Biology Of The Mouse Histocompatibility 2 Complex
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Biology Of The Mouse Histocompatibility 2 Complex
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Author : J. de Klein
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biology Of The Mouse Histocompatibility 2 Complex written by J. de Klein and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Somewhere I heard a story of a bridge and a painter. The bridge was enormous and was made all of metal, and the painter's job was to keep it from rusting. He would start at one end and slowly proceed, day by day, month by month, toward the other end, painting the bridge. But no sooner would he finish with the painting than the bridge would begin to rust again. The rust, too, would start at one end and slowly proceed toward the other end, systematically destroying the painter's endeavor. And so the painter would return to where he had started, and begin painting again, slowly proceeding toward the other end of the bridge, always just one step ahead of the rust. And if the story is true, the painter might still be painting that bridge-a modern Sisyphus! During the writing of this book, the story of the painter and his bridge kept coming to mind. The field the book covers has been developing so rapidly that, like the painter, I too had to return to where I had started and fight the rust of obsolescence. But unlike the painter, I had a deadline to meet, which constituted a point of no return. And so, sending off this manuscript, I have no choice but to watch the fruits of my endeavor be overtaken by the rust.
Biology Of Mouse Histocompatibility 2 Complex
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Author : J. Klein
language : en
Publisher:
Release Date : 1971
Biology Of Mouse Histocompatibility 2 Complex written by J. Klein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with categories.
Biology Of The Mouse Histocompatibility 2 Complex Of Immunogenetics Applied To A Single System
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Author : Jan Klein
language : en
Publisher:
Release Date : 1975
Biology Of The Mouse Histocompatibility 2 Complex Of Immunogenetics Applied To A Single System written by Jan Klein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with categories.
Cell Biology Of The Major Histocompatibility Complex
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Author : Benvenuto Pernis
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Cell Biology Of The Major Histocompatibility Complex written by Benvenuto Pernis and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Health & Fitness categories.
Cell Biology of the Major Histocompatibility Complex documents the proceedings of a symposium on ""Cell Biology of the Major Histocompatibility Complex"" held at Arden House on the Harriman Campus of Columbia University from June 8 -10, 1984. The meeting was the ninth of the P & S Biomedical Sciences Symposia. The book is organized into five parts. Part I on the structure of MHC molecules includes papers on human histocompatibility antigens; the cloning of human MHC; and organization of the genes of the H-2 complex. Part II on alternate forms of MHC molecules includes studies on the expression of a secreted form of the MHC class I antigen and alternative splicing in the H-2 multigene family. Part III deals with MHC biosynthesis, intracellular transport, and membrane expression. It includes studies on the manipulation of glycans on antigens of the MHC and dynamics of MHC molecules in lymphoid cells. Part IV on homologues of class I MHC molecules covers topics such as Tla expression in normal and malignant cells and the Qa series of antigens. Part V on the association of MHC with antigens includes studies such as histocompatibility molecules as immune response gene products and molecular nature of T-cell recognition of antigen.
Janeway S Immunobiology
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Author : Kenneth Murphy
language : en
Publisher: Garland Science
Release Date : 2010-06-22
Janeway S Immunobiology written by Kenneth Murphy and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Medical categories.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Evolution Of The House Mouse
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Author : Miloš Macholán
language : en
Publisher: Cambridge University Press
Release Date : 2012-07-19
Evolution Of The House Mouse written by Miloš Macholán and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-19 with Science categories.
The house mouse is the source of almost all genetic variation in laboratory mice; its genome was sequenced alongside that of humans, and it has become the model for mammalian speciation. Featuring contributions from leaders in the field, this volume provides the evolutionary context necessary to interpret these patterns and processes in the age of genomics. The topics reviewed include mouse phylogeny, phylogeography, origins of commensalism, adaptation, and dynamics of secondary contacts between subspecies. Explorations of mouse behaviour cover the nature of chemical and ultrasonic signalling, recognition, and social environment. The importance of the mouse as an evolutionary model is highlighted in reviews of the first described example of meiotic drive (t-haplotype) and the first identified mammalian speciation gene (Prdm9). This detailed overview of house mouse evolution is a valuable resource for researchers of mouse biology as well as those interested in mouse genetics, evolutionary biology, behaviour, parasitology, and archaeozoology.
Immunogenetics
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Author : Gabriel S Panayi
language : en
Publisher: Butterworth-Heinemann
Release Date : 2014-05-19
Immunogenetics written by Gabriel S Panayi and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-19 with Medical categories.
Immunogenetics is a 12-chapter book that begins with the elucidation of the major histocompatibility complex genes and their role in autoimmune and infectious diseases. Subsequent chapters explore the human major histocompatibility complex, including implications of their complement genes for linkage disequilibrium and disease associations. This book also describes the genetics of human immunoglobulins; T-cell clones; genes of the major histocompatibility complex of the mouse; and the generation, characterization, and use of monoclonal antibodies of murine and human origin. Specific diseases are also discussed; these include spondoarthritides, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and autoimmune thyroid disease. This book will be of beneficial value to specialists in infectious diseases, endocrinology, connective tissue diseases, and neurology, as well as to medical scientists in immunology and molecular biology.
The Mouse In Biomedical Research
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Author : Henry Foster
language : en
Publisher: Elsevier
Release Date : 1981-01-01
The Mouse In Biomedical Research written by Henry Foster and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981-01-01 with Science categories.
The Mouse in Biomedical Research, Volume I: History, Genetics, and Wild Mice focuses on the utility of the mouse as a laboratory animal in biomedical research. A historical perspective on the development and origins of the laboratory and wild mouse is given. The diversity of inbred strains of mice as well as the methods of developing and the genetic monitoring and testing of these strains are discussed. This volume consists of 14 chapters and begins with an overview of mice of the genus Mus and problems concerning evolution within the genus. The following chapters focus on taxonomy, nomenclature, and breeding systems, together with recombinant inbred and congenic resistant mouse strains. Methods of constructing, testing, and monitoring strains are described. Congenic strains, gene mapping, cytogenetics, and murine experimental studies are also considered, along with the histocompatibility-2 complex and radiation genetics. The final chapter is devoted to the pharmacogenetics of the laboratory mouse, paying particular attention to intoxication and detoxication pathways, genetically determined differences in xenobiotic metabolism, and pharmacogenetic polymorphisms. This book will be a useful reference for investigators using mice in many areas of research.
Histocompatibility Antigens
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Author : B. Parham
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Histocompatibility Antigens written by B. Parham and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
The Major Histocompatibility Complex (MHC) was discovered as a con sequence of the chronic problem encountered by cancer biologists in the early years of this century: the failure to maintain tumor lines by serial passage in outbred mice. A number of observations pointed to genetic similarity being a prerequisite for successful transplantation and they were incorporated into a genetic theory of transplantation by C.C. Little. This prompted scientists like Little to initiate breeding experiments designed to test his hypothesis and produce genetically identical mice which would permit the growth of trans planted tumors. Most inbred strains of mice commonly used in immunology derive from those efforts. Transplantation of normal tissues obeyed the same rules found for malignant tissues and rejection was shown to be an immunological phenomenon. G.D. Snell showed that a single genetic locus determined rapid rejection of skin grafts. This was initially called the Major Histocompatibility Locus but was subsequently shown to include many functionally related genes and renamed the Major Histocompatibility Complex (MHC). In mouse this is the H-2 complex and man the HLA complex. During this same period P.A.
The Molecular Biology Of The Major Histocompatibility Complex Of Domestic Animal Species
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Author : Carol M. Warner
language : en
Publisher: Wiley-Blackwell
Release Date : 1988
The Molecular Biology Of The Major Histocompatibility Complex Of Domestic Animal Species written by Carol M. Warner and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Major Histocompatibility Complex categories.