Bisphosphonates In Bone Disease


Bisphosphonates In Bone Disease
DOWNLOAD

Download Bisphosphonates In Bone Disease PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Bisphosphonates In Bone Disease book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page





Bisphosphonates In Bone Disease


Bisphosphonates In Bone Disease
DOWNLOAD

Author : Herbert Fleisch
language : en
Publisher: Elsevier
Release Date : 2000-04-18

Bisphosphonates In Bone Disease written by Herbert Fleisch and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-04-18 with Medical categories.


This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, 4E, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revised Fourth Edition contains approximately 50% new material, including information on all of the latest drugs. * The revised fourth edition contains approximately 50% new material * Includes information on all the latest drugs



Bisphosphonates In Medical Practice


Bisphosphonates In Medical Practice
DOWNLOAD

Author : Reiner Bartl
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-14

Bisphosphonates In Medical Practice written by Reiner Bartl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-14 with Medical categories.


Bones are everybody’s business. This means that clinical osteology, now an independent specialty, nevertheless encompasses all branches of medicine and affects each and every one of us. Intended for doctors who seek precise information on bisphosphonates in medical practice, this book has been designed as an up-to-date manual to deal with the currently recognized indications for bisphosphonates, to outline situations and conditions for prevention of skeletal disorders, and to provide practical guidelines for treatment.



Bisphosphonates And Osteonecrosis Of The Jaw A Multidisciplinary Approach


Bisphosphonates And Osteonecrosis Of The Jaw A Multidisciplinary Approach
DOWNLOAD

Author : Francesco Saverio De Ponte
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-25

Bisphosphonates And Osteonecrosis Of The Jaw A Multidisciplinary Approach written by Francesco Saverio De Ponte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-25 with Medical categories.


During the early 19th century, it was discovered that adding yellow (now called white) phosphorous to matchstick heads made it easier to ignite matches. The phosphorous vapors were breathed in by workers and combined with other chemicals in the body to produce a potent nitrogen-containing bisphosphonate. Today's oral nitrogen-containing bisphosphonates and intravenous nitrogen-containing bisphosphonates circulate around the body the same way as the phosphorous vapors, and are absorbed into bone and ingested by osteoclasts. When this unique binding process of bisphosphonates to bone occurs, osteoclasts are poisoned, and this reduces or eliminates bone turnover. Alveolar bone in the mandible and maxilla turns over more rapidly than in long bones, so the jaws are a better target for bisphosphonate toxicity. It wasn't until 2003 that today's intravenous and oral nitrogen-containing bisphosphonate medications were implicated as major risk factors in the development of exposed necrotic bone of the jaws. Most of the researchers who reported cases of bisphosphonate-induced osteonecrosis of the jaw found that these patients were treated with zoledronate, pamidronate, or a combination of these drugs, which are commonly used for treating breast cancer or myeloma. In about 5% of cases, subjects with BIONJ were being treated for osteoporosis. Precipitating events that contribute to BIONJ are tooth extractions (about 50% of cases), mandibular exostoses, periodontal disease, and local trauma from ill-fitting dentures. It is not known if the placement of dental implants is a precipitating factor. The book aims to meet the need of medical practitioners working in all fields that use bisphosphonates, and to present the conservative and surgical treatment methods currently in use. There will also be detailed information on the literature relating to dental implants in patients treated with bisphosphonates.



Bisphosphonates And Metastatic Bone Disease


Bisphosphonates And Metastatic Bone Disease
DOWNLOAD

Author : R. D. Rubens
language : en
Publisher: Parthenon Publishing
Release Date : 1994

Bisphosphonates And Metastatic Bone Disease written by R. D. Rubens and has been published by Parthenon Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Bone metastasis categories.




Bisphosphonate On Bones


Bisphosphonate On Bones
DOWNLOAD

Author : Olav Leonardus Maria Bijvoet
language : en
Publisher: Elsevier Science Health Science Division
Release Date : 1995

Bisphosphonate On Bones written by Olav Leonardus Maria Bijvoet and has been published by Elsevier Science Health Science Division this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medical categories.


During the last quarter of a century, bisphosphonates have become a major tool in the management of bone disease, second only to vitamin D. A great deal of research on these agents has been carried out by investigators from a variety of disciplines, but until now the resulting information had not been presented in a systematic fashion, addressing the needs of clinicians, basic researchers, and their colleagues in the pharmaceutical industry. Written in its entirety by scientists who have been active and reputed in their different areas from the beginning of bisphosphonate research, this volume will enable physicians to profit optimally from the accumulated experience, to guide pharmacists in their teaching, to help pharmacologist in designing new bisphosphonates and to stimulate biologists in better elucidating their mechanisms of action.



Bisphosphonates And Tumor Osteolysis


Bisphosphonates And Tumor Osteolysis
DOWNLOAD

Author : Kurt W. Brunner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Bisphosphonates And Tumor Osteolysis written by Kurt W. Brunner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


This volume informs the reader about basic chemical and experimental aspects of the bisphosphonates, their application in neoplastic hypercalcemia, and the basic effects of these drugs in neoplastic osteolysis. Initial reports, which need confirmation by larger randomized studies, also deal with the long-term application and possibly favorable influence of bisphosphonates in metastatic bone disease. It is vital for medical oncologists and interested internists to keep abreast of recent information in this new area of clinical cancer research.



Bisphosphonates Advances In Research And Application 2012 Edition


Bisphosphonates Advances In Research And Application 2012 Edition
DOWNLOAD

Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26

Bisphosphonates Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.


Bisphosphonates—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Bisphosphonates in a concise format. The editors have built Bisphosphonates—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bisphosphonates in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Bisphosphonates—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Pocket Guide To Bisphosphonates In Clinical Practice


Pocket Guide To Bisphosphonates In Clinical Practice
DOWNLOAD

Author : R. Bartl
language : en
Publisher: Wiley-Blackwell
Release Date : 2002-02-08

Pocket Guide To Bisphosphonates In Clinical Practice written by R. Bartl and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-02-08 with Medical categories.


The potential capacity of the biphosphonates to intervene in osseous remodeling was recognized more than 30 years ago. The biphosphonates inhibit osteoclastic activity. In spite of advances in early detection, surgey, chemo-and radiotherapy, metastatic bone disease is still a major and in many cases intractable clinical problem. The biphosphonates are now the most effective agents in the management of bone metastases - as shown by trials in patients with breast and prostate cancer, and in multiple myeloma. Bone pain, new ostelytic events and pathologic fractures are decreased and complications associated with these events are avoided. Existing osteolytic lesions may even be reversed. New fields of indications of biphosphonates are shown to be in the adjuvant therapy of breast cancer and in stage 1 multiple myeloma to prevent skeletal destruction and also to inhibit tumor growth. Over the past few years the biphosphonates have proved their value also in many other conditions such as Paget's disease of bone, osseous disorders with an osteoclastic component leading to osteopenia/osteoporosis, in congenial, endocrine and metabolic disorders. Perhaps, for the future and for the next millennium the most widespread and extensive use to these anti-osteoclastic component leading to osteopenia/osteoporosis, in congenial, endocrine and metabolic disorders. Perhaps, for the future and for the next millennium the most widespread and extensive use to these anti-osteoclastic agents will be in these disorders, and particularly in so-called primary osteoporosis which evenually effects anyone who lives long enough, causing widespread morbidity with drastic economic consequences both individually and nationally. The authors' aim is to provide an office and desk companion - comprehensive, concise, practical for easy reference - an up-to-date guide for prevention and therapy of skeletal complications whenever and wherever they occur in general and specialized medical practice.



Osteoporosis An Issue Of Endocrinology And Metabolism Clinics E Book


Osteoporosis An Issue Of Endocrinology And Metabolism Clinics E Book
DOWNLOAD

Author : Sol Epstein
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-09-02

Osteoporosis An Issue Of Endocrinology And Metabolism Clinics E Book written by Sol Epstein and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-02 with Medical categories.


This issue of Endocrinology and Metabolism Clinics provides a comprehensive review of osteoporosis written by the world's leading experts. Topics include new mechanistic insights into pathophysiology; bisphosphonates; combination therapy; atypical fractures; non-BP anti resorbers; anabolic therapies; calcium; the impact of Vitamin D on bones; extraskeletal effects of Vitamin D; glucocorticoid osteoporosis; relation to anorexia nervosa, coeliac disease, and diabetes; and male osteoporosis.



Primer On The Metabolic Bone Diseases And Disorders Of Mineral Metabolism


Primer On The Metabolic Bone Diseases And Disorders Of Mineral Metabolism
DOWNLOAD

Author : Juliet E. Compston
language : en
Publisher: John Wiley & Sons
Release Date : 2009-12-22

Primer On The Metabolic Bone Diseases And Disorders Of Mineral Metabolism written by Juliet E. Compston and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-22 with Science categories.


EDITOR-IN-CHIEF: Clifford J. Rosen, M.D., Maine Medical Center Research Institute, Scarborough, Maine SENIOR ASSOCIATE EDITORS: Juliet E. Compston, M.D., FRCP, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom Jane B. Lian, Ph.D., University of Massachusetts Medical School, Worcester, Massachusetts This comprehensive yet concise handbook is an indispensable reference for the many clinicians who see patients with disorders of bone formation, metabolic bone diseases, or disorders of stone formation. It is also a crucial tool for researchers, students, and all other professionals working in the bone field. In a format designed for quick reference, it provides complete information on the symptoms, pathophysiology, diagnosis, and treatment of all common and rare bone and mineral disorders. New in this edition: detailed coverage of osteonecrosis of the jaw, more in-depth coverage of cancer and bone including new approaches to pathogenesis, diagnosis, and treatment; new approaches to anabolic therapy of osteoporosis; the latest research on Vitamin D; expanded coverage of international topics; more on the genetics of bone mass; and newer imaging techniques for the skeleton. In addition, this edition features a free, online-only appendix of medicines used to treat bone disorders and their availability around the world.