Cancer Diagnostics With Dna Microarrays
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Cancer Diagnostics With Dna Microarrays
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Author : Steen Knudsen
language : en
Publisher: John Wiley & Sons
Release Date : 2006-11-03
Cancer Diagnostics With Dna Microarrays written by Steen Knudsen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-03 with Science categories.
Authored by an international authority in the field,Cancer Diagnostics with DNA Microarrays is a complete reference work on the rapidly growing use of DNA microarray data in the diagnosis of and treatment planning for a large number of human cancers. Uniquely deals with direct clinical application of microarray data to oncology diagnosis, leading to more effective diagnosis of and clearer treatment regimens for a wide range of human cancers Offers clinicians summary presentation of state-of-the-art science of DNA microarrays Each chapter includes bibliographic and further reading suggestions Easily accessible, assuming no special training in statistics or bioinformatics Replete with examples and mini-cases, Cancer Diagnostics with DNA Microarrays offers cancer researchers in private, pharmacologic, and governmental institutions, biomedical statisticians, and practicing oncologists concise, thoughtfully authored guidance on the use of microarray data and analysis as clinical tools. The text carefully addresses the needs of end users – researchers and physicians – using microarrays as a tool to be applied in common clinical situations, and is of interest for students in medicine and biology and professionals in health care as well.
Cancer Diagnostics
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Author : Robert M. Nakamura
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-07-16
Cancer Diagnostics written by Robert M. Nakamura and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07-16 with Medical categories.
Reviews recent and emerging clinical laboratory tests that can help in the early detection, evaluation, and prediction of human tumors. Emphasizing the importance of molecular and genetic RNA/DNA tets that detect persons at high risk for specific cancers, the authors explore these novel serological assays, cellular assays useful for anatomic pathology, and molecular and genetic assays.
Biosensor Based Advanced Cancer Diagnostics
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Author : Raju Khan
language : en
Publisher: Academic Press
Release Date : 2021-08-25
Biosensor Based Advanced Cancer Diagnostics written by Raju Khan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-25 with Technology & Engineering categories.
Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient's life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. - Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers - Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications - Offers an insight into how to develop cost-effective diagnostics for early detection of cancer
Molecular Diagnostics Of Cancer
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Author : Pier Paolo Piccaluga
language : en
Publisher: BoD – Books on Demand
Release Date : 2024-04-10
Molecular Diagnostics Of Cancer written by Pier Paolo Piccaluga and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-10 with Science categories.
Precision medicine, also known as personalized medicine, is an innovative approach to medical treatment and diagnosis that takes into account individual variability in genes, environment, and lifestyle for each person. In the context of cancer, precision medicine aims to tailor medical care to the specific genetic and molecular characteristics of each patient's tumor. This allows for more targeted and effective treatments, minimizing side effects and improving outcomes. The first step in precision medicine, especially in oncology, is represented by an accurate diagnosis, including molecular and genetic data. A comprehensive assessment in molecular pathology includes conventional and more innovative techniques, including polymerase chain reaction (PCR)-based approaches, Sanger sequencing, and next-generation sequencing for genomic profiling. Precision medicine relies on the analysis of the patient's genomic information, including the DNA mutations present in their tumor. Genomic profiling helps identify specific genetic alterations that are driving the growth of cancer cells. This information is crucial for selecting targeted therapies that directly interfere with these specific molecular abnormalities. In addition, molecular diagnostics provide: • biomarker identification • tumor heterogeneity assessment In turn, this translates into direct treatment decision support. The information obtained through molecular tests guides oncologists in making more informed decisions about the most appropriate treatments for individual patients. This can include targeted therapies, immunotherapies, or other interventions based on the specific molecular profile of the tumor. Prognostication becomes treatment-specific (prediction) and predictive models can be developed by integrating genetic and molecular data with clinical information, to estimate the likelihood of treatment response, recurrence, and overall prognosis. Overall, molecular pathology has significantly advanced cancer diagnostics and treatment, leading to improved outcomes and a shift toward more personalized and effective care. The integration of molecular diagnostics and genomic information has transformed how cancer is understood and managed, offering new hope for patients and providing oncologists with powerful tools to combat the complexity of the disease.
Microarray Technology And Cancer Gene Profiling
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Author : Simone Mocellin
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-28
Microarray Technology And Cancer Gene Profiling written by Simone Mocellin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-28 with Medical categories.
Cancer is a heterogeneous disease in most respects, including its cellularity, different genetic alterations and diverse clinical behaviors. Traditional molecular analyses are reductionist, assessing only one or a few genes at a time, thus working with a biologic model too specific and limited to confront a process whose clinical outcome is likely to be governed by the combined influence of many genes. The potential of functional genomics is enormous, because for each experiment, thousands of relevant observations can be made simultaneously. Accordingly, DNA array, as other high throughput technologies, might catalyze and ultimately accelerate the development of knowledge in tumor cell biology. Although in its infancy, the implementation of DNA array technology in cancer research has already provided investigators with novel data and intriguing new hypotheses on the molecular cascade leading to cancerogenesis, tumor aggressiveness and sensitivity to antineoplastic agents. Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, principles of DNA array-based tumor gene profiling need to be clearly understood for the data to be correctly interpreted and appreciated. In the present book, written by leading experts in each field, the technical features characterizing this powerful laboratory tool are discussed, and the applications so far described in the field of oncology are reviewed.
Bio Engineering Approaches To Cancer Diagnosis And Treatment
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Author : Azadeh Shahidian
language : en
Publisher: Academic Press
Release Date : 2020-05-14
Bio Engineering Approaches To Cancer Diagnosis And Treatment written by Azadeh Shahidian and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-14 with Technology & Engineering categories.
Bioengineering Approaches to Cancer Diagnosis and Treatment is written for an audience of senior undergraduate students and graduate students in mechanical, electrical and biomedical engineering fields and other professionals in medicine. It is ideally structured for teaching and for those who are working in cancer bioengineering or interdisciplinary projects. The book's authors bring a unique perspective from their expertise in immunology, nanobiomaterials and heat transfer. Topical coverage includes an introduction to the fundamentals of bioengineering and engineering approaches for cancer diagnosis, cancer treatment via case studies, and sections on imaging, immunotherapy, cell therapy, drug delivery, ultrasound and microfluidics in cancer treatment. - Provides fully supported case studies relating to cancer diagnosis and therapy - Pairs the basic fundamentals of engineering and biomedical engineering and applies them to the diagnosis of cancer
Computational Intelligence In Cancer Diagnosis
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Author : Janmenjoy Nayak
language : en
Publisher: Academic Press
Release Date : 2023-04-12
Computational Intelligence In Cancer Diagnosis written by Janmenjoy Nayak and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-12 with Science categories.
Computational Intelligence in Cancer Diagnosis: Progress and Challenges provides insights into the current strength and weaknesses of different applications and research findings on computational intelligence in cancer research. The book improves the exchange of ideas and coherence among various computational intelligence methods and enhances the relevance and exploitation of application areas for both experienced and novice end-users. Topics discussed include neural networks, fuzzy logic, connectionist systems, genetic algorithms, evolutionary computation, cellular automata, self-organizing systems, soft computing, fuzzy systems, and hybrid intelligent systems. The book's chapters are written by international experts from both cancer research, oncology and computational sides to cover different aspects and make it comprehensible for readers with no background on informatics. - Contains updated information about advanced computational intelligence, spanning the areas of neural networks, fuzzy logic, connectionist systems, genetic algorithms, evolutionary computation, cellular automata, self-organizing systems, soft computing, fuzzy systems, and hybrid intelligent systems in diagnosing cancer diseases - Discusses several cancer types, including their detection, treatment and prevention - Presents case studies that illustrate the applications of intelligent computing in data analysis to help readers to analyze and advance their research in cancer
Omics Technologies In Cancer Biomarker Discovery
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Author : Xuewu Zhang
language : en
Publisher: CRC Press
Release Date : 2011-03-10
Omics Technologies In Cancer Biomarker Discovery written by Xuewu Zhang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-10 with Science categories.
The early detection of human cancer is still one of the great challenges in the battle against this disease. Single biomarkers are not likely to provide sufficient diagnostic power and multibiomarker assays should be developed in order to reach high diagnostic accuracy for cancer screening at the population level. Omics technologies are emerging ne
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 2000
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medicine categories.
Mammalian Genomics
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Author : Anatoly Ruvinsky
language : en
Publisher: CABI
Release Date : 2005
Mammalian Genomics written by Anatoly Ruvinsky and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.
Organization of the Mammalian Genome; Linkage mapping ; Mapping genomes at the chromosome leveI ; Mapping genomes at the molecular level ; DNA sequence of the human and other mammalian genomes; Expression of the Mammalian Genomes ; The transcriptome ; The proteome ; The epigenome: epigenetic reguIation of gene expression in mammalian species ; Regulation of genome activity and genetic networks in mammals ; Inducing alterations in the mammalian genome for investigating the functions : of genes ; Evolution of the Mammalian Genome ; O A comparative analysis of mammalian genomics: prokaryote and eukaryote perspectives ; Elements and mechanisms of genome change ; DNA sequence evolution and phylogenetic footprinting ; Evolution of the mammalian karyotype ; Compara tive gene mapping, chromosome painting and the reconstruction of the ancestral mammalian karyotype ; Genome Analysis and Bioinformatics ; Bioinformatics: from computational analysis through to integrated systems ; Genetic databases ; Gene predictions and annotations ; The Fruits of Mammalian Genomics ; Genomic research and progress in understanding inherited disorders in humans and other mammals ; Pharmacogenomics ; O Genome scanning for quantitative trait loci ; Mammalian popuIation genetics and genomics.