Bioinformatics Of Non Small Cell Lung Cancer And The Ras Proto Oncogene

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Bioinformatics Of Non Small Cell Lung Cancer And The Ras Proto Oncogene
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Author : Amita Kashyap
language : en
Publisher: Springer
Release Date : 2014-09-08
Bioinformatics Of Non Small Cell Lung Cancer And The Ras Proto Oncogene written by Amita Kashyap and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-08 with Technology & Engineering categories.
Cancer is initiated by activation of oncogenes or inactivation of tumor suppressor genes. Mutations in the K-ras proto-oncogene are responsible for 10–30% of adenocarcinomas. Clinical Findings point to a wide variety of other cancers contributing to lung cancer incidence. Such a scenario makes identification of lung cancer difficult and thus identifying its mechanisms can contribute to the society. Identifying unique conserved patterns common to contributing proto-oncogenes may further be a boon to Pharmacogenomics and pharmacoinformatics. This calls for ab initio/de novo drug discovery that in turn will require a comprehensive in silico approach of Sequence, Domain, Phylogenetic and Structural analysis of the receptors, ligand screening and optimization and detailed Docking studies. This brief involves extensive role of the RAS subfamily that includes a set of proteins, which cause an over expression of cancer-causing genes like M-ras and initiate tumour formation in lungs. SNP Studies and Structure based drug discovery will also be undertaken.
Bioinformatics Of Non Small Cell Lung Cancer And The Ras Proto Oncogene
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Author : Amita Kashyap
language : en
Publisher:
Release Date : 2014-09-30
Bioinformatics Of Non Small Cell Lung Cancer And The Ras Proto Oncogene written by Amita Kashyap and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-30 with categories.
Biochemistry And Molecular Biology Compendium
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Author : Roger L. Lundblad
language : en
Publisher: CRC Press
Release Date : 2019-11-11
Biochemistry And Molecular Biology Compendium written by Roger L. Lundblad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-11 with Medical categories.
This book is an accessible resource offering practical information not found in more database-oriented resources. The first chapter lists acronyms with definitions, and a glossary of terms and subjects used in biochemistry, molecular biology, biotechnology, proteomics, genomics, and systems biology. There follows chapters on chemicals employed in biochemistry and molecular biology, complete with properties and structure drawings. Researchers will find this book to be a valuable tool that will save them time, as well as provide essential links to the roots of their science. Key selling features: Contains an extensive list of commonly used acronyms with definitions Offers a highly readable glossary for systems and techniques Provides comprehensive information for the validation of biotechnology assays and manufacturing processes Includes a list of Log P values, water solubility, and molecular weight for selected chemicals Gives a detailed listing of protease inhibitors and cocktails, as well as a list of buffers
Computational Intelligence Techniques In Diagnosis Of Brain Diseases
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Author : Sasikumar Gurumoorthy
language : en
Publisher: Springer
Release Date : 2017-09-05
Computational Intelligence Techniques In Diagnosis Of Brain Diseases written by Sasikumar Gurumoorthy and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-05 with Technology & Engineering categories.
This book highlights a new biomedical signal processing method of extracting a specific underlying signal from possibly noisy multi-channel recordings, and shows that the method is suitable for extracting independent components from the measured electroencephalogram (EEG) signal. The system efficiently extracts memory spindles and is also effective in Alzheimer seizures. Current developments in computer hardware and signal processing have made it possible for EEG signals or “brain waves” to communicate between humans and computers – an area that can be extended for use in this domain.
Computational Genomics And Structural Bioinformatics In Personalized Medicines Volume Ii
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Author : George Priya Doss C
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-06
Computational Genomics And Structural Bioinformatics In Personalized Medicines Volume Ii written by George Priya Doss C and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-06 with Medical categories.
Women In Cancer Molecular Targets And Therapeutics Volume Ii 2022
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Author : Cinzia Lanzi
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-26
Women In Cancer Molecular Targets And Therapeutics Volume Ii 2022 written by Cinzia Lanzi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-26 with Medical categories.
Cancer Systems Biology Bioinformatics And Medicine
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Author : Alfredo Cesario
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-08-21
Cancer Systems Biology Bioinformatics And Medicine written by Alfredo Cesario and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-21 with Medical categories.
This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.
Advanced Ai Techniques And Applications In Bioinformatics
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Author : Loveleen Gaur
language : en
Publisher: CRC Press
Release Date : 2021-10-17
Advanced Ai Techniques And Applications In Bioinformatics written by Loveleen Gaur and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-17 with Technology & Engineering categories.
The advanced AI techniques are essential for resolving various problematic aspects emerging in the field of bioinformatics. This book covers the recent approaches in artificial intelligence and machine learning methods and their applications in Genome and Gene editing, cancer drug discovery classification, and the protein folding algorithms among others. Deep learning, which is widely used in image processing, is also applicable in bioinformatics as one of the most popular artificial intelligence approaches. The wide range of applications discussed in this book are an indispensable resource for computer scientists, engineers, biologists, mathematicians, physicians, and medical informaticists. Features: Focusses on the cross-disciplinary relation between computer science and biology and the role of machine learning methods in resolving complex problems in bioinformatics Provides a comprehensive and balanced blend of topics and applications using various advanced algorithms Presents cutting-edge research methodologies in the area of AI methods when applied to bioinformatics and innovative solutions Discusses the AI/ML techniques, their use, and their potential for use in common and future bioinformatics applications Includes recent achievements in AI and bioinformatics contributed by a global team of researchers
Machine Learning For Biological Sequence Analysis
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Author : Quan Zou
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-09
Machine Learning For Biological Sequence Analysis written by Quan Zou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-09 with Science categories.
Bioinformatics Analysis Of Single Cell Sequencing Data And Applications In Precision Medicine
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Author : Jialiang Yang
language : en
Publisher: Frontiers Media SA
Release Date : 2020-02-27
Bioinformatics Analysis Of Single Cell Sequencing Data And Applications In Precision Medicine written by Jialiang Yang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-27 with categories.