C H And C X Bond Functionalization


C H And C X Bond Functionalization
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C H And C X Bond Functionalization


C H And C X Bond Functionalization
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Author : Xavi Ribas
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013-05-24

C H And C X Bond Functionalization written by Xavi Ribas and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Science categories.


Cross-coupling reactions involving C-H and C-X bond functionalisation are commonplace in natural product synthesis and natural products, therapeutic agents, biological probes, and advanced materials. Much attention has been given to understanding the mechanistic strategies used to achieve this, making this a hot topic in recent years. In this edited book, contributions from across the globe examine these strategies, with a particular focus on palladium and copper, as well as iron – an emerging element in this field. Reviewing the recent literature, the book presents an in-depth understanding of the field, guiding the reader to achieving the best synthetic strategies for aromatic functionalisation. Organic and Organometallic chemists, as well as natural product and pharmaceutical scientists, will find this an essential guide to a major transformation currently underway in synthetic chemistry.



Pincer And Pincer Type Complexes


Pincer And Pincer Type Complexes
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Author : Kálmán J. Szabó
language : en
Publisher: John Wiley & Sons
Release Date : 2014-06-10

Pincer And Pincer Type Complexes written by Kálmán J. Szabó and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-10 with Science categories.


This new book on this hot topic summarizes the key achievements for the synthesis and catalytic applications of pincer and pincer-type complexes, providing readers with the latest research highlights. The editors have assembled an international team of leaders in the field, and their contributions focus on the application of various pincer complexes in modern organic synthesis and catalysis, such as C-C and C-X bond forming reactions, C-H bond functionalization, and the activation of small molecules, as well as asymmetric catalysis. A must-have for every synthetic chemist in both academia and industry intending to develop new catalysts and improved synthetic protocols.



C X Bond Formation


C X Bond Formation
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Author : Arkadi Vigalok
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-07-09

C X Bond Formation written by Arkadi Vigalok and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-09 with Science categories.


Contents: Kilian Muñiz: Transition Metal Catalyzed Electrophilic Halogenation of C-H bonds in alpha-Position to Carbonyl Groups; Arkadi Vigalok * and Ariela W Kaspi: Late Transition Metal-Mediated Formation of Carbon-Halogen Bonds; Paul Bichler and Jennifer A. Love*: Organometallic Approaches to Carbon-Sulfur Bond Formation; David S. Glueck: Recent Advances in Metal-Catalyzed C-P Bond Formation; Andrei N. Vedernikov: C-O Reductive Elimination from High Valent Pt and Pd Centers; Lukas Hintermann: Recent Developments in Metal-Catalyzed Additions of Oxygen Nucleophiles to Alkenes and Alkynes; Moris S. Eisen: Catalytic C-N, C-O and C-S bond formation promoted by organoactinide complexes.



Oxidative Cross Coupling Reactions


Oxidative Cross Coupling Reactions
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Author : Aiwen Lei
language : en
Publisher: John Wiley & Sons
Release Date : 2016-08-17

Oxidative Cross Coupling Reactions written by Aiwen Lei and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-17 with Technology & Engineering categories.


The first handbook on this emerging field provides a comprehensive overview of transition metal-catalyzed coupling reactions in the presence of an oxidant. Following an introduction to the general concept and mechanism of this reaction class, the team of authors presents chapters on C-C cross-coupling reactions using organometallic partners, C-Heteroatom bond forming reactions via oxidative couplings, and C-H couplings via C-H activation. The text also covers such groundbreaking topics as recent achievements in the fields of C-C and C-X bond formation reactions as well as C-H activation involving oxidative couplings. With its novel and concise approach towards important building blocks in organic chemistry and its focus on synthetic applications, this handbook is of great interest to all synthetic chemists in academia and industry alike.



Non Noble Metal Catalysis


Non Noble Metal Catalysis
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Author : Robertus J. M. Klein Gebbink
language : en
Publisher: John Wiley & Sons
Release Date : 2018-12-31

Non Noble Metal Catalysis written by Robertus J. M. Klein Gebbink and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-31 with Technology & Engineering categories.


An expert overview of current research, applications, and economic and environmental advantages The study and development of new homogeneous catalysts based on first-row metals (Mn, Fe, Co, Ni, and Cu) has grown significantly due to the economic and environmental advantages that non-noble metals present. Base metals offer reduced cost, greater supply, and lower toxicity levels than noble metals?enabling greater opportunity for scientific investigation and increased development of practical applications. Non-Noble Metal Catalysis provides an authoritative survey of the field, from fundamental concepts and computational methods to industrial applications and reaction classes. Recognized experts in organometallic chemistry and homogeneous catalysis, the authors present a comprehensive overview of the conceptual and practical aspects of non-noble metal catalysts. Examination of topics including non-innocent ligands, proton-coupled electron transfer, and multi-nuclear complexes provide essential background information, while areas such as kinetic lability and lifetimes of intermediates reflect current research and shifting trends in the field. This timely book demonstrates the efficacy of base metal catalysts in the pharmaceutical, fine-chemical, and agrochemical industries, addressing both environmental and economic concerns. Providing essential conceptual and practical exploration, this valuable resource: -Illustrates how unravelling new reactivity patterns can lead to new catalysts and new applications -Highlights the multiple advantages of using non-noble metals in homogenous catalysis -Demonstrates how the availability of non-noble metal catalysis reduces costs and leads to immense savings for the chemical industry -Reveals how non-noble metal catalysis are more sustainable than noble metals such as palladium or platinum Non-Noble Metal Catalysis: Molecular Approaches and Reactions is an indispensable source of up-to-date information for catalytic chemists, organic chemists, industrial chemists, organometallic chemists, and those seeking to broaden their knowledge of catalytic chemistry.



Green And Sustainable Medicinal Chemistry


Green And Sustainable Medicinal Chemistry
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Author : Louise Summerton
language : en
Publisher: Royal Society of Chemistry
Release Date : 2016-03-08

Green And Sustainable Medicinal Chemistry written by Louise Summerton and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-08 with Science categories.


Pharmaceutical manufacturing was one of the first industries to recognize the importance of green chemistry, with pioneering work including green chemistry metrics and alternative solvents and reagents. Today, other topical factors also have to be taken into consideration, such as rapidly depleting resources, high energy costs and new legislation. This book addresses current challenges in modern green chemical technologies and sustainability thinking. It encompasses a broad range of topics covered by the CHEM21 project – Europe’s largest public-private partnership project which aims to develop a toolbox of sustainable technologies for green chemical intermediate manufacture. Divided into two sections, the book first gives an overview of the key green chemistry tools, guidance and considerations aimed at developing greener processes, before moving on to look at cutting-edge synthetic methodologies. Featuring innovative research, this book is an invaluable reference for chemists across academia and industry wanting to further their knowledge and understanding of this important topic.



Palladium Catalyzed Modification Of Nucleosides Nucleotides And Oligonucleotides


Palladium Catalyzed Modification Of Nucleosides Nucleotides And Oligonucleotides
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Author : Anant R. Kapdi
language : en
Publisher: Elsevier
Release Date : 2018-06-04

Palladium Catalyzed Modification Of Nucleosides Nucleotides And Oligonucleotides written by Anant R. Kapdi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-04 with Science categories.


Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides describes the procedures and protocols related to the modification of nucleosides, nucleotides and oligonucleotides via Pd-mediated cross-coupling processes. The book highlights the growing area of nucleic acid modification and how Pd-mediated coupling reactions can assist this development. Users will find key synthetic protocols for these reactions in this latest volume in the Latest Trends in Palladium Chemistry series. As most of the research in the field of antiviral agents has centered on the use of modified nucleosides that have exhibited promising activity, this book provides an up-to-date reference for both professionals in industry and other interested parties. Provides synthetic routes for useful nucleoside molecules, information otherwise found only through time-consuming literature searches Covers metal-mediated and metal-catalyzed cross coupling processes of nucleosides and related compounds Includes Suzuki-Miyaura, Stille and Sonogashira reactions, as well as C-H bond functionalization Highlights the growing area of nucleic acid modification and how Pd-mediated coupling reactions can assist



Heterocycles From Double Functionalized Arenes


Heterocycles From Double Functionalized Arenes
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Author : Xiao-Feng Wu
language : en
Publisher: Royal Society of Chemistry
Release Date : 2015-02-02

Heterocycles From Double Functionalized Arenes written by Xiao-Feng Wu and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-02 with Science categories.


The efficient synthesis of heterocycles has become one of the main branches in organic chemistry due to their use in the synthesis of natural products and pharmaceuticals. Current sythentic strategies based on C-H activation methodologies are met with many problems like harsh reaction conditions and low reaction efficiency. Double functionalized chemicals offer a perfect alternative for the synthesis of heterocycles. Heterocycles from Double-Functionalized Arenes starts with a short discussion on the importance of heterocycles and a brief introduction on the preparation of double-functionalized arenes. Specific chapters then look at five-membered heterocycles synthesis, six-membered heterocycles synthesis and macroheterocycles synthesis. This is the first book dedicated to the topic of transition metal catalyzed coupling reactions of double functionalized arenes in heterocycle synthesis and can be used as a handbook for senior researchers and as an introduction for organic chemistry students.



Transition Metal Catalyzed Oxidative Cross Coupling Reactions


Transition Metal Catalyzed Oxidative Cross Coupling Reactions
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Author : Aiwen Lei
language : en
Publisher: Springer
Release Date : 2018-12-14

Transition Metal Catalyzed Oxidative Cross Coupling Reactions written by Aiwen Lei and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-14 with Science categories.


This book is a comprehensive text covering the research and development trends in the booming field of transition metal catalyzed oxidative cross-coupling reactions. Oxidative cross-coupling reaction is a new method to forming chemical bonds besides the traditional cross-coupling reactions. This book provides the answers to how this coupling reaction occurs and what its advantages are. The palladium, copper and iron catalyzed oxidative cross-coupling reactions as the main focuses of interest are described in detail. The oxidative cross-coupling reactions catalyzed by other metals and transition-metal-free oxidative coupling reactions are also introduced.This book provides a useful reference source for researchers and graduates in the field of transition metal catalyzed coupling reactions. It is also valuable to researchers working in pharmaceutical companies, fine organic chemical companies, and etc.



Asymmetric Functionalization Of C H Bonds


Asymmetric Functionalization Of C H Bonds
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Author : Shu-Li You
language : en
Publisher: Royal Society of Chemistry
Release Date : 2015-07-30

Asymmetric Functionalization Of C H Bonds written by Shu-Li You and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-30 with Science categories.


Asymmetric C-H direct functionalization reactions are one of the most active and fascinating areas of research in organic chemistry due to their significance in the construction of molecular complexity without pre-activation, and the step economy and atom economy features in potential synthetic application. Distinguishing the reactivity among numerous C–H bonds in one single molecule represents one of the most challenging issues in organic synthesis and requires precise reaction design. As such, this field is now receiving increasing attention from researchers. This book provides the first comprehensive review of this field, summarizing the origin, mechanism, scope and applications of the asymmetric C-H bond functionalization reaction. It covers organocatalytic reactions and transition-metal-catalyzed reactions, as well as asymmetric C-H functionalization reactions not described in other books. Written by a leading expert in this field, the book is ideal for postgraduates and researchers working in organic synthesis, catalysis, and organometallic chemistry.