Cancer Gene Profiling
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Microarray Technology And Cancer Gene Profiling
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Author : Simone Mocellin
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-28
Microarray Technology And Cancer Gene Profiling written by Simone Mocellin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-28 with Medical categories.
Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated. This book, written by leading experts, discusses the technical features characterizing the powerful laboratory tool of microarray technology, and reviews applications in the field of oncology.
Cancer Gene Profiling
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Author : Robert Grützmann
language : en
Publisher: Humana Press
Release Date : 2009-11-06
Cancer Gene Profiling written by Robert Grützmann and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-06 with Medical categories.
Over the last few years, the methods for analyzing cancer-related genes on a molecular level have changed rapidly. The advent of incredible new technology, such as automated sequencing, has served as a catalyst for many advances in the area of gene profiling, and has enabled the research community to investigate populations of cells in a given tissue. Cancer Gene Profiling: Methods and Protocols examines the world of cancer gene profiling in light of these new advances, providing highly developed microarray techniques alongside modern methods for arraying tissues and proteomics. Chapters bring together the experiences of leading scientists in each method of profiling, providing a clear overview of the ground-breaking techniques used to perform these experiments effectively. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and state-of-the-art, Cancer Gene Profiling: Methods and Protocols is a fundamental guidebook for researchers in the field of cancer gene profiling, as well as for those individuals in the area of biomedical/translational research.
Gene Expression Profiling In Cancer
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Author : Dimitrios Vlachakis
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-06-19
Gene Expression Profiling In Cancer written by Dimitrios Vlachakis and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-19 with Medical categories.
The contribution of modern-day genetics in designing efficient gene expression profiles for cancer is immense. The progress of technology and science in recent years provides the opportunity for discovery and application of new techniques for treating various diseases that affect humanity. Methods for finding and analyzing the profile of gene expression of infected cells give scientists the ability to develop more targeted and effective treatments, especially for diseases such as cancer. The development of gene expression profiling is one of the most important achievements in cancer genetics in our time. It is essentially the driving force behind personalized and precision medicine. This book highlights recent developments, applications, and breakthroughs in the field of gene expression profiling in cancer.
Cancer Gene Profiling
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Author : Robert Grützmann
language : en
Publisher:
Release Date : 2016
Cancer Gene Profiling written by Robert Grützmann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Cancer categories.
This second edition volume brings together the experiences of leading scientists in the discipline of cancer gene profiling. Because cancer genes can be profiled in many different ways, Cancer Gene Profiling: Methods and Protocols, Second Edition explores different techniques and approaches needed to understand the key stages of cancer development, as using only one technique would be insufficient. This book provides readers with an overview of the state-of-the-art methods that will enable them to perform these experiments, and demonstrates the kind of analysis that is possible in our current biomedical research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Cancer Gene Profiling: Methods and Protocols, Second Edition is a great resource for any student or practitioner with an interest in cancer gene profiling, and can be used in any well-equipped research laboratory.
Microarray Technology And Cancer Gene Profiling
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Author : Simone Mocellin
language : en
Publisher: Springer
Release Date : 2008-11-01
Microarray Technology And Cancer Gene Profiling written by Simone Mocellin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-01 with Medical categories.
Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated. This book, written by leading experts, discusses the technical features characterizing the powerful laboratory tool of microarray technology, and reviews applications in the field of oncology.
Impact Of Gene Expression Profiling Tests On Breast Cancer Outcomes
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Author : Luigi Marchionni
language : en
Publisher: DIANE Publishing
Release Date : 2009-05
Impact Of Gene Expression Profiling Tests On Breast Cancer Outcomes written by Luigi Marchionni and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05 with Medical categories.
Assesses the evidence that three marketed gene expression-based assays improve prognostic accuracy, treatment choice, and health outcomes in women diagnosed with early stage breast cancer. Three gene expression assays were evaluated; Oncotype DX¿, MammaPrint® and the Breast Cancer Profiling (BCP or H/I ratio) test, and for gene expression signatures underlying the assays. They sought evidence on: analytic performance of tests; clinical validity; clinical utility; harms; and impact on clinical decision making and health care costs. Conclusions: Oncotype DX is furthest along the validation pathway, with retrospective evidence that it predicts distant spread and chemotherapy benefit to a clinically relevant extent over standard predictors. Illus.
Fast Facts Comprehensive Genomic Profiling
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Author : Bernardo L. Rapoport
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2020-10-20
Fast Facts Comprehensive Genomic Profiling written by Bernardo L. Rapoport and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-20 with Medical categories.
Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: • Genetic mutations and biomarkers • Understanding next-generation sequencing • Elements of comprehensive genomic profiles • Role in precision oncology • Predictive and prognostic biomarkers • Overcoming barriers to genotype-directed therapy
Expression Profiling Of Human Tumors
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Author : Marc Ladanyi
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-05-01
Expression Profiling Of Human Tumors written by Marc Ladanyi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-01 with Medical categories.
A comprehensive review of the use of global gene expression profiling to understand human tumors. The authors focus on the analysis of human tissue samples for a variety of cancers, including breast, colorectal, lung, renal, ovarian, bone, and brain tumors, among others. A primer on the technology and its novel analytical methods. Contains over 40 color images. Explains both the theory and practice of comprehensive gene expression profiling. Timely and topical, Expression Profiling of Human Tumors: Diagnostic and Research Applications offers every oncologist, pathologists, and cancer surgeons an essential introduction to the most promising new high-throughput investigative approaches in molecular biology-technology that is already dramatically reshaping the future of cancer research, diagnostic pathology, and clinical oncology.
Gene Profiles In Drug Design
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Author : Brett A. Lidbury
language : en
Publisher: CRC Press
Release Date : 2008-07-10
Gene Profiles In Drug Design written by Brett A. Lidbury and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-10 with Medical categories.
With the successful mapping of the human genome, we have entered an age of unprecedented opportunity in which researchers are beginning to apply this vast repository of knowledge to the treatment of human disease. Gene-profiling technologies and the concept of individualized medicine are leading to the development of drugs with enhanced specificity
Gene Profiling In Breast Cancer
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Author :
language : en
Publisher:
Release Date : 2009
Gene Profiling In Breast Cancer written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.