Bioinformatics Of Non Coding Rnas With Applications To Biomedicine Recent Advances And Open Challenges
DOWNLOAD
Download Bioinformatics Of Non Coding Rnas With Applications To Biomedicine Recent Advances And Open Challenges PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Bioinformatics Of Non Coding Rnas With Applications To Biomedicine Recent Advances And Open Challenges book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Bioinformatics Of Non Coding Rnas With Applications To Biomedicine Recent Advances And Open Challenges
DOWNLOAD
Author : Carlo Maria Croce
language : en
Publisher: Frontiers Media SA
Release Date : 2017-01-27
Bioinformatics Of Non Coding Rnas With Applications To Biomedicine Recent Advances And Open Challenges written by Carlo Maria Croce and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-27 with categories.
The recent discovery of small and long non-coding RNAs (ncRNAs) has represented a major breakthrough in the life sciences. These molecules add a new layer of complexity to biological processes and pathways by revealing a sophisticated and dynamic interconnected system whose structure is just beginning to be uncovered. Genetic and epigenetic aberrations affecting ncRNA gene sequences and their expression have been linked to a variety of pathological conditions, including cancer, cardiovascular and neurological diseases. Latest advances in the development of high throughput analysis techniques may help to shed light on the complex regulatory mechanisms in which ncRNA molecules are involved. Bioinformatics tools constitute a unique and essential resource for non-coding RNA studies, providing a powerful technology to organize, integrate and analyze the huge amount of data produced daily by wet biology experiments in order to discover patterns, identify relationships among heterogeneous biological elements and formulate functional hypotheses. This Research Topic reviews current knowledge, introduces novel methods, and discusses open challenges of this exciting and innovative field in connection with the most important biomedical applications. It consists of four reviews and six original research and methods articles, spanning the full scope of the Research Topic.
Rna Seq Analysis Methods Applications And Challenges
DOWNLOAD
Author : Filippo Geraci
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-08
Rna Seq Analysis Methods Applications And Challenges written by Filippo Geraci and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-08 with categories.
A Comprehensive Guide Through The Italian Database Research Over The Last 25 Years
DOWNLOAD
Author : Sergio Flesca
language : en
Publisher: Springer
Release Date : 2017-05-29
A Comprehensive Guide Through The Italian Database Research Over The Last 25 Years written by Sergio Flesca and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-29 with Technology & Engineering categories.
This book offers readers a comprehensive guide to the evolution of the database field from its earliest stages up to the present—and from classical relational database management systems to the current Big Data metaphor. In particular, it gathers the most significant research from the Italian database community that had relevant intersections with international projects. Big Data technology is currently dominating both the market and research. The book provides readers with a broad overview of key research efforts in modelling, querying and analysing data, which, over the last few decades, have became massive and heterogeneous areas.
Rna Technologies And Their Applications
DOWNLOAD
Author : Volker A. Erdmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-02
Rna Technologies And Their Applications written by Volker A. Erdmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-02 with Science categories.
RNA technologies are the driving forces of modern medicine and biotechnology. They combine the fields of biochemistry, chemistry, molecular biology, cell biology, physics, nanotechnology and bioinformatics. The combination of these topics is set to revolutionize the medicine of tomorrow. After more than 15 years of extensive research in the field of RNA technologies, the first therapeutics are ready to reach the first patients. Thus we are witnessing the birth of a very exciting time in the development of molecular medicine, which will be based on the methods of RNA technologies. This volume is the first of a series. It covers various aspects of RNA interference and microRNAs, although antisense RNA applications, hammerhead ribozyme structure and function as well as non-coding RNAs are also discussed. The authors are internationally highly respected experts in the field of RNA technologies.
Non Coding Rnas
DOWNLOAD
Author : Lütfi Tutar
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-03-04
Non Coding Rnas written by Lütfi Tutar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-04 with Medical categories.
Noncoding RNAs (ncRNAs) are an attractive research field in the RNA world. ncRNAs play important roles in regulating gene expression in animals, plants, and various human diseases. It is clear that current and further research on ncRNAs will change our knowledge of the nature of genome composition by editing previous dogmas. This book provides an overview of current knowledge on ncRNA research by dealing with miRNA and ncRNA-related human diseases, plant miRNA markers, and the roles of lncRNAs in cancer and epigenetics.
Micrornas
DOWNLOAD
Author : Krishnarao Appasani
language : en
Publisher: Cambridge University Press
Release Date : 2009-08-20
Micrornas written by Krishnarao Appasani and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-20 with Science categories.
MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their recent discovery is revolutionising both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development. Forewords by: Sidney Altman, Yale University, Winner of the Nobel Prize in Chemistry, 1989 and Victor R. Ambros, Dartmouth Medical School, Co-discoverer of MicroRNAs
Single Cell Biomedicine
DOWNLOAD
Author : Jianqin Gu
language : en
Publisher: Springer
Release Date : 2018-06-25
Single Cell Biomedicine written by Jianqin Gu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-25 with Science categories.
The book focuses on various detection targets applied in single cell studies, including tumor tissue cells, circulating tumor cells (CTCs), disseminated tumor cells (DTCs), circulating tumor DNA (ctDNA), cell-free DNA (cfDNA) and cancer stem cells (CSCs). It also discusses and compares detection methods using these detection targets in different fields to reveal single cell biomedical functions. The volume focuses not only on the methods already been established and validated, and also the methods newly developed. The book also highlights the importance and potential of single cell biomedicine in the development and validation of precision medicine strategies. It is useful for researchers and students in the field of cell biology, molecular medicine and precision medicine etc.
Applications Of Rna Seq And Omics Strategies
DOWNLOAD
Author : Fabio Marchi
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-09-13
Applications Of Rna Seq And Omics Strategies written by Fabio Marchi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-13 with Medical categories.
The large potential of RNA sequencing and other "omics" techniques has contributed to the production of a huge amount of data pursuing to answer many different questions that surround the science's great unknowns. This book presents an overview about powerful and cost-efficient methods for a comprehensive analysis of RNA-Seq data, introducing and revising advanced concepts in data analysis using the most current algorithms. A holistic view about the entire context where transcriptome is inserted is also discussed here encompassing biological areas with remarkable technological advances in the study of systems biology, from microorganisms to precision medicine.
Evolution Of Translational Omics
DOWNLOAD
Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2012-09-13
Evolution Of Translational Omics written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-13 with Science categories.
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
Bioinformatics And Human Genomics Research
DOWNLOAD
Author : Diego A. Forero
language : en
Publisher: CRC Press
Release Date : 2021-12-22
Bioinformatics And Human Genomics Research written by Diego A. Forero and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-22 with Science categories.
Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.