adulthood. Progressing stage by stage, the chapters on fetal lung development emphasize the integrated role of epithelial, stromal, vascular and neural cell elements in building a functional lung, while the subsequent chapters on adult lung regeneration describe the nature and properties of adult lung stem/progenitor cells distributed along the proximal-distal axis of the airway tree. The chapters on regulation of lung regeneration and repair discuss how regenerative cells interact with their niche microenvironment and how regulation of lung regeneration and repair in the steady state and following injury recapitulates ontogeny. And, lastly, the chapters on cellular therapies for lung disease and bioengineering the lung focus on promising emerging therapies and approaches in lung regenerative medicine. The scope of this volume of the Stem Cell Biology and Regenerative Medicine series focuses on exploring the topic of building and rebuilding the lung from a cellular rather than a molecular perspective. Thus, the section on cellular therapies does not include extensive coverage of each of the numerous lung diseases, including cancer, which could be amenable to stem cell-based therapies, although the final chapter does include some discussion on the future prospects and challenges. All of the contributors are working on the cutting edge of the lung stem cell field, making this book essential reading for those with an interest in the field of lung stem cell biology and the potential role of cellular therapies and tissue bioengineering approaches in lung regenerative medicine, including biomedical scientists, graduate students, post-graduate researchers and respiratory clinicians.
Cardiovascular And Respiratory Bioengineering
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Author : Nenad Filipovic
language : en
Publisher: Academic Press
Release Date : 2022-05-12
Cardiovascular And Respiratory Bioengineering written by Nenad Filipovic and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-12 with Technology & Engineering categories.
Cardiovascular and Respiratory Bioengineering focuses on computational tools and modeling techniques in cardiovascular and respiratory systems that help develop bioengineered solutions. The book demonstrates how these technologies can be utilized in order to tackle diseases and medical issues. It provides practical guidance on how a bioengineering or medical problem can be modeled, along with which computational models can be used. Topics include computer modeling of Purkinje fibers with different electrical potential applied, modeling of cardiomyopathies caused by sarcomeric gene mutations, altered sarcomere function, perturbations in intracellular ion homeostasis, impaired myocardial energetics at reduced costs, and more. The book also discusses blood flow through deformable blood vessels in human aorta, abdominal aortic aneurysm, carotid artery, coronary artery and plaque formation, along with content on stent deployment modeling and stent design and optimization techniques. Features practical applications of cardiovascular and respiratory technology to counteract diseases Includes detailed steps for the modeling of cardiovascular and respiratory systems Explores a range of different modeling methods, including computational modeling, predictive modeling and multi-scale modeling Covers biological processes and biomechanics relevant to cardiovascular and respiratory bioengineering
Lung Function Testing In The 21st Century
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Author : Clara Ionescu
language : en
Publisher: Academic Press
Release Date : 2018-11-19
Lung Function Testing In The 21st Century written by Clara Ionescu and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-19 with Science categories.
Lung Function Testing in the 21st Century: Methodologies and Tools Bridging Engineering to Clinical Practice covers the complete aspects of lung function testing, ranging from standardized to newly introduced (IOS, FOT) methods. It provides an updated overview of advances in respiratory engineering, along with advice on which lung function tests are appropriate for which purpose. The author discusses non-standardized lung function testing, methods, clinical tests, diagnosis and future perspectives. Lung function measurement devices and protocols are also covered. This book covers multidisciplinary domains, bringing new technology ideas from mathematics, physics, biology and engineering into the field of respiratory engineering. Users will find a single resource that brings together all of the disparate information on lung function testing technology currently contained in many journal articles. Bridges the gap between engineers and clinicians with regard to pulmonary function techniques, from research, to design and clinical practice Provides a comprehensive overview of all tools available for lung function testing, detailing their pros and cons Includes information on incorporating new devices into existing procedures, along with methods for lung function testing
Respiratory Mechanics
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Author : Theodore A. Wilson
language : en
Publisher: Springer
Release Date : 2016-04-21
Respiratory Mechanics written by Theodore A. Wilson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-21 with Science categories.
This book thoroughly covers each subfield of respiratory mechanics: pulmonary mechanics, the respiratory pump, and flow. It presents the current understanding of the field and serves as a guide to the scientific literature from the golden age of respiratory mechanics, 1960 - 2010. Specific topics covered include the contributions of surface tension and tissue forces to lung recoil, the gravitational deformation of the lung, and the interdependence forces that act on pulmonary airways and blood vessels. The geometry and kinematics of the ribs is also covered in detail, as well as the respiratory action of the external and internal intercostal muscles, the mechanics of the diaphragm, and the quantitative compartmental models of the chest wall is also described. Additionally, flow in the airways is covered thoroughly, including the wave-speed and viscous expiratory flow-limiting mechanisms; convection, diffusion and the stationary front; and the distribution of ventilation. This is an ideal book for respiratory physiologists, pneumologists, exercise physiologists, and critical care physicians. This book also: Maximizes reader insights into current and landmark respiratory mechanics researchConcisely yet thoroughly explores the current research on pulmonary mechanics, the respiratory pump, and flow Serves as an invaluable guide for those entering the field, or those seeking to expand their knowledge of it