Biomarker Studies In Brain Aging


Biomarker Studies In Brain Aging
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Biomarker Studies In Brain Aging


Biomarker Studies In Brain Aging
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Author : Maddy Evans
language : en
Publisher: American Medical Publishers
Release Date : 2023-09-19

Biomarker Studies In Brain Aging written by Maddy Evans and has been published by American Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Medical categories.


Biomarkers of aging refer to those biomarkers that can predict functional capacity at a later age more accurately than chronological age. Validated biomarkers of aging can enable interventions which can extend the lifespan, as any changes in the biomarkers can be observed during the life span of the organism. The levels of CD4 and CD8 memory T cells along with naive T cells are found to provide an estimate of lifespan. One of the significant biomarker of aging is the epigenetic clock, which has the capability to forecast human chronological age accurately. Some of the other prominent biomarkers of determining brain aging are proteomic clocks and neuroimaging age predictors. Furthermore, cell counts and blood chemistry can also be used for predicting chronological age accurately. This book is compiled in such a manner, that it will provide in-depth knowledge about the biomarker studies in brain aging. From theories to research to practical applications, case studies related to all contemporary topics of relevance to this area of study have been included herein. This book will provide comprehensive knowledge to the readers.



Biomarkers To Disentangle The Physiological From Pathological Brain Aging


Biomarkers To Disentangle The Physiological From Pathological Brain Aging
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Author : F. G. Guerini
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-22

Biomarkers To Disentangle The Physiological From Pathological Brain Aging written by F. G. Guerini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-22 with categories.




Reviews On Biomarker Studies In Aging And Anti Aging Research


Reviews On Biomarker Studies In Aging And Anti Aging Research
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Author : Paul C. Guest
language : en
Publisher: Springer Nature
Release Date : 2019-09-06

Reviews On Biomarker Studies In Aging And Anti Aging Research written by Paul C. Guest and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-06 with Science categories.


Using both epidemiological and model organism approaches, we have gained new insights into the physiological and molecular aspects of aging, which has led to significant advancements in potential anti-aging strategies. Reviews on Biomarker Studies in Aging and Anti-Aging Research presents a series of reviews in various aspects of aging and age-related disease research along with several methods which have shown progress as potential anti-aging approaches. The book is aimed at researchers in the areas of aging and chronic disease, as well as to clinical scientists, physicians and major drug companies. It provides important information on disease mechanisms, and each chapter is presented in the context of the aging process, specific chronic diseases or different therapeutic areas.



Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimer S Disease


Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimer S Disease
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Author : Ai-Ling Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-10

Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimer S Disease written by Ai-Ling Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-10 with Science categories.




Preclinical Biomarkers And Functional Compensation In Brain Aging


Preclinical Biomarkers And Functional Compensation In Brain Aging
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Author : Panteleimon Giannakopoulos
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-10

Preclinical Biomarkers And Functional Compensation In Brain Aging written by Panteleimon Giannakopoulos and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-10 with categories.




Redox Signaling And Biomarkers In Ageing


Redox Signaling And Biomarkers In Ageing
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Author : Ufuk Çakatay
language : en
Publisher: Springer Nature
Release Date : 2021-12-02

Redox Signaling And Biomarkers In Ageing written by Ufuk Çakatay and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-02 with Medical categories.


This book aims to present the age-related alterations in redox signaling networks and their diagnostic biomarkers in aging cells using multidisciplinary approach. Establishing sensitive and specific biomarkers of dynamic redox homeostasis is crucially important in the development of effective antiaging and senolytic interventions. Recent years have seen tremendous advances in the understanding of redox signaling events which highlight the process of aging and age-related pathologies. A major challenge in biological aging research is developing reliable biomarkers to determine the consequences of disrupted redox signaling networks long before the clinical diagnosis of age-related diseases is made. Therefore, we have chosen to concentrate on aging-induced aberrant redox signaling networks, their biomarkers, and pathological consequences in this book. Although oxidation is a natural metabolic process, the imbalance in the level of oxidants and antioxidants causes oxidative stress and eventually leads to inflammatory conditions, diabetes, neurodegenerative diseases, and cancer. Novel redox-sensitive biomarkers for the evaluation of aging-induced proteinopathies such as amyloid ß and tau proteins in Alzheimer's disease, α-synuclein in Parkinson's disease, and islet amyloid polypeptides in type 2 diabetes mellitus recently drew the attention of researchers. Inside this textbook, readers will find comprehensive perspectives on the association between redox homeostasis and the aging process both at the molecular and clinical levels. Due to the inherent relationship between impaired metabolic activities and oxidative stress, the temporal interaction between intermediary metabolism and disturbed redox status can lead to greater susceptibility to aging-induced diseases and disorders, such as cardiovascular diseases, hypertension, and diabetes. This knowledge could be a key to continued research toward improving medication regimens such as in cancer and cardiovascular therapies, and procedural outcomes for patients. This book brings together current research evidence and knowledge on redox signaling and biomarkers in aging in chapters written by leading global experts in this rapidly evolving field. We hope that this textbook is of interest to a wide group of researchers, advanced students, scientifically curious non-specialist readers and clinicians alike.



Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimer S Disease


Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimer S Disease
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Author : Ai-Ling Lin
language : en
Publisher:
Release Date : 2020

Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimer S Disease written by Ai-Ling Lin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



Biomarkers Of Human Aging


Biomarkers Of Human Aging
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Author : Alexey Moskalev
language : en
Publisher: Springer Nature
Release Date : 2019-09-13

Biomarkers Of Human Aging written by Alexey Moskalev and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-13 with Science categories.


This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging. In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function). The book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging. Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.



Biomarkers Of Brain Injury And Neurological Disorders


Biomarkers Of Brain Injury And Neurological Disorders
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Author : Kevin K. W. Wang
language : en
Publisher: CRC Press
Release Date : 2014-10-28

Biomarkers Of Brain Injury And Neurological Disorders written by Kevin K. W. Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-28 with Medical categories.


This book explores the recent advances in the techniques and platforms used in biomarker research that have revolutionized the way we study, diagnose, and treat brain injury conditions. The contributors describe different biomarker studies pertaining to brain injury and other neurological disorders and analyze the different models and technologies



Exploring Reliable Markers And Prediction Indexes For The Progression From Subjective Cognitive Decline To Cognitive Impairment


Exploring Reliable Markers And Prediction Indexes For The Progression From Subjective Cognitive Decline To Cognitive Impairment
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Author : Ying Han
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-08

Exploring Reliable Markers And Prediction Indexes For The Progression From Subjective Cognitive Decline To Cognitive Impairment written by Ying Han and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-08 with Science categories.