Bisphosphonates In Bone Disease

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Bisphosphonates In Bone Disease

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Author : Herbert Fleisch
language : en
Publisher: Elsevier
Release Date : 2000-06-12

Bisphosphonates In Bone Disease written by Herbert Fleisch and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-06-12 with Medical categories.

This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, Fourth Edition, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revised Fourth Edition contains approximately 50% new material, including information on all of the latest drugs. - The revised fourth edition contains approximately 50% new material - Includes information on all the latest drugs

Bisphosphonates In Bone Disease

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Author : Herbert Fleisch
language : en
Publisher: Elsevier
Release Date : 2000-04-18

Bisphosphonates In Bone Disease written by Herbert Fleisch and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-04-18 with Medical categories.

This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, 4E, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revised Fourth Edition contains approximately 50% new material, including information on all of the latest drugs. * The revised fourth edition contains approximately 50% new material * Includes information on all the latest drugs

Marcus And Feldman S Osteoporosis

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Author : David W. Dempster
language : en
Publisher: Academic Press
Release Date : 2020-10-08

Marcus And Feldman S Osteoporosis written by David W. Dempster and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-08 with Science categories.

Marcus and Feldman's Osteoporosis, Fifth Edition, is the most comprehensive, authoritative reference on this disease. Led by a new editorial team, this fifth edition offers critical information on reproductive and hormonal risk factors, new therapeutics, ethnicity, nutrition, therapeutics, management and economics, comprising a tremendous wealth of knowledge in a single source not found elsewhere. Written by renowned experts in the field, this two-volume reference is a must-have for biomedical researchers, research clinicians, fellows, academic and medical libraries, and any company involved in osteoporosis drug research and development. - Summarizes the latest research in bone biology and translational applications in a range of new therapeutic agents, including essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, parathyroid hormone, and new therapeutic agents - Recognizes the critical importance of new signaling pathways for bone health, including Wnt, OPG and RANK, of interest to both researchers who study bone biology and clinicians who treat osteoporosis - Offers new insights into osteoporosis associated with menopause, pre-menopause, chronic kidney disease, diabetes, HIV and other immune disorders

Osteoporosis In Men

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Author : Eric S. Orwoll
language : en
Publisher: Academic Press
Release Date : 1999-07-15

Osteoporosis In Men written by Eric S. Orwoll and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-07-15 with Medical categories.

Osteoporosis in men is an important clinical problem that has received little attention, both in the medical arena and from the general public. Although the condition affects a higher percentage of women, it is estimated that two million men in the U.S. have osteoporosis, and three million more are at risk. The lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated.Osteoporosis in Men is the first book to explore this issue in depth. This groundbreaking text brings together eminent investigators and clinicians who interpret developments in this emerging field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy. It is an essential reference for researchers, students, and clinicians in bone-related disciplines.Key Features* Provides the first complete description of osteoporosis in men--epidemiology, clinical character, basic aspects, and research directions* Discusses appropriate diagnostic, prevention, and treatment options* Covers a wide range of topics, including the economic impact of fractures on health care expenses* Includes a description of the roles of androgen and estrogen in men* Discusses bone mass measurements and their clinical utility* Explores the essential role of gender in the manifestations of osteoporosis. How is this disorder different in men, and how can we learn from these differences?

Fragility Fracture Nursing

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Author : Karen Hertz
language : en
Publisher: Springer
Release Date : 2018-06-15

Fragility Fracture Nursing written by Karen Hertz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-15 with Medical categories.

This open access book aims to provide a comprehensive but practical overview of the knowledge required for the assessment and management of the older adult with or at risk of fragility fracture. It considers this from the perspectives of all of the settings in which this group of patients receive nursing care. Globally, a fragility fracture is estimated to occur every 3 seconds. This amounts to 25 000 fractures per day or 9 million per year. The financial costs are reported to be: 32 billion EUR per year in Europe and 20 billon USD in the United States. As the population of China ages, the cost of hip fracture care there is likely to reach 1.25 billion USD by 2020 and 265 billion by 2050 (International Osteoporosis Foundation 2016). Consequently, the need for nursing for patients with fragility fracture across the world is immense. Fragility fracture is one of the foremost challenges for health care providers, and the impact of each one of those expected 9 million hip fractures is significant pain, disability, reduced quality of life, loss of independence and decreased life expectancy. There is a need for coordinated, multi-disciplinary models of care for secondary fracture prevention based on the increasing evidence that such models make a difference. There is also a need to promote and facilitate high quality, evidence-based effective care to those who suffer a fragility fracture with a focus on the best outcomes for recovery, rehabilitation and secondary prevention of further fracture. The care community has to understand better the experience of fragility fracture from the perspective of the patient so that direct improvements in care can be based on the perspectives of the users. This book supports these needs by providing a comprehensive approach to nursing practice in fragility fracture care.

Clinical Gynecology

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Author : Eric J. Bieber
language : en
Publisher: Cambridge University Press
Release Date : 2015-04-23

Clinical Gynecology written by Eric J. Bieber and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-23 with Medical categories.

Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

Oral Intravenous Bisphosphonate Induced Osteonecrosis Of The Jaws

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Author : Robert E. Marx
language : en
Publisher:
Release Date : 2006

Oral Intravenous Bisphosphonate Induced Osteonecrosis Of The Jaws written by Robert E. Marx and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.

Oral and Intravenous Bisphosphonate-Induced Osteonecrosis of the Jaws deals with dentistry.

Bisphosphonates And Osteonecrosis Of The Jaw A Multidisciplinary Approach

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Author : Francesco Saverio De Ponte
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-25

Bisphosphonates And Osteonecrosis Of The Jaw A Multidisciplinary Approach written by Francesco Saverio De Ponte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-25 with Medical categories.

During the early 19th century, it was discovered that adding yellow (now called white) phosphorous to matchstick heads made it easier to ignite matches. The phosphorous vapors were breathed in by workers and combined with other chemicals in the body to produce a potent nitrogen-containing bisphosphonate. Today's oral nitrogen-containing bisphosphonates and intravenous nitrogen-containing bisphosphonates circulate around the body the same way as the phosphorous vapors, and are absorbed into bone and ingested by osteoclasts. When this unique binding process of bisphosphonates to bone occurs, osteoclasts are poisoned, and this reduces or eliminates bone turnover. Alveolar bone in the mandible and maxilla turns over more rapidly than in long bones, so the jaws are a better target for bisphosphonate toxicity. It wasn't until 2003 that today's intravenous and oral nitrogen-containing bisphosphonate medications were implicated as major risk factors in the development of exposed necrotic bone of the jaws. Most of the researchers who reported cases of bisphosphonate-induced osteonecrosis of the jaw found that these patients were treated with zoledronate, pamidronate, or a combination of these drugs, which are commonly used for treating breast cancer or myeloma. In about 5% of cases, subjects with BIONJ were being treated for osteoporosis. Precipitating events that contribute to BIONJ are tooth extractions (about 50% of cases), mandibular exostoses, periodontal disease, and local trauma from ill-fitting dentures. It is not known if the placement of dental implants is a precipitating factor. The book aims to meet the need of medical practitioners working in all fields that use bisphosphonates, and to present the conservative and surgical treatment methods currently in use. There will also be detailed information on the literature relating to dental implants in patients treated with bisphosphonates.

Bisphosphonates In Medical Practice

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Author : Reiner Bartl
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-14

Bisphosphonates In Medical Practice written by Reiner Bartl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-14 with Medical categories.

Bones are everybody’s business. This means that clinical osteology, now an independent specialty, nevertheless encompasses all branches of medicine and affects each and every one of us. Intended for doctors who seek precise information on bisphosphonates in medical practice, this book has been designed as an up-to-date manual to deal with the currently recognized indications for bisphosphonates, to outline situations and conditions for prevention of skeletal disorders, and to provide practical guidelines for treatment.