Biostatistical Genetics And Genetic Epidemiology
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Biostatistical Genetics And Genetic Epidemiology
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Author : Robert C. Elston
language : en
Publisher: John Wiley & Sons
Release Date : 2002-04-22
Biostatistical Genetics And Genetic Epidemiology written by Robert C. Elston and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-04-22 with Medical categories.
Human Genetics concerns the study of genetic forces in man. By studying our genetic make-up we are able to understand more about our heritage and evolution. Some of the original, and most significant research in genetics centred around the study of the genetics of complex diseases - genetic epidemiology. This is the third in a highly successful series of books based on articles from the Encyclopedia of Biostatistics. This volume will be a timely and comprehensive reference, for a subject that has seen a recent explosion of interest following the completion of the first draft of the Human Genome Mapping Project. The editors have updated the articles from the Human Genetics section of the EoB, have adpated other articles to give them a genetic feel, and have included a number of newly commissioned articles to ensure the work is comprehensive and provides a self-contained reference.
Biostatistical Genetics And Genetic Epidemiology
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Author : Robert C. Elston
language : en
Publisher: John Wiley & Sons
Release Date : 2002-04-22
Biostatistical Genetics And Genetic Epidemiology written by Robert C. Elston and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-04-22 with Medical categories.
Human Genetics concerns the study of genetic forces in man. By studying our genetic make-up we are able to understand more about our heritage and evolution. Some of the original, and most significant research in genetics centred around the study of the genetics of complex diseases - genetic epidemiology. This is the third in a highly successful series of books based on articles from the Encyclopedia of Biostatistics. This volume will be a timely and comprehensive reference, for a subject that has seen a recent explosion of interest following the completion of the first draft of the Human Genome Mapping Project. The editors have updated the articles from the Human Genetics section of the EoB, have adpated other articles to give them a genetic feel, and have included a number of newly commissioned articles to ensure the work is comprehensive and provides a self-contained reference.
Biostatistical Genetics And Genetic Epidemiology
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Author : Azhar Ul Haque Sario
language : en
Publisher: Azhar UL Haque Sario
Release Date : 2024-03-11
Biostatistical Genetics And Genetic Epidemiology written by Azhar Ul Haque Sario and has been published by Azhar UL Haque Sario this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-11 with Health & Fitness categories.
Biostatistical Genetics and Genetic Epidemiology: A Comprehensive Guide to Unlocking the Secrets of Genes and Disease In the intricate world where biology, statistics, and medicine converge lies a field of extraordinary promise: biostatistical genetics and genetic epidemiology. This powerful combination holds the key to deciphering the complex interplay between our genes and the diseases that afflict us. If understanding the origins of illness, revolutionizing drug development, and tailoring treatments precisely to individuals are aspirations that intrigue you, then this book is an essential companion on your journey. This comprehensive text delves into the foundations of genetics and epidemiology, equipping you with the indispensable tools of the trade. You'll master the fundamental statistical methodologies specifically designed to unlock the hidden patterns within genetic data. The book unveils the power of linkage analysis, tracing the inheritance of genes within families to pinpoint disease-related regions. It then leads you on a thrilling exploration of genome-wide association studies (GWAS) - the robust techniques used to meticulously scan the entire human genome, pinpointing subtle genetic variations that influence our susceptibility to disease. The journey doesn't stop there. You'll grapple with the intricacies of analyzing complex diseases like cancer, heart conditions, and neurological disorders, where the interplay of genes and environment weave a tangled web. This book offers insights into how genetic epidemiology is changing how we track, prevent, and manage infectious diseases - a challenge of paramount importance in our interconnected world. In the era of personalized medicine, 'pharmacogenomics' stands tall. This field investigates how our genetic makeup influences our response to medications. Discover how your genes might play a role in the effectiveness and potential side effects of the treatments you receive. This knowledge paves the way for groundbreaking therapies tailored to your unique genetic profile. Biostatistical Genetics and Genetic Epidemiology also casts a critical eye on the far-reaching ethical, legal, and social implications raised by genetic research. As we uncover the secrets of our DNA, questions of privacy, discrimination, and equitable access to genetic technologies take center stage. This guide ventures beyond the traditional boundaries of genetics and disease. It examines how statistical methods illuminate the dynamic world of gene expression, the process by which our genes are switched on and off. It explores 'statistical epigenetics', investigating how modifiable chemical marks on DNA interact with our environment to impact our health. Embark on an intellectual odyssey into population genetics, the study of how gene frequencies evolve within populations. You'll see how this field sheds light on human history, ancestry, and the forces that shape our genetic diversity. Discover how statistical methods intertwine with systems biology, helping us model intricate biological networks and gain an integrated understanding of health and disease. This book provides a solid foundation in the statistical techniques used in clinical genetics, where accurate diagnosis, risk assessment, and informed family planning are of the essence. It sheds light on statistical methods powering cancer genomics, an area of research rapidly transforming diagnosis and treatment of this complex group of diseases. Additionally, you'll encounter the burgeoning field of microbiome research. Learn how statistical tools help us analyze the vast microbial communities residing within us, revealing their surprising impact on our health and well-being.
Statistical Methods In Genetic Epidemiology
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Author : Duncan C. Thomas
language : en
Publisher: Oxford University Press
Release Date : 2004-01-29
Statistical Methods In Genetic Epidemiology written by Duncan C. Thomas and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-29 with Medical categories.
This balanced and well-integrated text gives a lucid overview of the entire process of genetic epidemiology, from familial aggregation through segregation, likage, and association studies. It is illustrated throughout with examples from the literature on cancer genetics. Statistical concepts are developed in depth, but with a focus on applications. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics are included. Oriented to graduate students in biostatistics, epidemiology, and human genetics, the book will also be a useful reference for researchers. It gives equal emphasis to study designs and data analysis.
Biostatistical Methods In Genetics And Genetic Epidemiology An Introduction To Genetic Epidemiology Biostatistical Genetics
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Author : Lynn Decollblanc
language : en
Publisher: Lynn Decollblanc
Release Date : 2023-06-19
Biostatistical Methods In Genetics And Genetic Epidemiology An Introduction To Genetic Epidemiology Biostatistical Genetics written by Lynn Decollblanc and has been published by Lynn Decollblanc this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-19 with Medical categories.
Biostatistical Methods in Genetics and Genetic Epidemiology offers a comprehensive exploration of the powerful intersection between biostatistics, genetics, and epidemiology. This authoritative book delves into the fundamental principles and advanced methodologies that drive genetic research and enable a deeper understanding of the complex relationship between genes, diseases, and population health. With a focus on practical applications and real-world examples, this book equips readers with the necessary tools to navigate the vast landscape of genomic analysis. From unraveling genetic variation to investigating disease risk factors and exploring the role of environmental factors, this book provides a solid foundation for researchers, practitioners, and students in the fields of biostatistics, genetics, epidemiology, and related disciplines. Key Features: Comprehensive Coverage: Explore the essential concepts, techniques, and study designs used in genetic research, including case-control studies, linkage analysis, genome-wide association studies, and more. Statistical Methods: Gain a deep understanding of the statistical principles and methodologies employed in genetic analysis, including statistical genetics, genetic risk prediction, and analysis of complex traits. Genetic Epidemiology: Examine the integration of genetics and epidemiology, uncovering how genetic factors interact with environmental and lifestyle factors to influence disease outcomes and population health. Practical Examples: Benefit from real-world examples and case studies that demonstrate the application of biostatistical methods in unraveling the genetic underpinnings of diseases, identifying genetic risk factors, and informing public health interventions. Ethical and Legal Considerations: Explore the ethical implications and challenges surrounding genetic research, genetic counseling, privacy, and data sharing. Emerging Trends: Stay up-to-date with the latest advancements in the field, including precision medicine, pharmacogenomics, epigenetics, and the integration of multi-omics data. Biostatistical Methods in Genetics and Genetic Epidemiology is an invaluable resource for researchers, practitioners, and students seeking to unravel the complexities of genetics and its impact on human health. Whether you are a biostatistician, geneticist, epidemiologist, or medical professional, this book will empower you to navigate the rapidly evolving field of genomics and make meaningful contributions to precision medicine, disease prevention, and public health initiatives.
A Statistical Approach To Genetic Epidemiology
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Author : Andreas Ziegler
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-24
A Statistical Approach To Genetic Epidemiology written by Andreas Ziegler and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-24 with Science categories.
A Statistical Approach to Genetic Epidemiology After studying statistics and mathematics at the University of Munich and obtaining his doctoral degree from the University of Dortmund, Andreas Ziegler received the Johann-Peter-Süssmilch-Medal of the German Association for Medical Informatics, Biometry and Epidemiology for his post-doctoral work on “Model Free Linkage Analysis of Quantitative Traits” in 1999. In 2004, he was one of the recipients of the Fritz-Linder-Forum-Award from the German Association for Surgery.
An Introduction To Genetic Epidemiology
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Author : Palmer, Lyle J.
language : en
Publisher: Policy Press
Release Date : 2011-05-31
An Introduction To Genetic Epidemiology written by Palmer, Lyle J. and has been published by Policy Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-31 with Medical categories.
This book brings together leading experts to provide an introduction to genetic epidemiology that begins with a primer in human molecular genetics through all the standard methods in population genetics and genetic epidemiology required for an adequate grounding in the field.
Biostatistics For Human Genetic Epidemiology
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Author : Bertram K. C. Chan
language : en
Publisher: Springer
Release Date : 2018-10-24
Biostatistics For Human Genetic Epidemiology written by Bertram K. C. Chan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-24 with Medical categories.
The book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solve problems in quantitative Genetic Epidemiology Biostatistics for Human Genetic Epidemiology provides statistical methodologies and R recipes for human genetic epidemiologic problems. It begins by introducing all the necessary probabilistic and statistical foundations, before moving on to topics related human genetic epidemiology, with R codes illustrations for various examples. This clear and concise book covers human genetic epidemiology, using R in data analysis, including multivariate data analysis. It examines probabilistic and statistical theories for modeling human genetic epidemiology – leading the readers through an effective epidemiologic model, from simple to advanced levels. Classical mathematical, probabilistic, and statistical theory are thoroughly discussed and presented. This book also presents R as a calculator and using R in data analysis. Additionally, it covers Advanced Human Genetic Data Concepts, the Study of Human Genetic Variation, Manhattan Plots, as well as the Procedures for Multiple Comparison. Numerous Worked Examples are provided for illustrations of concepts and real-life applications. Biostatistics for Human Genetic Epidemiology is an ideal reference for professionals and students in Medicine (particularly in Preventive Medicine and Public Health Medical Practices), as well as in Genetics, Epidemiology, and Biostatistics.
Biostatistics And Epidemiology
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Author : Sylvia Wassertheil-Smoller
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Biostatistics And Epidemiology written by Sylvia Wassertheil-Smoller and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Biostatistics and Epidemiology/A Primer for Health Professionals offers practical guidelines and gives a concise framework for research and interpretation in the field. In addition to major sections covering statistics and epidemiology, the book includes a comprehensive exploration of scientific methodology, probability, and the clinical trial. The principles and methods described in this book are basic and apply to all medical subspecialties, psychology and education. The primer will be especially useful to public health officials and students looking for an understandable treatment of the subject.
Biostatistical Methods
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Author : Stephen W. Looney
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03
Biostatistical Methods written by Stephen W. Looney and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Science categories.
Leading biostatisticians and biomedical researchers describe many of the key techniques used to solve commonly occurring data analytic problems in molecular biology, and demonstrate how these methods can be used in the development of new markers for exposure to a risk factor or for disease outcomes. Major areas of application include microarray analysis, proteomic studies, image quantitation, genetic susceptibility and association, evaluation of new biomarkers, and power analysis and sample size.