Biological Macromolecular Dynamics

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Dynamics And The Problem Of Recognition In Biological Macromolecules

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Author : Oleg Jardetzky
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Dynamics And The Problem Of Recognition In Biological Macromolecules written by Oleg Jardetzky and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

From within complex structures of organisms and cells down to the molecular level, biological processes all involve movement. Muscular fibers slide on each other to activate the muscle, as polymerases do along nucleic acids for replicating and transcribing the genetic material. Cells move and organize themselves into organs by recognizing each other through macromolecular surface-specific interactions. These recognition processes involve the mu tual adaptation of structures that rely on their flexibility. All sorts of conformational changes occur in proteins involved in through-membrane signal transmission, showing another aspect of the flexibility of these macromolecules. The movement and flexibility are inscribed in the polymeric nature of essential biological macromolecules such as proteins and nucleic acids. For instance, the well-defined structures formed by the long protein chain are held together by weak noncovalent interac tions that design a complex potential well in which the protein floats, permanently fluctuating between several micro- or macroconformations in a wide range of frequencies and ampli tudes. The inherent mobility of biomolecular edifices may be crucial to the adaptation of their structures to particular functions. Progress in methods for investigating macromolecular structures and dynamics make this hypothesis not only attractive but more and more testable.

Nuclear Magnetic Resonance Of Biological Macromolecules Part B

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Author :
language : en
Publisher: Elsevier
Release Date : 2001-07-12

Nuclear Magnetic Resonance Of Biological Macromolecules Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-12 with Science categories.

This volume and its companion, Volume 338, supplement Volumes 176, 177, 239, and 261. Chapters are written with a "hands-on" perspective. That is, practical applications with critical evaluations of methodologies and experimental considerations needed to design, execute, and interpret NMR experiments pertinent to biological molecules.

Water And Biological Macromolecules

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Author : Westhof
language : en
Publisher: CRC Press
Release Date : 1993-08-16

Water And Biological Macromolecules written by Westhof and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-08-16 with Science categories.

Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists.

Molecular Dynamics

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Author : Lichang Wang
language : en
Publisher: IntechOpen
Release Date : 2012-04-11

Molecular Dynamics written by Lichang Wang and has been published by IntechOpen this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-11 with Computers categories.

Molecular Dynamics is a two-volume compendium of the ever-growing applications of molecular dynamics simulations to solve a wider range of scientific and engineering challenges. The contents illustrate the rapid progress on molecular dynamics simulations in many fields of science and technology, such as nanotechnology, energy research, and biology, due to the advances of new dynamics theories and the extraordinary power of today's computers. This second book begins with an introduction of molecular dynamics simulations to macromolecules and then illustrates the computer experiments using molecular dynamics simulations in the studies of synthetic and biological macromolecules, plasmas, and nanomachines. Coverage of this book includes: Complex formation and dynamics of polymers Dynamics of lipid bilayers, peptides, DNA, RNA, and proteins Complex liquids and plasmas Dynamics of molecules on surfaces Nanofluidics and nanomachines

Dynamics Of Biological Macromolecules By Neutron Scattering

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Author : Salvatore Magazù
language : en
Publisher: Bentham Science Publishers
Release Date : 2011

Dynamics Of Biological Macromolecules By Neutron Scattering written by Salvatore Magazù and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.

Dynamics of Biological Macromolecules by Neutron Scattering provides insight into the study of the dynamics of biological macromolecules by neutron scattering techniques. The applicability of neutron scattering to expanding fields of biological studies is

Molecular Dynamics

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Author : Lichang Wang
language : en
Publisher: IntechOpen
Release Date : 2012-04-11

Molecular Dynamics written by Lichang Wang and has been published by IntechOpen this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-11 with Computers categories.

Molecular Dynamics is a two-volume compendium of the ever-growing applications of molecular dynamics simulations to solve a wider range of scientific and engineering challenges. The contents illustrate the rapid progress on molecular dynamics simulations in many fields of science and technology, such as nanotechnology, energy research, and biology, due to the advances of new dynamics theories and the extraordinary power of today's computers. This second book begins with an introduction of molecular dynamics simulations to macromolecules and then illustrates the computer experiments using molecular dynamics simulations in the studies of synthetic and biological macromolecules, plasmas, and nanomachines. Coverage of this book includes: Complex formation and dynamics of polymers Dynamics of lipid bilayers, peptides, DNA, RNA, and proteins Complex liquids and plasmas Dynamics of molecules on surfaces Nanofluidics and nanomachines

Biological Macromolecular Dynamics

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Author : Stephen Cusack
language : en
Publisher:
Release Date : 1997

Biological Macromolecular Dynamics written by Stephen Cusack and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Science categories.

Biomedical Index To Phs Supported Research Pt A Subject Access A H

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Author :
language : en
Publisher:
Release Date : 1992

Biomedical Index To Phs Supported Research Pt A Subject Access A H written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medicine categories.

Macromolecular Crystallography

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Author : Maria Armenia Carrondo
language : en
Publisher: Springer
Release Date : 2011-12-01

Macromolecular Crystallography written by Maria Armenia Carrondo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-01 with Science categories.

This volume is a collection of the contributions presented at the 42nd Erice Crystallographic Course whose main objective was to train the younger generation on advanced methods and techniques for examining structural and dynamic aspects of biological macromolecules. The papers review the techniques used to study protein assemblies and their dynamics, including X-ray diffraction and scattering, electron cryo-electron microscopy, electro nanospray mass spectrometry, NMR, protein docking and molecular dynamics. A key theme throughout the book is the dependence of modern structural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future.

Dynamics Structure And Function Of Biological Macromolecules

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Author : Oleg Jardetzky
language : en
Publisher: IOS Press
Release Date : 2001

Dynamics Structure And Function Of Biological Macromolecules written by Oleg Jardetzky and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Science categories.

A collection of articles looking at modern structural biology, summarizing the applications of physical methods - such as x-ray diffraction, high resolution nuclear magnetic resonance and molecular dynamics - to the study of protein structure and dynamics. There is a review of contemporary thoughts within the field, looking at the mechanisms of alloateric transitions and allosteric control, the transmission of information within protein structures and the role of dynamics in determining the specificity of protein - ligand interactions. There is also a look at future innovations.