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Statistical Methods In Genetic Epidemiology

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Statistical Methods In Genetic Epidemiology

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Author : Duncan C. Thomas
language : en
Publisher: Oxford University Press
Release Date : 2004-01-29

Statistical Methods In Genetic Epidemiology written by Duncan C. Thomas and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-29 with Medical categories.

This balanced and well-integrated text gives a lucid overview of the entire process of genetic epidemiology, from familial aggregation through segregation, likage, and association studies. It is illustrated throughout with examples from the literature on cancer genetics. Statistical concepts are developed in depth, but with a focus on applications. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics are included. Oriented to graduate students in biostatistics, epidemiology, and human genetics, the book will also be a useful reference for researchers. It gives equal emphasis to study designs and data analysis.

Statistical Methods In Genetic Epidemiology

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Author : Duncan C. Thomas
language : en
Publisher: Oxford University Press
Release Date : 2004-01-29

This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. It follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population. Examples from the literature on the genetic epidemiology of breast and colorectal cancer, among other diseases, illustrate this process. Although the book is oriented primarily towards graduate students in epidemiology, biostatistics and human genetics, it will also serve as a comprehensive reference work for researchers. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics will help make the book accessible to those coming from one of these fields without a background in the others. It strikes a good balance between epidemiologic study designs and statistical methods of data analysis.

Statistical Methods In Genetic Epidemiology I

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Author :
language : en
Publisher:
Release Date : 2000

Statistical Methods In Genetic Epidemiology I written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.

Biostatistical Methods In Genetics And Genetic Epidemiology An Introduction To Genetic Epidemiology Biostatistical Genetics

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Author : Lynn Decollblanc
language : en
Publisher: Lynn Decollblanc
Release Date : 2023-06-19

Biostatistical Methods In Genetics And Genetic Epidemiology An Introduction To Genetic Epidemiology Biostatistical Genetics written by Lynn Decollblanc and has been published by Lynn Decollblanc this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-19 with Medical categories.

Biostatistical Methods in Genetics and Genetic Epidemiology offers a comprehensive exploration of the powerful intersection between biostatistics, genetics, and epidemiology. This authoritative book delves into the fundamental principles and advanced methodologies that drive genetic research and enable a deeper understanding of the complex relationship between genes, diseases, and population health. With a focus on practical applications and real-world examples, this book equips readers with the necessary tools to navigate the vast landscape of genomic analysis. From unraveling genetic variation to investigating disease risk factors and exploring the role of environmental factors, this book provides a solid foundation for researchers, practitioners, and students in the fields of biostatistics, genetics, epidemiology, and related disciplines. Key Features: Comprehensive Coverage: Explore the essential concepts, techniques, and study designs used in genetic research, including case-control studies, linkage analysis, genome-wide association studies, and more. Statistical Methods: Gain a deep understanding of the statistical principles and methodologies employed in genetic analysis, including statistical genetics, genetic risk prediction, and analysis of complex traits. Genetic Epidemiology: Examine the integration of genetics and epidemiology, uncovering how genetic factors interact with environmental and lifestyle factors to influence disease outcomes and population health. Practical Examples: Benefit from real-world examples and case studies that demonstrate the application of biostatistical methods in unraveling the genetic underpinnings of diseases, identifying genetic risk factors, and informing public health interventions. Ethical and Legal Considerations: Explore the ethical implications and challenges surrounding genetic research, genetic counseling, privacy, and data sharing. Emerging Trends: Stay up-to-date with the latest advancements in the field, including precision medicine, pharmacogenomics, epigenetics, and the integration of multi-omics data. Biostatistical Methods in Genetics and Genetic Epidemiology is an invaluable resource for researchers, practitioners, and students seeking to unravel the complexities of genetics and its impact on human health. Whether you are a biostatistician, geneticist, epidemiologist, or medical professional, this book will empower you to navigate the rapidly evolving field of genomics and make meaningful contributions to precision medicine, disease prevention, and public health initiatives.

A Statistical Approach To Genetic Epidemiology

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Author : Andreas Ziegler
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-24

A Statistical Approach To Genetic Epidemiology written by Andreas Ziegler and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-24 with Science categories.

A Statistical Approach to Genetic Epidemiology After studying statistics and mathematics at the University of Munich and obtaining his doctoral degree from the University of Dortmund, Andreas Ziegler received the Johann-Peter-Süssmilch-Medal of the German Association for Medical Informatics, Biometry and Epidemiology for his post-doctoral work on “Model Free Linkage Analysis of Quantitative Traits” in 1999. In 2004, he was one of the recipients of the Fritz-Linder-Forum-Award from the German Association for Surgery.

Biostatistical Genetics And Genetic Epidemiology

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Author : Robert C. Elston
language : en
Publisher: John Wiley & Sons
Release Date : 2002-04-22

Biostatistical Genetics And Genetic Epidemiology written by Robert C. Elston and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-04-22 with Medical categories.

Human Genetics concerns the study of genetic forces in man. By studying our genetic make-up we are able to understand more about our heritage and evolution. Some of the original, and most significant research in genetics centred around the study of the genetics of complex diseases - genetic epidemiology. This is the third in a highly successful series of books based on articles from the Encyclopedia of Biostatistics. This volume will be a timely and comprehensive reference, for a subject that has seen a recent explosion of interest following the completion of the first draft of the Human Genome Mapping Project. The editors have updated the articles from the Human Genetics section of the EoB, have adpated other articles to give them a genetic feel, and have included a number of newly commissioned articles to ensure the work is comprehensive and provides a self-contained reference.

Mathematical And Statistical Methods For Genetic Analysis

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Author : Kenneth Lange
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Mathematical And Statistical Methods For Genetic Analysis written by Kenneth Lange and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Mathematics categories.

During the past decade, geneticists have constructed detailed maps of the human genome and cloned scores of Mendelian disease genes. They now stand on the threshold of sequencing the genome in its entirety. The unprecedented insights into human disease and evolution offered by mapping and sequencing will transform medicine and agriculture. This revolution depends vitally on the contributions of applied mathematicians, statisticians, and computer scientists. Mathematical and Statistical Methods for Genetic Analysis is written to equip graduate students in the mathematical sciences to understand and model the epidemiological and experimental data encountered in genetics research. Mathematical, statistical, and computational principles relevant to this task are developed hand in hand with applications to gene mapping, risk prediction, and the testing of epidemiological hypotheses. The book includes many topics currently accessible only in journal articles, including pedigree analysis algorithms, Markov chain Monte Carlo methods, reconstruction of evolutionary trees, radiation hybrid mapping, and models of recombination. Exercise sets are included. Kenneth Lange is Professor of Biostatistics and Mathematics and the Pharmacia & Upjohn Foundations Research Professor at the University of Michigan. He has held visiting appointments at MIT and Harvard. His research interests include human genetics, population modeling, biomedical imaging, computational statistics, and applied stochastic processes.

A Statistical Approach To Genetic Epidemiology

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Author : Andreas Ziegler
language : en
Publisher: John Wiley & Sons
Release Date : 2010-06-14

An Introduction To Genetic Epidemiology

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Author : Palmer, Lyle J.
language : en
Publisher: Policy Press
Release Date : 2011-05-31

An Introduction To Genetic Epidemiology written by Palmer, Lyle J. and has been published by Policy Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-31 with Medical categories.

This book brings together leading experts to provide an introduction to genetic epidemiology that begins with a primer in human molecular genetics through all the standard methods in population genetics and genetic epidemiology required for an adequate grounding in the field.

Fundamentals Of Genetic Epidemiology

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Author : Muin J. Khoury
language : en
Publisher: Monographs in Epidemiology and
Release Date : 1993

Fundamentals Of Genetic Epidemiology written by Muin J. Khoury and has been published by Monographs in Epidemiology and this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Mathematics categories.

This text integrates the principles, methods and approaches of epidemiology and genetics in the study of disease aetiology. The authors define the central theme of genetic epidemiology as the study of the role of genetic factors and their interaction with environmental factors in the occurrence of disease in populations.

Statistical Methods In Genetic Epidemiology

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