Microarray Technology And Cancer Gene Profiling
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Microarray Technology And Cancer Gene Profiling
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Author : Simone Mocellin
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-28
Microarray Technology And Cancer Gene Profiling written by Simone Mocellin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-28 with Medical categories.
Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated. This book, written by leading experts, discusses the technical features characterizing the powerful laboratory tool of microarray technology, and reviews applications in the field of oncology.
Microarray Technology And Cancer Gene Profiling
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Author : Simone Mocellin
language : en
Publisher: Springer
Release Date : 2008-11-01
Microarray Technology And Cancer Gene Profiling written by Simone Mocellin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-01 with Medical categories.
Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated. This book, written by leading experts, discusses the technical features characterizing the powerful laboratory tool of microarray technology, and reviews applications in the field of oncology.
Dna Microarray Technology And Data Analysis In Cancer Research
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Author : Shaoguang Li
language : en
Publisher: World Scientific
Release Date : 2009-02-04
Dna Microarray Technology And Data Analysis In Cancer Research written by Shaoguang Li and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-04 with Medical categories.
DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology.
Cancer Gene Profiling
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Author : Robert Grützmann
language : en
Publisher: Humana Press
Release Date : 2009-11-06
Cancer Gene Profiling written by Robert Grützmann and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-06 with Medical categories.
Over the last few years, the methods for analyzing cancer-related genes on a molecular level have changed rapidly. The advent of incredible new technology, such as automated sequencing, has served as a catalyst for many advances in the area of gene profiling, and has enabled the research community to investigate populations of cells in a given tissue. Cancer Gene Profiling: Methods and Protocols examines the world of cancer gene profiling in light of these new advances, providing highly developed microarray techniques alongside modern methods for arraying tissues and proteomics. Chapters bring together the experiences of leading scientists in each method of profiling, providing a clear overview of the ground-breaking techniques used to perform these experiments effectively. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and state-of-the-art, Cancer Gene Profiling: Methods and Protocols is a fundamental guidebook for researchers in the field of cancer gene profiling, as well as for those individuals in the area of biomedical/translational research.
Gene Expression Profiling By Microarrays
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Author : Wolf-Karsten Hofmann
language : en
Publisher: Cambridge University Press
Release Date : 2006-06-22
Gene Expression Profiling By Microarrays written by Wolf-Karsten Hofmann and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-22 with Medical categories.
Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously, and offers a new means to classify cancer and other diseases. Gene expression profiling can also be used to predict clinical outcome and response to specific therapeutic agents. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Investigators in oncology, pharmacology and related clinical sciences, as well as basic scientists, will value this review of a promising new diagnostic and prognostic technology.
Cancer Diagnostics With Dna Microarrays
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Author : Steen Knudsen
language : en
Publisher: John Wiley & Sons
Release Date : 2006-11-03
Cancer Diagnostics With Dna Microarrays written by Steen Knudsen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-03 with Science categories.
Authored by an international authority in the field,Cancer Diagnostics with DNA Microarrays is a complete reference work on the rapidly growing use of DNA microarray data in the diagnosis of and treatment planning for a large number of human cancers. Uniquely deals with direct clinical application of microarray data to oncology diagnosis, leading to more effective diagnosis of and clearer treatment regimens for a wide range of human cancers Offers clinicians summary presentation of state-of-the-art science of DNA microarrays Each chapter includes bibliographic and further reading suggestions Easily accessible, assuming no special training in statistics or bioinformatics Replete with examples and mini-cases, Cancer Diagnostics with DNA Microarrays offers cancer researchers in private, pharmacologic, and governmental institutions, biomedical statisticians, and practicing oncologists concise, thoughtfully authored guidance on the use of microarray data and analysis as clinical tools. The text carefully addresses the needs of end users – researchers and physicians – using microarrays as a tool to be applied in common clinical situations, and is of interest for students in medicine and biology and professionals in health care as well.
Microarray Innovations
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Author : Gary Hardiman
language : en
Publisher: CRC Press
Release Date : 2009-04-02
Microarray Innovations written by Gary Hardiman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-02 with Medical categories.
In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarr
Gene Expression Profiling Of Uv Induced Skin Cancer Using Cdna Microarray Technology
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Author :
language : en
Publisher:
Release Date : 2001
Gene Expression Profiling Of Uv Induced Skin Cancer Using Cdna Microarray Technology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Expression Profiling Of Human Tumors
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Author : Marc Ladanyi
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-05-01
Expression Profiling Of Human Tumors written by Marc Ladanyi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-01 with Medical categories.
A comprehensive review of the use of global gene expression profiling to understand human tumors. The authors focus on the analysis of human tissue samples for a variety of cancers, including breast, colorectal, lung, renal, ovarian, bone, and brain tumors, among others. A primer on the technology and its novel analytical methods. Contains over 40 color images. Explains both the theory and practice of comprehensive gene expression profiling. Timely and topical, Expression Profiling of Human Tumors: Diagnostic and Research Applications offers every oncologist, pathologists, and cancer surgeons an essential introduction to the most promising new high-throughput investigative approaches in molecular biology-technology that is already dramatically reshaping the future of cancer research, diagnostic pathology, and clinical oncology.
Gene Expression Profiling Of Uv Induced Skin Cancer Using Cdna Microarray Technology
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Author : Brandon George Howell
language : en
Publisher:
Release Date : 2001
Gene Expression Profiling Of Uv Induced Skin Cancer Using Cdna Microarray Technology written by Brandon George Howell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Ultraviolet (UV) light represents a complete carcinogen, and it is implicated in causing the most prevalent form of skin cancer, basal cell carcinoma (BCC). Previous studies have shown that UV can induce profound changes in cutaneous gene expression leading to immune suppression, which contributes to cutaneous malignancy. This research thesis was undertaken to establish the use of cDNA microarray technology for examining gene expression profiles in the skin. To establish the technique, we first examined UV effects on keratinocytes. Several UV-regulated genes were discovered including the endogenous angiogenesis inhibitor thrombospondin-1, which is potentially relevant to UV-induced carcinogenesis. To examine genes regulated in skin cancer more directly, biopsies from 50 BCC patients were analyzed by microarray. The differential gene expression data obtained for these patients, in addition to the in vitro UV-inducible genes, may promote further understanding of genetic processes involved in non-melanoma skin cancer.