Brain Networks For Studying Healthy And Pathological Aging Mechanisms And Intervention Efficacy
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Brain Networks For Studying Healthy And Pathological Aging Mechanisms And Intervention Efficacy
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Author : Christos Frantzidis
language : en
Publisher: Frontiers Media SA
Release Date : 2020-11-18
Brain Networks For Studying Healthy And Pathological Aging Mechanisms And Intervention Efficacy written by Christos Frantzidis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-18 with Science categories.
Previous studies showed that both healthy and pathological aging are associated with changes in brain structure and function of the mature human brain. The most prominent anatomical alteration are changes in prefrontal cortex morphology, volume loss and reduced white-matter integrity and hippocampal atrophy. Cognitive decline affects mainly the performance of episodic memory, speed of sensory information processing, working memory, inhibitory function and long-term memory. It has been also proposed that due to the aforementioned changes the aging brain engages in compensatory brain mechanism such as a broader activation of cortical regions (mainly frontal) rather than specialized activation. Evidence suggests that similar changes occur with pathological aging but to a greater extent. In this case information flow is disrupted due to neurodegeneration, functional activation of posterior (occipito-temporal) regions is decreased and as a consequence the brain fails to process sensorial input in the ventral pathway and cognitive deficits appear. In the last years, functional alterations associated with aging have been studied using the mathematical notion of graph theory that offers an integrative approach since it examines different properties of the brain network: 1) Organization level 2) amount of local information processing, 3) information flow 4) cortical community structure and 5) identification of functional / anatomical hubs. So, graph theory offers an attractive way to model brain networks organization and to quantify their pathological deviations. Previous studies have already employed this mathematical notion and demonstrated that age-related neurodegeneration is often accompanied by loss of optimal network organization either due to diminished local information processing or due to progressive isolation of distant brain regions. They have also found that changes in network properties may be present even in the preclinical phase, which could be taken as a biological marker of disease.
Modifiable Risk Factors Of Accelerated Brain Aging And Dementia
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Author : Frauke Beyer
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-29
Modifiable Risk Factors Of Accelerated Brain Aging And Dementia written by Frauke Beyer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-29 with Science categories.
Cognitive Changes Of The Aging Brain
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Author : Kenneth M. Heilman
language : en
Publisher: Cambridge University Press
Release Date : 2019-12-05
Cognitive Changes Of The Aging Brain written by Kenneth M. Heilman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-05 with Medical categories.
Examines the alterations of cognition, perception, and behavior that occur with healthy brain aging, their mechanisms, and their management.
Non Pharmacological Interventions In Healthy And Pathological Aging Facts And Perspectives
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Author : Danúbia Da Cunha De Sá Caputo
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-12
Non Pharmacological Interventions In Healthy And Pathological Aging Facts And Perspectives written by Danúbia Da Cunha De Sá Caputo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-12 with Science categories.
Cholinergic Involvement In Neurodegenerative Diseases
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Author : A. Claudio Cuello
language : en
Publisher: Elsevier
Release Date : 2025-05-09
Cholinergic Involvement In Neurodegenerative Diseases written by A. Claudio Cuello and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-09 with Medical categories.
Cholinergic Involvement in Neurodegenerative Diseases, Volume 211 reviews cholinergic function in the brain as it relates to Neurodegenerative disorders. Coverage includes Alzheimer's, dementia, Down Syndrome, Parkinson's, Huntington's, ALS, and more. In addition, the anatomy of the cholinergic system is described as well as the distribution and function of receptors. - Discusses the cholinergic system as it relates to neurodegenerative diseases - Encompasses broad, comprehensive content on dementia, Alzheimer's, Parkinson's, Huntington's, ALS and more - Covers anatomy and the distribution/function of receptors
Physical Activity And The Aging Brain
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Author : Ronald Ross Watson
language : en
Publisher: Academic Press
Release Date : 2016-12-15
Physical Activity And The Aging Brain written by Ronald Ross Watson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-15 with Medical categories.
Physical Activity and the Aging Brain: Effects of Exercise on Neurological Function is a complete guide to the manifold effects of exercise and physical activity on the aging brain. Cognitive decline and motor impairment, onset of diseases and disorders, and even changes in family structure and social settings that occur as we age can all impact activity levels, yet continued physical activity is crucial for successful neurological functioning. This book examines the role that exercise and physical activity play in halting or modulating the deleterious effects of these numerous aging concerns by first examining the current state of research into how exercise manifests physical changes in the brain. It then discuss how physical activity combines with other lifestyle factors to benefit the aging brain, including nutrition, computerized brain training, and social engagement. Most significantly, it also covers how physical activity can serve as therapy to help alleviate the symptoms of various neurological diseases impacting aging populations, with particular emphasis on Alzheimer's disease and age-related cognitive decline. The book provides broad coverage of the effects of exercise and physical activity on the aging brain, its therapeutic effects, and the many factors that influence the aging process. - Presents research scientists with a complete understanding of the role of exercise in healthy brain aging - Considers the roles of nutrition, the mind-body connection, and other lifestyle factors - Presents a major resource for exercise and physical activity in the neurological health of older adults - Provides a synopsis of key ideas associated with the many aspects of physical activity, along with lifestyle factors that can modify neurological diseases and age-related neurological decline
Affective Cognitive And Social Neuroscience New Knowledge In Normal Aging Minor And Major Neurocognitive Disorders
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Author : Rosalba Morese
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-21
Affective Cognitive And Social Neuroscience New Knowledge In Normal Aging Minor And Major Neurocognitive Disorders written by Rosalba Morese and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-21 with Science categories.
Adaptive Gait And Postural Control From Physiological To Pathological Mechanisms Towards Prevention And Rehabilitation
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Author : Helena Blumen
language : en
Publisher: Frontiers Media SA
Release Date : 2020-04-06
Adaptive Gait And Postural Control From Physiological To Pathological Mechanisms Towards Prevention And Rehabilitation written by Helena Blumen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-06 with categories.
Cognitive Aging And Brain Health
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Author : Zhanjun Zhang
language : en
Publisher: Springer Nature
Release Date : 2023-07-07
Cognitive Aging And Brain Health written by Zhanjun Zhang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-07 with Medical categories.
This book reviews the research trends of cognitive aging and brain health from full-scale. It not only contains cognitive aging’s neurophysiological mechanism, clinical research and intervention measures, but also covers cognitive aging’s social psychological mechanism, such as the relation between old people’s motion, socioeconomic status and the cognitive aging. Through decades of research and practice, the views towards the cognitive aging process havebeen transferred from coping with cognitive decline to promoting cognitive ability. This book provides with the latest research findings and in-depth opinions of the cognitive aging and brain health, assisting researchers to grasp the theories, practice and trends of this field, and guide health-care workers to carry out the treatment and nursing for the aged.
Biomarkers From Multi Tracer And Multi Modal Neuroimaging In Age Related Neurodegenerative Diseases
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Author : Ping Wu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-12
Biomarkers From Multi Tracer And Multi Modal Neuroimaging In Age Related Neurodegenerative Diseases written by Ping Wu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-12 with Science categories.