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Cholinergic Involvement In Neurodegenerative Diseases


Cholinergic Involvement In Neurodegenerative Diseases
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Cholinergic Involvement In Neurodegenerative Diseases


Cholinergic Involvement In Neurodegenerative Diseases
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Author : A. Claudio Cuello
language : en
Publisher: Elsevier
Release Date : 2025-05-09

Cholinergic Involvement In Neurodegenerative Diseases written by A. Claudio Cuello and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-09 with Medical categories.


Cholinergic Involvement in Neurodegenerative Diseases, Volume 211 reviews cholinergic function in the brain as it relates to Neurodegenerative disorders. Coverage includes Alzheimer's, dementia, Down Syndrome, Parkinson's, Huntington's, ALS, and more. In addition, the anatomy of the cholinergic system is described as well as the distribution and function of receptors. - Discusses the cholinergic system as it relates to neurodegenerative diseases - Encompasses broad, comprehensive content on dementia, Alzheimer's, Parkinson's, Huntington's, ALS and more - Covers anatomy and the distribution/function of receptors



Mechanisms And Metal Involvement In Neurodegenerative Diseases


Mechanisms And Metal Involvement In Neurodegenerative Diseases
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Author : Roberta J Ward
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013-07-18

Mechanisms And Metal Involvement In Neurodegenerative Diseases written by Roberta J Ward and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-18 with Medical categories.


Dementia and neurodegenerative diseases such as Parkinson’s and Alzheimer’s are becoming an increasingly important cause of medical and social concern due to the growth in the ageing population. Mechanisms and Metal Involvement in Neurodegenerative Diseases delivers in one volume a streamlined source of information on each of the main neurodegenerative diseases including mild cognitive impairment, Parkinson's, Alzheimer's, Freiderich's ataxia, prion disease, multiple sclerosis and alcoholic brain damage. Each chapter is structured to give the definition of disease, proteins involved with structure of normal protein and abnormal proteins, pathology associated with the abnormal proteins, oxidative stress and inflammation, iron homeostatic mechanisms, primary neurotransmitter involved, other metal involvement and therapeutic strategies. Structures of the adherent protein involved in the disease process are also presented with emphasis on the chemical structures used in the treatment of each neurodegenerative disease together with their biochemical mode of action. Written by acknowledged experts in their respective areas this new book provides readers with readily accessible information on each of the neurodegenerative diseases.



Neuroscience For Clinicians


Neuroscience For Clinicians
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Author : Eduardo E. Benarroch
language : en
Publisher: Oxford University Press
Release Date : 2021

Neuroscience For Clinicians written by Eduardo E. Benarroch and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Medical categories.


This book with provide clinicians with focused reviews on basic sciences to help understanding the mechanisms and treatment of neurologic disease. The chapters emphasize how genetic, molecular and cellular, mechanisms and their interactions control the function of the nervous system and provide the bases for a wide range of neurologic disorders. They include neurodegenerative disorders, epilepsy, movement disorders, peripheral neuropathy, and chronic pain, among others. The chapters contains several figures and tables that summarize the most important concepts



Text Book Of Medicinal Chemistry I


Text Book Of Medicinal Chemistry I
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Author : Dr. Prabhat Kumar Upadhyay, Dr. Narsukumari Korrapati, Dr Pichika Mallikarjuna Rao, Dr Balijepalli Madhu Katyayani, Dr. Mak Kit-Kay, Dr.Vishal Trivedi
language : en
Publisher: Shashwat Publication
Release Date : 2025-05-31

Text Book Of Medicinal Chemistry I written by Dr. Prabhat Kumar Upadhyay, Dr. Narsukumari Korrapati, Dr Pichika Mallikarjuna Rao, Dr Balijepalli Madhu Katyayani, Dr. Mak Kit-Kay, Dr.Vishal Trivedi and has been published by Shashwat Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-31 with Fiction categories.


The Text Book of Medicinal Chemistry-I is a foundational academic resource tailored for undergraduate pharmacy and life science students. It begins with an insightful introduction to the history and development of medicinal chemistry, followed by an exploration of essential physicochemical properties—such as ionization, solubility, partition coefficient, and bioisosterism—that influence drug action. The book delves into drug metabolism, explaining both Phase I and Phase II reactions and emphasizing the stereochemical aspects affecting biotransformation. A significant portion is dedicated to the autonomic nervous system, detailing adrenergic and cholinergic neurotransmitters, their biosynthesis, metabolism, receptors, and drug interactions. Comprehensive coverage is given to sympathomimetic agents and adrenergic antagonists, including their classification, mechanism of action, and SAR. The cholinergic section spans both parasympathomimetic agents and cholinergic blockers, thoroughly explaining their pharmacological and structural aspects. Sedatives and hypnotics such as benzodiazepines and barbiturates are analyzed for their therapeutic role and SAR. Antipsychotic drugs, including phenothiazine derivatives and newer analogs, are presented with clarity. The anticonvulsant chapter includes barbiturates, hydantoins, and newer agents like gabapentin and valproic acid, along with mechanisms and SAR. The text also explains the classification and use of general anesthetics, including inhalation agents and dissociative anesthetics like ketamine. In-depth sections cover narcotic and non-narcotic analgesics, their SAR, mechanism, and therapeutic uses. It emphasizes both opioid agonists and antagonists, such as morphine and naloxone. The final chapter provides detailed information on anti-inflammatory drugs, including NSAIDs like aspirin, ibuprofen, and diclofenac. Throughout, the book emphasizes structure-activity relationships (SAR), mechanisms of action, and pharmacological applications. With drug examples and classifications well-integrated, this book provides a practical, application-oriented approach to medicinal chemistry. It is designed to help students connect chemical structures with pharmacological effects. Each chapter encourages critical thinking about how molecular features influence drug behavior. The text is organized logically, facilitating step-by-step learning of complex concepts. Additionally, it bridges the gap between basic science and clinical pharmacy, making it ideal for academic and exam preparation..



Encyclopedia Of Psychopharmacology


Encyclopedia Of Psychopharmacology
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Author : Ian Stolerman
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-07-31

Encyclopedia Of Psychopharmacology written by Ian Stolerman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-31 with Medical categories.


Here is a broad overview of the central topics and issues in psychopharmacology, biological psychiatry and behavioral neurosciences, with information about developments in the field, including novel drugs and technologies. The more than 2000 entries are written by leading experts in pharmacology and psychiatry and comprise in-depth essays, illustrated with full-color figures, and are presented in a lucid style.



Molecular Imaging Of Neurodegenerative Disorders


Molecular Imaging Of Neurodegenerative Disorders
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Author : Donna J. Cross
language : en
Publisher: Springer Nature
Release Date : 2023-09-26

Molecular Imaging Of Neurodegenerative Disorders written by Donna J. Cross and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-26 with Medical categories.


This book provides a comprehensive review of the role of molecular imaging in neurodegenerative diseases. A growing field, molecular imaging of neurodegeneration is becoming increasingly relevant with an aging population, and this book serves to provide both an introduction to the concept and background of neurodegeneration and an update on the most recent imaging advances. Throughout, chapters will review current applications of neuroimaging in neurodegenerative disorders, like dementia and movement disorders, and increase knowledge of quantification and semi-quantification methods for neuroimaging. Imaging methods such as PET/CT and PET/MR are covered, as well as more advanced technologies like artificial intelligence algorithms and novel radiotracers. Chapters are also intended to improve competency in reporting and interpretation skills with structured information on current practice. The book concludes with a collection of up to date practice cases for the interpretation of neurodegeneration in nuclear medicine imaging. This is an ideal guide for nuclear medicine physicians, neuroradiologists, neurologists, residents, trainees, and related medical professionals caring for patients with neurodegeneration.



Cholinergic Basis For Alzheimer Therapy


Cholinergic Basis For Alzheimer Therapy
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Author : Ezio Giacobini
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21

Cholinergic Basis For Alzheimer Therapy written by Ezio Giacobini and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Social Science categories.




Hybrid Pet Mr Neuroimaging


Hybrid Pet Mr Neuroimaging
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Author : Ana M. Franceschi
language : en
Publisher: Springer Nature
Release Date : 2021-11-30

Hybrid Pet Mr Neuroimaging written by Ana M. Franceschi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-30 with Medical categories.


This book serves as a reference and comprehensive guide for PET/MR neuroimaging. The field of PET/MR is rapidly evolving, however, there is no standard resource summarizing the vast information and its potential applications. This book will guide neurological molecular imaging applications in both clinical practice and the research setting. Experts from multiple disciplines, including radiologists, researchers, and physicists, have collaborated to bring their knowledge and expertise together. Sections begin by covering general considerations, including public health and economic implications, the physics of PET/MR systems, an overview of hot lab and cyclotron, and radiotracers used in neurologic PET/MRI. There is then coverage of each major disease/systemic category, including dementia and neurodegenerative disease, epilepsy localization, brain tumors, inflammatory and infectious CNS disorders, head and neck imaging, as well as vascular hybrid imaging. Together, we have created a thorough, concise and up-to-date textbook in a unique, user-friendly format. This is an ideal guide for neuroradiologists, nuclear medicine specialists, medical physicists, clinical trainees and researchers.



Basic Neurosciences With Clinical Applications


Basic Neurosciences With Clinical Applications
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Author : Eduardo E. Benarroch
language : en
Publisher: Elsevier Health Sciences
Release Date : 2006-01-01

Basic Neurosciences With Clinical Applications written by Eduardo E. Benarroch and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-01 with Medical categories.


This single-author book covers basic aspects of neuroscience, including concepts of molecular biology, neurochemistry, and electrophysiology, and makes direct clinical correlations in a concise and coherent manner. This concise, coherent text provides a link between basic science and clinical correlations.Readers will benefit from the author's expertise as an academic clinical neurologist.This text provides a concise review of basic neuroscience concepts that are included in several qualifying examinations, including the National Boards.



Aging And Dementia


Aging And Dementia
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Author : Erik Johan Anton Scherder
language : en
Publisher: VU Uitgeverij
Release Date : 2011

Aging And Dementia written by Erik Johan Anton Scherder and has been published by VU Uitgeverij this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Health & Fitness categories.


Drawing on the most current research, this study is the perfect companion for those who work alongside elderly people with and without dementia. The book explains why changes in cognition, motor skills, and pain are typical for the elderly while describing the most prevalent subtypes of dementia, including Alzheimer's disease, vascular dementia, and frontotemporal dementia. Focusing on the motor skills of hand motor activity and gait, the study also illustrates changes in the various aspects of pain experience, explaining them clearly through the use of neuropathology of the medial and lateral pain systems. Updates concerning compensation and rehabilitation are also included.