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Biomarker Exploration In Neuropsychiatry Understanding Of The Pathophysiology And Therapeutic Implications


Biomarker Exploration In Neuropsychiatry Understanding Of The Pathophysiology And Therapeutic Implications
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Biomarker Exploration In Neuropsychiatry Understanding Of The Pathophysiology And Therapeutic Implications


Biomarker Exploration In Neuropsychiatry Understanding Of The Pathophysiology And Therapeutic Implications
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Author : HuaLin Cai
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-25

Biomarker Exploration In Neuropsychiatry Understanding Of The Pathophysiology And Therapeutic Implications written by HuaLin Cai and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-25 with Science categories.




Advances In Clinical Chemistry


Advances In Clinical Chemistry
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Author : Gregory S. Makowski
language : en
Publisher: Elsevier
Release Date : 2023-10-17

Advances In Clinical Chemistry written by Gregory S. Makowski and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-17 with Science categories.


Advances in Clinical Chemistry, Volume 116, the latest release in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. - Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science - Authored by world renowned clinical laboratory scientists, physicians and research scientists - Presents the international benchmark for novel analytical approaches in the clinical laboratory



The Heterogeneity Of Neuropsychiatric Disorders


The Heterogeneity Of Neuropsychiatric Disorders
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Author : Lu Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-02-10

The Heterogeneity Of Neuropsychiatric Disorders written by Lu Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-10 with Medical categories.




Neurophysiologic Biomarkers In Neuropsychiatric Disorders


Neurophysiologic Biomarkers In Neuropsychiatric Disorders
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Author : Daniel C. Javitt
language : en
Publisher: Springer Nature
Release Date : 2024-11-19

Neurophysiologic Biomarkers In Neuropsychiatric Disorders written by Daniel C. Javitt and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-19 with Medical categories.


This book reviews neurophysiological biomarkers in neuropsychiatric disorders from the viewpoint of the 21st Century Cures Act, which encourages the use of biomarkers for a variety of purposes during drug development. It covers both traditional etiologic uses of biomarkers and the more recent Biomarkers, EndpointS, and other Tools (BEST) classification scheme used by the FDA, which permits biomarkers for purposes of susceptibility, diagnosis, monitoring, prognosis, pharmacodynamics/response, and safety. The first section of the book describes potential uses of neurophysiologic biomarkers. Subsequent sections focus on a wide range of conditions, including schizophrenia, autism spectrum disorder, Parkinson’s disease, and depression, as well as cross-diagnostic and translational uses, including monkey and rodent analogs. The purpose of the book is to help clinicians understand how neurophysiological biomarkers may be used to understand and manage clinical conditions; to help researchers to understand how biomarkers may be used translationally to test specific theories; and to help pharma investigators to understand how biomarkers can be used to accelerate treatment development.



Emotional Disturbance And Brain Imaging In Neuropsychiatric Disorders


Emotional Disturbance And Brain Imaging In Neuropsychiatric Disorders
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Author : Wenbin Guo
language : en
Publisher: Frontiers Media SA
Release Date : 2021-05-05

Emotional Disturbance And Brain Imaging In Neuropsychiatric Disorders written by Wenbin Guo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-05 with Medical categories.




Improving Diagnosis Treatment And Prognosis Of Neuropsychiatric Disorders By Leveraging Neuroimaging Based Machine Learning


Improving Diagnosis Treatment And Prognosis Of Neuropsychiatric Disorders By Leveraging Neuroimaging Based Machine Learning
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Author : Baojuan Li
language : en
Publisher: Frontiers Media SA
Release Date : 2022-12-29

Improving Diagnosis Treatment And Prognosis Of Neuropsychiatric Disorders By Leveraging Neuroimaging Based Machine Learning written by Baojuan Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-29 with Science categories.




The Handbook Of Neuropsychiatric Biomarkers Endophenotypes And Genes


The Handbook Of Neuropsychiatric Biomarkers Endophenotypes And Genes
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Author : Michael Ritsner
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-04-21

The Handbook Of Neuropsychiatric Biomarkers Endophenotypes And Genes written by Michael Ritsner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-21 with Science categories.


Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer's disease, epilepsy, alcoholism, substance abuse and others are some of the most debilitating illnesses worldwide characterized by the complexity of causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunities to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.



Biomarkers In Neuropsychiatry


Biomarkers In Neuropsychiatry
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Author : Antonio L. Teixeira
language : en
Publisher: Springer Nature
Release Date : 2023-11-30

Biomarkers In Neuropsychiatry written by Antonio L. Teixeira and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-30 with Science categories.


This book presents the ‘state of the art’ of biomarkers research in neuropsychiatric conditions, from dementia to eating disorders, as well as providing methodological, practical and ethical issues related to the development of biomarkers. Biomarkers have revolutionized clinical research and practice in most fields of medicine, but psychiatry has lagged behind. However, in the last decade, there has been a growing expectation that biomarkers will advance and, ultimately, reframe psychiatry research and practice. Biomarkers might inform about diagnosis, therapeutics, prognosis, contributing to a ‘personalized medicine’. Understanding their meaning, possibilities and limitations will help clinicians, researchers and students in the related areas navigate and excel in the challenging and ever changing field of neuropsychiatric disorders.



Glutamate Related Biomarkers For Neuropsychiatric Disorders


Glutamate Related Biomarkers For Neuropsychiatric Disorders
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Author : Hsien-Yuan Lane
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-15

Glutamate Related Biomarkers For Neuropsychiatric Disorders written by Hsien-Yuan Lane and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-15 with categories.




Bipolar Disorder


Bipolar Disorder
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Author : Ives Cavalcante Passos
language : en
Publisher: Springer Nature
Release Date : 2025-05-20

Bipolar Disorder written by Ives Cavalcante Passos and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-20 with Medical categories.


Bipolar disorder is a complex disease and requires specialized care for its assessment and effective treatment. It has a worldwide prevalence of about 2% and is among the top 10 leading causes of disability adjusted life years in young adults. Additionally, people with bipolar disorder die around 10 years earlier, and the lifetime risk of suicide is estimated to be at least 20 times that of the general population. Although these findings illustrate the severity and complexity of this illness, we are living exciting times in the field of bipolar disorder for several reasons. Over the last 20 years, novel and evidence based pharmacological and psychosocial strategies have been added to the treatment of bipolar disorder. Several studies addressed the natural history of the disease and showed that the course of bipolar disorder is heterogeneous but, on average, the risk of recurrence increases with the number of previous episodes. Neuroscience has shed light on the molecular underpinnings of the potential decline in cognition and physical health that takes place in some people with bipolar disorder. Some studies added weight to the theory that immune activation is a key component in driving the changes that take place in the brain and its periphery. Lastly, new technologies and lifestyle approaches are gaining tracking in the field of bipolar disorder. Smartphone apps and sensors have promise to provide the means to digital interventions. Moreover, machine learning algorithms and big data have the potential to pave the way to predictive psychiatry, an exciting new field, where the use of large data sets may allow us to predict responses and clinical outcomes, such as suicide attempts. The book is intended for psychiatrists, psychologists, and other mental health professionals. Written by experts, the 41 chapters are divided in six sections to discuss: The natural history of bipolar disorder; Biological underpinnings; Pharmacological treatment; Psychosocial interventions; Special populations; and New approaches to diagnosis and intervention. It will also discuss the use of antipsychotics and lithium as disease modifying agents, and clinical progression and neuroprogression concepts. Bipolar Disorder - An Evidence-Based Clinical Guide will arm clinicians and researchers with the latest findings, as well as refine the necessary skills to provide the best clinical care.