Biofluid And Tissue Analysis For Drugs Including Hypolipidaemics


Biofluid And Tissue Analysis For Drugs Including Hypolipidaemics
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Biofluid And Tissue Analysis For Drugs Including Hypolipidaemics


Biofluid And Tissue Analysis For Drugs Including Hypolipidaemics
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Author : Eric Reid
language : en
Publisher:
Release Date : 1994

Biofluid And Tissue Analysis For Drugs Including Hypolipidaemics written by Eric Reid and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.


This book reviews drug development methodology and associated problems with particular reference to the analysis of biofluids and tissues.



The Analysis Of Drugs In Biological Fluids


The Analysis Of Drugs In Biological Fluids
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Author : Joseph Chamberlain
language : en
Publisher: CRC Press
Release Date : 2018-02-06

The Analysis Of Drugs In Biological Fluids written by Joseph Chamberlain and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-06 with Medical categories.


This new edition focuses on a variety of techniques available for the analysis of drugs in biological fluids. Over 150 figures and tables help to describe the latest advances and give examples of their applications. Current chiral analysis methods as well as discussions on the impact of chirality are described. Practical aspects of bioanalytical work, including many examples of laboratory problems not often reported in the scientific literature, are examined in depth.



Bioanalytical Separations


Bioanalytical Separations
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Author :
language : en
Publisher: Elsevier
Release Date : 2003-09-03

Bioanalytical Separations written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-03 with Science categories.


Bioanalytical Separations is volume 4 of the multi-volume series, Handbook of Analytical Separations, providing reviews of analytical separation methods and techniques used for the determination of analytes across a whole range of applications. The theme for this volume is bioanalysis, in this case specifically meaning the analysis of drugs and their metabolites in biological fluids. - Discusses new developments in instrumentation and methods of analyzing drugs and their metabolites in biological fluids - Provides guidance to the different methods, their relative value to the user, and the advantages and pitfalls of their use - Future trends are identified, in terms of the potential impact of new technologies



Nmr Spectroscopy In Drug Development And Analysis


Nmr Spectroscopy In Drug Development And Analysis
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Author : Ulrike Holzgrabe
language : en
Publisher: John Wiley & Sons
Release Date : 2008-07-11

Nmr Spectroscopy In Drug Development And Analysis written by Ulrike Holzgrabe and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-11 with Medical categories.


Since the development of the NMR spectrometer in the 1950s, NMR spectra have been widely used for the elucidation of the 2D structure of newly synthesized and natural compounds. In the 1980s, the high-resolution NMR spectrometer (> 300 Mhz) and 2D experiments were introduced, which opens up the possibility to determine the 3D structure of large molecules, especially biomolecules. However, NMR spectroscopy has been rarely applied to drug analysis. This book illustrates the power and versatility of NMR spectroscopy in the determination of impurities in and the content of drugs, the composition of polymer excipients, the characterization of isomeric drug mixtures, the complexity of drugs with small-size components or ions, and the behavior of drugs in acid and basic solution. In addition, NMR spectroscopy and especially the hyphenated technique with HPLC is shown to be a powerful tool to measure a drug and its metabolites in various body fluids. The solid state NMR technique can give information on the structure, especially the conformation of drugs and excipients in drug formulations. Recently, SAR by NMR, introduced by Fesik, impressively demonstrated the potential of NMR spectroscopy in drug development and in the characterization of the interaction between large molecules and ligands. The complexation between proteins, lipids and cyclodextrins with drugs is described. Finally, NMR imaging (MRI and MRS) can be used to characterize the liberation of drugs from a drug formulation. Furthermore, the distribution of substances in plants, in animals, in tissues and in humans can be visualized by imaging. In short, this book covers all aspects of drug analysis.



Russian Chemical Reviews


Russian Chemical Reviews
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Author :
language : en
Publisher:
Release Date : 1995

Russian Chemical Reviews written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Chemistry categories.




Principles And Practice Of Bioanalysis


Principles And Practice Of Bioanalysis
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Author : Richard F. Venn
language : en
Publisher: CRC Press
Release Date : 2000-06-22

Principles And Practice Of Bioanalysis written by Richard F. Venn and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-06-22 with Medical categories.


Principles and Practice of Bioanalysis provides a guide to the methods available and the techniques currently used in this field. It provides up to the minute information and guidance on the methods and strategy used in developing and running ultra-trace analyses for drugs, metabolites and other substances. The authors writes in an informal and didactic style, offering a logical path through the problems of small molecule (bio)analysis and enables readers to choose appropriate methods of analysis for their needs. Principles and Practice of Bioanalysis provides an overview of analytical methods for analytical scientists within the pharmaceutical industry, research and development, the agrochemical industry, and scientists in the health service, biology and biochemistry. It also gives postgraduate students a useful reference for their research methods.



Mass Spectrometry Bulletin


Mass Spectrometry Bulletin
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Author :
language : en
Publisher:
Release Date : 1995

Mass Spectrometry Bulletin written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Mass spectrometry categories.




Biofluid Assay For Peptide Related And Other Drugs


Biofluid Assay For Peptide Related And Other Drugs
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Author : Eric Reid
language : en
Publisher:
Release Date : 1996

Biofluid Assay For Peptide Related And Other Drugs written by Eric Reid and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Analytical biochemistry categories.


The wide breadth of information covered in this book makes it a vital reference for those involved in drug development and bioanalytical research.



Extraction Methods In Organic Analysis


Extraction Methods In Organic Analysis
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Author : Alan John Handley
language : en
Publisher: Blackwell
Release Date : 1999

Extraction Methods In Organic Analysis written by Alan John Handley and has been published by Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Science categories.


This is the second volume in a new series, Sheffield Analytical Chemistry, which presents the state of the art in chosen sectors of analytical chemistry. In this volume, authors drawn from respected laboratories around the world cover conventional and more recent techniques of extraction and sample preparation - crucial elements in accurate analysis. In recent years, there has been an explosion of interest in new methodologies, fuelled by the need for faster and simpler analysis, but until now there has been no book dedicated to this important area. Each chapter covers some background theory, the available instrumentation and the strengths and weaknesses of the method. Key applications areas are then addressed. This is a book for analytical chemists, organic chemists, environmental scientists, food scientists, pharmaceutical chemists, polymer chemists and earth scientists working in the academic and industrial sectors.



Drug Development Assay Approaches Including Molecular Imprinting And Biomarkers


Drug Development Assay Approaches Including Molecular Imprinting And Biomarkers
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Author : Eric Reid
language : en
Publisher: Royal Society of Chemistry
Release Date : 1998

Drug Development Assay Approaches Including Molecular Imprinting And Biomarkers written by Eric Reid and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.


A book vital to libraries, laboratory and industrial staff of research and professional organisations involved in drug development and bioanalytical research.