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Biomaterial Based Approaches To Study The Tumour Microenvironment


Biomaterial Based Approaches To Study The Tumour Microenvironment
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Biomaterial Based Approaches To Study The Tumour Microenvironment


Biomaterial Based Approaches To Study The Tumour Microenvironment
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Author : Jessica O Winter
language : en
Publisher: Royal Society of Chemistry
Release Date : 2022-12-07

Biomaterial Based Approaches To Study The Tumour Microenvironment written by Jessica O Winter and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-07 with Technology & Engineering categories.


The tumour microenvironment is increasingly recognized as an important contributor to cancer progression and treatment. However, most cancer studies continue to be performed in 2D tissue culture dishes that do not capture the characteristics of the tumour niche. This book provides an introduction to the rich chemical, topographical, and mechanical cues in the tumour microenvironment and then introduces readers to bioengineering strategies, including scaffold design and synthesis, chemical signalling and delivery, and co-culture, microfluidics, and organ-on-a-chip tools that can be used to mimic tumour microenvironment features. This book also includes discussion of emerging imaging methods compatible with tumour microenvironment mimicking biomaterials and discusses applications of such models in immuno-oncology, metastasis, and drug screening. Edited by two leaders in the field, this book will appeal to graduate students and researchers working in biomaterials science, chemical and biomedical engineering departments.



Biomaterial Based Approaches To Study The Tumour Microenvironment


Biomaterial Based Approaches To Study The Tumour Microenvironment
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Author : Jessica O. Winter
language : en
Publisher:
Release Date : 2022-12-02

Biomaterial Based Approaches To Study The Tumour Microenvironment written by Jessica O. Winter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-02 with categories.


This book provides an introduction to the rich chemical, topographical, and mechanical cues in the tumour microenvironment and then introduces readers to bioengineering strategies.



Lignin Based Materials


Lignin Based Materials
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Author : Kuruvilla Joseph
language : en
Publisher: Royal Society of Chemistry
Release Date : 2023-06-14

Lignin Based Materials written by Kuruvilla Joseph and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-14 with Technology & Engineering categories.


Current environmental and energy concerns have led to lignin gaining increased attention in the last decade as a renewable biomass. Due to its structural and functional properties, such as antimicrobial behaviour, biodegradability, biocompatibility and ease of surface modifications, lignin-based materials have gained popularity in the biomedical field with applications ranging from tissue engineering scaffolds and wound dressing materials to drug delivery carriers. Using this book, the reader will learn about the chemistry of lignin, and the characterization, fabrication and properties of lignin-based composites with different matrices (thermosets, thermoplastics, elastomers etc.). In addition, the book illustrates how these materials are used in medical applications, covering drug delivery, wound dressing, tissue engineering, imaging, etc. Providing a neat overview of the current research for the biomaterials science community, this book is a one-stop resource for researchers and practitioners working on lignin-based biomaterials. For those active in the broader fields of materials science and biomedical engineering, this will be a useful reference and study aid.



Injectable Smart Hydrogels For Biomedical Applications


Injectable Smart Hydrogels For Biomedical Applications
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Author : Jagan Mohan Dodda
language : en
Publisher: Royal Society of Chemistry
Release Date : 2024-07-19

Injectable Smart Hydrogels For Biomedical Applications written by Jagan Mohan Dodda and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-19 with Technology & Engineering categories.


A demonstration of the synthetic strategies available and and an exploration into the range of applications injectable smart hydrogels offer as a minimally-invasive alternative to traditional hydrogels.



Multicomponent Hydrogels


Multicomponent Hydrogels
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Author : Jagan Mohan Dodda
language : en
Publisher: Royal Society of Chemistry
Release Date : 2023-05-22

Multicomponent Hydrogels written by Jagan Mohan Dodda and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-22 with Science categories.


Hydrogels are highly hydrated three dimensional networks with the ability to mimic the extracellular matrix of bodily tissues and have thus found application in a wide range of biomedical applications. Unique physiochemical properties such as biocompatibility, water permeability, stimuli responsiveness and self-healing characteristics make them especially useful for use as scaffolds and matrices drug delivery, tissue engineering/regeneration and sensing. Their weak and brittle nature, however, often limits their widespread application where improved mechanical strength is required. To resolve this problem, there has been a significant amount of research into the improvement of their mechanical properties. Among these efforts, versatile multicomponent hydrogels have received much attention as their physiochemical properties can be structurally engineered to provide a wide range of desired properties. These multicomponent formulations also allow for the combination of natural and synthetic polymers, which offers the scope to exploit the advantages of each component, with the synergistic effects resulting from mutual interactions. This book critically discusses the fundamental chemistry, synthesis, characterisation, physiochemical and biological properties of various types of multicomponent hydrogels. It reviews the different strategies employed in designing and synthesizing cutting-edge multicomponent hydrogels and their key applications in biomedical fields. The work is suitable for researchers working in the specific area of multicomponent hydrogels, and also more generally for those working in materials science, biomedical engineering, biomaterials science and tissue engineering.



Electrospinning


Electrospinning
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Author : Khalid S. Essa
language : en
Publisher: BoD – Books on Demand
Release Date : 2024-04-24

Electrospinning written by Khalid S. Essa and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-24 with Technology & Engineering categories.


Electrospinning - Theory, Applications, and Update Challenges is a comprehensive guide that delves into the principles, techniques, and applications of this cutting-edge technology. Electrospinning, a versatile and innovative process, has revolutionized industries such as health care, textiles, and materials science. The first section presents a detailed overview of electrospinning, covering topics ranging from the fundamentals of electrostatics and polymer science to advanced electrospinning techniques and industrial applications. The second section covers the intricacies of fiber formation, the influence of process parameters, and the wide array of materials that can be spun into fibers. The book provides valuable insights into the latest developments and future prospects of electrospinning.



Handbook Of Biomaterials For Medical Applications Volume 2


Handbook Of Biomaterials For Medical Applications Volume 2
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Author : Deepa Suhag
language : en
Publisher: Springer Nature
Release Date : 2024-08-18

Handbook Of Biomaterials For Medical Applications Volume 2 written by Deepa Suhag and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-18 with Technology & Engineering categories.


“Handbook on Biomaterials for Medical Applications: Applications " is a comprehensive exploration of the cutting-edge developments in the field of biomedical materials, with a strong focus on their multifunctional applications in therapeutics. This book delves into the innovative materials and techniques that are revolutionizing the way we approach healthcare, offering readers valuable insights into the latest breakthroughs and their potential impact on medical treatments. Its text is richly illustrated with diagrams and tables, facilitating both the understanding and application of complex concepts. This book can be a valuable reference for scholars, researchers, and healthcare practitioners.



Biomaterials For 3d Tumor Modeling


Biomaterials For 3d Tumor Modeling
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Author : Subhas C. Kundu
language : en
Publisher: Elsevier
Release Date : 2020-08-22

Biomaterials For 3d Tumor Modeling written by Subhas C. Kundu and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-22 with Technology & Engineering categories.


Biomaterials for 3D Tumor Modeling reviews the fundamentals and most relevant areas of the latest advances of research of 3D cancer models, focusing on biomaterials science, tissue engineering, drug delivery and screening aspects. The book reviews advanced fundamental topics, including the causes of cancer, existing cancer models, angiogenesis and inflammation during cancer progression, and metastasis in 3D biomaterials. Then, the most relevant biomaterials are reviewed, including methods for engineering and fabrication of biomaterials. 3D models for key biological systems and types of cancer are also discussed, including lung, liver, oral, prostate, pancreatic, ovarian, bone and pediatric cancer. This book is suitable for those working in the disciplines of materials science, biochemistry, genetics, molecular biology, drug delivery and regenerative medicine. - Reviews key biomaterials topics, including synthetic biomaterials, hydrogels, e-spun materials and nanoparticles - Provides a comprehensive overview of 3D cancer models for key biological systems and cancer types - Includes an overview of advanced fundamental concepts for an interdisciplinary audience in materials science, biochemistry, regenerative medicine and drug delivery



Revisiting Seed And Soil A New Approach To Target Hibernating Dormant Tumor Cells 2nd Edition


Revisiting Seed And Soil A New Approach To Target Hibernating Dormant Tumor Cells 2nd Edition
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Author : Dalit Barkan
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-07

Revisiting Seed And Soil A New Approach To Target Hibernating Dormant Tumor Cells 2nd Edition written by Dalit Barkan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-07 with Medical categories.


Metastasis is the major cause of mortality in cancer patients. Metastases can be present at the time of diagnosis or can occur years or decades after the removal of the primary tumor and treatment. This long latency in the manifestation of recurrent metastatic disease is explained clinically by the persistence of quiescent tumor cells that disseminated early in the course of the disease from the primary tumor to select distant organs. These residing disseminated tumor cells (DTCs) at distant organs lay dormant and asymptomatic until reawakened to form overt metastases. Importantly, the quiescent nature of these “hibernating” DTCs facilitates their resistance to conventional therapies that target actively dividing tumor cells. Therefore, unraveling the biology of dormancy and reactivation of the residing DTCs to life-threatening lesions is of utmost importance in order to develop new therapeutic strategies to prevent the recurrent metastatic disease from ever emerging or to better treat these recurrent cancers. The mechanisms underlying the biology of tumor dormancy and their reactivation to overt metastases are just beginning to emerge thanks to a growing appreciation of the potentially chronic nature of some cancers and the development of experimental model systems for their study. In this Research Topic, we will follow the journey of circulating tumor cells (CTCs) dispatching from the primary site until their successful lodging into a new and foreign site to become DTCs. We will explore the intrinsic mechanisms along with microenvironmental cues and niches that they encounter during their journey that may dictate their fate.



Breast Cancer Pathophysiology An Interdisciplinary Approach


Breast Cancer Pathophysiology An Interdisciplinary Approach
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Author : Nima Rezaei
language : en
Publisher: Springer Nature
Release Date : 2024-07-22

Breast Cancer Pathophysiology An Interdisciplinary Approach written by Nima Rezaei and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-22 with Medical categories.


Breast cancer is one of the most prevalent malignancies worldwide, particularly in females, with a high rate of cancer-related deaths globally. Increasing age, obesity, harmful use of alcohol, family history of breast cancer, starting age of menstrual periods, and tobacco use are some of the risk factors for breast cancer. The fifth volume of the “Interdisciplinary Cancer Research” series, entitled “Breast Cancer Pathophysiology: An Interdisciplinary Approach” publishes comprehensive volumes on the mechanisms of breast cancer, early detection, assessment, and patient outcome. The role of defective estrogen signals, membrane estrogen receptor, and dietary polyunsaturated fatty acids in breast cancer are also presented in this volume. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value to researchers, oncologists, and oncosurgeons who wish to extend their knowledge on breast cancer.