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Brain Connectivity In Autism Spectrum Disorder


Brain Connectivity In Autism Spectrum Disorder
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Brain Connectivity In Autism


Brain Connectivity In Autism
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Author : Rajesh K. Kana
language : en
Publisher: Frontiers E-books
Release Date : 2014-09-23

Brain Connectivity In Autism written by Rajesh K. Kana and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-23 with Autism categories.


The brain's ability to process information crucially relies on connectivity. Understanding how the brain processes complex information and how such abilities are disrupted in individuals with neuropsychological disorders will require an improved understanding of brain connectivity. Autism is an intriguingly complex neurodevelopmental disorder with multidimensional symptoms and cognitive characteristics. A biological origin for autism spectrum disorders (ASD) had been proposed even in the earliest published accounts (Kanner, 1943; Asperger, 1944). Despite decades of research, a focal neurobiological marker for autism has been elusive. Nevertheless, disruptions in interregional and functional and anatomical connectivity have been a hallmark of neural functioning in ASD. Theoretical accounts of connectivity perceive ASD as a cognitive and neurobiological disorder associated with altered functioning of integrative circuitry. Neuroimaging studies have reported disruptions in functional connectivity (synchronization of activated brain areas) during cognitive tasks and during task-free resting states. While these insights are valuable, they do not address the time-lagged causality and directionality of such correlations. Despite the general promise of the connectivity account of ASD, inconsistencies and methodological differences among studies call for more thorough investigations. A comprehensive neurological account of ASD should incorporate functional, effective, and anatomical connectivity measures and test the diagnostic utility of such measures. In addition, questions pertaining to how cognitive and behavioral intervention can target connection abnormalities in ASD should be addressed. This research topic of the Frontiers in Human Neuroscience addresses “Brain Connectivity in Autism” primarily from cognitive neuroscience and neuroimaging perspectives.



Brain Connectivity In Autism Spectrum Disorder


Brain Connectivity In Autism Spectrum Disorder
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Author : Marco Catani
language : en
Publisher:
Release Date : 2012

Brain Connectivity In Autism Spectrum Disorder written by Marco Catani and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Autism categories.


In recent years Autism Spectrum Disorders (ASD) have been considered as resulting from altered connectivity between regions, which may explain characteristic manifestations in socio-emotional function, communication and repetitive behaviour observed clinically. This thesis aims to provide evidence for altered anatomy of networks in ASD. The first step consisted in the creation of a diffusion tensor tractography atlas of the normal human brain derived from 40 healthy adults. The atlas was then used to localise the findings from a meta-analysis of published voxel-based morphometry studies investigating white matter abnormalities in ASD. This analysis showed that patients with ASD display abnormalities in long white matter association tracts, such as the arcuate and uncinate fasciculus, known to be important for language and social cognition. A second step consisted in the tractography analysis of limbic and cerebellar tracts in a small pilot study. Our findings confirmed differences in the the uncinate tract in ASD and in addition we found differences in the cingulum and major intracecebellar and cerebellar output tract. Finally, Tract-Based Spatial Statistics (TBSS) and tractography analysis of a multi-centre, case-control study was performed on 61 individuals with ASD and 61 controls. Differences in the frontal connections of the arcuate fasciculus, uncinate fasciculus, cingulum and corpus callosum were found. Tract specific measurements in the arcuate and uncinate were associated with a history of delayed echolalia and impaired used efface expression in childhood, respectively. In conclusion these series of studies show that ASD are associated with specific structural abnormalities of the limbic, language and interhemispheric white matter fibres. Differences in white matter anatomy were localised in major connections to the frontal lobe and associated with specific autistic features and traits in chilldhood.



Cognitive Behavioral Therapy For Adults With Autism Spectrum Disorder Second Edition


Cognitive Behavioral Therapy For Adults With Autism Spectrum Disorder Second Edition
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Author : Valerie L. Gaus
language : en
Publisher: Guilford Publications
Release Date : 2018-12-07

Cognitive Behavioral Therapy For Adults With Autism Spectrum Disorder Second Edition written by Valerie L. Gaus and has been published by Guilford Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-07 with Medical categories.


Revision of: Cognitive-behavioral therapy for adult Asperger syndrome. c2007.



Introduction To Pattern Recognition


Introduction To Pattern Recognition
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Author : Sergios Theodoridis
language : en
Publisher: Academic Press
Release Date : 2010-03-03

Introduction To Pattern Recognition written by Sergios Theodoridis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-03 with Computers categories.


Introduction to Pattern Recognition: A Matlab Approach is an accompanying manual to Theodoridis/Koutroumbas' Pattern Recognition. It includes Matlab code of the most common methods and algorithms in the book, together with a descriptive summary and solved examples, and including real-life data sets in imaging and audio recognition. This text is designed for electronic engineering, computer science, computer engineering, biomedical engineering and applied mathematics students taking graduate courses on pattern recognition and machine learning as well as R&D engineers and university researchers in image and signal processing/analyisis, and computer vision. - Matlab code and descriptive summary of the most common methods and algorithms in Theodoridis/Koutroumbas, Pattern Recognition, Fourth Edition - Solved examples in Matlab, including real-life data sets in imaging and audio recognition - Available separately or at a special package price with the main text (ISBN for package: 978-0-12-374491-3)



Movement Control


Movement Control
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Author : Paul Cordo
language : en
Publisher: Cambridge University Press
Release Date : 1994-05-27

Movement Control written by Paul Cordo and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-05-27 with Medical categories.


Movement is arguably the most fundamental and important function of the nervous system. Purposive movement requires the coordination of actions within many areas of the cerebral cortex, cerebellum, basal ganglia, spinal cord, and peripheral nerves and sensory receptors, which together must control a highly complex biomechanical apparatus made up of the skeleton and muscles. Beginning at the level of biomechanics and spinal reflexes and proceeding upward to brain structures in the cerebellum, brainstem and cerebral cortex, the chapters in this book highlight the important issues in movement control. Commentaries provide a balanced treatment of the articles that have been written by experts in a variety of areas concerned with movement, including behaviour, physiology, robotics, and mathematics.



Neurobiology And Cognition Across The Autism Psychosis Spectrum


Neurobiology And Cognition Across The Autism Psychosis Spectrum
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Author : Tim Ziermans
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-15

Neurobiology And Cognition Across The Autism Psychosis Spectrum written by Tim Ziermans and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-15 with Medical categories.




Brain Connectivity Analysis Investigating Brain Disorders


Brain Connectivity Analysis Investigating Brain Disorders
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Author : Barry Horwitz
language : en
Publisher: Frontiers E-books
Release Date :

Brain Connectivity Analysis Investigating Brain Disorders written by Barry Horwitz and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.


In the last few years, advances in human structural and functional neuroimaging (fMRI, PET, EEG/MEG) have resulted in an explosion of studies investigating the anatomical and functional connectivity between different regions of the brain. More and more studies have employed resting and task-related connectivity analyses to assess functional interactions, and diffusion-weighted tractography to study white matter organization. Many of these studies have addressed normal human function, but recently, a number of investigators have turned their attention to examining brain disorders. The study of brain disorders is a complex endeavor; not only does it require understanding the normal brain, and the regions involved in a particular function, but also it needs a deeper understanding of brain networks and their dynamics. This Research Topic will provide the scientific community with an overview of how to apply connectivity methods to study brain disease, and with perspectives on what are the strength and limitations of each modality. For this Research Topic, we solicit both reviews and original research articles on the use of brain connectivity analysis, with non-human or human models, to explore neurological, psychiatric, developmental and neurodegenerative disorders from a system perspective. Connectivity studies that have focused on one or more of the following will be of particular interest: (1) detection of abnormal functional/structural connectivity; (2) neural plasticity, assessed by changes in connectivity, in patients with brain disorders; (3) assessment of therapy using connectivity measures; (4) relation of connectivity changes to behavioral changes.



The Neuroscience Of Autism Spectrum Disorders


The Neuroscience Of Autism Spectrum Disorders
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Author : Joseph D. Buxbaum
language : en
Publisher: Academic Press
Release Date : 2012-12-31

The Neuroscience Of Autism Spectrum Disorders written by Joseph D. Buxbaum and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Medical categories.


Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. - Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions - Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available



Autism Spectrum Disorder Within Neurodevelopmental Disorders Catching Heterogeneity Specificity And Comorbidity In Clinical Phenotypes And Neurobiological Bases


Autism Spectrum Disorder Within Neurodevelopmental Disorders Catching Heterogeneity Specificity And Comorbidity In Clinical Phenotypes And Neurobiological Bases
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Author : Eugenia Conti
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-14

Autism Spectrum Disorder Within Neurodevelopmental Disorders Catching Heterogeneity Specificity And Comorbidity In Clinical Phenotypes And Neurobiological Bases written by Eugenia Conti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-14 with Science categories.




Autism Spectrum Disorder


Autism Spectrum Disorder
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Author : Jill M. Boucher
language : en
Publisher: SAGE
Release Date : 2017-02-15

Autism Spectrum Disorder written by Jill M. Boucher and has been published by SAGE this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-15 with Psychology categories.


Following on from the popular and provocative First Edition, the Second Edition offers the latest research on autistic spectrum disorders, exploring theories at the psychological, neurobiological and 'first cause' levels to methods of assessment, intervention, education and support.