Bone Morphogenetic Proteins Systems Biology Regulators
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Bone Morphogenetic Proteins Systems Biology Regulators
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Author : Slobodan Vukicevic
language : en
Publisher: Springer
Release Date : 2017-03-14
Bone Morphogenetic Proteins Systems Biology Regulators written by Slobodan Vukicevic and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-14 with Medical categories.
This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. BMPs, also referred to as growth and differentiation factors, are members of the TGF-beta superfamily and are highly conserved from fruit flies to mammals and are responsible for the formation of practically every organ during embryo development and involved in adult tissue injury and repair. BMPs establish their extracellular gradient by interacting with their respective antagonists and regulate their function through SMAD-dependent down-stream signaling effector genes. This volume is aimed at scientists and professionals dealing with metabolic disorders, nutrition, systems biology diseases, rare musculoskeletal conditions, and disorders related to iron metabolism, including anemia of chronic disease, hereditary hemochromatosis and beta thalassemia.
Bone Morphogenetic Proteins From Local To Systemic Therapeutics
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Author : Slobodan Vukicevic
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-08-15
Bone Morphogenetic Proteins From Local To Systemic Therapeutics written by Slobodan Vukicevic and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-15 with Science categories.
Completing the PIR series, this volume summarizes the major advances made in the local and systemic use of bone morphogenetic proteins (BMPs). Chapters are dedicated to the regulation of BMP-signaling pathways; biological actions of BMPs in bone, cartilage, and teeth; clinical applications; and the potential systemic use of BMPs for tissues beyond bone. The authors are all recognized experts in the field of tissue engineering and regeneration.
Bone Morphogenetic Proteins
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Author : Slobodan Vukicevic
language : en
Publisher: Springer
Release Date : 2012-11-28
Bone Morphogenetic Proteins written by Slobodan Vukicevic and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-28 with Science categories.
From the basic science to potential and approved clinical applications the most recent data in the rapidly growing field of bone morphogenetic proteins (BMPs) are summarized in this topical volume. Distinguished scientists present reviews on a range of scientific topics, including biochemistry, biology, molecular biology and preclinical animal studies on spinal fusion, cartilage repair, craniofacial and dental reconstruction using BMPs, as well as approved clinical applications in human bone non-unions. This book provides a resource not only for experts in the field, but also for undergraduate students, newcomers and clinicians worldwide, given that the use of BMPs in orthopedic reconstruction has been already approved in Europe, Australia, Canada and the USA.
Bone Morphogenetic Proteins Regeneration Of Bone And Beyond
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Author : Slobodan Vukicevic
language : en
Publisher: Springer
Release Date : 2012-11-28
Bone Morphogenetic Proteins Regeneration Of Bone And Beyond written by Slobodan Vukicevic and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-28 with Science categories.
Since the discovery of the bone morphogenetic proteins (BMPs) more than 15 years ago, there has been an unpredicted explosion of both basic scientific discoveries and clinical reports on their use from institutions all over the world. The potent effica cy of BMPs in almost all crucial developmental events as well as during regenera tion of various organs such as bone, kidney, brain, liver, heart etc. , has positioned BMPs at the center of scientific interest. Many of these aspects are covered in this new PIR volume. Their role in development, biology, signal transduction, kidney regeneration, eNS functions, craniofacial skeleton reconstruction, joint and carti lage repair, long bone non-unions and acute fractures, and spinal fusion is reviewed by experts in the field. For the first time, the role of BMPs in carcinogenesis has been reviewed to provide a rationale for applying their biology in patients with bone tumors. The optimism resulting from safe and successful treatment with BMPs for various skeletal malformations of more than 10,000 patients worldwide has opened new avenues for exploring other indications for their use. The next big challenge for bringing BMPs to the benefit ofmankind is in regenerating articular cartilage defects and rescuing patients with acute and chronic renal failure. The volume editors thank all authors for the rapid preparation of their chapters in order that the book remains up-to-date for readers with specific interest in the field of regenerative medicine. The important contribution of Mrs. Morana and Mr.
Bone Morphogenic Protein
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-08-12
Bone Morphogenic Protein written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-12 with Science categories.
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on Bone Morphogenic Protein. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels
Principles Of Bone Biology
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Author : John P. Bilezikian
language : en
Publisher: Academic Press
Release Date : 2008-09-29
Principles Of Bone Biology written by John P. Bilezikian and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-29 with Medical categories.
Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition
Plastic Surger 6 Volume Set E Book
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Author : Peter C. Neligan
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-09-25
Plastic Surger 6 Volume Set E Book written by Peter C. Neligan and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-25 with Medical categories.
Comprehensive and fully up to date, Dr. Peter Neligan’s six-volume masterwork, Plastic Surgery, 5th Edition, remains the gold standard text in this complex area of surgery. Completely revised to meet the demands of both the trainee and experienced surgeon, it features new, full-color clinical photos, procedural videos, and lectures across all six volumes. Bonus material online includes additional text, images, and over 200 procedural videos that help you improve your mastery of the latest techniques. Easily find the answers you need with an organization that features separate volumes covering Principles • Aesthetic • Craniofacial, Head and Neck Surgery and Pediatric Plastic Surgery • Lower Extremity, Trunk and Burns • Breast • and Hand and Upper Extremity. Each easily readable, individual volume is a standalone comprehensive text full of salient and applicable anatomy and techniques. Key procedures include gender affirmation management and surgery, microsurgery and surgery for lymphedema, aesthetic facial surgery, aesthetic body surgery, and the education, training and practice of plastic surgery. New digital video preface by Dr. Neligan addresses the changes across all six volumes. New treatment and decision-making algorithms added to chapters where applicable. New video lectures and editor-narrated slide presentations offer a step-by-step audiovisual walkthrough of techniques and procedures. Four new international experts join the editorial team, and lead editor Peter C. Neligan creates a cohesive tone throughout the chapters and content across all six volumes. Evidence-based advice from a diverse collection of experts allows you to apply the very latest advances in every area of plastic surgery and ensure optimal outcomes. Purchase only the volumes you need or own the entire set, with the ability to search across all six volumes online!
Plastic Surgery
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Author : Geoffrey C Gurtner
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-08-31
Plastic Surgery written by Geoffrey C Gurtner and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-31 with Medical categories.
Comprehensive and fully up to date, the six-volume Plastic Surgery remains the gold standard text in this complex area of surgery. Completely revised to meet the demands of both the trainee and experienced surgeon, Principles, Volume 1 of Plastic Surgery, 5th Edition, features new, full-color clinical photos, procedural videos, lectures, and authoritative coverage of hot topics in the field. Editor-narrated video presentations offer a step-by-step audio-visual walkthrough of techniques and procedures. New chapters cover value-based healthcare, health services research in plastic surgery, education and teaching in plastic surgery, and gender-affirming surgery; coverage throughout includes new, pioneering translational work shaping the future of plastic surgery. New digital video preface by Dr. Peter C. Neligan addresses the changes across all six volumes. New treatment and decision-making algorithms added to chapters where applicable. New video lectures and editor-narrated slide presentations offer a step-by-step audiovisual walkthrough of techniques and procedures. Evidence-based advice from an expanded roster of international experts allows you to apply the very latest advances in plastic surgery and ensure optimal outcomes. Purchase this volume individually or own the entire set, with the ability to search across all six volumes online!
Biomaterials For Organ And Tissue Regeneration
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Author : Nihal Vrana
language : en
Publisher: Woodhead Publishing
Release Date : 2020-03-20
Biomaterials For Organ And Tissue Regeneration written by Nihal Vrana and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-20 with Medical categories.
Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects examines the use of biomaterials in applications related to artificial tissues and organs. With a strong focus on fundamental and traditional tissue engineering strategies, the book also examines how emerging and enabling technologies are being developed and applied. Sections provide essential information on biomaterial, cell properties and cell types used in organ generation. A section on state-of-the-art in organ regeneration for clinical purposes is followed by a discussion on enabling technologies, such as bioprinting, on chip organ systems and in silico simulations. Provides a systematic overview of the field, from fundamentals, to current challenges and opportunities Encompasses the classic paradigm of tissue engineering for creation of new functional tissue Discusses enabling technologies such as bioprinting, organ-on-chip systems and in silico simulations
Feedback Control In Systems Biology
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Author : Carlo Cosentino
language : en
Publisher: CRC Press
Release Date : 2011-10-17
Feedback Control In Systems Biology written by Carlo Cosentino and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-17 with Mathematics categories.
Like engineering systems, biological systems must also operate effectively in the presence of internal and external uncertainty—such as genetic mutations or temperature changes, for example. It is not surprising, then, that evolution has resulted in the widespread use of feedback, and research in systems biology over the past decade has shown that feedback control systems are widely found in biology. As an increasing number of researchers in the life sciences become interested in control-theoretic ideas such as feedback, stability, noise and disturbance attenuation, and robustness, there is a need for a text that explains feedback control as it applies to biological systems. Written by established researchers in both control engineering and systems biology, Feedback Control in Systems Biology explains how feedback control concepts can be applied to systems biology. Filling the need for a text on control theory for systems biologists, it provides an overview of relevant ideas and methods from control engineering and illustrates their application to the analysis of biological systems with case studies in cellular and molecular biology. Control Theory for Systems Biologists The book focuses on the fundamental concepts used to analyze the effects of feedback in biological control systems, rather than the control system design methods that form the core of most control textbooks. In addition, the authors do not assume that readers are familiar with control theory. They focus on "control applications" such as metabolic and gene-regulatory networks rather than aircraft, robots, or engines, and on mathematical models derived from classical reaction kinetics rather than classical mechanics. Another significant feature of the book is that it discusses nonlinear systems, an understanding of which is crucial for systems biologists because of the highly nonlinear nature of biological systems. The authors cover tools and techniques for the analysis of linear and nonlinear systems; negative and positive feedback; robustness analysis methods; techniques for the reverse-engineering of biological interaction networks; and the analysis of stochastic biological control systems. They also identify new research directions for control theory inspired by the dynamic characteristics of biological systems. A valuable reference for researchers, this text offers a sound starting point for scientists entering this fascinating and rapidly developing field.