Biopharmaceutics And Relevant Pharmacokinetics
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Biopharmaceutics And Relevant Pharmacokinetics
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Author : John G. Wagner
language : en
Publisher: American Pharmaceutical Association
Release Date : 1971
Biopharmaceutics And Relevant Pharmacokinetics written by John G. Wagner and has been published by American Pharmaceutical Association this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Medical categories.
Essentials Of Biopharmaceutics And Pharmacokinetics E Book
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Author : Ashutosh Kar
language : en
Publisher: Elsevier Health Sciences
Release Date : 2010-09-15
Essentials Of Biopharmaceutics And Pharmacokinetics E Book written by Ashutosh Kar and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-15 with Medical categories.
Essentials of Biopharmaceutics and Pharmacokinetics Kar’s Essentials of Biopharmaceutics and Pharmacokinetics deals with how a drug exerts its action in the human body through the fundamentals of absorption, distribution, metabolism and excretion. The book adopts a growth-oriented format and design that is developed systematically and methodically. The book interrelates five different sections: Section 1 Biopharmaceutics and Pharmacokinetics: What Do They Mean? Section 2 Biopharmaceutics Section 3 Pharmacokinetics Section 4 Clinical Pharmacokinetics Section 5 Bioavailability and Bioequivalence Each section starts with a basic theory and fields of application, focuses on model-independent pharmacokinetic analyses, expatiates various biopharmaceutical aspects of dosage form and evaluation, provides an altogether new approach in understanding both dosage regimen design and individualization, and explains modification in drug molecules related to the pharmacokinetics. Undoubtedly, the unique blend of fundamental principles and latest breakthroughs in the field will certainly provide sufficient subject matter to the students of pharmacy, pharmacology, medicinal chemistry scientists, who need a simple as well as detailed introduction in theory and application.
Biopharmaceutics
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Author : Hannah Batchelor
language : en
Publisher: John Wiley & Sons
Release Date : 2021-12-20
Biopharmaceutics written by Hannah Batchelor and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-20 with Medical categories.
Explore the latest research in biopharmaceutics from leading contributors in the field In Biopharmaceutics - From Fundamentals to Industrial Practice, distinguished Scientists from the UK's Academy of Pharmaceutical Sciences Biopharmaceutica Focus Group deliver a comprehensive examination of the tools used within the field of biopharmaceutics and their applications to drug development. This edited volume is an indispensable tool for anyone seeking to better understand the field of biopharmaceutics as it rapidly develops and evolves. Beginning with an expansive introduction to the basics of biopharmaceutics and the context that underpins the field, the included resources go on to discuss how biopharmaceutics are integrated into product development within the pharmaceutical industry. Explorations of how the regulatory aspects of biopharmaceutics function, as well as the impact of physiology and anatomy on the rate and extent of drug absorption, follow. Readers will find insightful discussions of physiologically based modeling as a valuable asset in the biopharmaceutics toolkit and how to apply the principles of the field to special populations. The book goes on to discuss: Thorough introductions to biopharmaceutics, basic pharmacokinetics, and biopharmaceutics measures Comprehensive explorations of solubility, permeability, and dissolution Practical discussions of the use of biopharmaceutics to inform candidate drug selection and optimization, as well as biopharmaceutics tools for rational formulation design In-depth examinations of biopharmaceutics classification systems and regulatory biopharmaceutics, as well as regulatory biopharmaceutics and the impact of anatomy and physiology Perfect for professionals working in the pharmaceutical and biopharmaceutical industries, Biopharmaceutics - From Fundamentals to Industrial Practice is an incisive and up-to-date resource on the practical, pharmaceutical applications of the field.
Modeling In Biopharmaceutics Pharmacokinetics And Pharmacodynamics
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Author : Panos Macheras
language : en
Publisher: Springer
Release Date : 2016-03-30
Modeling In Biopharmaceutics Pharmacokinetics And Pharmacodynamics written by Panos Macheras and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-30 with Mathematics categories.
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with epirical, compartmental, and stochastic pharmacokinetic models, with two new chapters, one on fractional pharmacokinetics and one on bioequivalence; and the fourth mainly with classical and nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. This second edition has new information on reaction limited models of dissolution, non binary biopharmaceutic classification system, time varying models, and interface models. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. This book will appeal to graduate students and researchers in pharmacology, pharmaceutical sciences, bioengineering, and physiology. Reviews of the first edition: "This book presents a novel modelling approach to biopharmaceutics, pharmacokinetics and pharmacodynamic phenomena. This state-of-the-art volume will be helpful to students and researchers in pharmacology, bioengineering, and physiology. This book is a must for pharmaceutical researchers to keep up with recent developments in this field." (P. R. Parthasarathy, Zentralblatt MATH, Vol. 1103 (5), 2007) "These authors are the unique (or sole) contributors in this area that are working on these questions and bring a special expertise to the field that is now being recognized as essential to understanding biological system and kinetic/dynamic characteristics in drug development...This text is an essential primer for those who would envision the incorporation of heterogeneous approaches to systems where homogeneous approaches are not sufficient to describe the system." (Robert R. Bies, Journal of Clinical Pharmacology, Vol. 46, 2006)
Adme Processes In Pharmaceutical Sciences
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Author : Alan Talevi
language : en
Publisher: Springer
Release Date : 2018-11-30
Adme Processes In Pharmaceutical Sciences written by Alan Talevi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-30 with Medical categories.
Absorption, Distribution, Metabolism and Excretion (ADME) processes and their relationship with the design of dosage forms and the success of pharmacotherapy form the basis of this upper level undergraduate/graduate textbook. As an introduction oriented to pharmacy students, it is also written for scientist from different fields outside of pharmaceutics. (e.g. material scientist, material engineers, medicinal chemists) who might be working in a positions in pharmaceutical companies or whose work might benefit from basic training in the ADME concepts and some biological background. Pedagogical features such as objectives, keywords, discussion questions, summaries and case studies add valuable teaching tools. This book will provide not only general knowledge on ADME processes but also an updated insight on some hot topics such as drug transporters, multi-drug resistance related to pharmacokinetic phenomena, last generation pharmaceutical carriers (nanopharmaceuticals), in vitro and in vivo bioequivalence studies, biopharmaceuticals, pharmacogenomics, drug-drug and food-drug interactions, and in silico and in vitro prediction of ADME properties. In comparison with other similar textbooks, around half of the volume would be focused on the relationship between expanding scientific fields and ADME processes. Each of these burgeoning fields has a separate chapter in the second part of the volume, and was written with leading experts on the correspondent topic, including scientists and academics from USA and UK (Duquesne University School of Pharmacy, Indiana University School of Medicine, University of Utah College of Pharmacy, University of Maryland, University of Bath). Additionally, each of the initial chapters dealing with the generalities of drug absorption, distribution, metabolism and excretion would include relevant, classic examples related to each topic with appropriate illustrations (e.g. importance of active absorption of levodopa, implications in levodopa administration, drug drug interactions and food drug interactions emerging from the active uptake; intoxication with paracetamol as a result of glutathione depletion, CYP induction and its relationship with acute liver failure caused by paracetamol, etc). ADME Processes and Pharmaceutical Sciences is written as a core textbook for ADME processes, pharmacy, pharmacokinetics, drug delivery, biopharmaceutics, drug disposition, drug design and medicinal chemistry courses.
Biopharmaceutics And Clinical Pharmacokinetics
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Author : Notari
language : en
Publisher: CRC Press
Release Date : 1986-08-26
Biopharmaceutics And Clinical Pharmacokinetics written by Notari and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-08-26 with Science categories.
Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- Preface to the Fourth Edition -- Preface to the Third Edition -- Preface to the Second Edition -- Preface to the First Edition -- Nomenclature -- 1: Introduction -- References -- 2: Rates, Rate Constants, and Order -- I. Order -- II. Rates and Rate Constants -- 3: Active and Passive Transport -- I. Introduction -- II. Passive Transport -- III. Active Transport -- References -- 4: Pharmacokinetics -- I. Introduction -- II. Drug Disposition -- III. Constant-Rate Intravenous Infusion -- IV. Compartmental Models and Their Limitations -- V. Absorption Rate Constants -- References -- 5: Biopharmaccutics -- I. Extravascular Administration -- II. Absorption of Drugs from the Gastrointestinal Tract -- III. Factors Influencing Bioavailability -- IV. Evaluation of the Bioavailability of a Single Drug -- V. Drug Delivery to Prolong Duration -- References -- 6: Dosage Regimens -- I. Introduction -- II. Accumulation During Repetitive Dosing -- III. Adjustment of Dosage Regimen in Renal Failure -- IV. Multiple Dosing of Constant-Rate Intravenous Infusions -- References -- 7: Pharmacokinetic Aspects of Structural Modifications in Drug Design and Therapy -- I. Introduction -- II. Antimicrobial Agents -- III. Pharmacokinetics of Prodrugs -- IV. Stereoisomers -- References -- 8: Pharmacokinetic Applications in Clinical Practice -- I. Introduction -- II. Pharmacokinetic Drug Interactions -- III. Clinical Pharmacokinetics -- References -- Appendix -- Index
Biopharmaceutics Pharmacokinetics
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Author : Dr. A. R. Paradkar
language : en
Publisher: Pragati Books Pvt. Ltd.
Release Date : 2008-10-06
Biopharmaceutics Pharmacokinetics written by Dr. A. R. Paradkar and has been published by Pragati Books Pvt. Ltd. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-06 with categories.
Biopharmaceutics And Clinical Pharmacokinetics
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Author : Robert E. Notari
language : en
Publisher:
Release Date : 1980
Biopharmaceutics And Clinical Pharmacokinetics written by Robert E. Notari and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Medical categories.
1 Bioavailability 1; 2. Rate processes in biological systems 5; 3. Principles of pharmacokinetics 45; 4. Biopharmaceutics: clinical applications of pharmacokinetic parameters 107; 5. Dosage regimens 173; 6. Pharmacokinetic aspects of structural modification in drug design and therapy 213; 7. An overview of pharmacokinetic applications in clinical practice 290; Appendix A: Fick's law 338; Appendix B: Vd 341; Appendix C: Area under I.V. curves 346; Appendix D: Multiple-dose equations 348; Appendix E: List of symbols of general occurrence 351.
Basic Pharmacokinetics
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Author : Sunil S. Jambhekar
language : en
Publisher:
Release Date : 2009
Basic Pharmacokinetics written by Sunil S. Jambhekar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.
This is an essential guide to the study of absorption, distribution, metabolism and elimination of drugs in the body. It provides the reader with a basic understanding of the principles of pharmacokinetics and biopharmaceutics and how these principles, along with the equations presented in each chapter, can be applied to achieve successful drug therapy.
Biopharmaceutics And Clinical Pharmacokinetics
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Author : Milo Gibaldi
language : en
Publisher:
Release Date : 1977
Biopharmaceutics And Clinical Pharmacokinetics written by Milo Gibaldi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Medical categories.