Cardiotoxicity
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Cardiotoxicity Of Oncologic Treatments
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Author : Manuela Fiuza
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-03-28
Cardiotoxicity Of Oncologic Treatments written by Manuela Fiuza and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-28 with Medical categories.
The possibility of getting a cardiovascular disease or cancer increases with advancing age. At the same time, relevant improvements in cancer therapy have resulted in the improvement of quality of life and the increasement of the survival rate of such patients. As a result we have larger number of patients that experience the cardiac side effects of chemotherapy. The extent of cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, prior mediastinal radiotherapy and the presence of cardiovascular risk factors or history of heart disease. Early detection of the patients proneness for developing cardiotoxicity is the key issue to decrease morbidity and mortality. It also facilitates more tailored therapeutic interventions. Therefore, the collaboration and interaction of cardiology and oncology may contribute to reducing the cardiovascular adverse effects and improving the results in the treatment of patients with cancer.
Cardiotoxicity
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Author : Wenyong Tan
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-11-14
Cardiotoxicity written by Wenyong Tan and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-14 with Medical categories.
Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.
Cardiotoxicity Of Non Cardiovascular Drugs
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Author : Giorgio Minotti
language : en
Publisher: John Wiley & Sons
Release Date : 2010-03-25
Cardiotoxicity Of Non Cardiovascular Drugs written by Giorgio Minotti and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-25 with Science categories.
Some drugs which are not aimed at treating heart disease have nevertheless been found to have profound effects on heart muscle. Cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals.In recent years a number of non-cardiac blockbuster drugs such as terfenadine have been withdrawn from major markets because of cardiotoxicity concerns, while other drugs have either been withdrawn prior to marketing or required labelling changes that significantly restricted their use. In Cardiotoxicity of Non-Cardiovascular Drugs international experts describe the molecular mechanisms and clinical read-outs of cardiac events induced by a broad variety of noncardiovascular drugs. Particular emphasis is paid to the preclinical screening of drug cardiotoxicity. Topics include: metabolic targets of cardiotoxicity regulatory aspects translating molecular mechanisms into clinical trials structure-activity relationships in arrhythmias by antihistamines and psychoactive drugs cardiovascular toxicity of antitumor drugs cardiovascular toxicities of non-steroidal anti-inflammatory drugs cardiovascular toxicities of antiretroviral therapies Cardiotoxicity of Non-Cardiovascular Drugs is an essential guide to this important area of drug development. It will find a place on the bookshelves of researchers, regulators and students in medicinal chemistry, drug development, pharmacology, pharmacy and cardiovascular disease.
Anticancer Treatments And Cardiotoxicity
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Author : Patrizio Lancellotti
language : en
Publisher: Academic Press
Release Date : 2016-11-11
Anticancer Treatments And Cardiotoxicity written by Patrizio Lancellotti and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-11 with Medical categories.
Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients Written by world-leading experts in the field of cardiotoxicity Includes high-quality images, case studies, and test questions Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment
Cardiovascular Toxicity And Therapeutic Modalities Targeting Cardio Oncology
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Author : Imteyaz Qamar
language : en
Publisher: Academic Press
Release Date : 2022-05-26
Cardiovascular Toxicity And Therapeutic Modalities Targeting Cardio Oncology written by Imteyaz Qamar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-26 with Science categories.
Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. Anti-cancer treatment is associated with serious cardiovascular adverse events, including arterial and pulmonary hypertension, supraventricular and ventricular arrhythmias, systolic and diastolic cardiac dysfunction and coronary artery disease. Progress in cancer therapy over the past decades improved long-term survival but increased cancer therapy-related cardiotoxicity. Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications—arrhythmias, heart failure, and even death. Adopts a translational approach and comprehensively covers the basic science, mechanisms and concepts of cardio-oncology Outlines the current knowledge of biomarkers in cancer therapy-related cardiotoxicity Provides an understanding of the mechanisms of cardiovascular toxicity of various therapies that may lead to the identification of novel targets to reduce vascular complications
Recent Advances In Cardiotoxicity Testing
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Author : Tamer M. A. Mohamed
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-05
Recent Advances In Cardiotoxicity Testing written by Tamer M. A. Mohamed and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-05 with Science categories.
Drug Induced Cardiotoxicity Identification Assessment Prevention And Management
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Author : Feng Sun
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-01
Drug Induced Cardiotoxicity Identification Assessment Prevention And Management written by Feng Sun and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-01 with Medical categories.
Cardiotoxicity Of Oncologic Treatments
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Author : Manuela Fiuza
language : en
Publisher:
Release Date : 2012
Cardiotoxicity Of Oncologic Treatments written by Manuela Fiuza and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
The possibility of getting a cardiovascular disease or cancer increases with advancing age. At the same time, relevant improvements in cancer therapy have resulted in the improvement of quality of life and the increasement of the survival rate of such patients. As a result we have larger number of patients that experience the cardiac side effects of chemotherapy. The extent of cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, prior mediastinal radiotherapy and the presence of cardiovascular risk factors or history of heart disease. Early detection of the patients proneness for developing cardiotoxicity is the key issue to decrease morbidity and mortality. It also facilitates more tailored therapeutic interventions. Therefore, the collaboration and interaction of cardiology and oncology may contribute to reducing the cardiovascular adverse effects and improving the results in the treatment of patients with cancer.
Principles Of Cardiac Toxicology
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Author : Steven I. Baskin
language : en
Publisher: CRC Press
Release Date : 1991-09-23
Principles Of Cardiac Toxicology written by Steven I. Baskin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-09-23 with Medical categories.
What chemicals are poisonous to the heart and why are they toxic? Find out by reading Principles of Cardiac Toxicology. Certain chemicals can produce toxicity by interacting with elements of the cardiovascular system. This book presents the anatomical, physiological, biochemical, and pathological basis for this interaction and describes the
Anti Cancer Drug Induced Cardiotoxicity
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Author : Susan Currie
language : en
Publisher: Frontiers Media SA
Release Date : 2022-10-11
Anti Cancer Drug Induced Cardiotoxicity written by Susan Currie and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-11 with Medical categories.