Biotechnology And Production Of Anti Cancer Compounds
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Biotechnology And Production Of Anti Cancer Compounds
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Author : Sonia Malik
language : en
Publisher: Springer
Release Date : 2017-04-21
Biotechnology And Production Of Anti Cancer Compounds written by Sonia Malik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-21 with Science categories.
This book discusses cancers and the resurgence of public interest in plant-based and herbal drugs. It also describes ways of obtaining anti-cancer drugs from plants and improving their production using biotechnological techniques. It presents methods such as cell culture, shoot and root culture, hairy root culture, purification of plant raw materials, genetic engineering, optimization of culture conditions as well as metabolic engineering with examples of successes like taxol, shikonin, ingenol mebutate and podophylotoxin. In addition, it describes the applications and limitations of large-scale production of anti-cancer compounds using biotechnological means. Lastly, it discusses future economical and eco-friendly strategies for obtaining anti-cancer compounds using biotechnology.
Paclitaxel
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Author : Mallappa Kumara Swamy
language : en
Publisher: Academic Press
Release Date : 2021-10-08
Paclitaxel written by Mallappa Kumara Swamy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-08 with Science categories.
Paclitaxel: Sources, Chemistry, Anticancer Actions, and Current Biotechnology provides a comprehensive survey of Paclitaxel and its derivatives chemistry, biosynthesis and anticancer activities. In addition, biotechnological methods, including cell cultures, the use of bioreactors and metabolic engineering strategies to improve Paclitaxel production are also discussed. The book discusses topics such as mechanisms of action against cancer, novel forms of Paclitaxel for an effective cancer treatment, strategies for enhancing its bioavailability, and the application of nanocarriers for its delivery and chemotherapy of cancer. This is a valuable resource for cancer researchers, biotechnologists and members of biomedical field who are interested in the promising anticancer qualities of this antineoplastic drug and how to enhance them for better treatments. Presents detailed information about Paclitaxel research, from its discovery to clinical uses and biotechnological routes of commercial production Focuses on Paclitaxel development as an effective chemotherapeutic drug, along with its application in different types of cancers Encompasses descriptive illustrations and workflows to help the reader fully understand the content and easily apply it to their research
Camptothecin And Camptothecin Producing Plants
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Author : T. Pullaiah
language : en
Publisher: Academic Press
Release Date : 2020-06-18
Camptothecin And Camptothecin Producing Plants written by T. Pullaiah and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-18 with Science categories.
Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemical diversity of camptothecin, extraction and exploitation methods, biosynthesis, biotechnological production and enhancement for drug delivery, and the pharmacological properties of the drugs. The book focuses on camptothecin anticancer properties based on recent developments of biotechnology. Topics emphasize anticancer activities, biosynthesis, potent derivatives currently undergoing experimental phases, and biotechnological methods to enhance the production. This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and members of the biomedical field who are interested in camptothecin and its applicability in cancer treatment. Provides information on camptothecin producing plants and their anticancer properties for the development of new treatments Discusses new applications of camptothecin based on recent biotechnology advancements Presents comprehensive information on the pharmacology of camptothecin for leveraging new anticancer drugs developments
Handbook Of Anticancer Drugs From Marine Origin
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Author : Se-Kwon Kim
language : en
Publisher: Springer
Release Date : 2014-11-27
Handbook Of Anticancer Drugs From Marine Origin written by Se-Kwon Kim and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-27 with Science categories.
This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.
Biotechnology Of Bioactive Compounds
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Author : Vijai Kumar Gupta
language : en
Publisher: John Wiley & Sons
Release Date : 2015-04-20
Biotechnology Of Bioactive Compounds written by Vijai Kumar Gupta and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-20 with Technology & Engineering categories.
Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.
Anticancer Plants Natural Products And Biotechnological Implements
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Author : Mohd Sayeed Akhtar
language : en
Publisher: Springer
Release Date : 2018-07-02
Anticancer Plants Natural Products And Biotechnological Implements written by Mohd Sayeed Akhtar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-02 with Science categories.
This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.
Phytopharmaceuticals And Biotechnology Of Herbal Plants
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Author : Sachidanand Singh
language : en
Publisher: CRC Press
Release Date : 2022-12-28
Phytopharmaceuticals And Biotechnology Of Herbal Plants written by Sachidanand Singh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-28 with Health & Fitness categories.
Plant-based drugs play an important role in all cultures and have been crucial in maintaining health and fighting diseases, and by using contemporary methods of biotechnology, plants with explicit chemical compositions are propagated and genetically upgraded for the mining of pharmaceuticals. Phytopharmaceuticals and Biotechnology of Herbal Plants presents the latest advances in the development of transgenic plants, covering phototherapeutics, secondary metabolite production, metabolomics, metabolic engineering, bioinformatics, quality control of herbal plant products, crop improvement using various breeding techniques, tissue culture techniques, and the future of phytopharmaceuticals. Features: Describes developments and applications of phytopharmaceuticals of herbal plants. Highlights the importance of phytopharmaceutical of plants and potential applications in the food and pharma industries. Provides an overview of research on key anticancer drugs to elucidate the biotechnological approaches for their production in cell cultures. Places special emphasis on the biosynthetic pathway mapping and metabolic engineering. Phytopharmaceuticals and Biotechnology of Herbal Plants will be an invaluable resource to academics and researchers associated with plant science, herbal drug manufacturers, and phytochemists.
Anticancer Plants Mechanisms And Molecular Interactions
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Author : Mohd Sayeed Akhtar
language : en
Publisher: Springer
Release Date : 2018-07-03
Anticancer Plants Mechanisms And Molecular Interactions written by Mohd Sayeed Akhtar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-03 with Science categories.
This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. The book provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.
Anticancer Plants Properties And Application
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Author : Mohd Sayeed Akhtar
language : en
Publisher: Springer
Release Date : 2018-06-29
Anticancer Plants Properties And Application written by Mohd Sayeed Akhtar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-29 with Science categories.
Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types. The anticancer plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities. Anticancer plants: Volume 1, Properties and Application is a very timely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners.
The Complete Book On Biotechnology Based Bulk Drugs
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Author : NPCS Board of Consultants & Engineers
language : en
Publisher: NIIR PROJECT CONSULTANCY SERVICES
Release Date : 2007-01-01
The Complete Book On Biotechnology Based Bulk Drugs written by NPCS Board of Consultants & Engineers and has been published by NIIR PROJECT CONSULTANCY SERVICES this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-01 with Science categories.
Biotechnology has played an essential role in the development of the healthcare chemical industries. The range of product includes diagnostic, prophylactic and therapeutic agents. The discovery of a potentially active compound starts a sequence of exhaustive chemical and biological testing that may culminate in manufacture of the agent or an improved analog. The role of biotechnology in this complex path to regulatory approval and marketing is diverse. Biotechnology is a field of applied biology that involves the use of living organisms and bioprocesses in engineering, technology, medicine and other fields requiring bio products. Biotechnology also utilizes these products for manufacturing purpose. Some of the examples of drugs produced through biotechnology are penicillin, lincomycin, streptomucin, tylosin, peptide antibiotics, cephalosporins, etc. Modern use of similar terms includes genetic engineering as well as cell and tissue culture technologies. Biotechnology draws on the pure biological sciences and in many instances is also dependent on knowledge and methods from outside the sphere of biology. Conversely, modern biological sciences are intimately entwined and dependent on the methods developed through biotechnology and what is commonly thought of as the life sciences industry. The development of biotechnology is taking place in almost all fields of human life. The recent advances in the field of basic genetics have opened up new vistas, potentials and possibilities. Some of the fundamentals of the book are the pharmaceutical industries, marketing strategy, common features in the evolution of products and processes, process technology fermentation, product recovery, new trends in biotechnology, penicillins, biosynthesis and regulation of thienamycin, olivanic acids and epithienamycins, aminoglycoside antibiotics, streptidine and deoxystreptamine, streptomycin, neomycin, paromomycin, ribostamycin and,butirosin gentamicin, micronomicin and sisomicin, tylosin, peptide antibiotics, current applications of peptides, blasticidin S: an agricultural antibiotic bleomycin and bestatin: peptides used in anticancer therapy etc. The present book contains process of biotechnology based bulk drugs like penicillin, B lactam antibiotics, aminoglycoside antibiotics, peptide antibiotics, anti cancer agents, lincomycin etc. This is very resourceful book for entrepreneurs, technocrats, research scholars, libraries etc. TAGS Process for Production of Penicillin, Biotechnology in Bulk Drug Production, Manufacturing of Bulk Drugs, Bulk Drugs Production, Manufacturing Process of Penicillins, Fermentation Process, Novel Fermentation Process, Manufacture Aminoglycoside, Manufacturing Process of Tylosin, Production of Peptides, Production of Streptomycin, Fermentation Process of Cephalosporins, Cephamycin Production, Production of Lincomycin, Drug Development Process, Fermentation Process for Production of Anthracylines, Batch Fermentation Process, Fermentation Process for Production of Nucleosides, Batch Production Process, Interferon Production, Leukocyte Process, Lymphoblastoid Process, Immune Interferon Process, Production of Siderophores, Production of Cloning and Expression, Production of Penicillin, Process of Fermentation, Production of Fermentation, Novel Fermentation Processes for Manufacturing, Novel Fermentation Production, Manufacture of Aminoglycoside, Production of Tylosin, Manufacturing of Peptides, Production of Peptides, Process for Production of Streptomycin, Production of Cephalosporin, Fermentation for Cephalosporin Production, Production of Cephamycin, Lincomycin Production, Anthracycline Production, Process for Production of Anthracycline, Producing Nucleotide by Fermentation, Production of Nucleotides, Batch Production, Production of Interferon, Cloning And Expression of Antibiotic Production, How to Start Anthracycline Processing Industry, Production Of Cephamycin Industry, Most Profitable Novel Fermentation Production Ideas, Cloning and Expression Processing Projects, Small Scale Nucleosides Production Projects, Starting Penicillin Production Business, How to Start Anthracylines Production Business, Bulk Drugs Based Small Scale Industries Projects, NPCS, Niir, Process Technology Books, Business Consultancy, Business Consultant, Project Identification and Selection, Preparation of Project Profiles, Startup, Business Guidance, Business Guidance to Clients, Startup Project for Aminoglycoside Manufacture, Startup Project, Startup Ideas, Project for Startups, Startup Project Plan, Business Start-Up, Business Plan for Startup Business, Great Opportunity for Startup, Small Start-Up Business Project, Start-Up Business Plan for Peptides Production, Start Up India, Stand Up India, Modern Small and Cottage Scale Industries, Profitable Small and Cottage Scale Industries, Setting Up and Opening Your Bulk Drugs Business, How To Start Production of Nucleosides ?, Best Small and Cottage Scale Industries, Bulk Based Business, Profitable Small Scale Manufacturing,