Burden Epidemiology Of Respi
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Burden Epidemiology Of Respi
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Author : Lan Wei
language : en
Publisher: Open Dissertation Press
Release Date : 2017-01-26
Burden Epidemiology Of Respi written by Lan Wei and has been published by Open Dissertation Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-26 with Medical categories.
This dissertation, "Burden and Epidemiology of Respiratory Viruses in Hong Kong" by Lan, Wei, 衞蘭, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Respiratory viral infections (RVIs) cause a substantial burden of morbidity and mortality among children worldwide, particularly in children age under five years of age. However, vaccination, as the optimal means of disease prevention, is currently not available for most respiratory viruses. Apart from influenza virus (IFV) and respiratory syncytial virus (RSV), the epidemiology and disease burden of many RVIs have not been comprehensively studied. I investigated the etiology, seasonality and other epidemiology features of respiratory viral infections in Hong Kong children based on a series of datasets from ill children in the general community, from outpatient clinics, and from hospitals. I also used population-based mortality and morbidity data. I fitted statistical models to the data to characterize the seasonality and examine the correlation of seasonal patterns with climactic factors. I used regression models to estimate excess hospitalizations and mortality. I assessed the severity by comparing statistical estimates of the impact of each disease at different levels of the pyramid of disease. I found that entero/rhinoviruses, influenza viruses and coronaviruses were more frequently detected among all children regardless of symptoms, with human metapneumovirus also more commonly detected in symptomatic children and parainfluenza virus among those asymptomatic children. The overall duration of symptoms of those with positive detection of a respiratory virus was about 8.2 days. Clinical characteristics of these respiratory viruses were similar except for significant difference in fever, cough and mean age. Younger children (aged 0-5 years) had a higher frequency of virus detection and a longer symptomatic duration than the older children (aged 6-15 years). All non-influenza viruses together(RSV: 182, CI: 95-269; PIV,122, CI:34-209; AdV, 120, CI: 43-201) were associated with an estimated 423 excess respiratory hospitalizations per 100,000 person-years, similar to those caused by influenza viruses (422, CI: 341-501) in children. Common respiratory viruses were associated with 0.21 to 4.35 excess respiratory intensive care unit (ICU) admissions per 100,000 person-years, with 3.54 for influenza virus and 9.11 for all non-influenza viruses together. None of the viruses were associated with significant excess mortality except for influenza A (H1N1) (0.11 per 100,000 person-years). Both influenza and non-influenza respiratory virus infections were associated with substantial diseases burden in Hong Kong children. IFV and RSV contributed to the highest excess hospitalization and ICU admission rate. The risk of hospital to ICU admission was generally higher for non-influenza virus infections than IFV infections. In conclusion, the impact and severity of respiratory viruses was greater in younger children compared to older children. Significant disease burden caused by non-influenza viruses underscores the importance of control of respiratory virus infections in children beyond influenza vaccination. Subjects: Respiratory infections - China - Hong Kong Virus diseases - China - Hong Kong
Burden And Epidemiology Of Respiratory Viruses In Hong Kong
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Author : Lan Wei
language : en
Publisher:
Release Date : 2017-01-26
Burden And Epidemiology Of Respiratory Viruses In Hong Kong written by Lan Wei and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-26 with Respiratory infections categories.
Tackling The Burden Of Respiratory Viruses
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Author : Kaat Ramaekers (Doctor in Biomedical Sciences)
language : en
Publisher:
Release Date : 2021
Tackling The Burden Of Respiratory Viruses written by Kaat Ramaekers (Doctor in Biomedical Sciences) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Respiratory Epidemiology
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Author : Isabella Annesi-Maesano
language : en
Publisher: European Respiratory Society
Release Date : 2014-09-01
Respiratory Epidemiology written by Isabella Annesi-Maesano and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-01 with Medical categories.
Over the last decade, the volume of research into the pathophysiology and genetics of pulmonary diseases has increased greatly. This has led to the development of new treatments and therapies for many diseases, including lung cancer, asthma and cystic fibrosis. This issue of the ERS Monograph comprehensively demonstrates the developments in respiratory medicine in recent years. It outlines the importance of epidemiology in respiratory medicine, and will prove a methodological tool that will help disease management. It should also be used as an advocacy tool for the sake of public health.
Disease And Mortality In Sub Saharan Africa
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Author : Dean T. Jamison
language : en
Publisher: World Bank Publications
Release Date : 2006-01-01
Disease And Mortality In Sub Saharan Africa written by Dean T. Jamison and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-01 with Medical categories.
Current data and trends in morbidity and mortality for the sub-Saharan Region as presented in this new edition reflect the heavy toll that HIV/AIDS has had on health indicators, leading to either a stalling or reversal of the gains made, not just for communicable disorders, but for cancers, as well as mental and neurological disorders.
Pediatric Respiratory Diseases
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Author : Pablo Bertrand
language : en
Publisher: Springer Nature
Release Date : 2020-01-31
Pediatric Respiratory Diseases written by Pablo Bertrand and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-31 with Medical categories.
This is a comprehensive and authoritative textbook on pediatric pulmonology. Edited by Pablo Bertrand and Ignacio Sánchez, renowned academics and pediatricians from the Pontifical Catholic University of Chile, it encompasses five sections and 74 chapters, presenting and discussing the most important topics related to pediatric respiratory diseases. Written and presented in a simple and didactic format, it intends to ease learning and settlement of doubts in pediatric respiratory diseases. The reader is naturally introduced into the physiology, diagnosis, syndromes, diseases and the treatment associated with the respiratory pathologies affecting children. The chapters include algorithms for the treatment of various syndromes and updated treatment proposals grounded in evidence-based medicine for more than 50 pulmonary diseases. Pediatric Respiratory Diseases – A Comprehensive Textbook is an essential reference for the proper clinical approach to respiratory diseases in children. It is intended for all interns, residents and fellows with interest in pediatric pulmonary medicine, as well as practicing physicians, general practitioners, pediatricians and pulmonologists who face pediatric respiratory disorders in daily clinical practice.
Sars Mers And Other Viral Lung Infections
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Author : David S. Hui
language : en
Publisher: European Respiratory Society
Release Date : 2016-06-01
Sars Mers And Other Viral Lung Infections written by David S. Hui and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-01 with Medical categories.
Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.
The Global Impact Of Respiratory Disease
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Author : Darcy D. Marciniuk
language : en
Publisher:
Release Date : 2017
The Global Impact Of Respiratory Disease written by Darcy D. Marciniuk and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Disease Control Priorities In Developing Countries
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Author : Dean T. Jamison
language : en
Publisher: World Bank Publications
Release Date : 2006-04-02
Disease Control Priorities In Developing Countries written by Dean T. Jamison and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-02 with Medical categories.
Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.
Disease Control Priorities Third Edition Volume 5
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Author : Dorairaj Prabhakaran
language : en
Publisher: World Bank Publications
Release Date : 2017-11-17
Disease Control Priorities Third Edition Volume 5 written by Dorairaj Prabhakaran and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-17 with Medical categories.
Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.