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Biomechanics And Mechanobiology Of Aneurysms


Biomechanics And Mechanobiology Of Aneurysms
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Biomechanics And Mechanobiology Of Aneurysms


Biomechanics And Mechanobiology Of Aneurysms
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Author : Tim McGloughlin
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-15

Biomechanics And Mechanobiology Of Aneurysms written by Tim McGloughlin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-15 with Technology & Engineering categories.


Cardiovascular disease is the leading cause of morbidity and premature death of modern era medicine. It is estimated that approximately 81 million people in the United States (US) currently have one or more of the many forms of cardiovascular disease, resulting in 1 in every 2.8 deaths, or 900,000 deaths per year. 40% of all deaths in Europe are a result of cardiovascular disease in people under the age of 75. Aneurysms form a significant portion of these cardiovascular related deaths and are defined as a permanent and irreversible localised dilation of a blood vessel greater than 50% of its normal diameter. Although aneurysms can form in any blood vessel, the more lethal aneurysms develop in the cranial arteries, and in the thoracic aorta and abdominal aorta. Frequently aneurysms are undetected and if left untreated may eventually expand until rupture with very high levels of morbidity and mortality. The biomechanics and mechanobiology of aneursymal diseases are not fully understood and this monograph aims to provide new insights into aneurysm aetiology and behavior based on the most recent biomechanics research related to this important topic. The contributors to this volume bring together a unique blend of expertise in experimental, computational and tissue biomechanics relating to aneurysm behavior and enable the reader to gain a fresh understanding of key factors influencing aneurysm behavior and treatment. Biological risk factors such as tobacco smoking, sex, age, hypertension, family history and mechanobiological risk factors such as aneurysm geometry and shape as well as mechanical properties of the diseased tissues are considered in detail as are many of the diagnostic and treatment options.



Cardiovascular Biomechanics


Cardiovascular Biomechanics
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Author : Peter R. Hoskins
language : en
Publisher: Springer
Release Date : 2017-02-16

Cardiovascular Biomechanics written by Peter R. Hoskins and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-16 with Medical categories.


This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.



Encyclopedia Of Biomedical Engineering


Encyclopedia Of Biomedical Engineering
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Author :
language : en
Publisher: Elsevier
Release Date : 2018-09-01

Encyclopedia Of Biomedical Engineering written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-01 with Science categories.


Encyclopedia of Biomedical Engineering, Three Volume Set is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers. Provides students with a concise description of the technologies at the interface of the biological sciences and engineering Covers all aspects of biomedical engineering, also incorporating perspectives from experts working within the domains of biomedicine, medical engineering, biology, chemistry, physics, electrical engineering, and more Contains reputable, multidisciplinary content from domain experts Presents a ‘one-stop’ resource for access to information written by world-leading scholars in the field



Multi Scale Extracellular Matrix Mechanics And Mechanobiology


Multi Scale Extracellular Matrix Mechanics And Mechanobiology
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Author : Yanhang Zhang
language : en
Publisher: Springer
Release Date : 2019-07-12

Multi Scale Extracellular Matrix Mechanics And Mechanobiology written by Yanhang Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-12 with Technology & Engineering categories.


This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.



Biomechanics Of The Aorta


Biomechanics Of The Aorta
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Author : T. Christian Gasser
language : en
Publisher: Elsevier
Release Date : 2024-06-18

Biomechanics Of The Aorta written by T. Christian Gasser and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-18 with Science categories.


Biomechanics of the Aorta: Modelling for Patient Care is a holistic analysis of the aorta towards its biomechanical description. The book addresses topics such as physiology, clinical imaging, tissue and blood flow modeling, along with knowledge that is needed in diagnostics, aortic rupture prediction, assist surgical planning, and more. It encompasses a wide range of topics from the basic sciences (Vascular biology, Continuum mechanics, Image analysis) to clinical applications, as well as describing and presenting computational studies and experimental benches to mimic, understand and propose the best treatment of aortic pathologies. The book begins with an introduction to the fundamental aspects of the anatomy, biology and physiopathology of the aorta and proceeds to present the main computational fluid dynamic studies and biomechanical and mechanobiological models developed over the last decade. With approaches, methodologies and findings from contributors all over the world, this new volume in the Biomechanics of Living Organs series will increase understanding of aortic function as well as improve the design of medical devices and clinical interventions, including surgical procedures. - Comprehensive coverage of the main computational fluid dynamic studies and biomechanical and mechanobiological models developed over the last decade - Introduces the most recent imaging technologies to characterize factors, including aortic geometry, mechanical properties of aortic tissues, and cellular activity in the vessel wall - Synthesizes advances in vascular biomechanics, medical imaging, and computational modeling of finite element fluid and solid models



Orthopaedic Biomechanics


Orthopaedic Biomechanics
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Author : Beth A. Winkelstein
language : en
Publisher: CRC Press
Release Date : 2012-12-18

Orthopaedic Biomechanics written by Beth A. Winkelstein and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-18 with Medical categories.


Given the strong current attention of orthopaedic, biomechanical, and biomedical engineering research on translational capabilities for the diagnosis, prevention, and treatment of clinical disease states, the need for reviews of the state-of-art and current needs in orthopaedics is very timely. Orthopaedic Biomechanics provides an in-depth review of the current knowledge of orthopaedic biomechanics across all tissues in the musculoskeletal system, at all size scales, and with direct relevance to engineering and clinical applications. Discussing the relationship between mechanical loading, function, and biological performance, it first reviews basic structure-function relationships for most major orthopedic tissue types followed by the most-relevant structures of the body. It then addresses multiscale modeling and biologic considerations. It concludes with a look at applications of biomechanics, focusing on recent advances in theory, technology and applied engineering approaches. With contributions from leaders in the field, the book presents state-of-the-art findings, techniques, and perspectives. Much of orthopaedic, biomechanical, and biomedical engineering research is directed at the translational capabilities for the "real world". Addressing this from the perspective of diagnostics, prevention, and treatment in orthopaedic biomechanics, the book supplies novel perspectives for the interdisciplinary approaches required to translate orthopaedic biomechanics to today’s real world.



Multiphysics And Multiscale Modeling


Multiphysics And Multiscale Modeling
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Author : Young W. Kwon
language : en
Publisher: CRC Press
Release Date : 2015-10-05

Multiphysics And Multiscale Modeling written by Young W. Kwon and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-05 with Science categories.


Written to appeal to a wide field of engineers and scientists who work on multiscale and multiphysics analysis, Multiphysics and Multiscale Modeling: Techniques and Applications is dedicated to the many computational techniques and methods used to develop man-made systems as well as understand living systems that exist in nature. Presenting a body



Heart Development And Disease


Heart Development And Disease
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-04-02

Heart Development And Disease written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-02 with Science categories.


Heart Development and Disease, Volume 156 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters including Macrophages during heart valve development, Computational models of cardiovascular biology, Mechanisms of early sarcomere assembly, Role of RNA binding proteins during heart development and disease, Early heart development and morphogenesis, PSC models for development and disease, ECM or SHF development, Role of metabolism during heart development, Cellular ploidy in cardiac biology, and Genetics of CHD in the human population. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Updated release includes the latest information on Heart Development Disease



Biomechanical Modelling At The Molecular Cellular And Tissue Levels


Biomechanical Modelling At The Molecular Cellular And Tissue Levels
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Author : Gerhard A. Holzapfel
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-05

Biomechanical Modelling At The Molecular Cellular And Tissue Levels written by Gerhard A. Holzapfel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-05 with Technology & Engineering categories.




Transport In Biological Media


Transport In Biological Media
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Author : Sid M. Becker
language : en
Publisher: Newnes
Release Date : 2013-05-21

Transport In Biological Media written by Sid M. Becker and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-21 with Technology & Engineering categories.


Transport in Biological Media is a solid resource of mathematical models for researchers across a broad range of scientific and engineering problems such as the effects of drug delivery, chemotherapy, or insulin intake to interpret transport experiments in areas of cutting edge biological research. A wide range of emerging theoretical and experimental mathematical methodologies are offered by biological topic to appeal to individual researchers to assist them in solving problems in their specific area of research. Researchers in biology, biophysics, biomathematics, chemistry, engineers and clinical fields specific to transport modeling will find this resource indispensible. - Provides detailed mathematical model development to interpret experiments and provides current modeling practices - Provides a wide range of biological and clinical applications - Includes physiological descriptions of models