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Biothermodynamics Part C


Biothermodynamics Part C
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Biothermodynamics Part C


Biothermodynamics Part C
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Author :
language : en
Publisher: Academic Press
Release Date : 2010-12-28

Biothermodynamics Part C written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-28 with Science categories.


In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. Biothermodynamics, Part C presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. The use of thermodynamics in biological research is used as an "energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well. - Elucidates the relationships between structure and energetics and their applications to molecular design, aiding researchers in the design of medically important molecules - Provides a "must-have" methods volume that keeps MIE buyers and online subscribers up-to-date with the latest research - Offers step-by-step lab instructions, including necessary equipment, from a global research community



Natural Product Biosynthesis By Microorganisms And Plants Part B


Natural Product Biosynthesis By Microorganisms And Plants Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2012-10-01

Natural Product Biosynthesis By Microorganisms And Plants Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-01 with Science categories.


This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The second of 3 volumes covering Natural product biosynthesis by microorganisms and plants. - This new volume continues the legacy of this premier serial - Contains quality chapters authored by leaders in the field - The second of 3 volumes it has chapters on such topics as biological chlorination, bromination and iodination, and phylogenetic approaches to natural product structure prediction



Synthetic Biology Part A


Synthetic Biology Part A
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Author : Chris Voigt
language : en
Publisher: Academic Press
Release Date : 2011-07-08

Synthetic Biology Part A written by Chris Voigt and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-08 with Science categories.


Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation. - Encompasses a variety of different approaches, methodologies and disciplines - Split into 2 parts and covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation



Synthetic Biology Part B


Synthetic Biology Part B
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Author : Chris Voigt
language : en
Publisher: Academic Press
Release Date : 2011-07-15

Synthetic Biology Part B written by Chris Voigt and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-15 with Science categories.


Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation. - Encompasses a variety of different approaches, methodologies and disciplines - Split into 2 parts and covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation



Protein Engineering For Therapeutics


Protein Engineering For Therapeutics
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Author : K. Dane Wittrup
language : en
Publisher: Academic Press
Release Date : 2012

Protein Engineering For Therapeutics written by K. Dane Wittrup and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Electronic books categories.


This volume of Methods in Enzymology looks at Protein Engineering for Therapeutics. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as Peptides, and Scaffolds Chapters provide an invaluable resource for academics, researchers and students alike. Iinternational board of authors. This volume is split into sections that cover subjects such as Peptides, and Scaffolds



Fragment Based Drug Design


Fragment Based Drug Design
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Author :
language : en
Publisher: Academic Press
Release Date : 2011-02-28

Fragment Based Drug Design written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-28 with Medical categories.


There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits. - Offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens - The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD



Methods In Methane Metabolism Part B


Methods In Methane Metabolism Part B
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Author : Amy Rosenzweig
language : en
Publisher: Academic Press
Release Date : 2011-03-17

Methods In Methane Metabolism Part B written by Amy Rosenzweig and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-17 with Science categories.


Produced by microbes on a large scale, methane is an important alternative fuel as well as a potent greenhouse gas. This volume focuses on microbial methane metabolism, which is central to the global carbon cycle. Both methanotrophy and methanogenesis are covered in detail. Topics include isolation and classification of microorganisms, metagenomics approaches, biochemistry of key metabolic enzymes, gene regulation and genetic systems, and field measurements. The state of the art techniques described here will both guide researchers in specific pursuits and educate the wider scientific community about this exciting and rapidly developing field. - Topics include isolation and classification of microorganisms, metagenomics approaches, biochemistry of key metabolic enzymes, gene regulation and genetic systems and field measurements - The state-of-the-art techniques described here will both guide researchers in specific pursuits and educate the wider scientific community about this exciting and rapidly developing field



Ghrelin


Ghrelin
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Author :
language : en
Publisher: Academic Press
Release Date : 2012-12-17

Ghrelin written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-17 with Science categories.


This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The volume covers ghrelin, and has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice. - Contains quality chapters authored by leaders in the field - Has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice



Research Methods In Biomineralization Science


Research Methods In Biomineralization Science
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Author :
language : en
Publisher: Elsevier
Release Date : 2013-10-31

Research Methods In Biomineralization Science written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-31 with Science categories.


This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in biomineralization science, and includes sections on such topics as determining solution chemistry, structure and nucleation; probing structure and dynamics at surfaces; and interfaces mapping biomineral and morphology and ultrastructure. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in biomineralization science - Contains sections on such topics as and includes sections on such topics as determining solution chemistry, structure and nucleation; probing structure and dynamics at surfaces; and interfaces mapping biomineral and morphology and ultrastructure



Laboratory Methods In Enzymology Cell Lipid And Carbohydrate


Laboratory Methods In Enzymology Cell Lipid And Carbohydrate
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Author :
language : en
Publisher: Academic Press
Release Date : 2013-10-30

Laboratory Methods In Enzymology Cell Lipid And Carbohydrate written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-30 with Science categories.


Methods in Enzymology volumes provide an indispensable tool for the researcher. Each volume is carefully written and edited by experts to contain state-of-the-art reviews and step-by-step protocols. In this volume, we have brought together a number of core protocols concentrating on Cell, Lipid and Carbohydrate, complementing the traditional content that is found in past, present and future Methods in Enzymology volumes. - Indispensable tool for the researcher - Carefully written and edited by experts to contain step-by-step protocols - In this volume we have brought together a number of core protocols concentrating on Cell, Lipid and Carbohydrate