Biology And Management Of Lung Cancer


Biology And Management Of Lung Cancer
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Biology And Management Of Lung Cancer


Biology And Management Of Lung Cancer
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Author : F. Anthony Greco
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Biology And Management Of Lung Cancer written by F. Anthony Greco and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Lung cancer remains an extremely difficult neoplasm to treat effectively. A large part of our lack of success in dealing with these patients is related to our empiric therapeutic attempts. Slowly our basic understanding of the lung cancers is improving and techniques are becoming available to allow us to better understand the biology of these neoplasms. This volume reviews several areas of interest in regard to the biologic behavior and characteris of lung cancer. tics Chapters deal with the in vitro growth of small cell lung cancer, the inves tigation of growth factors in human lung cancer, the production of mono clonal antibodies against lung cancer and the application and potential use fulness of the human tumor cloning assay in lung cancer management. These avenues of investigation are likely to establish a more scientific basis on which more rational therapy can be designed. Carney and associates have established several continuous small cell lung cancer cell lines in their laboratory. The amine precursor uptake and decar boxylation (APUD) properties of this neoplasm have been confirmed by demonstrating the presence of neurosecretory granules and high levels of the APUD enzyme L-dopa decarboxylase. In addition, several new markers have been documented including bombesin, creatine-kinase BB and neuron specific enolase. These tumor products along with others may be useful serum markers in patients with small cell lung cancer.



Biology And Management Of Lung Cancer


Biology And Management Of Lung Cancer
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Author : F Anthony Greco
language : en
Publisher:
Release Date : 1983-03-31

Biology And Management Of Lung Cancer written by F Anthony Greco and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-03-31 with categories.




Tumors Of The Chest


Tumors Of The Chest
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Author : Konstantinos N. Syrigos
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-10-06

Tumors Of The Chest written by Konstantinos N. Syrigos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-06 with Medical categories.


The purpose of this textbook is to meticulously depict all aspects of chest tumors in a comprehensive volume format that encompasses their biology, clinical presentation and management. It is the only book to do this. Chapters of specific interest have also been included to cover such wide-ranging topics as management of the elderly and chemoprevention, along with ethical, social and financial issues associated with such tumors. All participating authors, selected from an international panel of highly regarded scientists currently pioneering lung cancer research, are major contributors in the area of expertise they have been chosen to present.



Biology Of Lung Cancer


Biology Of Lung Cancer
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Author : Steven T. Rosen
language : en
Publisher: CRC Press
Release Date : 1988-08-19

Biology Of Lung Cancer written by Steven T. Rosen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-08-19 with Medical categories.




Lung Cancer Metastasis


Lung Cancer Metastasis
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Author : Venkateshwar Keshamouni
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-09-18

Lung Cancer Metastasis written by Venkateshwar Keshamouni and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-18 with Medical categories.


Lung cancer is the leading cause of cancer-related mortality. Metastatic lung cancer is responsible for more than ninety percent of lung cancer related deaths. However, relatively little progress has been made in understanding the process of lung cancer metastasis. The two main aims of this book are a) to introduce clinical aspects to basic scientists and basic molecular and cellular concepts to clinical investigators, in order to promote collaboration and foster much needed translational research; and b) to introduce new and emerging concepts and approaches in metastasis research to lung cancer research community at large. In this attempt, the book will cover a broad spectrum of subjects ranging from the current trends in the clinical management of the metastatic disease, to the systems biology approach for gaining insights into the mechanisms of metastasis. Some of the subjects covered will include: defining basic hallmarks of a metastatic cell, the concept of tumor stem cells, epithelial-mesenchymal transitions, evasion of immune-surveillance, tumor-stromal interactions, angiogenesis, molecular imaging and biomarker discovery.



Cancer Biology And Management


Cancer Biology And Management
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Author : C. J. Williams
language : en
Publisher:
Release Date : 1990-01-05

Cancer Biology And Management written by C. J. Williams and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-01-05 with Medical categories.


This introduction to cancer medicine covers aetiology, investigation, diagnosis, management and treatment, setting it apart from other books, which usually consider only one discipline. Although comprehensive in scope, the book is written in a lively style and at an introductory level that will appeal to students and junior doctors. It covers the principles of cancer biology, the causes of cancer, and cancer investigations and manifestations. Emphasizing the practical care of the cancer patient throughout, the book provides a rational framework of principles for the management of tumors. The individual tumors themselves are discussed in the second part of the book, which also includes summaries of the main forms of treatment: surgery, radiotherapy, and chemotherapy.



Cancer Of The Lung


Cancer Of The Lung
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Author : Alan Weitberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-10-04

Cancer Of The Lung written by Alan Weitberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-04 with Medical categories.


Alan B. Weitberg, MD, and a panel of internationally recognized basic scientists and clinicians present a comprehensive discussion of lung cancer, including a practice-oriented review of its diagnosis, evaluation, and treatment. The contributors offer not only an understandable description of its molecular origins-an essential key to developing future therapies and preventive measures-but also rigorously discuss well-tested approaches, as well as those that are currently being evaluated for future use in both the laboratory and clinic. The book also elucidates the creation and effective deployment of treatment guidelines introduced by third party payers to improve clinical outcomes, even while lowering healthcare costs.



Biology Of Lung Cancer


Biology Of Lung Cancer
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Author : Madelein Kane
language : en
Publisher: CRC Press
Release Date : 1998-08-27

Biology Of Lung Cancer written by Madelein Kane and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-08-27 with Medical categories.


These questions and more, are answered by a distinguished team of nearly 40 specialists in the field who present the latest epidemiological, genetic, molecular, cellular, and diagnostic research findings in lung cancer research and their applications in patient management. Biology of Lung Cancer discusses available in vivo and in vitro models and their appropriate uses in specific studies highlights recent research on mechanisms of lung cancer in addition to potential future patient management targets explores mechanisms of resistance to treatment and reveals current and developing strategies in chemotherapy and gene therapy shows how novel data on the progression of premalignant molecular and cellular properties can be applied towards early definitive diagnosis considers the inheritance of genes that play pivotal roles in carcinogen activation and deactivation and more! Complemented with nearly 2500 bibliographic citations, drawings, photographs, and x-rays, this landmark reference is fundamental reading for pulmonologists, oncologists, physiologists, pathologists, cancer researchers, cardiothoracic surgeons, pharmacologists, biochemists, biophysicists, geneticists, epidemiologists, radiation oncologists, neurobiologists, and graduate and medical school students in these disciplines.



Lung Cancer


Lung Cancer
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Author : Anne C. Chiang
language : en
Publisher: Springer Nature
Release Date : 2021-09-30

Lung Cancer written by Anne C. Chiang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-30 with Medical categories.


Lung cancer has seen a paradigm shift in disease treatment over the past few years, with major changes in the therapeutic drugs now available as well as in the overall management approach. For targeted and immunotherapeutic approaches, understanding the biology of acquired resistance is a key strategy that has yielded productive advances in the subsequent treatment. Future advances also include incorporating biomarker data obtained from solid and liquid biopsies, as well as combination of immunotherapy with radiotherapy and in special populations such patients with CNS involvement.



Lung Cancer


Lung Cancer
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Author : David J. Stewart
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-10

Lung Cancer written by David J. Stewart and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-10 with Medical categories.


Defining the Lung Cancer Problem 1 Lung cancer is the leading cause of cancer death in the world. It kills almost as many Americans as cancers of the breast, prostate, colon, rectum, pancreas, and 2 kidney combined, and accounts for 28.6% of all US cancer deaths. With an increase in the 5-year relative survival rate from 13% to only 16% in the more than 2 30 years from 1974 to the present, it will take us another 840 years to eradicate lung cancer deaths if we do not improve the current rate of progress. As discussed in this text, lung cancer prevention has received substantial att- tion. The decrease in smoking in recent decades has helped, but smoking is not the only problem. Lung cancer in people who have never smoked is currently the 5th 3 leading cause of cancer death in the United States. Several factors contribute to the lethality of lung cancer, including the rapidity of tumor growth, advanced stage at diagnosis (due to nonspecificity of early sy- toms and the uncertain efficacy of screening), early development of metastases, and resistance to therapy. Several chapters in this book discuss new molecular targets that may be potentially exploitable in the future, as well as discussing our track record to date in exploiting them.