Calcium Vitamin D And Prevention Of Colon Cancer
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Calcium Vitamin D And Prevention Of Colon Cancer
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Author : Martin Lipkin
language : en
Publisher: CRC Press
Release Date : 2018-01-18
Calcium Vitamin D And Prevention Of Colon Cancer written by Martin Lipkin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Medical categories.
These proceedings were published as a result of a workshop sponsored by the Chemoprevention Branch of the National Cancer Institute. The workshop covered a range of topics including calcium and vitamin D in human nutrition; epidemiologic relationships betweencalcium, vitamin D, and colon cancer; the biology of calium and vitamin D at the tissue and cellular level; and enimal and human studies investigating the potential for prevention of colon cancer with calcium and vitamin D.
Vitamin D Analogs In Cancer Prevention And Therapy
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Author : J. Reichrath
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Vitamin D Analogs In Cancer Prevention And Therapy written by J. Reichrath and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Medical categories.
A comprehensive, highly readable overview of the topics discussed at the First International Symposium on "Vitamin D Analogs in Cancer Prevention and Therapy" held in Homburg/Saar, Germany in May 2002. Leading researchers discuss our present knowledge of the vitamin D system in cancer. Topics range from the newest findings in molecular biology, epidemiology, synthesis and metabolism of vitamin D to new concepts for the use of vitamin D analogs in cancer prophylaxis and treatment. The book provides essential up-to-date information for every researcher or clinician interested in the biology of vitamin D or cancer.
Vitamin D And Cancer
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Author : Donald L. Trump
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-09
Vitamin D And Cancer written by Donald L. Trump and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-09 with Medical categories.
Substantial data indicate the broad importance of vitamin D-based signaling in normal human physiology and the broad effects of vitamin D deficiency. Vitamin D may play a role not only in the control of bone and mineral metabolism, but also appears to be involved in immune function, cardiovascular health, thrombosis and vasculogenesis and neuromuscular function. Considerable epidemiologic data demonstrate that low vitamin D serum levels occur very commonly in normal adult populations and that vitamin D deficiency is associated with an enhanced risk of cancer death from lung, prostate, head & neck, colorectal and other gastrointestinal cancers. In addition, preclinical data provide evidence that calcitriol and other active analogues of calcitriol have anti-proliferative, pro-differentiative, pro-apoptotic and anti-angiogenic activity in numerous in-vitro and in-vivo models. It is quite clear that, while it requires high exposure to calcitriol to induce these effects, such exposure can be readily achieved when high dose intermittent therapy is given.
Sunlight Vitamin D And Skin Cancer
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Author : Jörg Reichrath
language : en
Publisher: Springer Nature
Release Date : 2020-09-11
Sunlight Vitamin D And Skin Cancer written by Jörg Reichrath and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-11 with Medical categories.
The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.
Calcium Vitamin D And Prevention Of Colon Cancer
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Author : Martin Lipkin
language : en
Publisher: CRC Press
Release Date : 2018-01-18
Calcium Vitamin D And Prevention Of Colon Cancer written by Martin Lipkin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Medical categories.
These proceedings were published as a result of a workshop sponsored by the Chemoprevention Branch of the National Cancer Institute. The workshop covered a range of topics including calcium and vitamin D in human nutrition; epidemiologic relationships betweencalcium, vitamin D, and colon cancer; the biology of calium and vitamin D at the tissue and cellular level; and enimal and human studies investigating the potential for prevention of colon cancer with calcium and vitamin D.
Sunlight Vitamin D And Prostate Cancer Risk
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Author : P. J. Hyde
language : en
Publisher: Xlibris Corporation
Release Date : 2004-04
Sunlight Vitamin D And Prostate Cancer Risk written by P. J. Hyde and has been published by Xlibris Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04 with Light categories.
"Sunlight, Vitamin D, and Prostate Cancer Risk" P. J. Hyde This science-based book is the first to demonstrate that in prostate cancer, insufficient access to the sun's short wavelength ultraviolet-B irradiance, necessary for photosynthesis of vitamin D, increases the risk of progression. The author surveys five populations with steeply elevated mortality from prostate cancer: African-North Americans, Norwegians, Swedes, Swiss and Danes. He finds that insufficient exposure to UV-B and inadequate photosynthesis of vitamin D is common to them all. Based on data extracted from World Health Statistics Annuals published in hard copy by the World Health Organization (WHO) in the 1980s, graphs depicting age-specific rates of prostate cancer mortality in Western European countries show that the Swiss rates are anomalously high for the country's latitude and may even surpass the rates for Norway and Sweden. Age-standardized (world) statistics published on-line by the WHO's International Agency for Research into Cancer (IARC) in its Globocan 2000 Cancer Epidemiology Database list identical rates for Norway, Sweden and Switzerland. The age-specific and age-standardized rates of prostate cancer mortality reported for other northern alpine countries are normal for the latitudes. Their more extensive surface areas and dispersed populations, with the great majority of their citizens residing far from the Alps, are consistent with this. In a population survey conducted by Swiss scientists from two institutions, blood levels of calcidiol (25-hydroxyvitamin D), the body's major circulating reservoir of the vitamin, were measured in a large representative sample of adults in all age groups. Subjects older than 65 were found to be spending less than 30 minutes a day outdoors in the summer. This is significant, because the capacity of exposed skin to photosynthesize vitamin D declines with age. Moreover, its inverse correlation with the intensiveness of pigmentation means that African-North Americans in particular need to spend longer periods of time in direct sunlight than may be possible for a variety of reasons. The book contends that many aging individuals residing far from the Equator can achieve year-round sufficiency in vitamin D through relatively frequent, brief periods of exposure to sunlight, reinforced in winter by adequate supplementation. Published research indicating how many international units of the vitamin may be needed daily is also discussed. There is a detailed description of the mechanism whereby minute quantities of a powerful steroid hormone (calcitriol) metabolized from calcidiol, bind to the hormone's receptors (VDR) within the nuclei of the cells. By a signalling procedure involving "cross talk" between the hormone and the VDR, and resulting changes in the transcription of genes within the nuclei, proliferation of malignant cells can be inhibited. Besides prostate cancer, several other common cancers are reported to be associated with deficiencies of vitamin D. "Recommended reading for anyone interested in lowering their risk of prostate cancer"---Christopher Morash, MD, FRCSC, Chief of Urosurgical Oncology, Ottawa Regional Cancer Centre, Ottawa, Ontario. ISBN: 1-4010-8258-0 (paperback) and 1-4010-8259-9 (hardback). Surface: Xlibris Corporation at International Plaza II, Suite 340, Philadelphia, PA, U.S.A. 19113 Web: http://www.xlibris.com/bookstore/bookdisplay.asp'bookid=17092 Email: [email protected] Price (paperback): U
Vitamin D
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Author : Michael F. Holick
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-27
Vitamin D written by Michael F. Holick and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-27 with Medical categories.
In Vitamin D: Physiology, Molecular Biology, and Clinical Applications, Second Edition, leading researchers provide a comprehensive, highly readable overview of the biological functions and clinical applications of vitamin D and its metabolites. Topics range from the most recent recommendations for vitamin D intake to new approaches for the treatment and prevention of vitamin D deficiency and the development of active vitamin D drugs to treat psoriasis and cancer. The book demonstrates the significant role that vitamin D has in maintaining good bone health and the prevention of osteoporosis, an important health problem for adults over the age of fifty. In addition, it authoritatively reviews the relationship between sunlight exposure, vitamin D, and increased risk of colon and breast cancer; how vitamin D is made in the skin; and the sequence of events that leads to its activation by the kidney. Also examined are the biological functions of 1,25-dihydrovitamin D3 on the intestine and bone, as well as other tissues, such as skin, the immune system, prostate, and breast, and vitamin D's molecular mechanism of action on the cell membrane and nucleus. The first edition of Vitamin D: Physiology, Molecular Biology and Clinical Applications was the benchmark in the field when published in 1999. This new and expanded volume continues to include extensive, in-depth chapters covering the most important aspects of the complex interactions between vitamin D and other dietary components, the ongoing debate concerning the best indicator of optimal vitamin D status and its nutrient requirements, and the impact of less than optimal status on disease risk. Vitamin D: Physiology, Molecular Biology, and Clinical Applications, Second Edition is designed and organized not only to be an up-to-date review on the subject, but also to provide medical students, graduate students, health care professionals and even the lay public with a reference source for the most up-to-date information about the vitamin D deficiency pandemic and its clinical implications for health and disease.
Drug Resistance In Cancer Cells
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Author : Kapil Mehta
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-12
Drug Resistance In Cancer Cells written by Kapil Mehta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-12 with Medical categories.
It was estimated that in 2008, 1,437,180 patients would receive a new cancer diagnosisand 565,650individualswould die of cancer (Jemal et al. 2008).Since the vast majority of patients dying of cancer will have had anticancer therapy, both c- ventional chemotherapy and novel targeted therapy, it can be concluded that these patients are dying with drug resistant cancer. The term multidrug resistance is also apt – in that these patients die after having undergone multiple rounds of different and structurally unrelated cancer therapies. However, for some, the concept of m- tidrug resistance is a worn out idea, stemming from disappointment with the drug resistancereversalstrategiesthatwerecarriedoutinthe1990susingpumpinhibitors to block drug resistance mediated by P-glycoprotein, product of the MDR-1 gene. However, if one takes the larger de?nition – multidrug resistance as simultaneous resistance to multiple structurally unrelated anticancer therapies – its existence c- not be denied. The purpose of this book is to explore new concepts related to drug resistance in cancer, including resistance to the new molecularly targeted agents. Perhaps new terminology is needed for resistance that occurs following therapy with the targeted agents: Novel Targeted Agent Resistance (NTR). Alternatively, we can return to the original de?nition of multidrug resistance as simply the res- tance to multipleagents that occurs in the course of normalcancer progression.This resistance is likely to be mediated by many factors.
Vitamin D For Dummies
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Author : Alan L. Rubin
language : en
Publisher: John Wiley & Sons
Release Date : 2011-05-23
Vitamin D For Dummies written by Alan L. Rubin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-23 with Health & Fitness categories.
Your plain-English guide to the many benefits of Vitamin D Vitamin D is in the news every day, as new tests and studies reveal encouraging information about its power in maintaining good health and preventing major illnesses. No longer thought to just play a role in calcium intake and bone growth, Vitamin D has a host of other functions in the body, playing a role in prevention of serious diseases, including cancer, diabetes, and heart disease, as well as boosting immunity, improving athletic performance, losing weight, and more. This hands-on, plain-English guide is perfect for anyone looking for helpful advice and information on the "nutrient of the decade." Coverage of how Vitamin D works, and how much is needed for disease prevention How and where to get sufficient amounts of the right kind of Vitamin D – from both your diet and nutritional supplements The best ways to maintain healthy levels of Vitamin D If you're looking to learn more about the many benefits Vitamin D can have on you and your family, you'll find everything you need right here.
Cancer Prevention
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Author : H. L. Bradlow
language : en
Publisher: New York Academy of Sciences
Release Date : 2000-06
Cancer Prevention written by H. L. Bradlow and has been published by New York Academy of Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-06 with Family & Relationships categories.
The most recent advances in cancer prevention specifically in the areas of genetics, molecular biology, screening, and preventive trials are explored in depth by clinicians and researchers from around the world. The clinician will be able to apply this information to his or her practice, while the research scientist will gain insight into the clinical issues of prevention and early detection of cancer. Particular emphasis is placed on the prevention of breast, colon, and prostate cancer.