Biomarkers Of The Tumor Microenvironment
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Biomarkers Of The Tumor Microenvironment
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Author : Lars A. Akslen
language : en
Publisher: Springer Nature
Release Date : 2022-07-12
Biomarkers Of The Tumor Microenvironment written by Lars A. Akslen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-12 with Medical categories.
This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed. Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types in tumors. The textbook provides a comprehensive overview of the microenvironment in various contexts from the perspectives of experienced and accomplished cancer researchers and clinicians.
Biomarkers Of The Tumor Microenvironment
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Author : Lars A. Akslen
language : en
Publisher: Springer
Release Date : 2017-08-02
Biomarkers Of The Tumor Microenvironment written by Lars A. Akslen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-02 with Medical categories.
This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Practical applications, in terms of how biomarkers are increasingly included in therapy protocols, will also be discussed. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focusing on cross-talk between different cell types in tumors.
Therapeutic Opportunities And Innovative Biomarkers In Tumor Microenvironment
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Author : Zhenyu Jia
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-19
Therapeutic Opportunities And Innovative Biomarkers In Tumor Microenvironment written by Zhenyu Jia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-19 with Medical categories.
The Role Of The Tumor Microenvironment Tme And Relevant Novel Biomarkers In Oncogenesis
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Author : Zhouxiao Li
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-15
The Role Of The Tumor Microenvironment Tme And Relevant Novel Biomarkers In Oncogenesis written by Zhouxiao Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-15 with Science categories.
Tumor Microenvironment
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Author : Jacinta Serpa
language : en
Publisher: Springer Nature
Release Date : 2020-03-04
Tumor Microenvironment written by Jacinta Serpa and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-04 with Medical categories.
The way a cell undergoes malignant transformation should meet their capacity of surviving in the microenvironment of the organ where the cancer will develop. Metabolic adaptation is for sure one of the criteria that must be accomplished, driven by metabolic plasticity that allows the adaptation of cancer cells to the availability of energy and biomass sources that will sustain cell survival and proliferation. Each human organ has a particular microenvironment which depends on several cell types and in some cases also on symbiotic microorganisms. These biological partners are constantly sharing organic compounds and signaling molecules that will control mitogenesis, cell death and differentiation, accounting for the organ's function. Nevertheless, cancer cells are capable of taking advantage of this metabolic and signaling microenvironmental dynamics. In this book, we intend to present the different components of the microenvironment driving the metabolic fitness of cancer cells. The metabolic changes required for establishing a tumor in a given microenvironment and how these metabolic changes limit the response to drugs will generally be the major items addressed. It is important to mention not only aspects of the microenvironment that stimulate metabolic changes and that select better adapted tumor cells, but also how this regulation of cell plasticity is made. Thus, the signaling pathways that orchestrate and are orchestrated throughout this panoply of metabolic rearrangements will also be addressed in this book. The subjects will be presented from the conceptual point of view of the cross-cancer mechanisms and also particularizing some models that can be examples and enlightening within the different areas.
Tumor Microenvironment
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Author : Peter P. Lee
language : en
Publisher: Springer Nature
Release Date : 2020-03-25
Tumor Microenvironment written by Peter P. Lee and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-25 with Medical categories.
This book addresses the biological processes relevant to the immune phenotypes of cancer and their significance for immune responsiveness, based on the premise that malignant cells manipulate their surroundings through an evolutionary process that is controlled by interactions with innate immune sensors as well as the adaptive recognition of self/non-self. Checkpoint inhibitor therapy is now an accepted new form of cancer treatment. Other immuno-oncology approaches, such as adoptive cell therapy and metabolic inhibitors, have also shown promising results for specific indications. Immune resistance is common, however, limiting the efficacy of immunotherapy in many common cancer types. The reasons for such resistance are diverse and peculiar to the immune landscapes of individual cancers, and to the treatment modality used. Accordingly, approaches to circumvent resistance need to take into account context-specific genetic, biological and environmental factors that may affect the cancer immune cycle, and which can best be understood by studying the target tissue and correlated systemic immune markers. Understanding the major requirements for the evolutionary process governing human cancer growth in the immune-competent host will guide effective therapeutic choices that are tailored to the biology of individual cancers.
Tumor Microenvironment Cellular Metabolic And Immunologic Interactions
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Author : Debabrata Banerjee
language : en
Publisher: Springer Nature
Release Date : 2021-12-09
Tumor Microenvironment Cellular Metabolic And Immunologic Interactions written by Debabrata Banerjee and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-09 with Medical categories.
Over the past decade, the tumor microenvironment has become one of the most important research areas in cancer biology, as cells within the tumor microenvironment, despite being outnumbered by healthy cells, are able to evade surveillance and immune-mediated destruction. While researchers have learned a great deal about the cellular and structural makeup of the tumor microenvironment, there has been a growing understanding of the metabolic interplay between the tumor micronenvironment’s various cellular constituents and how each of them contributes to overall tumor growth and metastases. This new volume will guide researchers, students, oncologists and academics through a rapidly developing and changing field with a thorough understanding of tumor microenvironment biology from a cellular, structural, metabolic, and immunological perspective.
Volume Ii Tumor Microenvironment In Cancer Hallmarks And Therapeutics
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Author : Na Luo
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-26
Volume Ii Tumor Microenvironment In Cancer Hallmarks And Therapeutics written by Na Luo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-26 with Science categories.
Systematic Identification Of Novel Diagnostic And Prognostic Tumor Biomarkers Based On Multi Omics Data Analysis Of Solid Tumors
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Author : Ming Jun Zheng
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-08
Systematic Identification Of Novel Diagnostic And Prognostic Tumor Biomarkers Based On Multi Omics Data Analysis Of Solid Tumors written by Ming Jun Zheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-08 with Science categories.
Cancer Biomarkers
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Author : Gagan Deep
language : en
Publisher: Humana
Release Date : 2022-02-23
Cancer Biomarkers written by Gagan Deep and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-23 with Medical categories.
This detailed volume explores numerous methods used in basic science laboratories to characterize cancer-related biomarkers, vital for better managing cancer burden, including cancer risk assessment, cancer diagnosis, determining cancer progression, and therapeutic response. From a radiography method to an examination of single-cell RNA-seq and computational analysis tools in cancer research, this book delves into many techniques that could provide valuable molecular information about the tumor and its microenvironment components. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cancer Biomarkers: Methods and Protocols offers researchers multiple helpful ways to study cancer-associated molecular biomarkers.