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Biology Of Radiation Carcinogenesis


Biology Of Radiation Carcinogenesis
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Biology Of Radiation Carcinogenesis


Biology Of Radiation Carcinogenesis
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Author : John M. Yuhas
language : en
Publisher:
Release Date :

Biology Of Radiation Carcinogenesis written by John M. Yuhas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Aging Carcinogenesis And Radiation Biology


Aging Carcinogenesis And Radiation Biology
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Author : Kendric Smith
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Aging Carcinogenesis And Radiation Biology written by Kendric Smith and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.


The covalent attachment to deoxyribonucleic acid in vivo of a large number of different types of chemical compounds (both normal cellular constituents such as proteins and amino acids, and also exogenous compounds such as drugs, carcinogens, etc. ) have been shown to exert profound effects upon cells. Four research activi ties, formerly considered to be totally independent, relate to this problem of nucleic acid adducts--(1) normal covalent attachment of DNA to membranes, protein linkers in chromosomes, etc. ; (2) the roles of radiation and chemical enhancement of DNA adduct formation in cell killing and mutagenesis. (A related field is the use of known cross-linking reactions to gain information on structural associations in macromolecular complexes. ); (3) the relevance of DNA adducts to chemical and radiation carcinogenesis; (4) the rele vance of DNA adducts to the cross-linking theory of cellular aging. (1) There are numerous examples of normal linkages between DNA and protein, e. g. , DNA-membrane attachment sites, protein linkers in chromosomes, amino acids covalently linked to DNA as a function of growth conditions, and gene regulation by non-covalently bound proteins. A summary of data on natural adducts to DNA thus serves to introduce the subject of the radiation and chemical enhancement of DNA adduct formation. (2) In the past, radiation biology has been concerned mainly with trying to understand the radiation chemistry of purified DNA, and the biological effects and repair of these radiation-induced alterations when produced in cellular DNA.



Radiation Carcinogenesis


Radiation Carcinogenesis
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Author : Arthur C. Upton
language : en
Publisher: Elsevier Publishing Company
Release Date : 1986

Radiation Carcinogenesis written by Arthur C. Upton and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.


This book provides the first comprehensive and systematic survey of present knowledge about radiation carcinogenesis. World experts review in detail current information on such topics as the incidence of various forms of cancer in irradiated populations, the carcinogenic effects of ionizing radiation in laboratory animals, theoretical mechanisms of radiation carcinogenesis, and the implications of the data for assessing the risks of human cancer. In view of recent controversy about the carcinogenic hazards of low-level exposure to radiation and other carcinogens, this book is a timely contribution toward our understanding of the carcinogenic risks of low-level radiation.



Advances In Radiation Biology


Advances In Radiation Biology
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Author : John T. Lett
language : en
Publisher: Academic Press
Release Date : 2013-10-22

Advances In Radiation Biology written by John T. Lett and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.


Advances in Radiation Biology, Volume 9, provides an overview of the state of knowledge in radiation biology. The book contains nine chapters and begins with a study on the ways in which physical and chemical agents might trigger "regulatory dysfunction" and how these agents might interact with each other. This is followed by separate chapters on the mechanisms underlying changes in vascular function after doses of radiation in the therapeutic range and their role in the development of late effects in normal tissues; the future of hypoxic cell sensitizers in the clinical setting; DNA strand break formation by ionizing radiation; and major pathways which result in radiation-induced loss of cellular proliferative capacity. Subsequent chapters deal with the solid-state radiation chemistry of DNA; radiosensitivity of proliferating mammalian cells; the use of microwave/radiofrequency energy cancer treatment; and the decline of basic radiobiology.



Radiation Biology And Cancer


Radiation Biology And Cancer
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Author :
language : en
Publisher:
Release Date : 1959

Radiation Biology And Cancer written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1959 with Cancer categories.




Effects Of Low Dose And Low Dose Rate Radiation


Effects Of Low Dose And Low Dose Rate Radiation
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Author : Oddvar F. Nygaard
language : en
Publisher: Academic Press
Release Date : 2013-10-22

Effects Of Low Dose And Low Dose Rate Radiation written by Oddvar F. Nygaard and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.


Advances in Radiation Biology, Volume 6: Effects of Low Dose and Low Dose Rate Radiation examines the biological effects of low dose and low dose rate ionizing radiation on a broad scale, covering various articles from microdosimetry to analyses of human responses. Estimates of the effects on humans from low doses or from sustained exposures to low dose rates of ionizing radiations are of critical importance for the assessment of radiation risks under occupational and environmental conditions. This book consists of such knowledge that is essential for radiation protection and governmental regulatory activities pertaining to radiation exposure. This volume is intended for radiobiologists, radiation epidemiologists, radiation physicists, radiation safety personnel, health officials, and individuals involved in regulatory activities.



Radiobiology Self Assessment Guide


Radiobiology Self Assessment Guide
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Author : Jennifer Yu, MD, PhD
language : en
Publisher: Springer Publishing Company
Release Date : 2016-11-03

Radiobiology Self Assessment Guide written by Jennifer Yu, MD, PhD and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-03 with Medical categories.


Radiobiology Self-Assessment Guide--a companion to the Radiation Oncology Self-Assessment Guide and Physics in Radiation Oncology Self-Assessment Guide--is a comprehensive review for practitioners of radiation oncology looking to enhance their knowledge of radiobiology. It covers in depth the principles of radiobiology as applied to radiation oncology along with their clinical applications. To foster retention of key concepts and data, the resource utilizes a user-friendly "flash card" question and answer format with over 700 questions. The questions are supported by detailed answers and rationales along with reference citations for source information. The guide is comprised of 29 chapters and cover topics commonly found on the radiation and cancer biology portion of the radiation oncology board examination. Aspects of basic radiobiology covered include fundamentals such as cell cycle, cell survival curves and interactions of radiation with matter, and acute and long-term sequelae of radiation. Modern concepts such as immunotherapy, radiogenomics, and normal and cancer stem cells are also included. Focused and authoritative, this must-have review provides the expertise of faculty from the Department of Radiation Oncology at the Cleveland Clinic Taussig Cancer Institute and Lerner Research Institute. Key Features: Provides a comprehensive study guide for the Radiation and Cancer Biology portion to the Radiation Oncology Board Exam Includes more than 700 questions with detailed answers and rationales on flip pages for easy, flash card-like review Includes essential review of cancer biology concepts such as immunotherapy, stem cells, gene therapy, chemotherapy and targeted agents Content provided by a vast array of contributors, including attending radiation oncology physicians, physicists, and radiation oncology residents



Aging Carcinogenesis And Radiation Biology


Aging Carcinogenesis And Radiation Biology
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Author : Kendric Smith
language : en
Publisher:
Release Date : 2014-01-15

Aging Carcinogenesis And Radiation Biology written by Kendric Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.




Icrp Publication 131


Icrp Publication 131
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Author : ICRP,
language : en
Publisher: SAGE Publications Limited
Release Date : 2016-01-05

Icrp Publication 131 written by ICRP, and has been published by SAGE Publications Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-05 with Science categories.


This report provides a review of stem cells/progenitor cells and their responses to ionising radiation in relation to issues relevant to stochastic effects of radiation which form a major part of the ICRP system of radiological protection. Current information on stem cell characteristics, maintenance and renewal, evolution with age, location in stem cell “niches”, radiosensitivity to acute and protracted exposures, is presented in a series of substantial reviews as Annexes concerning haematopoietic tissue, mammary gland, thyroid, digestive tract, lung, skin and bone. This foundation of knowledge of stem cells is used in the main text of the report to provide a biological insight to issues such as the linear-no-threshold (LNT) model, cancer risk among tissues, dose-rate effects and changes in the risk of radiation carcinogenesis by age at exposure and attained age.



Current Cancer Research On Radiation Carcinogenesis And Related Radiobiology


Current Cancer Research On Radiation Carcinogenesis And Related Radiobiology
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Author :
language : en
Publisher:
Release Date : 1981

Current Cancer Research On Radiation Carcinogenesis And Related Radiobiology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Carcinogenesis categories.