Calcific Aortic Valve Disease
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Calcific Aortic Valve Disease
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Author : Elena Aikawa
language : en
Publisher: BoD – Books on Demand
Release Date : 2013-06-12
Calcific Aortic Valve Disease written by Elena Aikawa and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-12 with Medical categories.
Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.
Developmental And Acquired Mechanisms Of Calcific Aortic Valve Disease
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Author : Joy Lincoln
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-01
Developmental And Acquired Mechanisms Of Calcific Aortic Valve Disease written by Joy Lincoln and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-01 with Medical categories.
From Biology To Clinical Management An Update On Aortic Valve Disease 2nd Edition
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Author : Cécile Oury
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-04
From Biology To Clinical Management An Update On Aortic Valve Disease 2nd Edition written by Cécile Oury and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-04 with categories.
Calcific aortic valve stenosis is the most frequent valvular heart disease in Western countries, affecting up to 13% of individuals over 75 years. The disease is associated with considerable morbidity and mortality. It is characterized by fibro-calcification of aortic valve cusps and concomitant left ventricular remodelling due to chronic pressure overload, which can evolve into overt heart failure. It progresses very slowly until the onset of symptoms, the indication for aortic valve replacement. Today, about 300,000 aortic valve replacements are performed annually worldwide, either via surgery or transcatheter implantation. This is the only treatment shown to improve survival. There is no pharmacological treatment to prevent or slow disease progression. Major risk factors include older age, congenital anomalies of the aortic valve (bicuspid valve), male gender, hypertension, dyslipidaemia, smoking, and diabetes. However, how these factors contribute to the disease in unclear. Due to the disease itself, patients are at increased risk of both thrombosis and bleeding, which, in addition to advanced age and comorbidities, makes antithrombotic management of these patients difficult. Regarding valve prostheses, the ideal prosthesis either mechanical or biological still does not exist. Clinically available prostheses can lead to major complications, thrombosis or infection, which necessitate reoperation or cause death in 50-60% of patients within 10 years post-implantation. Hence, there are major unmet medical needs in CAVS and more basic and translational research is definitely required. Our Research Topic depicts major challenges and research paths that could be followed to address these major health needs.
Aortic Valve
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Author : Chen Ying-Fu
language : en
Publisher: IntechOpen
Release Date : 2011-12-09
Aortic Valve written by Chen Ying-Fu and has been published by IntechOpen this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-09 with Medical categories.
Much has evolved in the field of aortic valve disease because of the increase in knowledge in the last decade, especially in the area of its management. This book "Aortic Valve" is comprised of 18 chapters covering basic science, general consideration of aortic valve disease, infective endocarditis, aortic sclerosis and aortic stenosis, bioprosthetic valve, transcatheter aortic valve implantation and a special section on congenital anomalies of the aortic valve. We hope this book will be particularly useful to cardiologists and cardiovascular surgeons and trainees. We also believe that this book will be a valuable resource for radiologists, pathologists, cardiovascular anesthesiologists, and other healthcare professionals who have a special interest in treating patients with aortic valve disease. We are certain that information in this book will help to provide virtually most new areas of aortic valve disease that will be employed in the current era.
Advances In Calcific Aortic Valve Disease Research
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Author : Samuel Ostroff
language : en
Publisher:
Release Date : 2015-03-24
Advances In Calcific Aortic Valve Disease Research written by Samuel Ostroff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-24 with categories.
Calcific aortic valve disease (CAVD) is one of the most common forms of valve disease. It has become the most widespread cardiac valve disease in the economically advanced nations. Population ageing is one of the major reasons for this increasing rate. Th
Cardiac Valvular Medicine
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Author : Nalini M. Rajamannan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-14
Cardiac Valvular Medicine written by Nalini M. Rajamannan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-14 with Medical categories.
The book will be written by the experts in the disease including imaging, interventional cardiology and surgical valve expertise. The book has five main sections: Aortic Valve Disease Mitral Valve Disease Tricuspid Valve Disease Pulmonic Valve Disease Multimodality Imaging The main objectives of the book are: 1- to provide the main guidelines to clinicians on how to identify and diagnose valvular heart disease 2- to provide an overview of what the near future will bring in the diagnosis, prevention and risk stratification of patients to catheter versus surgical approaches 3- to outline the possible implications for medical therapies in slowing progression of calcific aortic valve disease and myxomatous mitral valve disease
Osteocardiology
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Author : Nalini M. Rajamannan
language : en
Publisher: Springer
Release Date : 2017-10-24
Osteocardiology written by Nalini M. Rajamannan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-24 with Medical categories.
This book describes the field of osteocardiology, an exciting and new sub-discipline within cardiovascular science, which will become the cornerstone for defining the timing and treatment of cardiovascular calcification in the future. With the advent of large cohort databases and experimental mechanistic studies, research has elucidated evidence confirming that traditional cardiovascular risk factors are responsible for the development of atherosclerotic calcification and identified the critical elements of atherosclerosis, including foam cell formation, vascular smooth muscle cell proliferation and extracellular matrix synthesis, which over time forms bone in the heart. Osteocardiology: Cardiac Bone Formation is a practical overview of bone formation in the heart and is destined to become the cornerstone for education of medical students, residents, fellows, graduate students, physician scientists and scientists, for future research and ongoing development in medical therapies to slow or halt the progression of bone formation in the heart.
Cardiovascular Imaging
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Author : Elena Aikawa
language : en
Publisher: Springer
Release Date : 2014-11-03
Cardiovascular Imaging written by Elena Aikawa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-03 with Medical categories.
This book provides comprehensive reviews on our most recent understanding of the molecular and cellular mechanisms underlying atherosclerosis and calcific aortic valve disease (CAVD) as visualized in animal models and patients using optical molecular imaging, PET-CT, ultrasound and MRI. In addition to presenting up-to-date information on the multimodality imaging of specific pro-inflammatory or pro-calcification pathways in atherosclerosis and CAVD, the book addresses the intriguing issue of whether cardiovascular calcification is an inflammatory disease, as has been recently supported by several preclinical and clinical imaging studies. In order to familiarize researchers and clinicians from other specialties with the basic mechanisms involved, chapters on the fundamental pathobiology of atherosclerosis and CAVD are also included. The imaging chapters, written by some of the foremost investigators in the field, are so organized as to reveal the nature of the involved mechanisms as disease progresses.
Aortic Stenosis
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Author : Masanori Hirota
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-10-10
Aortic Stenosis written by Masanori Hirota and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-10 with Medical categories.
Currently, aortic stenosis (AS) is the most prevalent valvular disease in developed countries. Pathological and molecular mechanisms of AS have been investigated in many aspects. And new therapeutic devices such as transcatheter aortic valve implantation have been developed as a less invasive treatment for high-risk patients. Due to advanced prevalent age of AS, further discovery and technology are required to treat elderly patients for longer life expectancy. This book is an effort to present an up-to-date account of existing knowledge, involving recent development in this field. Various opinion leaders described details of established knowledge or newly recognized advances associated with diagnosis, treatment and mechanism. Thus, this book will enable close intercommunication to another field and collaboration technology for new devices. We hope that it will be an important source, not only for clinicians, but also for general practitioners, contributing to development of better therapeutic adjuncts in the future.
Targeted Drug Discovery In Ectopic Calcification Mechanism Prospect And Clinical Application
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Author : Kang Xu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-26
Targeted Drug Discovery In Ectopic Calcification Mechanism Prospect And Clinical Application written by Kang Xu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-26 with Science categories.