Biomarkers Of The Tumor Microenvironment
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Biomarkers Of The Tumor Microenvironment
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Author : Lars A. Akslen
language : en
Publisher: Springer
Release Date : 2017-08-02
Biomarkers Of The Tumor Microenvironment written by Lars A. Akslen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-02 with Medical categories.
This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Practical applications, in terms of how biomarkers are increasingly included in therapy protocols, will also be discussed. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focusing on cross-talk between different cell types in tumors.
Biomarkers Of The Tumor Microenvironment
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Author : Lars A. Akslen
language : en
Publisher: Springer Nature
Release Date : 2022-07-12
Biomarkers Of The Tumor Microenvironment written by Lars A. Akslen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-12 with Medical categories.
This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed. Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types in tumors. The textbook provides a comprehensive overview of the microenvironment in various contexts from the perspectives of experienced and accomplished cancer researchers and clinicians.
Therapeutic Opportunities And Innovative Biomarkers In Tumor Microenvironment
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Author : Zhenyu Jia
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-19
Therapeutic Opportunities And Innovative Biomarkers In Tumor Microenvironment written by Zhenyu Jia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-19 with Medical categories.
Handbook Of Therapeutic Biomarkers In Cancer
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Author : Sherry X. Yang
language : en
Publisher: CRC Press
Release Date : 2021-02-01
Handbook Of Therapeutic Biomarkers In Cancer written by Sherry X. Yang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-01 with Medical categories.
This book provides a comprehensive overview of the fast-evolving subject of clinical application of cancer therapeutic biomarkers. The second edition captures significant progress of cancer immunotherapy and emphasizes the genetic basis for selective cancer treatment. It covers an in-depth insight on biomarkers across a broad area of cancer research and oncology with a wealth of integrated genetic and molecular information about specific therapies by a multidisciplinary team of internationally recognized experts. Each chapter focuses on a class of targeted, immunologic, or chemotherapy agents and their companion biomarkers that predict response, benefit or resistance, and severe adverse event. The book will serve as a handbook for health professionals and scientists on the current applicable biomarkers in the management of cancer. The vision into the systemic classification and statistical consideration of therapeutic biomarkers summarized by the book editors and chapter authors will help advance precision medicine—a precisely tailored cancer treatment strategy for cancer patient care.
Histopathology
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Author : Supriya Srivastava
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-09-19
Histopathology written by Supriya Srivastava and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-19 with Medical categories.
This book, "Histopathology-An Update" is a comprehensive book that deals with the latest advances in the field of histopathology. This book will be of help to pathologists, clinicians and researchers in the latest update in histopathology of various organs.
The Handbook Of Biomarkers
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Author : Kewal K. Jain
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-02-06
The Handbook Of Biomarkers written by Kewal K. Jain and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-06 with Medical categories.
Of the thousands of biomarkers that are currently being discovered, relatively few are being validated for further applications, and the potential of a biomarker can be quite difficult to evaluate. To aid in this imperative research, Dr. Kewal K. Jain’s Handbook of Biomarkers thoroughly describes many different types of biomarkers and their discovery using various "-omics" technologies, such as proteomics and metabolomics, along with the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials. With biomarkers described first according to technologies and then according to various diseases, this detailed book features the key correlations between diseases and classifications of biomarkers, which provides the reader with a guide to sort out current and future biomarkers. Comprehensive and cutting-edge, The Handbook of Biomarkers serves as a vital guide to furthering ourunderstanding of biomarkers, which, by facilitating the combination of therapeutics with diagnostics, promise to play an important role in the development of personalized medicine, one of the most important emerging trends in healthcare today.
Unveiling Biomarkers And Mechanisms In The Tumor Immune Nexus
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Author : Wantao Wu
language : en
Publisher: Frontiers Media SA
Release Date : 2025-03-20
Unveiling Biomarkers And Mechanisms In The Tumor Immune Nexus written by Wantao Wu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-20 with Medical categories.
The interplay between cancer cells and the immune system is a critical area of research, with recent advancements highlighting the potential of immunotherapy in offering durable responses across various cancer types. Immune checkpoint inhibitors, in particular, have emerged as a cornerstone of cancer therapy, transforming patient outcomes. However, the heterogeneity of tumor-immune interactions poses significant challenges, with a considerable fraction of patients not responding to such treatments. This underscores the urgent need for a deeper understanding of the molecular and cellular underpinnings of these interactions, to harness the full potential of immunotherapy. This Research Topic aims to address the complex landscape of tumor-immune interactions, focusing on identifying and leveraging novel biomarkers and mechanisms that can predict and enhance the efficacy of immunotherapy. Given the pivotal role of the immune system in controlling and eradicating cancer, understanding these interactions at a granular level could lead to more personalized and effective treatment strategies. Recent advances in technologies such as next-generation sequencing, single-cell RNA sequencing, and mass cytometry have opened new avenues for dissecting the complexity of the tumor microenvironment and immune evasion strategies. This collection seeks to compile cutting-edge research that employs these technologies to uncover new biomarkers, understand resistance mechanisms, and identify potential therapeutic targets within the immune contexture of tumors. By bridging gaps in knowledge and fostering innovation, this topic aims to propel the field towards more predictive and responsive immunotherapy approaches.
Biomarker Landscape In Cancer Research
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Author : Ranjita Shegokar
language : en
Publisher: Academic Press
Release Date : 2025-05-23
Biomarker Landscape In Cancer Research written by Ranjita Shegokar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-23 with Science categories.
Biomarker Landscape in Cancer Research examines the impact of early detection, predication of aggressiveness, and the determination of the best treatment for cancers. With a strong focus on the status, challenges, and prospects of biomarker measurements' tools and technology, the book also examines clinical translation-related knowledge and the prognosis of different organ related cancers. In 21 chapters, it describes current and new diagnostic tools in twenty different cancers and explores how innovations in the cancer diagnostic space could make cancer screening and early detection more straightforward.This book is a timely and valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field. - Provides essential information on the most recent developments in the biomarker landscape of different cancer types - Explains current technologies and their applications in the biomarker cancer research landscape - Includes contributions from oncologists, biomedical engineers, pharmaceutical scientists, and manufacturers
Novel Biomarkers For Predicting Response To Cancer Immunotherapy
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Author : Jinghua Pan
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-11
Novel Biomarkers For Predicting Response To Cancer Immunotherapy written by Jinghua Pan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-11 with Medical categories.
Immunotherapy has revolutionized the treatment of malignancies. Targeting of immune checkpoints cytotoxic T-lymphocyte-associated protein 4, programmed cell death protein 1 (PD-1) and its ligand (PD-L1) has led to improving survival in a subset of patients. Despite their remarkable success, clinical benefit remains limited to only a subset of patients. A significant limitation behind these current treatment modalities is an irregularity in clinical response, which is especially pronounced among checkpoint inhibition. Currently, relevant predictors of cancer immunotherapy response include microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR), expression of PD-L1, tumor mutation burden (TMB), immune genomic characteristics, and tumor infiltrating lymphocytes (TILs). However, none of them have sufficient evidence to be a stratification factor. Moreover, as the combined strategies for effective cancer immunotherapy had been developed in multiple tumors, such as Immunotherapy combined with chemotherapy, radiotherapy, targeted therapy and anti-angiogenesis therapy. Therefore, the development of novel biomarkers endowed with high sensitivity, specificity and accuracy able to identify which patients may truly benefit from the treatment with cancer immunotherapy would allow to refine the therapeutic selection and to better tailor the treatment strategy.
Cancer Biomarkers And Targets In Digestive Organs
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Author : Nikki P. Lee
language : en
Publisher: MDPI
Release Date : 2019-09-03
Cancer Biomarkers And Targets In Digestive Organs written by Nikki P. Lee and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-03 with Medical categories.
Identification and development of cancer biomarkers and targets have greatly accelerated progress towards precision medicine in oncology. Studies of tumor biology have not only provided insights into the mechanisms underlying carcinogenesis, but also led to discovery of molecules that have been developed into cancer biomarkers and targets. Multi-platforms for molecular characterization of tumors using next-generation genomic sequencing, immunohistochemistry, in situ hybridization, and blood-based biopsies have greatly expanded the portfolio of potential biomarkers and targets. These cancer biomarkers have been developed for diagnosis, early detection, prognosis, and prediction of treatment response. The molecular targets have been exploited for anti-cancer therapy and delivery of therapeutic agents. This Special Issue of Biomedicines focuses on recent advances in the discovery, characterization, translation, and clinical application of cancer biomarkers and targets in malignant diseases of the digestive system. The goal is to stimulate basic and translational research and clinical collaboration in this exciting field with the hope of developing strategies for prevention and early detection/diagnosis of cancer in digestive organs, and improving therapeutic and psychosocial outcomes in patients with these malignant diseases.