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Cardiac Remodeling New Insights In Physiological And Pathological Adaptations


Cardiac Remodeling New Insights In Physiological And Pathological Adaptations
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Cardiac Remodeling New Insights In Physiological And Pathological Adaptations


Cardiac Remodeling New Insights In Physiological And Pathological Adaptations
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Author : Leonardo Roever
language : en
Publisher: Frontiers Media SA
Release Date : 2017-11-15

Cardiac Remodeling New Insights In Physiological And Pathological Adaptations written by Leonardo Roever and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-15 with Electronic book categories.


The effective management of Cardiac remodeling(CR), remains a major challenge. Heart failure remains the leading cause of death in industrialized countries. Yet, despite the enormity of the problem, effective therapeutic interventions remain elusive. In fact, several initially promising agents were found to decrease mortality in patients recovering from myocardial infarction. Cardiac remodeling is defined as molecular and interstitial changes, manifested clinically by changes in size, mass , geometry and function of the heart in response to certain aggression. Initially, ventricular remodeling aims to maintain stable cardiac function in situations of aggression.



Cellular Molecular And Environmental Contribution In Cardiac Remodeling


Cellular Molecular And Environmental Contribution In Cardiac Remodeling
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Author : Asim K. Duttaroy
language : en
Publisher: Elsevier
Release Date : 2024-04-16

Cellular Molecular And Environmental Contribution In Cardiac Remodeling written by Asim K. Duttaroy and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-16 with Science categories.


Cellular, Molecular and Environmental Contribution in Cardiac Remodeling: From Lab Bench to Clinical Perspective consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. It extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise and more. This book provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, and its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed. Provides a concise summary of recent developments in cardiac remodeling research, combining novel information and the latest data published in this field Discusses not only cellular and molecular factors impacting cardiac remodeling, but also environmental contributions such as lifestyle and exercise Identifies areas for future research and potential novel strategies for translating basic research knowledge to applications in patients



Cardiac Adaptations


Cardiac Adaptations
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Author : Bohuslav Ostadal
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-12

Cardiac Adaptations written by Bohuslav Ostadal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-12 with Medical categories.


This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation. Particular attention is paid to the still underestimated adaptive cardiac responses during development, to adaptation to the frequently occurring pressure and volume overload as well as to cardiac changes, induced by enduring exercise and chronic hypoxia. Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities.



Thyroid And Heart


Thyroid And Heart
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Author : Giorgio Iervasi
language : en
Publisher: Springer Nature
Release Date : 2020-03-19

Thyroid And Heart written by Giorgio Iervasi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-19 with Medical categories.


In recent years, several scientific papers have highlighted the role of the thyroid system in cardioprotection, and several clinical studies – including multicenter studies – have identified the role of thyroid hormones (TH) in the development and progression of cardiovascular disease, making an update of TH and heart relationship both necessary and timely. This second edition of Thyroid and Heart failure provides a careful and updated review of the experimental, clinical and epidemiological results in the field of TH and heart failure, with a particular focus on the translational - bench to bedside - significance of the obtained results. It discusses topics such as the molecular, structural, functional, cellular and histological cardiac changes; the reversibility of these changes with TH replacement therapy; the systemic effects – kidney, hormonal pathways systems, brain, muscle, etc – of altered TH metabolism in HF, as well as the clinical and prognostic implications. The section devoted to the potential therapeutic treatments has been expanded. Thanks to its translational approach to this highly complex subject, the book will be of interest to a broad readership, including cardiologists, endocrinologists and internists.



Insights In Integrative Physiology 2021


Insights In Integrative Physiology 2021
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Author : James Todd Pearson
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-24

Insights In Integrative Physiology 2021 written by James Todd Pearson and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-24 with Science categories.




Sports Health And Exercise Medicine


Sports Health And Exercise Medicine
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Author : Samuel Alexandre Almeida Hónorio
language : en
Publisher:
Release Date : 2020

Sports Health And Exercise Medicine written by Samuel Alexandre Almeida Hónorio and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Sports categories.




Muscle Cells


Muscle Cells
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Author : Mani T. Valarmathi
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-01-22

Muscle Cells written by Mani T. Valarmathi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-22 with Science categories.


The three different types of muscle tissue found in the animal kingdom are cardiac, skeletal, and smooth. The muscle cells are not only complex but also fascinating. In recent years there has been substantial advances in our understanding of muscle cell biology, especially in areas of molecular anatomy, basic physiology, understanding disease mechanisms, and therapeutic targets. Consequently, this book mainly focuses not only on the biology of myocytes, but also on all-encompassing disciplines pertaining to muscle tissue, such as fundamental physiology, molecular mechanisms of diseases, muscle regeneration, etc. for all three types of muscle, namely, skeletal, cardiac, and smooth muscle. As a result, the goal of this book is to consolidate the recent advances in the area of muscle biology/diseases/regeneration covering a broad range of interrelated topics in a timely fashion and to disseminate that knowledge in a lucid way to a greater scientific audience. This book will prove highly useful for students, researchers, and clinicians in muscle cell biology, exercise physiology/science, stem cell biology, developmental biology, cancer biology, pathology, oncology, as well as tissue engineering and regenerative medicine. This quick reference will benefit anyone desiring a thorough knowledge pertaining to recent advances in muscle biology in the context of health and disease.



G Protein Coupled Receptor Kinases Grks And Beta Arrestins New Insights Into Disease Regulators


G Protein Coupled Receptor Kinases Grks And Beta Arrestins New Insights Into Disease Regulators
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Author : Yuichi Hattori
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-10

G Protein Coupled Receptor Kinases Grks And Beta Arrestins New Insights Into Disease Regulators written by Yuichi Hattori and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-10 with categories.




Cardiac Regeneration


Cardiac Regeneration
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Author : Masaki Ieda
language : en
Publisher: Springer
Release Date : 2017-10-27

Cardiac Regeneration written by Masaki Ieda and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-27 with Medical categories.


This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.



Dilated Cardiomyopathy


Dilated Cardiomyopathy
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Author : Gianfranco Sinagra
language : en
Publisher: Springer
Release Date : 2019-05-17

Dilated Cardiomyopathy written by Gianfranco Sinagra and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-17 with Medical categories.


This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up. Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice. Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease.